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ziprasidone (Oral route)

30/06/10

zi-PRAS-i-done

Intramuscular routePowder for Solution

Increased Mortality in Elderly Patients with Dementia-Related Psychosis:
- Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 times to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Ziprasidone mesylate is not approved for the treatment of patients with dementia-related psychosis .

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Ziprasidone mesylate is not approved for the treatment of patients with dementia-related psychosis .

Oral routeCapsuleSuspension

Increased Mortality in Elderly Patients with Dementia-Related Psychosis
- Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 times to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis .

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s):

In the U.S.

Geodon

Available Dosage Forms:

Capsule

Therapeutic Class: Antipsychotic

Chemical Class: Benzisothiazoyl

Uses For ziprasidone

Ziprasidone is used to treat symptoms of psychotic (mental) disorders, such as schizophrenia, mania, or bipolar disorder. ziprasidone should not be used to treat behavioral problems in elderly patients who have dementia.

ziprasidone is available only with your doctor’s prescription.

Before Using ziprasidone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ziprasidone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ziprasidone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ziprasidone in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ziprasidone in the elderly. However, ziprasidone should not be used for behavioral problems in older adults with dementia.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using ziprasidone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Acecainide
Ajmaline
Amiodarone
Amisulpride
Aprindine
Arsenic Trioxide
Astemizole
Azimilide
Bepridil
Bretylium
Chloral Hydrate
Chloroquine
Chlorpromazine
Cisapride
Clarithromycin
Disopyramide
Dofetilide
Dolasetron
Dronedarone
Droperidol
Enflurane
Erythromycin
Flecainide
Fluconazole
Foscarnet
Gatifloxacin
Gemifloxacin
Halofantrine
Haloperidol
Halothane
Hydroquinidine
Ibutilide
Isoflurane
Isradipine
Levomethadyl
Lidoflazine
Lorcainide
Mefloquine
Mesoridazine
Methadone
Metoclopramide
Moxifloxacin
Octreotide
Pentamidine
Pimozide
Pirmenol
Prajmaline
Probucol
Procainamide
Prochlorperazine
Propafenone
Quinidine
Sematilide
Sertindole
Sotalol
Sparfloxacin
Spiramycin
Sultopride
Tacrolimus
Tedisamil
Telithromycin
Terfenadine
Thioridazine
Trifluoperazine
Vasopressin
Zolmitriptan
Zotepine

Using ziprasidone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Ajmaline
Amitriptyline
Amoxapine
Arsenic Trioxide
Chlorpromazine
Desipramine
Disopyramide
Doxepin
Fluoxetine
Hydromorphone
Hydroquinidine
Iloperidone
Imipramine
Lapatinib
Levofloxacin
Lumefantrine
Nilotinib
Nortriptyline
Pazopanib
Pirmenol
Prajmaline
Procainamide
Prochlorperazine
Protriptyline
Ranolazine
Sunitinib
Telavancin
Tetrabenazine
Trifluoperazine
Trimipramine

Using ziprasidone with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Carbamazepine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of ziprasidone

Take ziprasidone only as directed by your doctor even if you feel well. Do not take more of ziprasidone and do not take it more often than your doctor ordered. ziprasidone works best if there is a constant amount in the blood. To keep blood levels constant, take ziprasidone at the same time each day and do not miss any doses.

ziprasidone comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Swallow the capsule whole. Do not split, crush, or chew it.

You may take ziprasidone with food.

Dosing

The dose of ziprasidone will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of ziprasidone. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules):
- For bipolar disorder:
  - Adults—At first, 40 milligrams (mg) two times per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mg two times per day.
  - Children—Use and dose must be determined by your doctor.
- For schizophrenia:
  - Adults—At first, 20 milligrams (mg) two times per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mg two times per day.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of ziprasidone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using ziprasidone

It is very important that your doctor check your progress at regular visits to make sure that ziprasidone is working properly. Blood tests may be needed to check for unwanted effects.

ziprasidone can cause changes in the heart rhythm, such as a condition called QT prolongation. It may change the way your heart beats and cause fainting or serious side effects. Call your doctor right away if you have any symptoms of heart rhythm problems, such as fast, pounding, or irregular heartbeats.

Stop taking ziprasidone and check with your doctor right away if you have any of the following symptoms while using ziprasidone: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

ziprasidone may cause tardive dyskinesia (a movement disorder). Check with your doctor right away if you have lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs while you are using ziprasidone.

ziprasidone may increase the amount of sugar in your blood. Check with your doctor right away if you have increased thirst or increased urination. If you have diabetes, you may notice a change in the results of your urine or blood sugar tests. If you have any questions, check with your doctor.

Ziprasidone can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, a cough or hoarseness, lower back or side pain, or painful or difficult urination.

If you develop a skin rash, hives, or any allergic reaction to ziprasidone, stop using the medicine and check with your doctor as soon as possible.

ziprasidone may cause some people to become drowsy or dizzy, or to have trouble with thinking or controlling body movements. Make sure you know how you react to ziprasidone before you drive, use machines, or do anything else that requires you to be alert, well-coordinated, or able to think well.

Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Getting up slowly may help. If the problem continues or gets worse, check with your doctor.

Avoid activities involving high temperature or humidity. ziprasidone may reduce your body’s ability to adjust to the heat.

Ziprasidone may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies. If you or your caregiver notice any of these side effects, tell your doctor right away.

