tye-kar-SIL-in dye-SOE-dee-um, KLAV-ue-la-nate poe-TAS-ee-um

Commonly used brand name(s):

In the U.S.

  • Timentin
  • Timentin Novaplus

Available Dosage Forms:

  • Powder for Solution
  • Solution

Therapeutic Class: Antibiotic

Pharmacologic Class: Ticarcillin

Uses For ticarcillin and clavulanate

Ticarcillin and clavulanate combination is used to treat bacterial infections in many different parts of the body.

Ticarcillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria or preventing their growth. However, ticarcillin and clavulanate will not work for colds, flu, or other virus infections.

ticarcillin and clavulanate is available only with your doctor’s prescription.


Before Using ticarcillin and clavulanate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ticarcillin and clavulanate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ticarcillin and clavulanate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in children. However, safety and efficacy have not been established in infants below 3 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in the elderly. However, elderly patients are more likely to have age-related kidney or heart problems, which may require an adjustment in the dose for patients receiving ticarcillin and clavulanate combination.

Pregnancy

Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of ticarcillin and clavulanate. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bleeding problems or
  • Congestive heart failure or
  • Diarrhea or
  • Heart disease or
  • Hypokalemia (low potassium in the blood)—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.




Proper Use of ticarcillin and clavulanate

A nurse or other trained health professional will give you ticarcillin and clavulanate. ticarcillin and clavulanate is given through a needle placed in one of your veins.


Precautions While Using ticarcillin and clavulanate

Your doctor will check your progress closely while you are receiving ticarcillin and clavulanate. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

ticarcillin and clavulanate may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have itching; hives; hoarseness; shortness of breath; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth after you receive ticarcillin and clavulanate.

Ticarcillin and clavulanate combination may cause diarrhea, and in some cases it can be severe. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you have any medical tests, tell the doctor in charge that you are taking ticarcillin and clavulanate. The results of some tests may be affected by ticarcillin and clavulanate.

Ticarcillin and clavulanate combination may decrease the effects of some oral contraceptives (birth control pills). To avoid an unwanted pregnancy, it is a good idea to use additional contraceptive measures with your pills (e.g. condoms, a diaphragm, or a contraceptive foam or jelly) while using ticarcillin and clavulanate.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

ticarcillin and clavulanate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

  • Blood in the urine
  • frequent urination
  • lower abdominal cramping
  • painful urination

Incidence not known

  • Abdominal or stomach cramps, pain, or tenderness
  • black, tarry stools
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • bloating
  • changes in skin color
  • chest pain or discomfort
  • chills
  • clay-colored stools
  • convulsions
  • cough
  • dark urine
  • diarrhea
  • diarrhea, watery and severe, which may also be bloody
  • dizziness
  • fast heartbeat
  • fever
  • general tiredness and weakness
  • headache
  • increased thirst
  • irritability
  • itching
  • joint or muscle pain
  • loss of appetite
  • lower back or side pain
  • muscle twitching
  • nausea or vomiting
  • pain, tenderness, or swelling of the foot or leg
  • pinpoint red spots on the skin
  • rash
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • restlessness
  • seizures
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling or inflammation of the mouth
  • swollen glands
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight loss
  • upper right abdominal pain
  • vomiting of blood
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • change in taste or bad unusual or unpleasant (after) taste
  • difficulty with moving
  • excess air or gas in the stomach or intestines
  • full feeling
  • heartburn
  • muscle aching, cramping, or stiffness
  • passing gas
  • swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

Tiamol

30/06/10

Generic Name: fluocinonide (Topical application route)

floo-oh-SIN-oh-nide

Commonly used brand name(s):

In the U.S.

  • Lidex
  • Lidex-E
  • Vanos

In Canada

  • Lidemol
  • Lidex Mild
  • Lidex Regular
  • Lyderm
  • Tcis
  • Tiamol
  • Topsyn
  • Trisyn

Available Dosage Forms:

  • Ointment
  • Emollient Cream
  • Cream
  • Solution
  • Gel/Jelly

Therapeutic Class: Corticosteroid, Strong

Pharmacologic Class: Adrenal Glucocorticoid

Uses For Tiamol

Fluocinonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor’s prescription.


Before Using Tiamol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluocinonide topical in the pediatric population. However, because of this medicine’s toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor’s instructions very carefully. For Vanos® cream, safety and efficacy have not been established in children younger than 12 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Vanos® cream in the elderly. However, elderly patients are more likely to have age-related medical problems, which may require caution in patients receiving Vanos® cream.

No information is available on the relationship of age to the effects of fluocinonide topical in geriatric patients.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Cushing’s syndrome (adrenal gland disorder) or
  • Diabetes or
  • Hyperglycemia (high blood sugar) or
  • Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.
  • Infection of the skin at or near the place of application or
  • Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.
  • Perioral dermatitis (skin problem) or
  • Rosacea (skin problem)—Vanos® cream should not be used in patients with these conditions.




Proper Use of fluocinonide

This section provides information on the proper use of a number of products that contain fluocinonide. It may not be specific to Tiamol. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

If you are using the Vanos® cream:

  • Do not use it on the face, groin, or underarms unless directed to do so by your doctor.
  • Do not use it for more than 2 weeks unless your doctor tells you otherwise.

