zinc gluconate
30/06/10
Generic Name: zinc gluconate (ZINK GLUE koe nate)
Brand names: Orazinc, Orazinc 110, Orazinc 110(obsolete)
What is zinc gluconate?
Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues.
Zinc gluconate is used to treat and to prevent zinc deficiency.
Zinc gluconate may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about zinc gluconate?
Before using zinc gluconate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc gluconate if you have certain medical conditions.
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc gluconate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc gluconate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc gluconate.
What should I discuss with my healthcare provider before taking zinc gluconate?
Before using zinc gluconate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc gluconate if you have certain medical conditions.
It is not known whether zinc gluconate will harm an unborn baby. Do not take zinc gluconate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc gluconate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take zinc gluconate?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Take zinc gluconate with a full glass of water. Take zinc gluconate with food if it upsets your stomach.
Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc gluconate. The recommended dietary allowance of zinc gluconate increases with age. Follow your healthcare provider’s instructions. You may also consult the National Academy of Sciences “Dietary Reference Intake” or the U.S. Department of Agriculture’s “Dietary Reference Intake” (formerly “Recommended Daily Allowances” or RDA) listings for more information.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, severe vomiting, dehydration, and restlessness.
What should I avoid while taking zinc gluconate?
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc gluconate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc gluconate side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
-
nausea; or
-
upset stomach.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Zinc gluconate Dosing Information
Usual Adult Dose for Dietary Supplement:
Dosage: 105 mg to 350 mg daily.
What other drugs will affect zinc gluconate?
The following drugs can interact with or be made less effective by zinc gluconate. Tell your doctor if you are using any of these:
-
a blood thinner such as warfarin (Coumadin);
-
methyltestosterone (Android, Methitest, Oreton);
-
penicillamine (Cuprimine, Depen);
-
risedronate (Actonel);
-
a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or
-
an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), and others.
This list is not complete and other drugs may interact with zinc gluconate. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zinc gluconate.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 4.01. Revision Date: 03/01/2010 2:05:25 PM.
zinc oxide
30/06/10
Generic Name: zinc oxide (topical) (ZINK OX ide)
Brand names: ARC, Balmex, Boudreaux Butt Paste, Caldesene, Calmol-4 Suppository, Critic Aid, Delazinc, Desitin, Desitin Creamy, Desitin Creamy Diaper Rash Ointment, Diaper Rash Ointment, Diaper Relief, Flanders Buttocks Ointment, Medi-Paste, PeriGuard, Pinxav, RVPaque, Seniortopix Healix, Sportz Block Dark, Sportz Block Light, Sportz Block Medium, Triple Paste, Tronolane Suppositories, Znlin, …show all 43 brand names.
What is zinc oxide topical?
Zinc oxide is a mineral.
Zinc oxide topical (applied to the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.
Zinc oxide topical may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about zinc oxide topical?
Do not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment.
Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.
Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.
What should I discuss with my health care provider before using zinc oxide topical?
Do not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.
Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while you are using this medication. It is not known whether zinc oxide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use zinc oxide topical?
Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.
Apply enough of this medication to cover the entire area to be treated. Zinc oxide often leaves a thin white residue that may not be entirely rubbed in.
To treat chapped skin, minor burn wounds, or other skin irritations, use the medication as often as needed. Apply a thin layer to the affected area and rub in gently.
To treat diaper rash, use this medication each time the diaper is changed. It is especially important to apply the medication at bedtime or whenever there will be a long period of time between diaper changes.
Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.
When using the powder form of this medicine, pour the powder slowly to avoid a large puff into the air. Do not allow a baby to handle a powder bottle during use. Always close the lid after using the powder.
Zinc oxide rectal suppositories come with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Wash your hands before and after inserting a rectal suppository.
Try to empty your bowel and bladder just before using the suppository. Cleanse and dry your rectal area thoroughly.
Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.
For best results from the suppository, lie down after inserting it and hold in the suppository. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in.
Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment.
Store this medication at room temperature away from moisture and heat. Keep the lid or cap tightly closed. You may store zinc oxide rectal suppositories in a refrigerator to prevent melting.
What happens if I miss a dose?
Since zinc oxide topical is used as needed, it is not likely that you will be on a dosing schedule. Using extra zinc oxide to make up a missed dose will not make the medication more effective.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine, or if anyone has accidentally swallowed it.
An overdose of zinc oxide applied to the skin is unlikely to occur.
What should I avoid while using zinc oxide topical?
Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.
Zinc oxide topical side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Zinc oxide Dosing Information
Usual Adult Dose for Dermatologic Lesion:
Zinc oxide topical 30% ointment:
Apply topically to affected area as needed.
Usual Pediatric Dose for Dermatologic Lesion:
Zinc oxide topical 30% ointment:
Apply topically to affected area as needed.
Usual Pediatric Dose for Diaper Rash:
Zinc oxide topical 10% ointment:
Zinc oxide topical 11.3% stick:
Zinc oxide topical 30% ointment:
Clean the diaper area and allow to dry. Apply liberal amount topically with each diaper change.