Avoid drinking alcohol while you are using ziprasidone.

ziprasidone may increase your weight. Your doctor may need to check your weight on a regular basis while you are using ziprasidone. Talk to your doctor about ways to prevent weight gain.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

ziprasidone Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Cough
difficulty with speaking
drooling
fear or nervousness
fever
inability to sit still
loss of balance control
muscle trembling, jerking, or stiffness
need to keep moving
restlessness
shuffling walk
sneezing
sore throat
stiffness of the limbs
twisting movements of the body
uncontrolled movements, especially of the face, neck, and back

Less common

Blurred vision
body aches or pain
chest pain
congestion
dizziness
fast, pounding, or irregular heartbeat or pulse
headache
hoarseness
nervousness
pounding in the ears
runny nose
slow or fast heartbeat
swelling of the tongue
tender, swollen glands in the neck
trouble with swallowing
voice changes

Rare

Fainting or feeling faint
feeling faint upon standing
persistent, painful erection
seizures

Incidence not known

Inability to move the eyes
increased blinking or spasms of the eyelid
sticking out of tongue
trouble with breathing, speaking, or swallowing
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual facial expressions

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Drowsiness
shakiness in the legs, arms, hands, or feet
sleepiness
slurred speech
trembling or shaking of the hands or feet

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach
belching
constipation
diarrhea
heartburn
indigestion
lack or loss of strength
nausea
rash
stomach discomfort, upset, or pain
weakness
weight gain

Less common

Blistering, crusting, irritation, itching, or reddening of the skin
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
change in vision
cracked, dry, or scaly skin
depression
difficulty with moving
dry mouth
increase in salivation
itching or reddening of the skin
joint pain
loss of appetite
muscle ache
muscle pains or stiffness
muscle tightness
stuffy nose
swelling
swollen joints
vomiting
weakness of the arms and legs
weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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ziprasidone (Intramuscular route)

30/06/10

zi-PRAS-i-done

Intramuscular routePowder for Solution

Increased Mortality in Elderly Patients with Dementia-Related Psychosis:
- Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 times to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Ziprasidone mesylate is not approved for the treatment of patients with dementia-related psychosis .

Oral routeCapsuleSuspension

Increased Mortality in Elderly Patients with Dementia-Related Psychosis
- Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 times to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis .

Elderly patients with dementia-related psychosis treated with atypical antipsychotic drugs are at an increased risk of death compared to placebo. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Observational studies suggest that antipsychotic drugs may increase mortality. It is unclear from these studies to what extent the mortality findings may be attributed to the antipsychotic drug as opposed to patient characteristics. Ziprasidone hydrochloride is not approved for the treatment of patients with dementia-related psychosis .

Commonly used brand name(s):

In the U.S.

Geodon

Available Dosage Forms:

Powder for Solution

Therapeutic Class: Antipsychotic

Chemical Class: Benzisothiazoyl

Uses For ziprasidone

Ziprasidone injection is used to treat agitation that occurs with schizophrenia, a mental disorder. ziprasidone should not be used to treat behavioral problems in elderly patients who have dementia.

ziprasidone is available only with your doctor’s prescription.

Before Using ziprasidone

Allergies

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ziprasidone injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ziprasidone injection in the elderly. However, ziprasidone should not be used for behavioral problems in older adults with dementia.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using ziprasidone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Acecainide
Ajmaline
Amiodarone
Amisulpride
Aprindine
Arsenic Trioxide
Astemizole
Azimilide
Bepridil
Bretylium
Chloral Hydrate
Chloroquine
Chlorpromazine
Cisapride
Clarithromycin
Disopyramide
Dofetilide
Dolasetron
Dronedarone
Droperidol
Enflurane
Erythromycin
Flecainide
Fluconazole
Foscarnet
Gatifloxacin
Gemifloxacin
Halofantrine
Haloperidol
Halothane
Hydroquinidine
Ibutilide
Isoflurane
Isradipine
Levomethadyl
Lidoflazine
Lorcainide
Mefloquine
Mesoridazine
Methadone
Metoclopramide
Moxifloxacin
Octreotide
Pentamidine
Pimozide
Pirmenol
Prajmaline
Probucol
Procainamide
Prochlorperazine
Propafenone
Quinidine
Sematilide
Sertindole
Sotalol
Sparfloxacin
Spiramycin
Sultopride
Tacrolimus
Tedisamil
Telithromycin
Terfenadine
Thioridazine
Trifluoperazine
Vasopressin
Zolmitriptan
Zotepine

Ajmaline
Amitriptyline
Amoxapine
Arsenic Trioxide
Chlorpromazine
Desipramine
Disopyramide
Doxepin
Fluoxetine
Hydromorphone
Hydroquinidine
Iloperidone
Imipramine
Lapatinib
Levofloxacin
Lumefantrine
Nilotinib
Nortriptyline
Pazopanib
Pirmenol
Prajmaline
Procainamide
Prochlorperazine
Protriptyline
Ranolazine
Sunitinib
Telavancin
Tetrabenazine
Trifluoperazine
Trimipramine

Carbamazepine

Interactions with Food/Tobacco/Alcohol

Proper Use of ziprasidone

A nurse or other trained health professional will give you ziprasidone. ziprasidone is given as a shot into one of your muscles.

Your doctor will give you a few doses of ziprasidone until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Precautions While Using ziprasidone

It is very important that your doctor check your progress at regular visits to make sure that ziprasidone is working properly. Blood tests may be needed to check for unwanted effects.

Check with your doctor right away if you have any of the following symptoms while using ziprasidone: convulsions (seizures), difficulty with breathing, a fast heartbeat, a high fever, high or low blood pressure, increased sweating, loss of bladder control, severe muscle stiffness, unusually pale skin, or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

Ziprasidone injection can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor right away if you think you are getting an infection, or if you have a fever or chills, a cough or hoarseness, lower back or side pain, or painful or difficult urination.

If you develop a skin rash, hives, or any allergic reaction to ziprasidone, stop using the medicine and check with your doctor as soon as possible.

Avoid activities involving high temperature or humidity. ziprasidone may reduce your body’s ability to adjust to the heat.

Ziprasidone injection may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies. If you or your caregiver notice any of these side effects, tell your doctor right away.

