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brompheniramine, dextromethorphan, guaifenesin, and
pseudoephedrine

Generic Name: brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine (brom fen EER a meen, dex tro me THOR fan, gwye FEN e sin, soo doe e FED rin)
Brand names: Bromhist-DM, Histacol DM Pediatric Syrup, Pediahist DM Syrup, Uni-Hist DM Pediatric Syrup, AccuHist DM Pediatric Syrup

What is brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine is used to treat sneezing, runny or stuffy nose, cough, chest congestion, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, expectorant, or cough suppressant. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

What should I discuss with my healthcare provider before taking brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Before taking this medication, tell your doctor if you are allergic to brompheniramine, or pseudoephedrine, or if you have:

kidney disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
emphysema or chronic bronchitis;
an enlarged prostate; or
problems with urination.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine. Tell your doctor if you regularly use any of these medicines, or any other cold medicines.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, expectorant, or cough suppressant.

Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeat;
slow, shallow breathing;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
urinating less than usual or not at all.

Less serious side effects may include:

dry mouth;
nausea, stomach pain, constipation, mild loss of appetite, upset stomach;
blurred vision;
warmth, tingling, or redness under your skin;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness, or headache;
problems with memory or concentration; or
ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine?

Tell your doctor about all other medications you use, especially:

a diuretic (water pill), or blood pressure medicine;
medication to treat irritable bowel syndrome;
bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), darifenacin (Enablex), or tolterodine (Detrol);
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or
antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

This list is not complete and there may be other drugs that can interact with brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

B,Concise

Comments (0)

brompheniramine, dextromethorphan, guaifenesin, phenylephrine

30/06/10

Generic Name: brompheniramine, dextromethorphan, guaifenesin, phenylephrine (brom fen EER a meen, dex tro me THOR fan, gwye FEN e sin, fen il EFF rin)
Brand names: Allanhist PDX Syrup, Bromhist-PDX, AccuHist PDX Syrup, Uni-Hist PDX Syrup, EndaCof-PD

What is brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dextromethorphan, guaifenesin, and phenylephrine is used to treat sneezing, runny or stuffy nose, cough, chest congestion, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Brompheniramine, dextromethorphan, guaifenesin, and phenylephrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, expectorant, or cough suppressant. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Brompheniramine, dextromethorphan, guaifenesin, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

What should I discuss with my healthcare provider before taking brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Before taking this medication, tell your doctor if you are allergic to brompheniramine, or phenylephrine, or if you have:

kidney disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
emphysema or chronic bronchitis;
an enlarged prostate; or
problems with urination.

If you have any of these conditions, you may not be able to use brompheniramine, dextromethorphan, guaifenesin, and phenylephrine, or you may need a dosage adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Brompheniramine, dextromethorphan, guaifenesin, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an overdose may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Avoid using other medicines that make you sleepy (such as sleeping pills, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by brompheniramine, dextromethorphan, guaifenesin, and phenylephrine.

Brompheniramine, dextromethorphan, guaifenesin, and phenylephrine side effects

fast, pounding, or uneven heartbeat;
slow, shallow breathing;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
urinating less than usual or not at all.

Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

dry mouth;
nausea, stomach pain, constipation, mild loss of appetite, upset stomach;
blurred vision;
warmth, tingling, or redness under your skin;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness, or headache;
problems with memory or concentration; or
ringing in your ears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Brompheniramine, dextromethorphan, guaifenesin, phenylephrine Dosing Information

Usual Adult Dose for Cough and Nasal Congestion:

Brompheniramine 2 mg/DM 5 mg/guaifenesin 50 mg/phenylephrine 5 mg/5 mL:
5 to 10 mL orally every 4 to 6 hours not to exceed 6 doses per day.

Usual Pediatric Dose for Cough and Nasal Congestion:

Brompheniramine 2 mg/DM 5 mg/guaifenesin 50 mg/phenylephrine 5 mg/5 mL:
>= 12 yrs: 5 to 10 mL orally every 4 to 6 hours not to exceed 6 doses per day.
>= 6 yrs to <12 yrs: 2.5 to 5 mL orally every 4 to 6 hours not to exceed 6 doses per day.
>= 2 yrs to <6 yrs: 1.25 to 2.5 mL orally every 4 to 6 hours not to exceed 6 doses per day.

What other drugs will affect brompheniramine, dextromethorphan, guaifenesin, and phenylephrine?

Before taking this medication, tell your doctor if you are using any of the following drugs:

a diuretic (water pill), or blood pressure medicine;
medication to treat irritable bowel syndrome;
bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), darifenacin (Enablex), or tolterodine (Detrol);
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or
antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

If you are using any of these drugs, you may not be able to use brompheniramine, dextromethorphan, guaifenesin, and phenylephrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect brompheniramine, dextromethorphan, guaifenesin, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about brompheniramine, dextromethorphan, guaifenesin, and phenylephrine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

B,Concise

Comments (0)

brompheniramine, dihydrocodeine, and phenylephrine

30/06/10

Generic Name: brompheniramine, dihydrocodeine, and phenylephrine (BROM fen IR a meen, dye HYE dro KOE deen, FEN il EFF rin)
Brand names: Poly-Tussin DHC, EndaCof-DH

What is brompheniramine, dihydrocodeine, and phenylephrine?

Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dihydrocodeine is a narcotic cough suppressant.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dihydrocodeine, and phenylephrine is used to treat nasal congestion, sneezing, runny nose, and cough caused by the common cold.

Dihydrocodeine will not treat a cough that is caused by smoking, asthma, or emphysema.

Brompheniramine, dihydrocodeine, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about brompheniramine, dihydrocodeine, and phenylephrine?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough and cold medicine before the MAO inhibitor has cleared from your body. You should not use brompheniramine, dihydrocodeine, and phenylephrine if you are allergic to it, or if you have peptic ulcer, severe or uncontrolled high blood pressure, severe coronary artery disease, ischemic heart disease (reduced circulation of blood to the heart), narrow-angle glaucoma, if you are breast-feeding a baby, or if you are unable to urinate.

Before taking this medication, tell your doctor if you have heart disease or high blood pressure, asthma or other breathing disorder, diabetes, a thyroid disorder, glaucoma, kidney or liver disease, gallbladder disease, pancreatitis, Addison’s disease or other adrenal gland disorder, a seizure disorder, head injury or brain tumor, an enlarged prostate, problems with urination, mental illness, or a history of drug or alcohol addiction.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Brompheniramine, dihydrocodeine, and phenylephrine should not be given to a child younger than 6 years old.

What should I discuss with my healthcare provider before taking brompheniramine, dihydrocodeine, and phenylephrine?

Do not use this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough and cold medicine before the MAO inhibitor has cleared from your body. You should also not take codeine if you are having an asthma attack or if you have a bowel obstruction called paralytic ileus. You should not use brompheniramine, dihydrocodeine, or phenylephrine, if you have ever had an allergic reaction to it, or if you have:

severe or uncontrolled high blood pressure;
severe coronary artery disease;
narrow-angle glaucoma;
peptic ulcer;
if you are unable to urinate;
if you are pregnant;
if you are having an asthma attack.

If you have certain conditions, you may need a dose adjustment or special tests to safely take brompheniramine, dihydrocodeine, and phenylephrine. Before taking this medication, tell your doctor if you have:

heart disease or high blood pressure;
ischemic heart disease (reduced circulation of blood to the heart);
asthma, COPD, or other breathing disorder;
glaucoma;
diabetes;
kidney or liver disease;
a thyroid disorder;
enlarged prostate, urination problems;
gallbladder disease or pancreatitis;
Addison’s disease or other adrenal gland disorders;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
mental illness; or
a history of drug or alcohol addiction.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Dihydrocodeine may cause breathing problems or addiction/withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant while you are taking this medication. This medication can pass into breast milk and may harm a nursing baby. The use of dihydrocodeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more sensitive to the side effects of this medication. Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

How should I take brompheniramine, dihydrocodeine, and phenylephrine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cold medicine is usually taken for only a short time until your symptoms clear up.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash. Store brompheniramine, dihydrocodeine, and phenylephrine at room temperature away from moisture and heat.

Keep track of how much of this medicine has been used from the bottle. Dihydrocodeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Since cough and cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of dihydrocodeine can be fatal.

Overdose symptoms may include extreme drowsiness, pinpoint pupils, cold and clammy skin, limp muscles, fainting, seizure (convulsions), shallow breathing or breathing that stops.

What should I avoid while taking brompheniramine, dihydrocodeine, and phenylephrine?

Tell your doctor if you regularly use other medicines that make you sleepy (such as pain medication, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by brompheniramine, dihydrocodeine, and phenylephrine.

Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Brompheniramine or phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains brompheniramine or phenylephrine.

Brompheniramine, dihydrocodeine, and phenylephrine side effects

fast or pounding heartbeat;
feeling like you might pass out;
weak or shallow breathing;
confusion, hallucinations;
severe dizziness, anxiety, restless feeling, or nervousness;
seizure (convulsions); or
painful or difficult urination.

Less serious side effects may include:

dizziness, drowsiness, headache, tired feeling;
feeling excited or restless;
increased dreaming;
increased sweating or urination;
nausea, vomiting, diarrhea, constipation, loss of appetite;
dry mouth;
blurred vision, dry eyes; or
mild skin rash or itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Brompheniramine, dihydrocodeine, and phenylephrine Dosing Information

Usual Adult Dose for Cough and Nasal Congestion:

Brompheniramine/dihydrocodeine/phenylephrine 4 mg-3 mg-7.5 mg/5 mL oral liquid:
5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Brompheniramine/dihydrocodeine/phenylephrine 4 mg-3 mg-7.5 mg/5 mL oral liquid:
6 to 11 years: 2.5 mL orally every 4 to 6 hours not to exceed 15 mL daily.
12 years or older: 5 mL orally every 4 to 6 hours not to exceed 30 mL daily.

What other drugs will affect brompheniramine, dihydrocodeine, and phenylephrine?

Tell your doctor about all other medicines you use, especially:

methyldopa (Aldomet);
mecamylamine (Inversine);
reserpine;
promethazine (Phenergan, Adgan, Anergan 50, Pentazine);
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or
an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

This list is not complete and there may be other drugs that can interact with brompheniramine, dihydrocodeine, and phenylephrine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about brompheniramine, dihydrocodeine, and phenylephrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

B,Concise

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brompheniramine, dihydrocodeine, and pseudoephedrine

30/06/10

Generic Name: brompheniramine, dihydrocodeine, and pseudoephedrine (BROM fen IR a meen, dye HYE droe KOE deen, SOO doe ee FED rin)
Brand Names: J-Cof DHC

What is brompheniramine, dihydrocodeine, and pseudoephedrine?

Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dihydrocodeine is in a group of drugs called narcotics and is similar to codeine. Dihydrocodeine is a cough suppressant that affects signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, dihydrocodeine, and pseudoephedrine is used to treat cough, sneezing, itching, watery eyes, runny nose, stuffy nose, and sinus congestion caused by allergies, the common cold, or the flu.

Brompheniramine, dihydrocodeine, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about brompheniramine, dihydrocodeine, and pseudoephedrine?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. Dihydrocodeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Dihydrocodeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription. Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my healthcare provider before taking brompheniramine, dihydrocodeine, and pseudoephedrine?

Before taking brompheniramine, dihydrocodeine, and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

kidney or liver disease;
heart disease or high blood pressure;
enlarged prostate or urination problems;
diabetes;
glaucoma;
a thyroid disorder;
asthma, COPD, sleep apnea, or other breathing disorders;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
low blood pressure;
gallbladder disease;
Addison’s disease or other adrenal gland disorders;
mental illness; or
a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Dihydrocodeine may be habit-forming and should be used only by the person it was prescribed for. Dihydrocodeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Dihydrocodeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

How should I take brompheniramine, dihydrocodeine, and pseudoephedrine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cough or cold medicine is usually taken for only a short time until your symptoms clear up.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of dihydrocodeine can be fatal. Overdose symptoms may include extreme dizziness or drowsiness, confusion, feeling restless or nervous, cold and clammy skin, warmth or tingly feeling, nausea, vomiting, slow or shallow breathing, slow heart rate, pinpoint pupils, fainting, and seizure (convulsions).

What should I avoid while taking brompheniramine, dihydrocodeine, and pseudoephedrine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Do not drink alcohol while you are taking this medication. Alcohol can increase some of the side effects of brompheniramine, dihydrocodeine, and pseudoephedrine.

Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. Brompheniramine and pseudoephedrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Brompheniramine, dihydrocodeine, and pseudoephedrine side effects

fast, pounding, or uneven heartbeats;
shallow breathing, slow heartbeat;
severe dizziness, fainting, anxiety, restless feeling, nervousness, or tremor;
confusion, hallucinations, unusual thoughts or behavior;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;
urinating less than usual or not at all; or
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

Less serious side effects may include:

blurred vision;
dry mouth;
nausea, vomiting, stomach pain, constipation, mild loss of appetite;
mild dizziness, drowsiness;
problems with memory or concentration;
ringing in your ears;
warmth, tingling, or redness under your skin;
restless or excitability (especially in children);
sleep problems (insomnia); or
skin rash or itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Brompheniramine, dihydrocodeine, and pseudoephedrine Dosing Information

Usual Adult Dose for Cough and Nasal Congestion:

Brompheniramine/dihydrocodeine/PSE 3 mg-7.5 mg-15 mg/5 mL oral liquid:
5 to 10 mL orally every 4 to 6 hours.

Usual Pediatric Dose for Cough and Nasal Congestion:

Brompheniramine/dihydrocodeine/PSE 3 mg-7.5 mg-15 mg/5 mL oral liquid:
6 to 11 years: 2.5 mL to 5 mL orally every 4 to 6 hours.
12 years or older: 5 to 10 mL orally every 4 to 6 hours.

What other drugs will affect brompheniramine, dihydrocodeine, and pseudoephedrine?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by brompheniramine or dihydrocodine.

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others; or
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others;

This list is not complete and there may be other drugs that can interact with brompheniramine, dihydrocodeine, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about brompheniramine, dihydrocodeine, and pseudoephedrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

B,Concise

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brompheniramine/carbetapentane/phenylephrine

30/06/10

Generic Name: brompheniramine/carbetapentane/phenylephrine (brome fen IR a meen, kar be ta PEN tane, fen il EF rin)
Brand names: BetaTan, Pulmari, VazoTan, Seradex, V-Cof

What is brompheniramine, carbetapentane and phenylephrine?

Carbetapentane is a cough suppressant.

Brompheniramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Histamine can produce allergy symptoms such as sneezing, runny nose, and watery eyes.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of brompheniramine, carbetapentane and phenylephrine is used to treat cough and nasal congestion associated with allergies or the common cold.

Brompheniramine, carbetapentane and phenylephrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about brompheniramine, carbetapentane and phenylephrine?

Do not use brompheniramine, carbetapentane and phenylephrine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take brompheniramine, carbetapentane and phenylephrine before the MAO inhibitor has cleared from your body. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of brompheniramine, carbetapentane and phenylephrine. Do not use any other over-the-counter cough, cold, or allergy medications without first asking your doctor or pharmacist. Brompheniramine or phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains brompheniramine, carbetapentane, or phenylephrine.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by brompheniramine, carbetapentane, and phenylephrine.

What should I discuss with my healthcare provider before taking brompheniramine, carbetapentane and phenylephrine?

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

a history of head injury or seizure disorder;
sleep apnea (periods of not breathing during sleep);
thyroid problems;
asthma, emphysema, or chronic obstructive pulmonary disease (COPD);
gallbladder disease;
Addison’s disease;
diabetes;
glaucoma;
an ulcer or an obstruction in the stomach;
bladder problems or difficulty urinating;
an enlarged prostate;
high blood pressure, irregular heartbeats, or any type of heart disease;
kidney disease; or
liver disease.