What other drugs will affect zinc oxide topical?
Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.
It is not likely that other drugs you take orally or inject will have any effect on topically applied zinc oxide. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zinc oxide topical.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.05. Revision Date: 4/12/2009 4:40:16 PM.
Zinc 50 mg Pink
30/06/10
Generic Name: zinc sulfate (ZINK SUL fate)
Brand Names: Orazinc 110, Orazinc 220, Verazinc, Zinc-220, Zincate
What is Zinc 50 mg Pink (zinc sulfate)?
Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues.
Zinc sulfate is used to treat and to prevent zinc deficiency.
Zinc sulfate may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Zinc 50 mg Pink (zinc sulfate)?
Before using zinc sulfate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc sulfate if you have certain medical conditions.
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc sulfate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc sulfate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc sulfate.
What should I discuss with my healthcare provider before taking Zinc 50 mg Pink (zinc sulfate)?
Before using zinc sulfate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc sulfate if you have certain medical conditions.
It is not known whether zinc sulfate will harm an unborn baby. Do not take zinc sulfate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc sulfate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Zinc 50 mg Pink (zinc sulfate)?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Take zinc sulfate with a full glass of water. Take zinc sulfate with food if it upsets your stomach.
Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc sulfate. The recommended dietary allowance of zinc sulfate increases with age. Follow your healthcare provider’s instructions. You may also consult the National Academy of Sciences “Dietary Reference Intake” or the U.S. Department of Agriculture’s “Dietary Reference Intake” (formerly “Recommended Daily Allowances” or RDA) listings for more information.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, severe vomiting, dehydration, and restlessness.
What should I avoid while taking Zinc 50 mg Pink (zinc sulfate)?
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc sulfate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc 50 mg Pink (zinc sulfate) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
-
nausea; or
-
upset stomach.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Zinc 50 mg Pink (zinc sulfate)?
The following drugs can interact with or be made less effective by zinc sulfate. Tell your doctor if you are using any of these:
-
a blood thinner such as warfarin (Coumadin);
-
methyltestosterone (Android, Methitest, Oreton);
-
penicillamine (Cuprimine, Depen);
-
risedronate (Actonel);
-
a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or
-
an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), and others.
This list is not complete and other drugs may interact with zinc sulfate. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zinc sulfate.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.01. Revision Date: 03/01/2010 11:52:50 AM.
zinc acetate
30/06/10
Generic Name: zinc acetate (ZINK AS e tate)
Brand Names: Galzin
What is zinc acetate?
Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues.
Zinc acetate is used to treat and to prevent zinc deficiency.
Zinc acetate may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about zinc acetate?
Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions.
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc acetate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc acetate.
What should I discuss with my healthcare provider before taking zinc acetate?
Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions.
It is not known whether zinc acetate will harm an unborn baby. Do not take zinc acetate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc acetate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take zinc acetate?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Take zinc acetate with a full glass of water. Take zinc acetate with food if it upsets your stomach.
Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc acetate. The recommended dietary allowance of zinc acetate increases with age. Follow your healthcare provider’s instructions. You may also consult the National Academy of Sciences “Dietary Reference Intake” or the U.S. Department of Agriculture’s “Dietary Reference Intake” (formerly “Recommended Daily Allowances” or RDA) listings for more information.
Store at room temperature away from moisture and heat.
See also: Zinc acetate dosage in more detail
What happens if I miss a dose?
Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, severe vomiting, dehydration, and restlessness.
What should I avoid while taking zinc acetate?
Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa.
Zinc acetate side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
-
nausea; or
-
upset stomach.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Zinc acetate Dosing Information
Usual Adult Dose for Wilson’s Disease:
Maintenance (following initial chelation therapy):
50 mg orally 3 times a day on an empty stomach. All doses should be administered at least one hour before or two to three hours after consumption of any food and beverage other than water.,
What other drugs will affect zinc acetate?
The following drugs can interact with or be made less effective by zinc acetate. Tell your doctor if you are using any of these:
-
a blood thinner such as warfarin (Coumadin);
-
methyltestosterone (Android, Methitest, Oreton);
-
penicillamine (Cuprimine, Depen);
-
risedronate (Actonel);
-
a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap); or
-
an antibiotic such as ciprofloxacin (Cipro), ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), and others.
This list is not complete and other drugs may interact with zinc acetate. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zinc acetate.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 4.01. Revision Date: 03/01/2010 2:00:27 PM.
zileuton
30/06/10
Generic Name: zileuton (zye LOO ton)
Brand names: Zyflo CR, Zyflo
What is zileuton?
Zileuton is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.
Zileuton is used to prevent asthma attacks in adults and children as young as 12 years old.
Zileuton may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about zileuton?
Call your doctor at once if you have nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). These may be early signs of liver problems. Do not use zileuton to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. It may take up to a few weeks of using this medicine before your symptoms improve. For best results, keep using zileuton as directed, even if you feel fine. Having no asthma symptoms is a sign that the medication is working.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
Avoid drinking alcohol while you are taking zileuton. Alcohol can increase your risk of liver damage. Call your doctor at once if you have any mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself.