To use:

  • Wash your hands with soap and water before and after using this medicine.
  • Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.
  • Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.
  • If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.
  • If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For topical dosage forms (cream, gel, ointment, or solution):
    • For redness, itching, and swelling of the skin:
      • Adults—Apply to the affected area of the skin two to four times per day.
      • Children—Apply to the affected area of the skin two to four times per day.
  • For topical dosage form (cream):
    • For atopic dermatitis:
      • Adults and children 12 years of age and older—Apply to the affected area of the skin once a day.
      • Children younger than 12 years of age—Use is not recommended.
    • For psoriasis:
      • Adults and children 12 years of age and older—Apply to the affected area of the skin one to two times per day.
      • Children younger than 12 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Tiamol

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child’s symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated areas.

Tiamol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

  • Blistering, burning, crusting, dryness, or flaking of the skin
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • redness and scaling around the mouth
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)
  • thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Fever
  • headache
  • muscle aches
  • sore throat
  • stuffy or runny nose
  • unusual tiredness or weakness

Incidence not known

  • Acne or pimples
  • burning and itching of the skin with pinhead-sized red blisters
  • burning, itching, and pain in hairy areas, or pus at the root of the hair
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of treated areas of dark skin
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

Ti-Seb

30/06/10

Generic Name: salicylic acid (Topical route)

sal-i-SIL-ik AS-id

Commonly used brand name(s):

In the U.S.

  • Akurza
  • Aliclen
  • Avosil
  • Betasal
  • Compound W
  • Corn Removing
  • Dermarest Psoriasis
  • DHS Sal
  • Drytex
  • Duofilm
  • Duoplant
  • Freezone
  • Fung-O
  • Gets-It Corn/Callus Remover
  • Gordofilm
  • Hydrisalic
  • Ionil
  • Ionil Plus
  • Keralyt
  • Keralyt Scalp
  • Lupicare
  • Mediplast
  • Mg217 Sal-Acid
  • Mosco Corn & Callus Remover
  • Neutrogena
  • Occlusal-HP
  • Off-Ezy
  • Oxy Balance
  • P & S
  • Palmer’s Skin Success Acne Cleanser
  • Propa pH
  • Salac
  • Sal-Acid Plaster
  • Salactic Film
  • Salex
  • Salitop
  • Salkera
  • Sal-Plant Gel
  • Salvax
  • Seba-Clear
  • Stri-Dex
  • Thera-Sal
  • Therasoft Anti-Acne
  • Tinamed
  • Ti-Seb
  • Wart-Off Maximum Strength
  • Zapzyt

In Canada

  • Acnex
  • Acnomel Acne Mask
  • Clear Away Wart Removal System
  • Compound W One-Step Wart Remover
  • Compound W Plus
  • Dr. Scholl’s Clear Away One Step Plantar Wart Remover
  • Dr. Scholl’s Cushlin Ultra Slim Callus Removers
  • Dr. Scholl’s Cushlin Ultra Slim Corn Removers
  • Duoforte 27
  • Freezone – One Step Callus Remover Pad
  • Freezone – One Step Corn Remover Pad

Available Dosage Forms:

  • Soap
  • Lotion
  • Liquid
  • Ointment
  • Foam
  • Gel/Jelly
  • Cream
  • Pad
  • Shampoo
  • Solution
  • Dressing
  • Stick

Therapeutic Class: Antiacne

Pharmacologic Class: NSAID

Chemical Class: Salicylate, Non-Aspirin

Uses For Ti-Seb

Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Some of these preparations are available only with your doctor’s prescription.


Before Using Ti-Seb

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acenocoumarol
  • Anisindione
  • Ardeparin
  • Certoparin
  • Dalteparin
  • Danaparoid
  • Dicumarol
  • Enoxaparin
  • Nadroparin
  • Parnaparin
  • Phenindione
  • Phenprocoumon
  • Probenecid
  • Reviparin
  • Tamarind
  • Tinzaparin
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blood vessel disease
  • Diabetes mellitus (sugar diabetes)—Use of this medicine may cause severe redness or ulceration, especially on the hands or feet
  • Inflammation, irritation, or infection of the skin—Use of this medicine may cause severe irritation if applied to inflamed, irritated, or infected area of the skin
  • Influenza (flu) or
  • Varicella (chicken pox)—This medicine should not be used in children and teenagers with the flu or chicken pox. There is a risk of Reye’s syndrome.
  • Kidney disease or
  • Liver disease—Using this medicine for a long time over large areas could result in unwanted effects




Proper Use of salicylic acid

This section provides information on the proper use of a number of products that contain salicylic acid. It may not be specific to Ti-Seb. Please read with care.

It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.

Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.