If you have any of these conditions, you may not be able to use brompheniramine, carbetapentane, and phenylephrine, or you may need a dosage adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Brompheniramine, carbetapentane and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

How should I take brompheniramine, carbetapentane and phenylephrine?

Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your symptoms do not improve, if they get worse, or if you develop a fever.

Store this medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a brompheniramine, carbetapentane and phenylephrine overdose may include dry mouth, large pupils, warmth or tingling under the skin, nausea, vomiting, restless feeling, or hallucinations.

What should I avoid while taking brompheniramine, carbetapentane and phenylephrine?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of brompheniramine, carbetapentane and phenylephrine. Do not use any other over-the-counter cough, cold, or allergy medications without first asking your doctor or pharmacist. Brompheniramine or phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains brompheniramine, carbetapentane, or phenylephrine.

Brompheniramine, carbetapentane and phenylephrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects are more likely to occur with this medication, such as:

dryness of the eyes, nose, or mouth;
drowsiness or dizziness;
blurred vision;
difficulty urinating; or
excitation (in children).

Brompheniramine/carbetapentane/phenylephrine Dosing Information

Usual Adult Dose for Allergic Rhinitis:

brompheniramine/carbetapentane/phenylephrine 4 mg-30 mg-7.5 mg/5 mL or brompheniramine/carbetapentane/phenylephrine 6 mg-25 mg-10 mg/5 mL oral suspension: 5 to 10 mL orally every 12 hours.
brompheniramine/carbetapentane/phenylephrine 6 mg-30 mg-10 mg/5 mL oral suspension: 5 mL orally every 6 hours. Not to exceed 4 doses in 24 hours.

Usual Adult Dose for Cold Symptoms:

Usual Adult Dose for Cough and Nasal Congestion:

Usual Pediatric Dose for Allergic Rhinitis:

brompheniramine/carbetapentane/phenylephrine 4 mg-30 mg-7.5 mg/5 mL oral suspension:
12 yrs or older: 5 to 10 mL orally every 12 hours.
6 yrs to 11 yrs: 2.5 to 5 mL orally every 12 hours.
2 yrs to 5 yrs: 1.25 to 2.5 mL orally every 12 hours.

brompheniramine/carbetapentane/phenylephrine 6 mg-25 mg-10 mg/5 mL oral suspension:
12 yrs or older: 5 to 10 mL orally every 12 hours.
6 yrs to 11 yrs: 5 mL orally every 12 hours.
2 yrs to 5 yrs: 2.5 mL orally every 12 hours.

brompheniramine/carbetapentane/phenylephrine 6 mg-30 mg-10 mg/5 mL oral suspension:
12 yrs or older: 5 mL orally every 6 hours. Not to exceed 4 doses in 24 hours.
6 yrs to 11 yrs: 2.5 mL orally every 6 hours. Not to exceed 4 doses in 24 hours.

Usual Pediatric Dose for Cold Symptoms:

Usual Pediatric Dose for Cough and Nasal Congestion:

What other drugs will affect brompheniramine, carbetapentane and phenylephrine?

There may be other drugs not listed that can affect brompheniramine, carbetapentane, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about brompheniramine, carbetapentane and phenylephrine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

B,Concise

Comments (0)

30/06/10

Brompheniramine/

Carbetapentane/

Phenylephrine Suspension

Generic Name: Brompheniramine/Carbetapentane/Phenylephrine (BROME-fen-IR-a-meen/KAR-bay-ta-PEN-tane/FEN-il-EF-rin)
Brand Name: Examples include V-Cof and Vazotan

Brompheniramine/Carbetapentane/Phenylephrine Suspension is used for:

Relieving symptoms of sinus congestion, pressure, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Brompheniramine/Carbetapentane/Phenylephrine Suspension is an antihistamine, decongestant, and cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, which relieves congestion and pressure. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Brompheniramine/Carbetapentane/Phenylephrine Suspension if:

you are allergic to any ingredient in Brompheniramine/Carbetapentane/Phenylephrine Suspension
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brompheniramine/Carbetapentane/Phenylephrine Suspension:

Some medical conditions may interact with Brompheniramine/Carbetapentane/Phenylephrine Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat
if you have a history of asthma; lung problems (eg, emphysema); adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; phenylketonuria; or an overactive thyroid
if you are very drowsy, sedated, or are confined to a bed or chair

Some MEDICINES MAY INTERACT with Brompheniramine/Carbetapentane/Phenylephrine Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Brompheniramine/Carbetapentane/Phenylephrine Suspension’s side effects
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Brompheniramine/Carbetapentane/Phenylephrine Suspension
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Brompheniramine/Carbetapentane/Phenylephrine Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brompheniramine/Carbetapentane/Phenylephrine Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brompheniramine/Carbetapentane/Phenylephrine Suspension:

Use Brompheniramine/Carbetapentane/Phenylephrine Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Brompheniramine/Carbetapentane/Phenylephrine Suspension by mouth with or without food.
Shake well before each use.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Brompheniramine/Carbetapentane/Phenylephrine Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Brompheniramine/Carbetapentane/Phenylephrine Suspension.