Avoid drinking alcohol while you are using ziprasidone.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

ziprasidone Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Chills
cold sweats
confusion
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

Less common

Anxiety
bleeding from rectum or bloody stools
blurred vision
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
change in personality
chest pain or discomfort
cough
diarrhea
difficulty with speaking
drooling
dry mouth
excessive muscle tone
feeling of warmth or heat
feeling that others are watching you or controlling your behavior
feeling that others can hear your thoughts
feeling, seeing, or hearing things that are not there
fever
flushing or redness of the skin, especially on the face and neck
general feeling of discomfort or illness
headache
hyperventilation
incremental or ratchet-like movement of the muscles
irregular heartbeats
irritability
joint pain
loss of appetite
loss of balance control
multiple swollen and inflamed skin lesions
muscle aches and pains
muscle discomfort
muscle tension or tightness
muscle trembling, jerking, or stiffness
nausea
nervousness
painful or prolonged erection of the penis
pounding in the ears
restlessness
rigid or stiff muscles
runny nose
severe mood or mental changes
shaking
shivering
shortness of breath
shuffling walk
slow or fast heartbeat
sore throat
stiffness of the limbs
sweating
trouble sleeping
twisting movements of the body
uncontrolled movements, especially of the face, neck, and back
unusual behavior
unusual tiredness or weakness
vomiting

Rare

Actions that are out of control
convulsions
difficulty with breathing
fainting
fast, pounding, or irregular heartbeat or pulse
high fever
high or low blood pressure
hives
itching
lip smacking or puckering
loss of bladder control
overactive reflexes
poor coordination
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
rapid or worm-like movements of the tongue
shivering
talking or acting with excitement you cannot control
trembling
twitching
unexpected or excess milk flow from the breasts
unusually pale skin
wheezing

More common

Pain at the site of injection
sleepiness or unusual drowsiness

Less common

Acid or sour stomach
back pain
belching
constipation
cramps
heartburn
heavy bleeding
inability to sit still
indigestion
need to keep moving
pain
runny nose
sleeplessness
sneezing
stomach discomfort, upset, or pain
stuffy nose
tooth disorder
unable to sleep
weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Zinx

30/06/10

Generic Name: zinc supplement (Oral route, Parenteral route)

Commonly used brand name(s):

In the U.S.

Galzin
M2 Zinc 50
Orazinc 110
Orazinc 220
Zinc-220
Zinc Chelated
Zn Plus Protein

In Canada

Prostavan

Available Dosage Forms:

Tablet
Capsule
Tablet, Extended Release

Uses For Zinx

Zinc supplements are used to prevent or treat zinc deficiency.

The body needs zinc for normal growth and health. For patients who are unable to get enough zinc in their regular diet or who have a need for more zinc, zinc supplements may be necessary. They are generally taken by mouth but some patients may have to receive them by injection.

Zinc supplements may be used for other conditions as determined by your health care professional.

Lack of zinc may lead to poor night vision and wound-healing, a decrease in sense of taste and smell, a reduced ability to fight infections, and poor development of reproductive organs.

Acrodermatitis enteropathica (a lack of absorption of zinc from the intestine)
Alcoholism
Burns
Type 2 diabetes mellitus
Down’s syndrome
Eating disorders
Intestine diseases
Infections (continuing or chronic)
Kidney disease
Liver disease
Pancreas disease
Sickle cell disease
Skin disorders
Stomach removal
Stress (continuing)
Thalassemia
Trauma (prolonged)

In addition, premature infants may need additional zinc.

Increased need for zinc should be determined by your health care professional.

Claims that zinc is effective in preventing vision loss in the elderly have not been proven. Zinc has not been proven effective in the treatment of porphyria.

Injectable zinc is given by or under the supervision of a health care professional. Other forms of zinc are available without a prescription.

Once a medicine or dietary supplement has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, zinc supplements are used in certain patients with the following medical condition:

Wilson’s disease (a disease of too much copper in the body)

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

Zinc is found in various foods, including lean red meats, seafood (especially herring and oysters), peas, and beans. Zinc is also found in whole grains; however, large amounts of whole-grains have been found to decrease the amount of zinc that is absorbed. Additional zinc may be added to the diet through treated (galvanized) cookware. Foods stored in uncoated tin cans may cause less zinc to be available for absorption from food.

The daily amount of zinc needed is defined in several different ways.

For U.S.—
Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person’s age, sex, and physical condition (e.g., pregnancy).
Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

For Canada—
Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Normal daily recommended intakes in milligrams (mg) for zinc are generally defined as follows:

Persons	U.S. (mg)	Canada (mg)
Infants and children birth to 3 years of age	5–10	2–4
Children 4 to 6 years of age	10	5
Children 7 to 10 years of age	10	7–9
Adolescent and adult males	15	9–12
Adolescent and adult females	12	9
Pregnant females	15	15
Breast-feeding females	16–19	15

Before Using Zinx

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts.

Geriatric

Problems in older adults have not been reported with intake of normal daily recommended amounts. There is some evidence that the elderly may be at risk of becoming deficient in zinc due to poor food selection, decreased absorption of zinc by the body, or medicines that decrease absorption of zinc or increase loss of zinc from the body.

Pregnancy

It is especially important that you are receiving enough vitamins and minerals when you become pregnant and that you continue to receive the right amount of vitamins and minerals throughout your pregnancy. The healthy growth and development of the fetus depend on a steady supply of nutrients from the mother. There is evidence that low blood levels of zinc may lead to problems in pregnancy or defects in the baby. However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.

Breast Feeding

It is important that you receive the right amounts of vitamins and minerals so that your baby will also get the vitamins and minerals needed to grow properly. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Interactions with Medicines

Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Amygdalin
Eltrombopag

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Proper Use of zinc supplement

This section provides information on the proper use of a number of products that contain zinc supplement. It may not be specific to Zinx. Please read with care.