To use the cream, lotion, or ointment form of salicylic acid:

  • Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:

  • Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.
  • Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:

  • Wipe the pad over the affected areas.
  • Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:

  • This medicine comes with patient instructions. Read them carefully before using.
  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
  • Cut the plaster to fit the wart, corn, or callus and apply.
  • For corns and calluses:
    • Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
    • Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.
  • For warts:
    • Depending on the product, either:
      • Apply plaster and repeat every 48 hours as needed, or
        • Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.
    • Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.
  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:

  • Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:

  • Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.
  • If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:

  • Wet a cotton ball or pad with the topical solution and wipe the affected areas.
  • Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:

  • This medicine comes with patient instructions. Read them carefully before using.
  • This medicine is flammable. Do not use it near heat or open flame or while smoking.
  • Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
  • Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
  • Avoid breathing in the vapors from the medicine.
  • Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
  • Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.
  • For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.
  • For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
  • Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.
  • If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For cream dosage form:
    • For corns and calluses:
      • Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.
  • For gel dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 5% gel one time a day.
    • For psoriasis:
      • Adults and children—Use the 5% gel one time a day.
    • For common warts:
      • Adults and children—Use the 5 to 26% gel one time a day.
  • For lotion dosage form:
    • For acne:
      • Adults and children—Use the 1 to 2% lotion one to three times a day.
    • For dandruff and antiseborrhic dermatitis of the scalp:
      • Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.
  • For ointment dosage form:
    • For acne:
      • Adults and children—Use the 3 to 6% ointment as needed.
    • For psoriasis and seborrheic dermatitis:
      • Adults and children—Use the 3 to 10% ointment as needed.
    • For common warts:
      • Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.
  • For pads dosage form:
    • For acne:
      • Adults and children—Use one to three times a day.
  • For plaster dosage form:
    • For corns, calluses, common warts, or plantar warts:
      • Adults and children—Use one time a day or one time every other day.
  • For shampoo dosage form:
    • For dandruff or seborrheic dermatitis of the scalp:
      • Adults and children—Use on the scalp one or two times a week.
  • For soap dosage form:
    • For acne:
      • Adults and children—Use as needed.
  • For topical solution dosage form:
    • For acne:
      • Adults and children—Use the 0.5 to 2% topical solution one to three times a day.
    • For common warts and plantar warts:
      • Adults and children—Use the 5 to 27% topical solution one or two times a day.
    • For corns and calluses:
      • Adults and children—Use the 12 to 27% topical solution one or two times a day.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Ti-Seb

When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:

  • Abrasive soaps or cleansers
  • Alcohol-containing preparations
  • Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])
  • Cosmetics or soaps that dry the skin
  • Medicated cosmetics
  • Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.

Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.

Ti-Seb Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

  • Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known

  • Dryness and peeling of skin
  • flushing
  • redness of skin
  • unusually warm skin

Symptoms of salicylic acid poisoning

  • Confusion
  • diarrhea
  • dizziness
  • fast or deep breathing
  • headache (severe or continuing)
  • hearing loss
  • lightheadedness
  • nausea
  • rapid breathing
  • ringing or buzzing in ears (continuing)
  • severe drowsiness
  • stomach pain
  • vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Skin irritation not present before use of this medicine (mild)
  • stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

tye-AG-a-been

Commonly used brand name(s):

In the U.S.

  • Gabitril

Available Dosage Forms:

  • Tablet
  • Capsule

Therapeutic Class: Anticonvulsant

Pharmacologic Class: Gamma Aminobutyric Acid Uptake Inhibitor

Uses For tiagabine

Tiagabine is used to help control some types of seizures in the treatment of epilepsy. tiagabine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it.

Tiagabine is available only with your doctor’s prescription.


Before Using tiagabine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tiagabine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to tiagabine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of tiagabine in children younger than 12 years of age with use in other age groups, tiagabine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of tiagabine in the elderly with use in other age groups, tiagabine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using tiagabine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Carbamazepine
  • Fosphenytoin
  • Ginkgo
  • Phenobarbital
  • Phenytoin
  • Primidone

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of tiagabine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Liver problems—Higher blood levels of tiagabine may result, leading to an increase in the chance of side effects
  • Status epilepticus—Tiagabine may cause the condition to recur




Proper Use of tiagabine

Take tiagabine only as directed by your doctor, to help your condition as much as possible. Do not take more or less of it, and do not take it more or less often than your doctor ordered.

Tiagabine should be taken with food or on a full stomach.

Dosing

The dose of tiagabine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of tiagabine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For epilepsy:
      • Adults and teenagers 12 years of age and older—At first, 4 milligrams (mg) once a day. Your doctor may increase your dose slowly as needed and tolerated. However, the dose usually is not greater than 56 mg a day.
      • Children up to 12 years of age—Use and dose must be determined by the doctor.

Missed Dose

If you miss a dose of tiagabine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.


Precautions While Using tiagabine

Tiagabine may cause dizziness, drowsiness, trouble in thinking, trouble with motor skills, or vision problems. Make sure you know how you react to tiagabine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well.

tiagabine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; other medicines for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking tiagabine.