Important safety information:

Brompheniramine/Carbetapentane/Phenylephrine Suspension may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Brompheniramine/Carbetapentane/Phenylephrine Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol while you are using Brompheniramine/Carbetapentane/Phenylephrine Suspension.
Do not take diet or appetite control medicines while you use Brompheniramine/Carbetapentane/Phenylephrine Suspension unless your doctor tells you to.
Brompheniramine/Carbetapentane/Phenylephrine Suspension has brompheniramine and phenylephrine in it. Before you start any new medicine, check the label to see if it has brompheniramine and phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or take Brompheniramine/Carbetapentane/Phenylephrine Suspension for longer than prescribed without checking with your doctor.
If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
Brompheniramine/Carbetapentane/Phenylephrine Suspension may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Brompheniramine/Carbetapentane/Phenylephrine Suspension. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
Brompheniramine/Carbetapentane/Phenylephrine Suspension may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Brompheniramine/Carbetapentane/Phenylephrine Suspension for a few days before the tests.
Tell your doctor or dentist that you take Brompheniramine/Carbetapentane/Phenylephrine Suspension before you receive any medical or dental care, emergency care, or surgery.
Use Brompheniramine/Carbetapentane/Phenylephrine Suspension with caution in the ELDERLY; they may be more sensitive to its effects.
Caution is advised when using Brompheniramine/Carbetapentane/Phenylephrine Suspension in CHILDREN; they may be more sensitive to its effects.
Brompheniramine/Carbetapentane/Phenylephrine Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brompheniramine/Carbetapentane/Phenylephrine Suspension while you are pregnant. It is not known if Brompheniramine/Carbetapentane/Phenylephrine Suspension is found in breast milk. Do not breast-feed while taking Brompheniramine/Carbetapentane/Phenylephrine Suspension.

Possible side effects of Brompheniramine/Carbetapentane/Phenylephrine Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Brompheniramine/Carbetapentane/Phenylephrine Suspension:

Store Brompheniramine/Carbetapentane/Phenylephrine Suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brompheniramine/Carbetapentane/Phenylephrine Suspension out of the reach of children and away from pets.

General information:

If you have any questions about Brompheniramine/Carbetapentane/Phenylephrine Suspension, please talk with your doctor, pharmacist, or other health care provider.
Brompheniramine/Carbetapentane/Phenylephrine Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brompheniramine/Carbetapentane/Phenylephrine Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

B,Med-facts

Comments (0)

30/06/10

Brompheniramine/

Carbetapentane/

Phenylephrine Liquid

Generic Name: Brompheniramine/Carbetapentane/Phenylephrine (BROME-fen-IR-a-meen/KAR-bay-ta-PEN-tane/FEN-il-EF-rin)
Brand Name: Seradex

Brompheniramine/Carbetapentane/Phenylephrine Liquid is used for:

Brompheniramine/Carbetapentane/Phenylephrine Liquid is an antihistamine, decongestant, and cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, which relieves congestion and pressure. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Brompheniramine/Carbetapentane/Phenylephrine Liquid if:

you are allergic to any ingredient in Brompheniramine/Carbetapentane/Phenylephrine Liquid
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brompheniramine/Carbetapentane/Phenylephrine Liquid:

Some medical conditions may interact with Brompheniramine/Carbetapentane/Phenylephrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat
if you have a history of asthma; lung problems (eg, emphysema); adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; phenylketonuria; or an overactive thyroid
if you are very drowsy, sedated, or are confined to a bed or chair

Some MEDICINES MAY INTERACT with Brompheniramine/Carbetapentane/Phenylephrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Brompheniramine/Carbetapentane/Phenylephrine Liquid’s side effects
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Brompheniramine/Carbetapentane/Phenylephrine Liquid
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Brompheniramine/Carbetapentane/Phenylephrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brompheniramine/Carbetapentane/Phenylephrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brompheniramine/Carbetapentane/Phenylephrine Liquid:

Use Brompheniramine/Carbetapentane/Phenylephrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Brompheniramine/Carbetapentane/Phenylephrine Liquid by mouth with or without food.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Brompheniramine/Carbetapentane/Phenylephrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Brompheniramine/Carbetapentane/Phenylephrine Liquid.

Important safety information:

Brompheniramine/Carbetapentane/Phenylephrine Liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Brompheniramine/Carbetapentane/Phenylephrine Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol while you are using Brompheniramine/Carbetapentane/Phenylephrine Liquid.
Do not take diet or appetite control medicines while you use Brompheniramine/Carbetapentane/Phenylephrine Liquid unless your doctor tells you to.
Brompheniramine/Carbetapentane/Phenylephrine Liquid has brompheniramine and phenylephrine in it. Before you start any new medicine, check the label to see if it has brompheniramine and phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or take Brompheniramine/Carbetapentane/Phenylephrine Liquid for longer than prescribed without checking with your doctor.
If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
Brompheniramine/Carbetapentane/Phenylephrine Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Brompheniramine/Carbetapentane/Phenylephrine Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Brompheniramine/Carbetapentane/Phenylephrine Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Brompheniramine/Carbetapentane/Phenylephrine Liquid for a few days before the tests.
Tell your doctor or dentist that you take Brompheniramine/Carbetapentane/Phenylephrine Liquid before you receive any medical or dental care, emergency care, or surgery.
Use Brompheniramine/Carbetapentane/Phenylephrine Liquid with caution in the ELDERLY; they may be more sensitive to its effects.
Caution is advised when using Brompheniramine/Carbetapentane/Phenylephrine Liquid in CHILDREN; they may be more sensitive to its effects.
Brompheniramine/Carbetapentane/Phenylephrine Liquid should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brompheniramine/Carbetapentane/Phenylephrine Liquid while you are pregnant. It is not known if Brompheniramine/Carbetapentane/Phenylephrine Liquid is found in breast milk. Do not breast-feed while taking Brompheniramine/Carbetapentane/Phenylephrine Liquid.