Zinc supplements are most effective if they are taken at least 1 hour before or 2 hours after meals. However, if zinc supplements cause stomach upset, they may be taken with a meal. You should tell your health care professional if you are taking your zinc supplement with meals.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

For oral dosage forms (capsules, lozenges, tablets, extended-release tablets):
- To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of zinc. The dosage form [e.g., zinc gluconate, zinc sulfate] has a different strength):
  - For the U.S
  - Adult and teenage males—15 milligrams (mg) per day.
  - Adult and teenage females—12 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—16 to 19 mg per day.
  - Children 4 to 10 years of age—10 mg per day.
  - Children birth to 3 years of age—5 to 10 mg per day.
  - For Canada
  - Adult and teenage males—9 to 12 mg per day.
  - Adult and teenage females—9 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—15 mg per day.
  - Children 7 to 10 years of age—7 to 9 mg per day.
  - Children 4 to 6 years of age—5 mg per day.
  - Children birth to 3 years of age—2 to 4 mg per day.
- To treat deficiency:
  - Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss taking zinc supplements for one or more days there is no cause for concern, since it takes some time for your body to become seriously low in zinc. However, if your health care professional has recommended that you take zinc, try to remember to take it as directed every day.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Zinx

When zinc combines with certain foods it may not be absorbed into your body and it will do you no good. If you are taking zinc, the following foods should be avoided or taken 2 hours after you take zinc:

Bran
Fiber-containing foods
Phosphorus-containing foods such as milk or poultry
Whole-grain breads and cereals

Do not take zinc supplements and copper, iron, or phosphorus supplements at the same time. It is best to space doses of these products 2 hours apart, to get the full benefit from each dietary supplement.

Zinx Side Effects

Along with its needed effects, a dietary supplement may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare – With large doses

Chills
continuing ulcers or sores in mouth or throat
fever
heartburn
indigestion
nausea
sore throat
unusual tiredness or weakness

Symptoms of overdose

Chest pain
dizziness
fainting
shortness of breath
vomiting
yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Zincon

30/06/10

Generic Name: pyrithione (Topical route)

pir-i-THYE-one

Commonly used brand name(s):

In the U.S.

2 in 1 Dandruff
Beta Med
DermaZinc
DHS Zinc
Skincure
Zincon
Znp

Available Dosage Forms:

Shampoo
Spray
Cream
Bar
Lotion
Soap

Therapeutic Class: Dermatological Agent

Chemical Class: Pyrethrums

Uses For Zincon

Pyrithione is used to help control the symptoms of dandruff and seborrheic dermatitis of the scalp.

This medicine is available without a prescription.

Before Using Zincon

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of pyrithione in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of pyrithione in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Proper Use of pyrithione

This section provides information on the proper use of a number of products that contain pyrithione. It may not be specific to Zincon. Please read with care.

For best results, use this medicine at least 2 times a week or as directed by your doctor.

To use:

Before applying this shampoo, wet the hair and scalp with lukewarm water.
Apply enough shampoo to the scalp to work up a lather and rub in well, then rinse.
Apply the shampoo again and rinse thoroughly.

Keep this medicine away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

For bar dosage form:
- For dandruff and seborrheic dermatitis:
  - Adults and children—Apply to the affected skin of body, face, or scalp once a day at least two times a week. Lather, massage into affected area, rinse, and repeat.

For cream dosage forms:
- For dandruff or seborrheic dermatitis:
  - Adults and children—Apply one to three times a day to affected skin on the body, face, or scalp or as directed by the doctor.
  - For Brylcreem Antidandruff—Adults: Apply to scalp once a day after shampooing and toweling hair dry. Massage into scalp for one minute.
  - Children—Use and dose must be determined by the doctor.

For lotion dosage form:
- For dandruff and seborrheic dermatitis:
  - For DermaZinc Scalp: Adults—Apply to scalp one to three times a day or as directed by the doctor.
  - For DermaZinc Spray: Adults—Apply one spray to affected skin of body, face, or scalp one to three times a day or as directed by the doctor. Medicine should cover a three-inch-square area. Treatment should continue for one week after symptoms lessen.
  - For DermaZinc Baby: Children—Apply to affected skin of face, body, or scalp one to four times a day or as directed by the doctor.

For lotion shampoo dosage forms:
- For dandruff and seborrheic dermatitis:
  - Adults and children up to 2 years of age—Use once a day as a shampoo on the scalp at least two times a week; however, may be used every day. Apply to wet hair and leave on the scalp for several minutes or massage into scalp vigorously before rinsing.
  - Children up to 2 years of age—Use and dose must be determined by the doctor.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Zincon

If your condition does not get better after regular use of this medicine, or if it gets worse, check with your doctor.

Zincon Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Irritation of skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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zinc supplement (Oral route, Parenteral route)

30/06/10

Commonly used brand name(s):

In the U.S.

Galzin
M2 Zinc 50
Orazinc 110
Orazinc 220
Zinc-220
Zinc Chelated
Zn Plus Protein

In Canada

Prostavan

Available Dosage Forms:

Tablet
Capsule
Tablet, Extended Release

Uses For zinc supplement

Zinc supplements are used to prevent or treat zinc deficiency.

Zinc supplements may be used for other conditions as determined by your health care professional.

Lack of zinc may lead to poor night vision and wound-healing, a decrease in sense of taste and smell, a reduced ability to fight infections, and poor development of reproductive organs.

Acrodermatitis enteropathica (a lack of absorption of zinc from the intestine)
Alcoholism
Burns
Type 2 diabetes mellitus
Down’s syndrome
Eating disorders
Intestine diseases
Infections (continuing or chronic)
Kidney disease
Liver disease
Pancreas disease
Sickle cell disease
Skin disorders
Stomach removal
Stress (continuing)
Thalassemia
Trauma (prolonged)

In addition, premature infants may need additional zinc.

Increased need for zinc should be determined by your health care professional.