Do not stop taking tiagabine without first checking with your doctor. Stopping the medicine suddenly may cause your seizures to return or to occur more often. Your doctor may want you to gradually reduce the amount you are taking before stopping completely.

tiagabine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

  • Blue or purple spots on skin
  • difficulty in concentrating or paying attention

Less common

  • Burning, numbness, or tingling sensations
  • clumsiness or unsteadiness
  • confusion
  • itching
  • mental depression
  • speech or language problems

Rare

  • Agitation
  • bloody or cloudy urine
  • burning, pain, or difficulty in urinating
  • frequent urge to urinate
  • generalized weakness
  • hostility
  • memory problems
  • quick to react or overreact emotionally
  • rash
  • uncontrolled back-and-forth and/or rolling eye movements
  • walking in unusual manner

Symptoms of overdose

  • Agitation (severe)
  • clumsiness or unsteadiness (severe)
  • coma
  • confusion (severe)
  • drowsiness (severe)
  • increase in seizures
  • mental depression
  • severe muscle twitching or jerking
  • sluggishness
  • speech problems (severe)
  • weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Chills
  • diarrhea
  • dizziness
  • drowsiness
  • fever
  • headache
  • muscle aches or pain
  • nervousness
  • sore throat
  • tremor
  • unusual tiredness or weakness
  • vomiting

Less common

  • Abdominal pain
  • flushing
  • impaired vision
  • increased appetite
  • increased cough
  • mouth ulcers
  • muscle weakness
  • nausea
  • pain
  • trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

thye-roe-TROE-pin

Commonly used brand name(s):

In the U.S.

  • Thyrogen

In Canada

  • Thytropar

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Diagnostic Agent, Thyroid Function

Pharmacologic Class: Pituitary Hormone, Anterior

Uses For thyrotropin

Thyrotropin is used in a test to determine how well your thyroid is working. It may also be used for other conditions as determined by your doctor.

Thyrotropin is to be administered only by or under the immediate supervision of your doctor.


Before Using thyrotropin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For thyrotropin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to thyrotropin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

thyrotropin has been tested in children and has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in the elderly. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing the use of thyrotropin in the elderly with use in other age groups, thyrotropin is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of thyrotropin. Make sure you tell your doctor if you have any other medical problems, especially:

  • Hardening of the arteries or
  • Heart disease or
  • High blood pressure—Thyrotropin increases body metabolism and causes the heart to work harder, which may make these conditions worse
  • Untreated underactive adrenal gland or
  • Untreated underactive pituitary gland—Use of thyrotropin may severely worsen these conditions




Proper Use of thyrotropin

For your doctor to properly treat your medical condition, you must receive every dose of thyrotropin. After the last dose, the doctor may want to perform certain tests that are very important.

It is important that your doctor check your progress to make sure that thyrotropin is working properly and to check for unwanted effects.

Dosing

The dose of thyrotropin will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of thyrotropin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For testing the thyroid gland:
      • Adults and children—10 International Units (IU) injected under the skin or into a muscle once a day for one to three days. If thyroid testing is being done after surgery, thyrotropin will usually be given for three to seven days.

thyrotropin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Raremore common in patients who have received thyrotropin previously

  • Faintness
  • itching, redness, or swelling at place of injection
  • skin rash
  • tightness of throat
  • wheezing

Symptoms of overdose

  • Chest pain
  • fast or irregular heartbeat
  • irritability
  • nervousness
  • shortness of breath
  • sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Flushing of face
  • frequent urge to urinate
  • headache
  • nausea and vomiting
  • stomach discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

Thytropar

30/06/10

Generic Name: thyrotropin (Injection route)

thye-roe-TROE-pin

Commonly used brand name(s):

In the U.S.

  • Thyrogen

In Canada

  • Thytropar

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Diagnostic Agent, Thyroid Function

Pharmacologic Class: Pituitary Hormone, Anterior

Uses For Thytropar

Thyrotropin is used in a test to determine how well your thyroid is working. It may also be used for other conditions as determined by your doctor.

Thyrotropin is to be administered only by or under the immediate supervision of your doctor.


Before Using Thytropar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in the elderly. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing the use of thyrotropin in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Hardening of the arteries or
  • Heart disease or
  • High blood pressure—Thyrotropin increases body metabolism and causes the heart to work harder, which may make these conditions worse
  • Untreated underactive adrenal gland or
  • Untreated underactive pituitary gland—Use of thyrotropin may severely worsen these conditions




Proper Use of thyrotropin

This section provides information on the proper use of a number of products that contain thyrotropin. It may not be specific to Thytropar. Please read with care.

For your doctor to properly treat your medical condition, you must receive every dose of this medicine. After the last dose, the doctor may want to perform certain tests that are very important.

It is important that your doctor check your progress to make sure that this medicine is working properly and to check for unwanted effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For testing the thyroid gland:
      • Adults and children—10 International Units (IU) injected under the skin or into a muscle once a day for one to three days. If thyroid testing is being done after surgery, this medicine will usually be given for three to seven days.