What should I discuss with my healthcare provider before taking zileuton?
Do not use this medication if you are allergic to zileuton, or if you have liver disease.
If you drink large amounts of alcohol or have a history of liver disease, you may need a dose adjustment or special tests to safely take zileuton
FDA pregnancy category C. It is not known whether zileuton is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether zileuton passes into breast milk or if it could harm a nursing baby. . Do not take zileuton without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child without a doctor’s advice.
How should I take zileuton?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Take zileuton with a full glass of water. Zileuton tablets and extended-release tablets contain the same amount of the drug, but they are not taken in the same way. Follow your doctor’s instructions.
Zileuton tablets are usually taken 4 times daily, with meals and at bedtime. Zileuton tablets may be swallowed whole or split in half to make swallowing easier.
Zileuton extended-release tablets are usually taken twice daily, within 1 hour after your morning and evening meals.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. Do not use zileuton to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. It may take up to a few weeks of using this medicine before your symptoms improve. For best results, keep using zileuton as directed, even if you feel fine. Having no asthma symptoms is a sign that the medication is working.
Asthma is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor, even if you have no asthma symptoms.
Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.
To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
Store zileuton at room temperature away from moisture and heat.
See also: Zileuton dosage in more detail
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a zileuton overdose are not known.
What should I avoid while taking zileuton?
Avoid situations or activities that may trigger an asthma attack.
Avoid drinking alcohol while taking zileuton. Alcohol may increase your risk of liver damage.
Zileuton side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
-
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
-
skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
-
mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself; or
-
worsening asthma symptoms.
Less serious side effects may include:
-
cold symptoms such as stuffy nose, sinus pain, sneezing, sore throat;
-
headache;
-
diarrhea, upset stomach;
-
weakness; or
-
muscle pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Zileuton Dosing Information
Usual Adult Dose for Asthma — Maintenance:
600 mg tablets:
600 mg orally four times a day, with meals and at bedtime.
600 mg extended release tablets
2 tablets (1200 mg) orally twice daily, within 1 hour after morning or evening meals, for a total daily dose of 2400 mg.
Usual Pediatric Dose for Asthma — Maintenance:
> 12 years:
600 mg tablets:
600 mg orally four times a day, with meals and at bedtime.
600 mg extended release tablets
2 tablets (1200 mg) orally twice daily, within 1 hour after morning or evening meals, for a total daily dose of 2400 mg.
What other drugs will affect zileuton?
Before taking zileuton, tell your doctor if you are taking any of the following drugs:
-
a blood thinner such as warfarin (Coumadin);
-
theophylline (Theo-Dur, Theolair, Elixophyllin, Slo-Phyllin, others); or
-
propranolol (Inderal).
This list is not complete and there may be other drugs that can interact with zileuton. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zileuton.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 3.09. Revision Date: 06/25/2009 11:04:33 AM.
zilactin-B
30/06/10
Generic Name: benzocaine topical (BENZ oh kane TOP ik al)
Brand Names: Americaine, Americaine Anesthetic Lubricant, Americaine Hemorrhoidal, Anacaine, Anbesol Baby, Anbesol Cold Sore, Anbesol Gel, Anbesol Liquid, Anbesol Liquid Cool Mint, Anbesol Maximum Strength, Babee Teething Lotion, Benz-O-Sthetic, Benzo-O-Stetic, Boil Ease Pain Relieving, Cepacol Dual Relief Sore Throat Cherry, Cepacol Dual Relief Sore Throat Mint, Cepacol Extra Strength, Cepacol Extra Strength Cherry, Cepacol Extra Strength Cherry Sugar Free, Cepacol Extra Strength Citrus, Cepacol Extra Strength Honey Lemon, Cepacol Extra Strength Menthol, Cepacol Extra Strength Menthol Sugar Free, Cepacol Fizzlers, Dent-O-Kain, Dermoplast, Dermoplast Antibacterial, Detane, Foille Plus, Hurricaine, Hurricaine Kit, Hurricaine Snap-n-Go, Lanacane, Lanacane Maximum Strength, Lanacane with Aloe, Maintain, Medicone Maximum Strength, Num-Zit, Numzident, Orabase Baby Teething Gel, Orabase Gel-B, Orabase Lip Healer, Orabase with Benzocaine, Orajel, Orajel Baby, Orajel Baby Nighttime, Orajel D, Orajel Denture, Orajel Denture Plus, Orajel Maximum Strength, Orajel Maximum Strength PM, Orajel Mouth Sore Medicine, Orajel Mouth-Aid, Orajel Severe Pain Formula, Oral Pain Relief, OraMagic Plus, Outgro Pain Relief, Retre-Gel, Rid-A-Pain, Skeeter Stik, Solarcaine Aerosol, Sting-Kill, Topex, Trocaine, Vagisil Feminine Cream, zilactin-B
What is zilactin-B (benzocaine topical)?
Benzocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Benzocaine is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.
Benzocaine topical may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about zilactin-B (benzocaine topical)?