Claims that zinc is effective in preventing vision loss in the elderly have not been proven. Zinc has not been proven effective in the treatment of porphyria.

Injectable zinc is given by or under the supervision of a health care professional. Other forms of zinc are available without a prescription.

Wilson’s disease (a disease of too much copper in the body)

Importance of Diet

The daily amount of zinc needed is defined in several different ways.

For U.S.—
Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person’s age, sex, and physical condition (e.g., pregnancy).
Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

For Canada—
Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Normal daily recommended intakes in milligrams (mg) for zinc are generally defined as follows:

Persons	U.S. (mg)	Canada (mg)
Infants and children birth to 3 years of age	5–10	2–4
Children 4 to 6 years of age	10	5
Children 7 to 10 years of age	10	7–9
Adolescent and adult males	15	9–12
Adolescent and adult females	12	9
Pregnant females	15	15
Breast-feeding females	16–19	15

Before Using zinc supplement

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts.

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Amygdalin
Eltrombopag

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Proper Use of zinc supplement

Dosing

For oral dosage forms (capsules, lozenges, tablets, extended-release tablets):
- To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of zinc. The dosage form [e.g., zinc gluconate, zinc sulfate] has a different strength):
  - For the U.S
  - Adult and teenage males—15 milligrams (mg) per day.
  - Adult and teenage females—12 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—16 to 19 mg per day.
  - Children 4 to 10 years of age—10 mg per day.
  - Children birth to 3 years of age—5 to 10 mg per day.
  - For Canada
  - Adult and teenage males—9 to 12 mg per day.
  - Adult and teenage females—9 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—15 mg per day.
  - Children 7 to 10 years of age—7 to 9 mg per day.
  - Children 4 to 6 years of age—5 mg per day.
  - Children birth to 3 years of age—2 to 4 mg per day.
- To treat deficiency:
  - Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.

Missed Dose

If you miss a dose of zinc supplement, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using zinc supplement

Bran
Fiber-containing foods
Phosphorus-containing foods such as milk or poultry
Whole-grain breads and cereals

zinc supplement Side Effects

Along with its needed effects, a dietary supplement may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare – With large doses

Chills
continuing ulcers or sores in mouth or throat
fever
heartburn
indigestion
nausea
sore throat
unusual tiredness or weakness

Symptoms of overdose

Chest pain
dizziness
fainting
shortness of breath
vomiting
yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,Z

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Zinc Chelated

30/06/10

Generic Name: zinc supplement (Oral route, Parenteral route)

Commonly used brand name(s):

In the U.S.

Galzin
M2 Zinc 50
Orazinc 110
Orazinc 220
Zinc-220
Zinc Chelated
Zn Plus Protein

In Canada

Prostavan

Available Dosage Forms:

Tablet
Capsule
Tablet, Extended Release

Uses For Zinc Chelated

Zinc supplements are used to prevent or treat zinc deficiency.

Zinc supplements may be used for other conditions as determined by your health care professional.

Lack of zinc may lead to poor night vision and wound-healing, a decrease in sense of taste and smell, a reduced ability to fight infections, and poor development of reproductive organs.

Acrodermatitis enteropathica (a lack of absorption of zinc from the intestine)
Alcoholism
Burns
Type 2 diabetes mellitus
Down’s syndrome
Eating disorders
Intestine diseases
Infections (continuing or chronic)
Kidney disease
Liver disease
Pancreas disease
Sickle cell disease
Skin disorders
Stomach removal
Stress (continuing)
Thalassemia
Trauma (prolonged)

In addition, premature infants may need additional zinc.

Increased need for zinc should be determined by your health care professional.

Claims that zinc is effective in preventing vision loss in the elderly have not been proven. Zinc has not been proven effective in the treatment of porphyria.

Injectable zinc is given by or under the supervision of a health care professional. Other forms of zinc are available without a prescription.

Wilson’s disease (a disease of too much copper in the body)

Importance of Diet

The daily amount of zinc needed is defined in several different ways.

For U.S.—
Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person’s age, sex, and physical condition (e.g., pregnancy).
Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

For Canada—
Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Normal daily recommended intakes in milligrams (mg) for zinc are generally defined as follows:

Persons	U.S. (mg)	Canada (mg)
Infants and children birth to 3 years of age	5–10	2–4
Children 4 to 6 years of age	10	5
Children 7 to 10 years of age	10	7–9
Adolescent and adult males	15	9–12
Adolescent and adult females	12	9
Pregnant females	15	15
Breast-feeding females	16–19	15

Before Using Zinc Chelated

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts.

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Amygdalin
Eltrombopag

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Proper Use of zinc supplement

This section provides information on the proper use of a number of products that contain zinc supplement. It may not be specific to Zinc Chelated. Please read with care.

Dosing

For oral dosage forms (capsules, lozenges, tablets, extended-release tablets):
- To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of zinc. The dosage form [e.g., zinc gluconate, zinc sulfate] has a different strength):
  - For the U.S
  - Adult and teenage males—15 milligrams (mg) per day.
  - Adult and teenage females—12 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—16 to 19 mg per day.
  - Children 4 to 10 years of age—10 mg per day.
  - Children birth to 3 years of age—5 to 10 mg per day.
  - For Canada
  - Adult and teenage males—9 to 12 mg per day.
  - Adult and teenage females—9 mg per day.
  - Pregnant females—15 mg per day.
  - Breast-feeding females—15 mg per day.
  - Children 7 to 10 years of age—7 to 9 mg per day.
  - Children 4 to 6 years of age—5 mg per day.
  - Children birth to 3 years of age—2 to 4 mg per day.
- To treat deficiency:
  - Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.