Possible side effects of Brompheniramine/Carbetapentane/Phenylephrine Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe or persistent nervousness, restlessness, or trouble sleeping; tremor; vision changes.

If OVERDOSE is suspected:

Proper storage of Brompheniramine/Carbetapentane/Phenylephrine Liquid:

Store Brompheniramine/Carbetapentane/Phenylephrine Liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brompheniramine/Carbetapentane/Phenylephrine Liquid out of the reach of children and away from pets.

General information:

If you have any questions about Brompheniramine/Carbetapentane/Phenylephrine Liquid, please talk with your doctor, pharmacist, or other health care provider.
Brompheniramine/Carbetapentane/Phenylephrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brompheniramine/Carbetapentane/Phenylephrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

B,Med-facts

Comments (0)

30/06/10

Brompheniramine/

Codeine Syrup

Generic Name: Brompheniramine/Codeine (BROME-fen-IR-a-meen/KOE-deen)
Brand Name: Nalex AC

Brompheniramine/Codeine Syrup is used for:

Relieving runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Brompheniramine/Codeine Syrup is an antihistamine and narcotic cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Brompheniramine/Codeine Syrup if:

you are allergic to any ingredient in Brompheniramine/Codeine Syrup or any other codeine- or morphine-related medicine
you have severe high blood pressure, severe heart blood vessel disease, angle-closure glaucoma, or peptic ulcers
you are unable to urinate or are having an asthma attack
you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brompheniramine/Codeine Syrup:

Some medical conditions may interact with Brompheniramine/Codeine Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have heart blood vessel problems, irregular heartbeat, or any other heart problems (eg, cor pulmonale)
if you have a history of high blood pressure; diabetes; liver or kidney problems; stroke; glaucoma or increased pressure in the eye; a blockage of your bladder, stomach, or bowels; ulcers; trouble urinating; an enlarged prostate or other prostate problems; or thyroid problems
if you have a history of asthma, chronic cough, lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea, slow or irregular breathing), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
if you have severe drowsiness, recent head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, or a seizure disorder (eg, epilepsy)
if you have very poor health or a history of constipation, stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent stomach, bowel, or urinary surgery
if you have a history of alcohol or substance abuse or suicidal thoughts or behavior
if you are taking medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with Brompheniramine/Codeine Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergics (eg, scopolamine) because serious bowel motility problem (paralytic ileus) may occur
Cimetidine, furazolidone, HIV protease inhibitors (eg, ritonavir), MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Brompheniramine/Codeine Syrup’s side effects
Narcotic pain medicines (eg, hydrocodone) because the risk of their side effects may be increased by Brompheniramine/Codeine Syrup
Naltrexone, quinidine, or rifamycins (eg, rifampin) because they may decrease Brompheniramine/Codeine Syrup’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brompheniramine/Codeine Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brompheniramine/Codeine Syrup:

Use Brompheniramine/Codeine Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Brompheniramine/Codeine Syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Brompheniramine/Codeine Syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Brompheniramine/Codeine Syrup.

Important safety information:

Brompheniramine/Codeine Syrup may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Brompheniramine/Codeine Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Brompheniramine/Codeine Syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Brompheniramine/Codeine Syrup may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Brompheniramine/Codeine Syrup has brompheniramine in it. Before you start any new medicine, check the label to see if it has brompheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If your cough or other symptoms persist for more than 1 week, come back, or if you also have fever, rash, or persistent headache, check with your doctor.
Brompheniramine/Codeine Syrup may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Brompheniramine/Codeine Syrup for a few days before the tests.
Brompheniramine/Codeine Syrup may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Brompheniramine/Codeine Syrup. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Tell your doctor or dentist that you take Brompheniramine/Codeine Syrup before you receive any medical or dental care, emergency care, or surgery.
Use Brompheniramine/Codeine Syrup with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.
Caution is advised when using Brompheniramine/Codeine Syrup in CHILDREN; they may be more sensitive to its effects, especially excitability.
Brompheniramine/Codeine Syrup should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brompheniramine/Codeine Syrup while you are pregnant. Do not take Brompheniramine/Codeine Syrup if you are in the third trimester of pregnancy. It is not known if Brompheniramine/Codeine Syrup is found in breast milk. Do not breast-feed while taking Brompheniramine/Codeine Syrup.

When used for long periods of time or at high doses, Brompheniramine/Codeine Syrup may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Brompheniramine/Codeine Syrup stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Brompheniramine/Codeine Syrup. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Brompheniramine/Codeine Syrup, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Brompheniramine/Codeine Syrup:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; thickening of mucus secretions; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, double vision, or other vision changes; confusion; difficulty urinating or inability to urinate; fast, slow, or irregular heartbeat; loss of coordination; mood or mental changes; nervousness; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; tremor; trouble sleeping; uncontrolled muscle movements; unusual bruising or bleeding; unusual weakness or tiredness.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Brompheniramine/Codeine Syrup:

Store Brompheniramine/Codeine Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brompheniramine/Codeine Syrup out of the reach of children and away from pets.