Thytropar Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Raremore common in patients who have received thyrotropin previously

  • Faintness
  • itching, redness, or swelling at place of injection
  • skin rash
  • tightness of throat
  • wheezing

Symptoms of overdose

  • Chest pain
  • fast or irregular heartbeat
  • irritability
  • nervousness
  • shortness of breath
  • sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Flushing of face
  • frequent urge to urinate
  • headache
  • nausea and vomiting
  • stomach discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

ThyroShield

30/06/10

Generic Name: potassium iodide (Oral route)

poe-TAS-ee-um EYE-oh-dide

Oral routeSolution

  • Consumer packaging
    • Take potassium iodide (KI) only when public officials tell you. In a nuclear radiation emergency, radioactive iodine could be released into the air. KI protects only the thyroid gland from uptake of radioactive iodine. Therefore, KI should be used along with other emergency measures that will be recommended to you by public officials.
    • If you are told to take this medicine, take it one time every 24 hours. Do not take it more often. More KI will not help you. Too much KI may increase the chances of side effects. Do not take this medicine if you know you are allergic to iodine .

When used in a nuclear radiation emergency, instruct patients on the proper dosage and usage. Should be used along with other emergency measures that will be recommended by public officials .

Commonly used brand name(s):

In the U.S.

  • Pima
  • SSKI
  • ThyroShield

Available Dosage Forms:

  • Solution
  • Syrup

Therapeutic Class: Antithyroid Agent

Uses For ThyroShield

Potassium iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine. It may be used before and after administration of medicine containing radioactive iodine or after accidental exposure to radioactive iodine (for example, from nuclear power plant accidents that involved release of radioactivity to the environment). It may also be used for other problems as determined by your doctor.

Potassium iodide is taken by mouth. It may be taken as an oral solution, syrup, uncoated tablet, or enteric-coated delayed-release tablet. However, the delayed-release tablet form may cause serious side effects and its use is generally not recommended.

Some brands of the oral solution are available without a prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, potassium iodide is used in certain patients with the following medical conditions:

  • To prepare the thyroid gland before a thyroid operation
  • Iodine deficiency
  • Certain skin conditions caused by fungus

In addition to the above information, for patients taking this medicine for a fungus infection:

  • Keep taking it for the full course of treatment , even if you begin to feel better after a few days. This will help clear up your infection completely. Do not miss any doses .


Before Using ThyroShield

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Potassium iodide may cause skin rash and thyroid problems in infants.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of potassium iodide in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than in younger adults.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acenocoumarol
  • Anisindione
  • Dicumarol
  • Phenindione
  • Phenprocoumon
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • High blood levels of potassium (hyperkalemia) or
  • Myotonia congenita or
  • Tuberculosis—Potassium iodine may make these conditions worse
  • Kidney disease—May cause an increase of potassium in the blood
  • Overactive thyroid (unless you are taking this medicine for this medical problem)—Prolonged use of potassium iodine may be harmful to the thyroid gland




Proper Use of potassium iodide

This section provides information on the proper use of a number of products that contain potassium iodide. It may not be specific to ThyroShield. Please read with care.

If potassium iodide upsets your stomach, take it after meals or with food or milk unless otherwise directed by your doctor. If stomach upset (nausea, vomiting, stomach pain, or diarrhea) continues, check with your doctor.

For patients taking this medicine for radiation exposure :

  • Take this medicine only when directed to do so by state or local public health authorities.
  • Take this medicine once daily until the risk of significant exposure to radiation no longer exists.Do not take more of it and do not take it more often than directed. Taking more of the medicine will not protect you better and may result in a greater chance of side effects.

For patients taking the oral solution form of this medicine:

  • This medicine is to be taken by mouth even if it comes in a dropper bottle.
  • Do not use if solution turns brownish yellow.
  • Take potassium iodide in a full glass (8 ounces) of water or in fruit juice, milk, or broth to improve the taste and lessen stomach upset. Be sure to drink all of the liquid to get the full dose of medicine.
  • If crystals form in potassium iodide solution, they may be dissolved by warming the closed container of solution in warm water and then gently shaking the container.

For patients taking the uncoated tablet form of this medicine:

  • Before taking, dissolve each tablet in ½ glass (4 ounces) of water or milk. Be sure to drink all of the liquid to get the full dose of medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For solution dosage form:
    • To treat overactive thyroid (hyperthyroidism):
      • Adults and teenagers—250 milligrams (mg) (0.25 milliliters [mL]) three times a day.
      • Children—Use and dose must be determined by your doctor.
    • To protect the thyroid gland against radiation exposure:
      • Adults or teenagers approaching adult weight (greater than 70 kg or 154 lbs of body weight)—130 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children through 1 month of age—16 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children over 1 month through 3 years of age—32 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children and teenagers over 3 years through 18 years of age (less than 70 kg or 154 lbs of body weight) —65 mg once a day, until significant risk of exposure to radioiodines no longer exists.
  • For syrup dosage form:
    • To protect the thyroid gland against radiation exposure:
      • Adults or teenagers approaching adult weight (70 kg or 154 lbs of body weight) greater)—130 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children through 1 month of age—16 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children over 1 month through 3 years of age—32 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children and teenagers over 3 years through 18 years of age (less than 70 kg or 154 lbs of body weight)—65 mg once a day, until significant risk of exposure to radioiodines no longer exists.
  • For tablet dosage form:
    • To protect the thyroid gland against radiation exposure:
      • Adults or teenagers approaching adult weight (70 kg or 154 lbs of body weight)—130 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children through 1 month of age—16 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children over 1 month through 3 years of age—32 mg once a day, until significant risk of exposure to radioiodines no longer exists.
      • Children and teenagers over 3 years through 18 years of age (less than 70 kg or 154 lbs of body weight)—65 mg once a day, until significant risk of exposure to radioiodines no longer exists.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.