Missed Dose

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Zinc Chelated

Bran
Fiber-containing foods
Phosphorus-containing foods such as milk or poultry
Whole-grain breads and cereals

Zinc Chelated Side Effects

Along with its needed effects, a dietary supplement may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare – With large doses

Chills
continuing ulcers or sores in mouth or throat
fever
heartburn
indigestion
nausea
sore throat
unusual tiredness or weakness

Symptoms of overdose

Chest pain
dizziness
fainting
shortness of breath
vomiting
yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,Z

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Zinacef

30/06/10

Generic Name: cefuroxime (Injection route, Intravenous route)

sef-ue-ROX-eem

Commonly used brand name(s):

In the U.S.

Zinacef

Available Dosage Forms:

Powder for Solution
Solution

Therapeutic Class: Antibiotic

Pharmacologic Class: 2nd Generation Cephalosporin

Uses For Zinacef

Cefuroxime is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth.

This medicine is available only with your doctor’s prescription.

Before Using Zinacef

Allergies

Pediatric

This medicine has been tested in children and, in effective doses, has not shown to cause different side effects or problems than it does in adults.

Geriatric

This medicine has been tested in the elderly and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of Zinacef

Dosing

For injection dosage form
- - Adults and teenagers—750 mg to 3 grams every six to eight hours usually for 5 to 14 days, injected into a muscle or vein. Gonorrhea is treated with a single dose of 1.5 grams, injected into a muscle; the total 1.5-gram dose is divided into two doses and injected into muscles at two separate places on the body, and given along with a single, oral 1-gram dose of probenecid.
  - Infants and children 1 month of age and older—12.5 to 150 mg per kg (5.68 to 68 mg per pound) of body weight every six to eight hours, injected into a muscle or vein.
  - Newborns—30 to 100 mg per kg (13.6 to 45.5 mg per pound) of body weight every eight to twelve hours, injected into a vein.

Missed Dose

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Consult your health care professional about how to store this medicine.

Precautions While Using Zinacef

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

Zinacef Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools
chest pain
chills
cough
fever
painful or difficult urination
shortness of breath
sore throat
sores, ulcers, or white spots on lips or in mouth
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness

Less common

Abdominal or stomach cramps
abdominal or stomach tenderness or pain
bloating
bluish color or changes in skin color
diarrhea, watery and severe, which may also be bloody
difficulty in breathing or swallowing, wheezing, shortness of breath
fast heartbeat
fever
hives or welts
increased thirst
muscle spasm or jerking of all extremities
nausea or vomiting
pain
skin itching, rash, or redness
sudden loss of consciousness
swelling of face, throat, or tongue
swelling of foot or leg
tenderness
unusual weight loss

Rare

Blistering, peeling, loosening of skin
bloody or cloudy urine
dizziness
fast heartbeat
greatly decreased frequency of urination or amount of urine
hearing loss, mild to moderate
joint or muscle pain
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
red or irritated eyes
redness, tenderness, itching, burning, or peeling of skin
red skin lesions, often with a purple center
sore throat
tightness in chest

More common

Gas
loss of appetite

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,Z

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zileuton (Oral route)

30/06/10

zye-LOO-ton

Commonly used brand name(s):

In the U.S.

Zyflo
Zyflo CR

Available Dosage Forms:

Tablet
Tablet, Extended Release

Therapeutic Class: Anti-Inflammatory

Pharmacologic Class: Leukotriene Pathway Inhibitor

Uses For zileuton

Zileuton is used by patients with mild-to-moderate chronic asthma to decrease the symptoms of asthma and the number of acute asthma attacks. However, zileuton should not be taken to relieve an asthma attack that has already started.

zileuton is available only with your doctor’s prescription.

Zileuton immediate-release tablets (Zyflo(R)) were withdrawn from the U. S. market by Critical Therapeutics on February 12, 2008. The extended-release formulation of zileuton (Zyflo CR(R)), also manufactured by Critical Therapeutics, Inc, is still available.

Before Using zileuton

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For zileuton, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to zileuton or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of zileuton in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zileuton in the elderly. However, elderly patients are more likely to have age-related liver disease, and zileuton should not be used in patients with this condition.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using zileuton with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Dihydroergotamine
Ergoloid Mesylates
Ergonovine
Ergotamine
Methylergonovine

Using zileuton with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Astemizole
Eltrombopag
Pimozide
Terfenadine
Theophylline
Tizanidine

Using zileuton with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Propranolol
Warfarin

Interactions with Food/Tobacco/Alcohol

Proper Use of zileuton

Zileuton is used to prevent asthma attacks. It is not used to relieve an attack that has already started. For relief of an asthma attack that has already started, you should use another inhaled medicine that works quickly. If you have any questions about this, check with your doctor.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

To work properly, zileuton must be taken every day at regularly spaced times, even if your asthma seems better.

Dosing

The dose of zileuton will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of zileuton. If your dose is different, do not change it unless your doctor tells you to do so.

For oral dosage form (extended-release tablets):
- For asthma prevention:
  - Adults and children 12 years of age and older—Two 600 milligram (mg) tablets two times a day, within one hour after morning and evening meals.
  - Children up to 12 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of zileuton, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using zileuton

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.

Check with your doctor if you are using more inhalations (puffs) than usual of your inhaled bronchodilator to relieve an acute asthma attack.

You may be taking other medicines for asthma along with zileuton. Do not stop taking or reduce the dose of the other medicines, even if your asthma seems better, unless you are told to do so by your doctor.