General information:

If you have any questions about Brompheniramine/Codeine Syrup, please talk with your doctor, pharmacist, or other health care provider.
Brompheniramine/Codeine Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brompheniramine/Codeine Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

B,Med-facts

Comments (0)

30/06/10

Brompheniramine/

Codeine

Generic Name: Brompheniramine/Codeine (BROME-fen-IR-a-meen/KOE-deen)
Brand Name: Examples include BroveX CB and BroveX CBX

Brompheniramine/Codeine is used for:

Relieving runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Brompheniramine/Codeine is an antihistamine and narcotic cough suppressant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Brompheniramine/Codeine if:

you are allergic to any ingredient in Brompheniramine/Codeine or any other codeine- or morphine-related medicine
you have severe high blood pressure, severe heart blood vessel disease, angle-closure glaucoma, or peptic ulcers
you are unable to urinate or are having an asthma attack
you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brompheniramine/Codeine:

Some medical conditions may interact with Brompheniramine/Codeine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have heart blood vessel problems, irregular heartbeat, or any other heart problems (eg, cor pulmonale)
if you have a history of high blood pressure; diabetes; liver or kidney problems; stroke; glaucoma or increased pressure in the eye; a blockage of your bladder, stomach, or bowels; ulcers; trouble urinating; an enlarged prostate or other prostate problems; or thyroid problems
if you have a history of asthma, chronic cough, lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea, slow or irregular breathing), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
if you have severe drowsiness, recent head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, or a seizure disorder (eg, epilepsy)
if you have very poor health or a history of constipation, stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent stomach, bowel, or urinary surgery
if you have a history of alcohol or substance abuse or suicidal thoughts or behavior
if you are taking medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with Brompheniramine/Codeine. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticholinergics (eg, scopolamine) because serious bowel motility problem (paralytic ileus) may occur
Cimetidine, furazolidone, HIV protease inhibitors (eg, ritonavir), MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Brompheniramine/Codeine’s side effects
Narcotic pain medicines (eg, hydrocodone) because the risk of their side effects may be increased by Brompheniramine/Codeine
Naltrexone, quinidine, or rifamycins (eg, rifampin) because they may decrease Brompheniramine/Codeine’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brompheniramine/Codeine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brompheniramine/Codeine:

Use Brompheniramine/Codeine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Brompheniramine/Codeine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
If you miss a dose of Brompheniramine/Codeine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Brompheniramine/Codeine.

Important safety information:

Brompheniramine/Codeine may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Brompheniramine/Codeine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Brompheniramine/Codeine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Brompheniramine/Codeine may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Brompheniramine/Codeine has brompheniramine in it. Before you start any new medicine, check the label to see if it has brompheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Do not use Brompheniramine/Codeine for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
If your cough or other symptoms persist for more than 5 days, come back, or if you also have fever, rash, or persistent headache, check with your doctor.
Brompheniramine/Codeine may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Brompheniramine/Codeine for a few days before the tests.
Brompheniramine/Codeine may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Brompheniramine/Codeine. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Tell your doctor or dentist that you take Brompheniramine/Codeine before you receive any medical or dental care, emergency care, or surgery.
Use Brompheniramine/Codeine with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.
Caution is advised when using Brompheniramine/Codeine in CHILDREN; they may be more sensitive to its effects, especially excitability.
Brompheniramine/Codeine should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brompheniramine/Codeine while you are pregnant. Do not take Brompheniramine/Codeine if you are in the third trimester of pregnancy. It is not known if Brompheniramine/Codeine is found in breast milk. Do not breast-feed while taking Brompheniramine/Codeine.

When used for long periods of time or at high doses, Brompheniramine/Codeine may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Brompheniramine/Codeine stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Brompheniramine/Codeine. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Brompheniramine/Codeine, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Brompheniramine/Codeine:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; thickening of mucus secretions; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision, double vision, or other vision changes; confusion; difficulty urinating or inability to urinate; fast, slow, or irregular heartbeat; loss of coordination; mood or mental changes; nervousness; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; tremor; trouble sleeping; uncontrolled muscle movements; unusual bruising or bleeding; unusual weakness or tiredness.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Brompheniramine/Codeine:

Store Brompheniramine/Codeine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brompheniramine/Codeine out of the reach of children and away from pets.

General information:

If you have any questions about Brompheniramine/Codeine, please talk with your doctor, pharmacist, or other health care provider.
Brompheniramine/Codeine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brompheniramine/Codeine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

B,Med-facts

Comments (0)

30/06/10

Brompheniramine/

Codeine/

Phenylephrine Liquid

Generic Name: Brompheniramine/Codeine/Phenylephrine (BROME-fen-IR-a-meen/KOE-deen/FEN-il-EF-rin)
Brand Name: M-End PE

Brompheniramine/Codeine/Phenylephrine Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Brompheniramine/Codeine/Phenylephrine Liquid is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Brompheniramine/Codeine/Phenylephrine Liquid if:

you are allergic to any ingredient in Brompheniramine/Codeine/Phenylephrine Liquid or any other codeine- or morphine-related medicine (eg, oxycodone)
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, severe heart problems, peptic ulcer, or narrow-angle glaucoma
you are unable to urinate or are having an asthma attack
you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Brompheniramine/Codeine/Phenylephrine Liquid:

Some medical conditions may interact with Brompheniramine/Codeine/Phenylephrine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat
if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems (eg, heart disease); high or low blood pressure; low blood volume; diabetes; blood vessel problems; stroke; glaucoma; liver problems; a blockage of your stomach, bladder, or intestines; trouble urinating; an enlarged prostate or other prostate problems; pancreas problems (eg, pancreatitis); or thyroid problems
if you have a history of asthma or other breathing problems (eg, sleep apnea), chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
if you have severe drowsiness, trouble sleeping, recent head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, or a seizure disorder (eg, epilepsy)
if you have a history of constipation, stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent stomach, bowel, or urinary surgery
if you have a history of mental or mood problems (eg, depression), suicidal thoughts or actions, or alcohol or other substance abuse
if you are in poor health or are very overweight
if you take medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with Brompheniramine/Codeine/Phenylephrine Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), cimetidine, furazolidone, HIV protease inhibitors (eg, ritonavir), MAOIs (eg, phenelzine), muscle relaxants (eg, cyclobenzaprine), opioid analgesics (eg, hydrocodone), phenothiazines (eg, chlorpromazine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Brompheniramine/Codeine/Phenylephrine Liquid’s side effects
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Naltrexone, quinidine, or rifamycins (eg, rifampin) because they may decrease Brompheniramine/Codeine/Phenylephrine Liquid’s effectiveness
Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Brompheniramine/Codeine/Phenylephrine Liquid
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Brompheniramine/Codeine/Phenylephrine Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Brompheniramine/Codeine/Phenylephrine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Brompheniramine/Codeine/Phenylephrine Liquid:

Use Brompheniramine/Codeine/Phenylephrine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Brompheniramine/Codeine/Phenylephrine Liquid by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
Take Brompheniramine/Codeine/Phenylephrine Liquid with a full glass of water (8 oz/240 mL).
Drink plenty of water while taking Brompheniramine/Codeine/Phenylephrine Liquid.
If you miss a dose of Brompheniramine/Codeine/Phenylephrine Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Brompheniramine/Codeine/Phenylephrine Liquid.

Important safety information:

Brompheniramine/Codeine/Phenylephrine Liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Brompheniramine/Codeine/Phenylephrine Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Brompheniramine/Codeine/Phenylephrine Liquid may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Do not drink alcohol or use medicines that may cause drowsiness (eg, muscle relaxers, sleep aids) while you are using Brompheniramine/Codeine/Phenylephrine Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Do not take diet or appetite control medicines while you take Brompheniramine/Codeine/Phenylephrine Liquid without checking with your doctor.
Brompheniramine/Codeine/Phenylephrine Liquid has phenylephrine and brompheniramine in it. Before you start any new medicine, check the label to see if it has phenylephrine or brompheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do not use Brompheniramine/Codeine/Phenylephrine Liquid for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If your symptoms do not get better within 7 days, if they get worse, or if they occur along with a fever or persistent headache, check with your doctor.
Brompheniramine/Codeine/Phenylephrine Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Brompheniramine/Codeine/Phenylephrine Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Brompheniramine/Codeine/Phenylephrine Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Brompheniramine/Codeine/Phenylephrine Liquid for a few days before the tests.
Tell your doctor or dentist that you take Brompheniramine/Codeine/Phenylephrine Liquid before you receive any medical or dental care, emergency care, or surgery.
Use Brompheniramine/Codeine/Phenylephrine Liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, low blood pressure, excitability, dry mouth, and trouble urinating.
Caution is advised when using Brompheniramine/Codeine/Phenylephrine Liquid in CHILDREN; they may be more sensitive to its effects, especially excitability.
Brompheniramine/Codeine/Phenylephrine Liquid should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Brompheniramine/Codeine/Phenylephrine Liquid while you are pregnant. Do not take Brompheniramine/Codeine/Phenylephrine Liquid in the third trimester of pregnancy. It is not known if Brompheniramine/Codeine/Phenylephrine Liquid is found in breast milk. Do not breast-feed while taking Brompheniramine/Codeine/Phenylephrine Liquid.

Some people who use Brompheniramine/Codeine/Phenylephrine Liquid for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.

If you stop taking Brompheniramine/Codeine/Phenylephrine Liquid suddenly, you may have WITHDRAWAL symptoms. These may include anxiety, irregular heartbeat, irritability, restlessness, trouble sleeping, and unusual sweating.

Possible side effects of Brompheniramine/Codeine/Phenylephrine Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficulty urinating or inability to urinate; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; mental or mood changes (eg, irritability); ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; severe or persistent trouble sleeping; shallow breathing; tremor; uncontrolled muscle movements; unusual bruising or bleeding; unusual weakness or tiredness; vision changes or blurred vision.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; cold and clammy skin; coma; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Brompheniramine/Codeine/Phenylephrine Liquid:

Store Brompheniramine/Codeine/Phenylephrine Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Brompheniramine/Codeine/Phenylephrine Liquid out of the reach of children and away from pets.

General information:

If you have any questions about Brompheniramine/Codeine/Phenylephrine Liquid, please talk with your doctor, pharmacist, or other health care provider.
Brompheniramine/Codeine/Phenylephrine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Brompheniramine/Codeine/Phenylephrine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

B,Med-facts

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