Precautions While Using ThyroShield

Your doctor should check your progress at regular visits to make sure that this medicine does not cause unwanted effects.

For patients on a low-potassium diet:

  • This medicine contains potassium. Check with your health care professional before you take this medicine.

ThyroShield Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

  • Hives
  • joint pain
  • swelling of arms, face, legs, lips, tongue, and/or throat
  • swelling of lymph glands

With long-term use

  • Burning of mouth or throat
  • confusion
  • headache (severe)
  • increased watering of mouth
  • irregular heartbeat
  • metallic taste
  • numbness, tingling, pain or weakness in hands or feet
  • soreness of teeth and gums
  • sores on skin
  • symptoms of head cold
  • unusual tiredness
  • weakness or heaviness of legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Diarrhea
  • nausea or vomiting
  • stomach pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

Thyrolar

30/06/10

Generic Name: liotrix (Oral route)

lee-voe-thye-ROX-een SOE-dee-um, lye-oh-THYE-roe-neen SOE-dee-um

Commonly used brand name(s):

In the U.S.

  • Euthroid
  • Thyrolar

Available Dosage Forms:

  • Tablet

Therapeutic Class: Thyroid Supplement

Uses For Thyrolar

Liotrix is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used to help decrease the size of enlarged thyroid glands (known as goiter) and to treat thyroid cancer .

Liotrix is also used in some medical tests to help diagnose problems with the thyroid gland .

This medicine is available only with your doctor’s prescription .


Before Using Thyrolar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of liotrix in children .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of liotrix in the elderly. However, elderly patients are more likely to have age-related heart and blood vessel problems, which may require caution in patients receiving liotrix .

Pregnancy

Pregnancy Category Explanation
All Trimesters A Adequate studies in pregnant women have not shown an increased risk of fetal abnormalities.

Breast Feeding

Levothyroxine

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Liothyronine

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acenocoumarol
  • Aluminum Carbonate, Basic
  • Aluminum Hydroxide
  • Aluminum Phosphate
  • Anisindione
  • Calcium Carbonate
  • Cholestyramine
  • Chromium
  • Colesevelam
  • Conjugated Estrogens
  • Dicumarol
  • Dihydroxyaluminum Aminoacetate
  • Dihydroxyaluminum Sodium Carbonate
  • Eltrombopag
  • Esterified Estrogens
  • Estradiol
  • Estriol
  • Estrone
  • Estropipate
  • Imatinib
  • Iron
  • Kelp
  • Lanthanum Carbonate
  • Lopinavir
  • Magaldrate
  • Magnesium Carbonate
  • Magnesium Hydroxide
  • Magnesium Oxide
  • Magnesium Trisilicate
  • Phenindione
  • Phenprocoumon
  • Phenytoin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • Sevelamer
  • Simvastatin
  • Sodium Polystyrene Sulfonate
  • Soybean
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Enteral Nutrition

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Adrenal insufficiency (untreated) or
  • Thyrotoxicosis (untreated, overactive thyroid)—This medicine should NOT be used in patients with any of these conditions .
  • Clotting disorder or
  • Diabetes or
  • Heart disease (history of) or
  • Other adrenal gland problems—Use with caution. Dosage adjustment may be needed .




Proper Use of liotrix

This section provides information on the proper use of a number of products that contain liotrix. It may not be specific to Thyrolar. Please read with care.

This medicine usually needs to be taken for the rest of your life. Do not stop taking this medicine or change your doses without first checking with your doctor. It may take several weeks before you start to notice an improvement in your symptoms .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablet):
    • For the treatment of hypothyroidism:
      • Adults—At first, one tablet of liotrix (Thyrolar-1/2) containing 6.25 microgram (mcg) of liothyronine and 25 mcg of levothyroxine once a day. Your doctor may increase your dose by one tablet of liotrix (Thyrolar-1/4) containing 3.1 mcg of liothyronine and 12.5 mcg of levothyroxine every 2 to 3 weeks. However, the dose is usually not more than one tablet of liotrix (Thyrolar-3) containing 37.5 mcg of liothyronine and 150 mcg of levothyroxine once a day.
      • Children—Follow dosing for the treatment of congenital hypothyroidism .
    • For the treatment of congenital hypothyroidism:
      • Children 0 to 6 months of age—At first, 3.1 mcg of liothyronine and 12.5 mcg of levothyroxine once a day. Doses may be increased as needed. However, the dose is usually not more than 6.25 mcg of liothyronine and 25 mcg of levothyroxine once a day.
      • Children 6 to 12 months of age—At first, 6.25 mcg of liothyronine and 25 mcg of levothyroxine once a day. Doses may be increased as needed. However, the dose is usually not more than 9.35 mcg of liothyronine and 37.5 mcg of levothyroxine once a day.
      • Children 1 to 5 years of age—At first, 9.35 mcg of liothyronine and 37.5 mcg of levothyroxine once a day. Doses may be increased as needed. However, the dose is usually not more than 12.5 mcg of liothyronine and 50 mcg of levothyroxine once a day.
      • Children 6 to 12 years of age—At first, 12.5 mcg of liothyronine and 50 mcg of levothyroxine once a day. Doses may be increased as needed. However, the dose is usually not more than 18.75 mcg of liothyronine and 75 mcg of levothyroxine once a day.
      • Children over 12 years of age—The usual dose is 18.75 mcg of liothyronine and 75 mcg of levothyroxine once a day. Doses may be increased as needed .