There are many brands and forms of benzocaine topical available and not all brands are listed on this leaflet.
An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops). Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.
Use the smallest amount of this medication needed to numb the skin or relieve pain. Do not use large amounts of benzocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.
Do not use benzocaine topical if you have a blood cell disorder called methemoglobinemia.
Before using benzocaine topical, tell your doctor if you have any type of inherited enzyme deficiency, a breathing disorder such as asthma or emphysema, or if you smoke.
Call your doctor if your symptoms do not improve or if they get worse within the first 7 days of using benzocaine topical. Also call your doctor if your symptoms had cleared up but then came back.
If you are treating a sore throat, call your doctor if the pain is severe or lasts longer than 2 days, especially if you also develop a fever, headache, skin rash, swelling, nausea, vomiting, cough, or breathing problems.
What should I discuss with my health care provider before using zilactin-B (benzocaine topical)?
An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops). Do not use benzocaine topical if you have a blood cell disorder called methemoglobinemia.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use benzocaine topical:
-
asthma, bronchitis, emphysema, or other breathing disorder;
-
heart disease;
-
a personal or family history of methemoglobinemia, or any genetic enzyme deficiency; or
-
if you smoke.
FDA pregnancy category C. It is not known whether benzocaine topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.. It is not known whether benzocaine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medicine on a child younger than 1 year old.
How should I use zilactin-B (benzocaine topical)?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.
Use the smallest amount of medicine needed to numb the skin or relieve pain. Do not use large amounts of benzocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.
This medication comes with instructions for safe and effective application. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
To treat minor skin conditions, apply a thin layer of benzocaine topical to the affected area up to 4 times per day. If using the spray, hold the container 6 to 12 inches away from the skin. Do not spray this medication onto your face. Spray it instead on your hands and then rub it onto the face, avoiding contact with your eyes.
To treat hemorrhoids, clean the area with soap and water before applying benzocaine topical. Apply the medication up to 6 times per day. If you are using the rectal suppository, try to empty your bowel and bladder before inserting the suppository. Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.
Do not use benzocaine topical to treat large skin areas or deep puncture wounds. Avoid using the medicine on skin that is raw or blistered, such as a severe burn or abrasion.
Call your doctor if your symptoms do not improve or if they get worse within the first 7 days of using benzocaine topical. Also call your doctor if your symptoms had cleared up but then came back.
If you are treating a sore throat, call your doctor if the pain is severe or lasts longer than 2 days, especially if you also develop a fever, headache, skin rash, swelling, nausea, vomiting, cough, or breathing problems.
Store at room temperature away from moisture and heat. Do not allow the liquid form of this medicine to freeze.
What happens if I miss a dose?
Since benzocaine topical is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of benzocaine topical applied to the skin can cause life-threatening side effects such as uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).
What should I avoid while taking zilactin-B (benzocaine topical)?
Benzocaine topical is for use only on the surface of your body, or just inside the vagina or rectum. Avoid getting this medication in your eyes. Avoid swallowing the gel, liquid, or ointment while applying it to your gums or the inside of your mouth. The throat spray or oral lozenge may be swallowed gradually during use.
Do not apply other medications to the same affected areas you treat with benzocaine topical, unless your doctor has told you otherwise.
Avoid eating within 1 hour after using benzocaine topical on your gums or inside your mouth.
zilactin-B (benzocaine topical) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using benzocaine topical and call your doctor at once if you have any of these serious side effects:
-
severe burning, stinging, or sensitivity where the medicine is applied;
-
swelling, warmth, or redness;
-
oozing, blistering, or any signs of infection; or
-
headache, weakness, dizziness, breathing problems, fast heart rate, and gray or bluish colored skin (rare but serious side effects of benzocaine).
Less serious side effects may include:
-
mild stinging, burning, or itching where the medicine is applied;
-
skin tenderness or redness; or
-
dry white flakes where the medicine was applied.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect zilactin-B (benzocaine topical)?
It is not likely that other drugs you take orally or inject will have an effect on topically applied benzocaine topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about benzocaine topical.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.01. Revision Date: 05/17/2010 3:24:38 PM.
Zilactin-L
30/06/10
Generic Name: lidocaine topical (LYE doe kane TOP i kal)
Brand Names: AneCream, AneCream with Tegaderm, Anestacon, Bactine, LidaMantle, Lidocream, Lidoderm, Lidosense5, LMX 4, LMX 4 with Tegaderm, LMX 5, Medi-Quik Spray, Senatec, Xylocaine Jelly, Xylocaine Topical
What is Zilactin-L (lidocaine topical)?
Lidocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Lidocaine topical (for use on the skin) is used to reduce pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, hemorrhoids, and burns.
Lidocaine topical may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Zilactin-L (lidocaine topical)?
An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). However, overdose has also occurred in women treated with a numbing medicine before having a mammography. Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops). Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.
Use the smallest amount of this medication needed to numb the skin or relieve pain. Do not use large amounts of lidocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.