You should limit the amount of alcohol you drink while you are taking zileuton.

zileuton may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed and have problems with sleep. If you or your caregiver notice any of these side effects, tell your doctor right away.

zileuton Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Flu-like symptoms
itching
right upper stomach pain
unusual tiredness or weakness
yellow eyes or skin

Incidence not known

Attack, assault, or force
attempts at killing oneself
discouragement
dry mouth
fear or nervousness
feeling sad or empty
hyperventilation
irregular heartbeats
irritability
lack of appetite
loss of interest or pleasure
restlessness
seeing, hearing, or feeling things that are not there
shakiness in the legs, arms, hands, or feet
shortness of breath
sleeplessness
tiredness
trembling or shaking of the hands or feet
trouble with concentrating
trouble with sleeping
unable to sleep

More common

Cough
fever
headache
nausea
pain or tenderness around the eyes and cheekbones
stuffy or runny nose
tightness of the chest or wheezing
troubled breathing
upset stomach

Less common

Abdominal or stomach pain
sore throat
weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Zilactin

30/06/10

Generic Name: benzocaine (Oral route, Oromucosal route)

BEN-zoe-kane

Commonly used brand name(s):

In the U.S.

Anbesol
Babee Teething
Benzodent
Benz-O-Sthetic
Bi-Zets/Benzo-Troches
Dentemp’s
Dent-O-Kain/20
Detane
Gumsol
HAD
Hurricaine
Hurricane Spray Kit
Kank-A Soft Brush
Larynex
Miradyne-3
Mycinette
Orabase-B
Oracaine
Ora film
Orajel
OraMagic Plus
Orasol
Red Cross Canker Sore
Thorets
Trocaine
Zetts
Zilactin
Zilactin-B

In Canada

Anbesol Extra Strength
Anbesol Liquid
Baby Anbesol
Baby Orajel
Baby Orajel Liquid
Maximum Strength Orajel Pm
Orajel Extra Strength

Available Dosage Forms:

Liquid
Gel/Jelly
Solution
Lozenge/Troche
Lotion
Ointment
Powder for Suspension
Cream
Tablet, Disintegrating
Film
Swab
Spray
Gum
Paste

Therapeutic Class: Anesthetic, Local

Chemical Class: Amino Ester

Uses For Zilactin

Benzocaine lozenges are used to relieve pain and irritation caused by sore throat, sore mouth, or canker sores.

This medicine is available without a prescription; however, your doctor may have special instructions on the proper use and dose for your medical problem.

Before Using Zilactin

Allergies

Pediatric

No information is available on the relationship of age to the effects of benzocaine lozenges in the pediatric population. Safety and efficacy have not been established in children below 5 years of age.

Geriatric

No information is available on the relationship of age to the effects of benzocaine in geriatric patients.

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of benzocaine

This section provides information on the proper use of a number of products that contain benzocaine. It may not be specific to Zilactin. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of this medicine, do not use it more often, and do not use it for a longer time than directed. To do so may increase the chance of absorption into the body and the risk of side effects.

This medicine should be used only for problems being treated by your doctor or conditions listed in the package directions. Check with your doctor before using it for other problems, especially if you think that an infection may be present.

Do not use this medicine for more than 2 days without checking first with your doctor.

Dosing

For oral dosage form (lozenges):
- For sore throat and mouth pain:
  - Adults, teenagers, and children 5 years of age and older—One lozenge, dissolved slowly in the mouth every 2 hours as needed.
  - Children younger than 5 years of age—Use is not recommended.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Zilactin

If your condition does not improve within 7 days, or if it becomes worse, check with your doctor.

Call your doctor right away if you start to have a severe sore throat or sore throat that occurs with a high fever, headache, nausea, or vomiting. These maybe signs of an infection.

Zilactin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Headache
high fever
nausea
vomiting
worsening of pain, redness, swelling, or irritation in or around the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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zidovudine (Oral route)

30/06/10

zye-DOE-vue-deen

Intravenous routeSolution

Zidovudine has been associated with hematologic toxicity, including neutropenia and severe anemia, particularly in patients with advanced HIV disease. Prolonged use of zidovudine has been associated with symptomatic myopathy. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported .

Oral routeCapsuleTabletSyrup

Zidovudine has been associated with hematologic toxicity, including neutropenia and severe anemia, particularly in patients with advanced HIV disease.

Prolonged use of zidovudine has been associated with symptomatic myopathy.

Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including zidovudine and other antiretrovirals. Suspend treatment if clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity occur .

Commonly used brand name(s):

In the U.S.

Retrovir

Available Dosage Forms:

Capsule
Syrup
Tablet

Therapeutic Class: Antiretroviral Agent

Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor

Uses For zidovudine

Zidovudine (also known as AZT) is used in combination with other anti-virus medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Zidovudine is used to slow the progression of disease in patients infected with HIV who have advanced symptoms, early symptoms, or no symptoms at all. zidovudine also is used to help prevent pregnant women who have HIV from passing the virus to their babies during pregnancy and at birth.

Zidovudine will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems usually related to AIDS or HIV disease. Zidovudine will not keep you from spreading HIV to other people. People who receive zidovudine may continue to have the problems usually related to AIDS or HIV disease.

zidovudine is available only with your doctor’s prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, zidovudine is used in certain patients with the following medical condition:

Human immunodeficiency virus (HIV) infection due to occupational exposure (possible prevention of).

Before Using zidovudine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For zidovudine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to zidovudine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of zidovudine in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zidovudine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems which may require caution and an adjustment in the dose for patients receiving zidovudine.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using zidovudine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Dapsone
Doxorubicin Hydrochloride
Flucytosine
Ganciclovir
Interferon Alfa
Pyrazinamide
Pyrimethamine
Ribavirin
Stavudine
Vinblastine
Vincristine
Vincristine Liposome

Using zidovudine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acetaminophen
Interferon Beta-1a
Methadone
Nelfinavir
Probenecid
Rifabutin
Rifampin
Rifapentine
Tipranavir
Valproic Acid

Interactions with Food/Tobacco/Alcohol

Proper Use of zidovudine

Take zidovudine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking zidovudine without checking with your doctor first.

zidovudine comes with a patient information sheet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Keep taking zidovudine for the full time of treatment , even if you begin to feel better. Only take medicine that your doctor has prescribed specifically for you. Do not share your medicine with other people.