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store in the refrigerator. Do not freeze.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Thyrolar

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests will be needed to check for unwanted effects .

Liotrix should not be used for the treatment of obesity or for the purpose of losing weight. This medicine is ineffective for weight reduction and when taken in larger amount, it may cause more serious medical conditions .

Hypothyroidism can sometimes cause infertility in men and women. Liotrix should not be used for the treatment of infertility unless it is caused by hypothyroidism .

Call your doctor right away if you start to have chest pain, fast or irregular heartbeat, excessive sweating, heat intolerance, nervousness, or any other unusual medical condition .

For patients with diabetes, it is very important that you keep track of your blood or urine sugar levels as instructed by your doctor. Check with your doctor immediately if you notice any changes in your sugar levels .

A temporary loss of hair may occur during the first few months of liotrix therapy. Ask your doctor about this if you have any concerns .

Thyrolar Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not determined

  • Chest pain
  • constipation
  • depressed mood
  • difficulty in moving
  • discouragement
  • dryness of the eye
  • dry skin and hair
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fear, nervousness
  • feeling cold
  • feeling sad or empty
  • fever
  • headache
  • hives or welts
  • hoarseness or husky voice
  • increased sweating
  • increased weight
  • increase in blood pressure
  • irritability
  • irritation
  • itching skin
  • joint pain, stiffness or swelling
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle aching or cramping
  • muscle pain or stiffness
  • nausea
  • redness of skin
  • shakiness in legs, arms, hands, feet
  • shortness of breath
  • skin rash
  • sleeplessness
  • slowed heartbeat
  • sluggishness
  • swelling of eyelids, face, lips, hands, or feet
  • swollen joints
  • tightness in chest
  • tiredness
  • trembling or shaking of hands or feet
  • trouble concentrating
  • troubled breathing or swallowing
  • trouble sleeping
  • unable to sleep
  • unusual tiredness or weakness
  • weight gain
  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined

  • Hair loss, thinning of hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

THYE-roid

Oral routeTablet

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects .

In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects .

Commonly used brand name(s):

In the U.S.

  • Armour Thyroid
  • Nature-Throid NT-1
  • Nature-Throid NT-1/2
  • Nature-Throid NT-2
  • Nature-Throid NT-3
  • Nature-Thyroid
  • Westhroid

Available Dosage Forms:

  • Tablet
  • Capsule

Therapeutic Class: Thyroid Supplement

Uses For thyroid

Thyroid is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. It is also used to help decrease the size of enlarged thyroid glands (known as goiter) and to treat thyroid cancer .

Thyroid is also used in some medical tests to help diagnose problems with the thyroid gland .

thyroid is available only with your doctor’s prescription .


Before Using thyroid

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For thyroid, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to thyroid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of thyroid in children .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of thyroid in the elderly. However, elderly patients are more likely to have age-related heart and blood vessel problems, which may require caution in patients receiving thyroid .

Pregnancy

Pregnancy Category Explanation
All Trimesters A Adequate studies in pregnant women have not shown an increased risk of fetal abnormalities.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using thyroid with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acenocoumarol
  • Anisindione
  • Dicumarol
  • Kelp
  • Phenindione
  • Phenprocoumon
  • Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of thyroid. Make sure you tell your doctor if you have any other medical problems, especially:

  • Adrenal insufficiency (untreated) or
  • Thyrotoxicosis (overactive thyroid)—thyroid should NOT be used in patients with any of these conditions .
  • Adrenal insufficiency (history of) or
  • Clotting disorders or
  • Diabetes or
  • Heart disease—Use with caution. Dosage adjustment may be needed .




Proper Use of thyroid

thyroid usually needs to be taken for life. Do not stop taking thyroid or change your doses without first checking with your doctor. It may take several weeks before you start to notice an improvement in your symptoms .

Dosing

The dose of thyroid will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of thyroid. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablet):
    • For the treatment of hypothyroidism:
      • Adults—At first, 30 milligrams (mg) once a day. Then, your doctor may increase your dose a little at a time up to the usual maintenance dose of 60 to 120 mg a day. A lower starting dose of 15 mg/day may be given to patients for certain conditions.
      • Children 0 to 6 months of age—The dose is based on body weight and must be determined by your doctor. The usual dose is 15 to 30 mg once a day.
      • Children 6 to 12 months of age—The dose is based on body weight and must be determined by your doctor. The usual dose is 30 to 45 mg once a day.
      • Children 1 to 5 years of age—The dose is based on body weight and must be determined by your doctor. The usual dose is 45 to 60 mg once a day.
      • Children 6 to 12 years of age—The dose is based on body weight and must be determined by your doctor. The usual dose is 60 to 90 mg once a day.
      • Children over 12 years of age—The dose is based on body weight and must be determined by your doctor. The usual dose is over 90 mg once a day .