Keep both used and unused lidocaine topical patches out of the reach of children or pets. The amount of lidocaine in the skin patches could be harmful to a child or pet who accidentally sucks on or swallows the patch. Seek emergency medical attention if this happens.
What should I discuss with my healthcare provider before using Zilactin-L (lidocaine topical)?
An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood.
Overdose is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). However, overdose has also occurred in women treated with a numbing medicine before having a mammography. Symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).
Do not use lidocaine topical if you are allergic to any other type of numbing medicine.
Before using lidocaine topical, tell your doctor if you are allergic to any drugs, or if you have liver disease, or broken, swollen, or damaged skin. You may not be able to use lidocaine topical, or you may need dosage adjustments or special tests during treatment.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Lidocaine topical can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use Zilactin-L (lidocaine topical)?
Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended.
Lidocaine topical comes in many different forms for different uses. Lidocaine topical cream, lotion, spray, solution, film, and transdermal patch are generally for use on the skin only.
If your medication comes with patient instructions for safe and effective use, follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.
Use the smallest amount of this medication needed to numb the skin or relieve pain. Do not use large amounts of lidocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.
Do not apply this medication to swollen skin areas or deep puncture wounds. Avoid using the medicine on skin that is raw or blistered, such as a severe burn or abrasion.
Lidocaine topical may be applied with your finger tips or a cotton swab. Follow your doctor’s instructions.
Store lidocaine topical at room temperature away from moisture and heat. Keep both used and unused lidocaine topical patches out of the reach of children or pets. The amount of lidocaine in the skin patches could be harmful to a child or pet who accidentally sucks on or swallows the patch. Seek emergency medical attention if this happens.
What happens if I miss a dose?
Since lidocaine topical is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Lidocaine topical applied to the skin is not likely to cause an overdose unless you apply more than the recommended dose. Overdose may also occur if you apply heat, bandages, or plastic wrap to treated skin areas.
Improper use of lidocaine topical may result in death.
Overdose symptoms may include drowsiness, confusion, nervousness, ringing in your ears, blurred vision, feeling hot or cold, numbness, muscle twitches, uneven heartbeats, seizure (convulsions), slowed breathing, or respiratory failure (breathing stops).
What should I avoid while using Zilactin-L (lidocaine topical)?
Do not allow this medication to come into contact with your eyes. If it does, rinse with water. Avoid touching the sticky side of a lidocaine skin patch while applying it.
Avoid using other topical medications on the affected area unless your doctor has told you to.
Zilactin-L (lidocaine topical) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using lidocaine topical and call your doctor at once if you have any of these serious side effects:
-
uneven heartbeats;
-
drowsiness, confusion;
-
tremors, seizure (convulsions); or
-
blurred vision.
Less serious side effects include:
-
mild irritation, redness, or swelling where the medication is applied;
-
numbness in places where the medicine is accidentally applied.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Zilactin-L (lidocaine topical)?
Before using lidocaine topical, tell your doctor if you are taking medication to treat a heart rhythm disorder, such as:
-
quinidine (Quinidex, Quinaglute);
-
disopyramide (Norpace);
-
flecainide (Tambocor);
-
mexiletine (Mexitil);
-
procainamide (Procan, Pronestyl);
-
tocainide (Tonocard); or
-
propafenone (Rythmol).
This list is not complete and there may be other drugs that can interact with lidocaine topical. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist has information about lidocaine topical.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 4.01. Revision Date: 09/14/2009 1:45:14 PM.
zidovudine
30/06/10
Generic Name: zidovudine (oral) (zye DOE vyoo deen)
Brand Names: Retrovir
What is zidovudine?
Zidovudine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Zidovudine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Zidovudine is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Zidovudine is not a cure for HIV or AIDS.
Zidovudine may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about zidovudine?
Zidovudine may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Call your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal. Zidovudine can also cause severe or life-threatening effects on your liver. Call your doctor at once if you have any of these symptoms while taking zidovudine: nausea and vomiting, diarrhea, loss of appetite, stomach pain, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Do not use zidovudine together with other combination drugs that contain zidovudine, such as Combivir or Trizivir.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
Taking zidovudine will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.
What should I discuss with my healthcare provider before taking zidovudine?
Do not use this medication if you are allergic to zidovudine, or if you are using any other drugs that contain zidovudine, such as Combivir or Trizivir.
Before taking zidovudine, tell your doctor if you are allergic to any drugs, or if you have:
- kidney disease;
- liver disease; or
-
bone marrow suppression.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Zidovudine may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Call your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal. Zidovudine can also cause severe or life-threatening effects on your liver. Call your doctor at once if you have any of these symptoms while taking zidovudine: nausea and vomiting, diarrhea, loss of appetite, stomach pain, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection while you are pregnant.
Your name may need to be listed on an antiviral pregnancy registry when you start using zidovudine. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether zidovudine had any effect on the baby.
You should not breast-feed while you are using zidovudine. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.
How should I take zidovudine?
Take zidovudine exactly as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not take zidovudine for longer than your doctor has prescribed. Follow the directions on your prescription label.