For patients using zidovudine oral solution:

Shake the oral solution before use. Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

zidovudine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. If you need help in planning the best times to take your medicine, check with your doctor.

Dosing

The dose of zidovudine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of zidovudine. If your dose is different, do not change it unless your doctor tells you to do so.

For HIV infection:
- For oral dosage forms (capsules, solution, and tablets):
  - Adults—600 milligrams (mg) a day in divided doses in combination with other anti-virus medicine.
  - Children and infants 4 weeks of age and older—Dose is based on body weight or body size and must be determined by your child’s doctor. The recommended dose is 18 to 24 milligrams (mg) per kilogram per day of body weight or 600 mg per day or 480 milligrams per square meter of body surface area (mg/m²) a day in divided doses.
To help prevent pregnant women from passing HIV to their babies during pregnancy and at birth:
- For oral dosage form (capsules):
  - Pregnant women (after 14 weeks of pregnancy, up to the start of labor)—100 milligrams (mg) five times a day, 200 mg every eight hours, or 300 mg every twelve hours until the start of labor.
- For oral dosage form (solution):
  - Pregnant women (after 14 weeks of pregnancy, up to the start of labor)—100 milligrams (mg) five times a day, 200 mg every eight hours, or 300 mg every twelve hours until the start of labor.
  - Newborn infants—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 mg per kilogram (kg) (0.9 mg per pound) of body weight every six hours starting within eight to twelve hours of birth and continuing through six weeks of age.

Missed Dose

If you miss a dose of zidovudine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using zidovudine

It is very important that your doctor check your or your child’s progress at regular visits to make sure that zidovudine is working properly. Blood tests may be needed to check for unwanted effects.

Zidovudine may cause blood problems. These problems may result in a greater chance of certain infections and slow healing. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks not to damage your gums. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.

Zidovudine may cause some serious side effects, including bone marrow problems. Symptoms of bone marrow problems include fever, chills, or sore throat; pale skin; and unusual tiredness or weakness. These problems may require blood transfusions or temporarily stopping treatment with zidovudine. Check with your doctor if any new health problems or symptoms occur while you or your child are taking zidovudine.

HIV may be acquired from or spread to other people through infected body fluids, including blood, vaginal fluid, or semen. If you are infected, it is best to avoid any sexual activity involving an exchange of body fluids with other people. If you do have sex, always wear (or have your partner wear) a condom (“rubber”). Only use condoms made of latex, and use them every time you have vaginal, anal, or oral sex. The use of a spermicide (such as nonoxynol-9) may also help prevent the spread of HIV if it is not irritating to the vagina, rectum, or mouth. Spermicides have been shown to kill HIV in lab tests. Do not use oil-based jelly, cold cream, baby oil, or shortening as a lubricant—these products can cause the condom to break. Lubricants without oil, such as K-Y Jelly, are recommended. Women may wish to carry their own condoms. Birth control pills and diaphragms will help protect against pregnancy, but they will not prevent someone from giving or getting the AIDS virus. If you inject drugs, get help to stop. Do not share needles with anyone. In some cities, more than half of the drug users are infected, and sharing even one needle can spread the virus. If you have any questions about this, check with your doctor.

Two rare but serious reactions to zidovudine are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver. These are more common if you are female, very overweight (obese), or have been taking anti-HIV medicines for a long time. Call your doctor right away if you or your child have more than one of these symptoms: abdominal discomfort or cramping; dark urine; decreased appetite; diarrhea; general feeling of discomfort; light-colored stools; muscle cramping or pain; nausea; unusual tiredness or weakness; trouble breathing; vomiting; or yellow eyes or skin.

When you or your child start taking HIV medicines, your immune system may get stronger. If you have infections that are hidden in your body (e.g., pneumonia or tuberculosis), you may notice new symptoms when your body tries to fight them. If this occurs, tell your doctor right away.

zidovudine may cause you or your child to have excess body fat. Tell your doctor right away if you notice changes in your body shape, including an increased amount of body fat in the neck or upper back, face, around the chest, or stomach area. You might also lose fat from your legs, arms, or face.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

zidovudine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fever, chills, or sore throat
pale skin
unusual tiredness or weakness

Rare

Abdominal or stomach discomfort
confusion
convulsions (seizures)
diarrhea
fast, shallow breathing
general feeling of discomfort
loss of appetite
mood or mental changes
muscle pain, tenderness, weakness, or cramping
nausea
shortness of breath
sleepiness

More common

Difficulty having a bowel movement (stool)
general feeling of discomfort or illness
headache (severe)
lack or loss of strength
muscle soreness
trouble with sleeping
vomiting
weight loss

Less common

Bluish-brown colored bands on nails
changes in skin color

Incidence not known

Acid or sour stomach
belching
burning, tingling, numbness or pain in the hands, arms, feet, or legs
heartburn
indigestion
muscle or bone pain
sensation of pins and needles, stabbing pain
stomach cramps
stomach pain
yellow eyes or skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Drugs & Medications:A-Z

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30/06/10

Uses For ziprasidone

Before Using ziprasidone

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of ziprasidone

Dosing

Missed Dose

Storage

Precautions While Using ziprasidone

ziprasidone Side Effects

30/06/10

Uses For ziprasidone

Before Using ziprasidone

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of ziprasidone

Precautions While Using ziprasidone

ziprasidone Side Effects

30/06/10

Uses For Zinx

Importance of Diet

Before Using Zinx

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of zinc supplement

Dosing

Missed Dose

Storage

Precautions While Using Zinx

Zinx Side Effects

30/06/10

Uses For Zincon

Before Using Zincon

Allergies

Pediatric

Geriatric

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of pyrithione

Dosing

Missed Dose

Storage

Precautions While Using Zincon

Zincon Side Effects

30/06/10

Uses For zinc supplement

Importance of Diet

Before Using zinc supplement

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of zinc supplement

Dosing