Missed Dose

If you miss a dose of thyroid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

DRUG: GENERAL, STORAGE DRUG: GENERAL, STORAGE

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.


Precautions While Using thyroid

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood and urine tests will be needed to check for unwanted effects .

Thyroid should not be used for the treatment of obesity or for the purpose of losing weight. thyroid is ineffective for weight reduction and when taken in larger amount, it may cause more serious medical conditions .

Hypothyroidism can sometimes cause infertility in men and women. Thyroid should not be used for the treatment of infertility unless it is caused by hypothyroidism .

Call your doctor right away if you start to have chest pain, fast, irregular, pounding, or racing heartbeat or pulse, excessive sweating, heat intolerance, nervousness, or any other unusual medical condition .

For patients with diabetes, it is very important that you keep track of your blood or urine sugar levels as instructed by your doctor. Check with your doctor immediately if you notice any changes in your sugar levels .

A temporary loss of hair may occur during the first few months of thyroid therapy. Ask your doctor about this if you have any concerns .

thyroid Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Get emergency help immediately if any of the following symptoms of overdose occur:

  • Changes in appetite
  • changes in menstrual periods
  • chest pain
  • diarrhea
  • fast or irregular heartbeat
  • fever
  • hand tremors
  • headache
  • irritability
  • leg cramps
  • nervousness
  • sensitivity to heat
  • shortness of breath
  • sweating
  • trouble sleeping
  • vomiting
  • weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

 

Thymoglobulin

30/06/10

Generic Name: antithymocyte globulin rabbit (Intravenous route)

an-tye-THYE-moe-site GLOB-yoo-lin RAB-it

Intravenous routePowder for Solution

Antithymocyte globulin rabbit should only be used by physicians experienced in immunosuppressive therapy for the management of renal transplant patients .

Should only be used by physicians experienced in immunosuppressive therapy for the management of renal transplant patients .

Commonly used brand name(s):

In the U.S.

  • Thymoglobulin

Available Dosage Forms:

  • Powder for Solution

Therapeutic Class: Immune Suppressant

Uses For Thymoglobulin

Anti-thymocyte globulin (rabbit) is an immunosuppressant. It is used to reduce the body’s natural immunity in patients who receive kidney transplants.

When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ. Anti-thymocyte globulin (rabbit) works by preventing the white blood cells from doing this.

The effect of anti-thymocyte globulin (rabbit) on the white blood cells may also reduce the body’s ability to fight infections. Before you begin treatment, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

Anti-thymocyte globulin (rabbit) is to be administered only by or under the immediate supervision of your doctor.


Before Using Thymoglobulin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of anti-thymocyte globulin (rabbit) in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of anti-thymocyte globulin (rabbit) in the elderly with use in other age groups.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergic to rabbit protein (history of)—Risk of serious allergic reaction, bleeding, and infection.
  • Infection—Anti-thymocyte globulin (rabbit) decreases your body’s ability to fight infection.




Proper Use of Thymoglobulin

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • To treat kidney transplant rejection:
      • Adults—1.5 milligrams for every kilogram (2.2 pounds) of your body weight injected into a vein every day for 7 to 14 days.
      • Children—Use and dose must be determined by your doctor.


Precautions While Using Thymoglobulin

Treatment with anti-thymocyte globulin (rabbit) may also increase the chance of getting other infections. If you can, avoid people with colds or other infections. If you think you are getting a cold or other infection, check with your doctor.

This medicine commonly causes fever and chills within a few hours after the first dose. These effects should be less after the second dose. However, check with your doctor or nurse immediately if you have chest pain, rapid or irregular heartbeat, shortness of breath or wheezing, or swelling of the face or throat after any dose.

Thymoglobulin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Because of the way that anti-thymocyte globulin (rabbit) acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas and skin cancers. Discuss these possible effects with your doctor.

Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

  • Black, tarry stools
  • bladder pain
  • chest pain
  • chills
  • cloudy or bloody urine
  • cold
  • confusion
  • cough or hoarseness
  • fast heartbeat
  • fever
  • flu-like symptoms
  • frequent urge to urinate
  • high blood pressure
  • irregular or slow heartbeat
  • lower back or side pain
  • numbness or tingling around lips hands, or feet
  • painful or difficult urination
  • shortness of breath or troubled breathing
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • swollen glands
  • tiredness or weakness
  • unexplained anxiety
  • unusual bleeding or bruising
  • weakness or heaviness of legs

Less common

  • Burning or stinging of skin
  • painful cold sores or blisters on lips, nose, eyes, or genitals

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Abdominal pain
  • diarrhea
  • difficult or labored breathing
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • loss of strength or energy
  • muscle pain or weakness
  • nausea
  • pain
  • swelling of ankles, feet, and fingers
  • tightness in chest
  • unusual weak feeling
  • wheezing

Less common

  • White patches on mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.