Take zidovudine with a full glass of water.
To be sure you get the correct dose of zidovudine syrup, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
It is important to use zidovudine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
Store zidovudine at room temperature away from moisture and heat.
See also: Zidovudine dosage in more detail
What happens if I miss a dose?
Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include nausea, vomiting, drowsiness, headache, or weakness.
What should I avoid while taking zidovudine?
Avoid drinking alcohol while taking zidovudine. Alcohol may increase the risk of damage to the liver.
Taking zidovudine will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.
Zidovudine side effects
Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these other serious side effects:
-
liver damage – nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
-
lactic acidosis – muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, and fast or uneven heart rate;
-
pancreatitis – severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
-
peripheral neuropathy – numbness, tingling, or pain in your hands or feet;
-
easy bruising or bleeding, unusual weakness, pale skin;
-
white patches or sores inside your mouth or on your lips;
-
fever, chills, body aches, flu symptoms; or
-
any other signs of new infection.
Less serious side effects may be more likely to occur, such as:
-
sleep problems (insomnia), strange dreams;
-
mild nausea, vomiting, stomach pain, constipation;
-
muscle or joint pain;
-
headache, tired feeling;
-
skin rash; or
-
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Zidovudine Dosing Information
Usual Adult Dose for HIV Infection:
Oral: 300 mg orally every 12 hours or 200 mg orally every 8 hours
IV: 1 mg/kg by IV infusion over 1 hour, every 4 hours around the clock, for a total daily dose of 5 to 6 mg/kg; maximum of 200 mg/dose
Duration: Therapy should be continued for as long as the patient tolerates, or until the patient is switched to another antiretroviral agent.
Usual Adult Dose for Nonoccupational Exposure:
300 mg orally every 12 hours or 200 mg orally every 8 hours, in combination with efavirenz plus (lamivudine or emtricitabine) or lopinavir-ritonavir plus (lamivudine or emtricitabine)
Prophylaxis should be initiated as soon as possible, preferably within 72 hours of exposure.
Duration: 28 days
Usual Adult Dose for Occupational Exposure:
300 mg orally every 12 hours or 200 mg orally every 8 hours
Prophylaxis should begin promptly, preferably within 1 to 2 hours postexposure.
Duration: Generally 28 days; however, the exact duration of therapy may differ based on the institution’s protocol
Usual Adult Dose for Reduction of Perinatal Transmission of HIV:
Maternal dosing: 100 mg orally 5 times a day until start of labor; however, most authorities would also consider the standard oral dosages of 300 mg every 12 hours or 200 mg every 8 hours
During labor and delivery: 2 mg/kg by IV infusion over 1 hour followed by a continuous IV infusion of 1 mg/kg/hr until clamping of the umbilical cord
Therapy should begin at 14 to 34 weeks gestation. Neonates should also be treated for 6 weeks. Despite the use of this regimen, transmission to infants may still occur in some cases.
Usual Pediatric Dose for HIV Infection:
Oral:
4 weeks to less than 18 years:
Based on body weight:
4 to less than 9 kg: 12 mg/kg orally twice a day or 8 mg/kg orally 3 times a day
9 to less than 30 kg: 9 mg/kg orally twice a day or 6 mg/kg orally 3 times a day
30 kg or more: 300 mg orally twice a day or 200 mg orally 3 times a day
Based on body surface area: 240 mg/m2 orally twice a day or 160 mg/m2 orally 3 times a day
The dosage calculated by body weight may not be the same as the dosage calculated by body surface area in some cases.
IV infusion:
6 weeks to 12 years:
Intermittent: 120 mg/m2 IV every 6 hours
Continuous: 20 mg/m2 IV per hour
13 years or older: 1 mg/kg by IV infusion over 1 hour, every 4 hours around the clock, for a total daily dose of 5 to 6 mg/kg; maximum of 200 mg/dose
Usual Pediatric Dose for Reduction of Perinatal Transmission of HIV:
Premature infants:
Oral: 2 mg/kg orally every 12 hours
IV: 1.5 mg/kg IV every 12 hours
Increase dosage frequency to every 8 hours at 4 weeks of age in neonates less than 30 weeks gestation at birth and at 2 weeks of age in neonates 30 to less than 35 weeks gestation at birth.
Full-term infants, 0 to 6 weeks:
Oral: 2 mg/kg orally every 6 hours
IV: 1.5 mg/kg IV every 6 hours
Oral treatment with zidovudine syrup should start at 8 to 12 hours after birth and should continue through 6 weeks of age. IV zidovudine may be administered to neonates unable to receive oral dosing and should be infused over 30 minutes.
What other drugs will affect zidovudine?
Before taking zidovudine, tell your doctor if you are also using:
-
atovaquone (Mepron);
-
doxorubicin (Adriamycin);
-
fluconazole (Diflucan);
-
ganciclovir (Cytovene);
-
interferon-alfa (Roferon, Intron, Rebetron);
-
methadone (Dolophine, Methadose);
-
nelfinavir (Viracept);
-
phenytoin (Dilantin);
-
probenecid (Benemid);
-
ribavirin (Rebetol, Ribasphere, Copegus Virazole);
-
ritonavir (Norvir); or
-
stavudine (Zerit).
This list is not complete and there may be other drugs that can interact with zidovudine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about zidovudine.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 8.03. Revision Date: 4/12/2009 4:22:24 PM.
ziconotide
30/06/10
Generic Name: ziconotide (zye KON oh tide)
Brand Names: Prialt
What is ziconotide?
Ziconotide is a non-narcotic pain reliever that works by blocking pain signals from the nerves to the brain.
Ziconotide is used to treat severe chronic pain in people who cannot use or do not respond to standard pain-relieving medications.
Ziconotide may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about ziconotide?
Severe psychiatric symptoms and neurological impairment may occur during treatment with ziconotide. You should not receive ziconotide if you have a history of psychiatric illness or psychotic event.
You should not use this medication if you are allergic to ziconotide, or if you have an uncontrolled bleeding or blood clotting disorder.
Ziconotide must be given only as an intrathecal injection through an infusion pump and should not be injected directly into a vein or other part of the body. Your doctor, nurse, or other healthcare provider will give you this injection.
Your doctor may occasionally change your dose or infusion pump flow rate to make sure you get the best results from this medication.
Tell your doctor if the medicine seems to stop working as well in relieving your pain. Tell your doctor if you regularly use other medicines that make you sleepy. Ziconotide can add to sleepiness caused by these other medications.
Call your doctor at once if you have a serious side effect, especially fever, neck stiffness, seizure (convulsions), extreme drowsiness or tired feeling, confusion, disorientation, hallucinations, thoughts of hurting yourself, or decreased consciousness.
What should I discuss with my healthcare provider before using ziconotide?
Severe psychiatric symptoms and neurological impairment may occur during treatment with ziconotide. You should not receive ziconotide if you have a history of psychiatric illness or psychotic event.
You should not use this medication if you are allergic to ziconotide, or if you have an uncontrolled bleeding or blood clotting disorder.
FDA pregnancy category C. It is not known whether ziconotide is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ziconotide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use ziconotide?
Ziconotide is given as an injection into the space around your spinal cord (intrathecal injection) using a computerized, portable infusion pump to control the rate of medication you receive. You may need to use this medication for a period of many years.
Ziconotide must be given only as an intrathecal injection through an infusion pump and should not be injected directly into a vein or other part of the body. Your doctor, nurse, or other healthcare provider will give you this injection.
Your doctor may occasionally change your dose or infusion pump flow rate to make sure you get the best results from this medication.
Tell your doctor if the medicine seems to stop working as well in relieving your pain.
To be sure ziconotide is helping your condition and not causing harmful effects, your doctor will need to check your progress on a regular basis. Do not miss any scheduled appointments.
If you also use a narcotic pain medication, do not stop using it suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about using less and less of the narcotic medication before stopping completely.
What happens if I miss a dose?
Since ziconotide dosing and infusion pump programming is administered by a healthcare professional, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine or if your infusion pump is not working properly.
Overdose symptoms may include extreme drowsiness, vision problems, confusion, speech problems, stiffness in your neck or back, nausea and vomiting, or loss of consciousness.
What should I avoid while using ziconotide?
Avoid drinking alcohol while you are using ziconotide. Ziconotide can cause side effects that may impair your thinking or reactions. Avoid driving or doing anything that requires you to be awake and alert.
Ziconotide side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
-
problems with memory, speech, walking, or thinking;
-
feeling like you might pass out;
-
double vision or other vision problems;
-
new or worsening muscle pain, cramps, soreness, or weakness, and/or dark urine;
-
unusual bleeding or signs of infection around the microinfusion entry or catheter exit sites;
-
fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, nausea, vomiting, and/or seizure (convulsions);
-
extreme drowsiness or tired feeling, depressed mood;
-
feeling paranoid, hostile, disoriented, or confused;
-
strange sensations in your mouth;
-
hallucinations, unusual thoughts or behavior, thoughts of hurting yourself; or
-
feeling less alert, decreased consciousness (stupor or lack of response).
Less serious side effects may include:
-
headache, joint pain;
-
mild drowsiness or weakness;
-
dizziness, spinning sensation;
-
sleep problems, unusual dreams;
-
stomach pain, diarrhea, constipation, loss of appetite;
-
urinating less than usual; or
-
loss of balance or coordination.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Ziconotide Dosing Information
Usual Adult Dose for Pain:
Initial dose: No more than 2.4 mcg per day (0.1 mcg/hour) by intrathecal (IT) administration
The dosage should be titrated to patient response. Doses may be titrated upward by up to 2.4 mcg/day (0.1 mcg/hour) at intervals of no more than 2 to 3 times per week, up to a recommended maximum of 19.2 mcg/day (0.8 mcg/hour) by day 21. Dose increases in increments of less than 2.4 mcg/day (0.1 mcg/hour) and increases in dose less frequently than 2 to 3 times per week may be used. The average dose level at the end of a 21 day clinical study was 6.9 mcg per day (0.29 mcg/hour).
Usual Geriatric Dose for Pain:
The dose selection for elderly patients should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, and cardiac function, and of concomitant diseases or other drug therapy.
Initial dose: No more than 2.4 mcg per day (0.1 mcg/hour) by intrathecal (IT) administration
The dosage should be titrated to patient response. Doses may be titrated upward by up to 2.4 mcg/day (0.1 mcg/hour) at intervals of no more than 2 to 3 times per week, up to a recommended maximum of 19.2 mcg/day (0.8 mcg/hour) by day 21. Dose increases in increments of less than 2.4 mcg/day (0.1 mcg/hour) and increases in dose less frequently than 2 to 3 times per week may be used. The average dose level at the end of a 21 day clinical study was 6.9 mcg per day (0.29 mcg/hour).
What other drugs will affect ziconotide?
Before receiving ziconotide, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). Ziconotide can add to sleepiness caused by these other medications.
Also tell your doctor if you are taking a diuretic (water pill).
This list is not complete and there may be other drugs that can interact with ziconotide. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information ziconotide.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.04. Revision Date: 4/12/2009 4:45:42 PM.
Ziana
30/06/10
Generic Name: clindamycin and tretinoin (topical) (klin da MYE sin TRET i noyn )
Brand Names: Ziana
What is clindamycin and tretinoin topical?
Clindamycin is an antibiotic. It fights bacteria in the body.
Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.
The combination of clindamycin and tretinoin is used to treat severe nodular acne in adults and children who are at least 12 years old.
Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about clindamycin and tretinoin topical?
Avoid getting this medication in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin.
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.
Although this medicine is applied to the skin, your body may absorb enough clindamycin to cause serious side effects.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Clindamycin and tretinoin topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Your skin may be more sensitive to weather extremes such as cold and wind. Protect your skin with clothing and use a moisturizing cream or lotion as needed.
What should I discuss with my health care provider before using clindamycin and tretinoin topical?
Although this medicine is applied to the skin, your body may absorb enough clindamycin to cause serious side effects.
Do not use this medication if you are allergic to clindamycin (Cleocin, Clina-Derm, Clindets), or tretinoin (Renova, Retin-A, Tretin-X), or if you have:
-
inflammation of your intestines (also called enteritis);
-
ulcerative colitis; or
-
if you have ever had severe diarrhea caused by antibiotic medicine.
Before using clindamycin and tretinoin topical, tell your doctor if you are allergic to any drugs, or if you have a history of stomach or intestinal disorders. You may not be able to use the medication, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
How should I use clindamycin and tretinoin topical?
Use clindamycin and tretinoin topical exactly as your doctor has prescribed it for you. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects. Do not use this medication for longer than your doctor has prescribed.
Wash your hands before and after applying this medication.
Wash your face with a mild soap or cleanser and pat the skin dry with a clean towel.
Use only a pea-sized amount of clindamycin and tretinoin topical. Apply to your entire face every night at bedtime.
Do not wash your face more than 3 times daily while using this medication. Washing more often or scrubbing your face when you wash it can make your acne worse.
Avoid getting this medication in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin. Use this medication for as many days as it has been prescribed for you even if you think it is not working. Call your doctor if skin irritation becomes severe or if your acne does not improve after several weeks of using this medicine. Store tretinoin topical at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a clindamycin and tretinoin topical overdose may result if you absorb this medicine through your skin by applying too much of it. Symptoms of a clindamycin overdose may include watery or bloody diarrhea.
What should I avoid while using clindamycin and tretinoin topical?
Do not wash the treated area for at least 1 hour after applying tretinoin topical. Avoid the use of other skin products on the treated area for at least 1 hour following application of tretinoin topical.
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Clindamycin and tretinoin topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Your skin may be more sensitive to weather extremes such as cold and wind. Protect your skin with clothing and use a moisturizing cream or lotion as needed.
Clindamycin and tretinoin topical side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have any of these serious side effects:
-
severe redness, burning, stinging, or peeling of treat skin areas; or
-
diarrhea that is watery or bloody.
Continue using this medicine and talk with your doctor if you have any of these less serious side effects:
-
mild itching, stinging, or dryness of treated skin;
-
temporary lightening or darkening of treated skin; or
-
stuffy nose, sore throat, cough.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect clindamycin and tretinoin topical?
Before using clindamycin and tretinoin topical, tell your doctor if you are using any of the following drugs:
-
erythromycin topical (Akne-Mycin, Emcin Clear, Eryderm, Erygel, Erythra-Derm, Ery-Sol, and others); or
-
erythromycin taken by mouth (E.E.S., E-Mycin, Ery-Tab, E-Mycin, Robimycin, and others).
If you are using any of these drugs, you may not be able to use clindamycin and tretinoin topical, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect clindamycin and tretinoin topical. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist has information about clindamycin and tretinoin topical written for health professionals that you may read.
- Your pharmacist has information about clindamycin and tretinoin topical written for health professionals that you may read.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are using, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:46:12 PM.
