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Zarontin

30/06/10

Generic Name: ethosuximide (ETH oh SUX i mide)
Brand Names: Zarontin

What is Zarontin (ethosuximide)?

Ethosuximide is an anti-epileptic medication, also called an anticonvulsant.

Ethosuximide is used alone or in combination with other medications to treat absence seizures (also called “petit mal” seizures) in adults and children.

Ethosuximide may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Zarontin (ethosuximide)?

Ethosuximide can cause a decrease in many types of blood cells (white cells, red cells, platelets). Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, even if these symptoms first occur after you have been using the medication for several months.

Ethosuximide may also cause liver damage. Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes).

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Do not stop taking ethosuximide without first talking to your doctor, even if you feel better. You may have increased seizures if you stop taking ethosuximide suddenly. You will need to use less and less before you stop the medication completely.

Contact your doctor if your seizures get worse or you have them more often while taking ethosuximide.

Carry an ID card or wear a medical alert bracelet stating that you are taking ethosuximide, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking a seizure medication.

What should I discuss with my healthcare provider before taking Zarontin (ethosuximide)?

You should not use this medication if you are allergic to ethosuximide or to other seizure medications.

If you have lupus, liver disease, or kidney disease, you may need a dose adjustment or special tests to safely take ethosuximide.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

FDA pregnancy category C. It is not known whether ethosuximide is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Your name may need to be listed on a pregnancy registry if you use seizure medication during pregnancy. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether the medication had any effect on the baby.

Ethosuximide passes into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 3 years old without the advice of a doctor.

How should I take Zarontin (ethosuximide)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Ethosuximide can cause a decrease in many types of blood cells (white cells, red cells, platelets). This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, including flu-like symptoms. These symptoms may first develop even after you have been using the medication for several months.

To be sure your blood cells do not get too low, your blood may need to be tested on a regular basis while taking ethosuximide. Your kidney and liver function may also need to be tested. Do not miss any scheduled appointments.

Contact your doctor if your seizures get worse or you have them more often while taking ethosuximide.

It is important to use ethosuximide regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store ethosuximide at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, extreme drowsiness, and weak or shallow breathing.

What should I avoid while taking Zarontin (ethosuximide)?

Ethosuximide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Zarontin (ethosuximide) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), mouth sores, unusual weakness;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
joint pain or swelling with fever, swollen glands, muscle aches, chest pain;
patchy skin color, red spots, or a butterfly-shaped skin rash over your cheeks and nose (worsens in sunlight);
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
worsening of seizures.

Less serious side effects may include:

diarrhea;
hiccups, vomiting, weight loss;
swelling in your tongue or gums;
dizziness, drowsiness, nervousness, confusion;
blurred vision;
sleep problems (insomnia);
lack of balance or coordination; or
unusual vaginal bleeding.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zarontin (ethosuximide)?

Before taking ethosuximide, tell your doctor about all other seizure medications you use, especially:

phenobarbital (Luminal, Solfoton); or
phenytoin (Dilantin).

This list is not complete and there may be other drugs that can interact with ethosuximide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about ethosuximide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

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Zantryl

30/06/10

Generic Name: phentermine (FEN ter meen)
Brand Names: Adipex-P, Ionamin, Obenix, Oby-Cap, Teramine, Zantryl

What is Zantryl (phentermine)?

Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.

Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Phentermine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Zantryl (phentermine)?

Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor’s advice.

Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

You may have withdrawal symptoms, such as depression and extreme tiredness, when you stop using phentermine after a long period of use. Do not stop using phentermine suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

What should I discuss with my healthcare provider before taking Zantryl (phentermine)?

Do not take phentermine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take phentermine before the MAO inhibitor has cleared from your body.

Do not take this medication if you are allergic to phentermine or other stimulants, or if you have:

heart disease or high blood pressure;
arteriosclerosis (hardening of the arteries);
an overactive thyroid;
glaucoma;
if you are in an agitated state; or
if you have a history of drug or alcohol abuse.

Before taking phentermine, tell your doctor if you are allergic to any drugs, or if you have:

a thyroid disorder;
anxiety disorder;
diabetes; or
epilepsy or another seizure disorder.

If you have any of these conditions, you may need a dose adjustment or special tests during treatment.

It is not known whether phentermine will harm an unborn baby. Do not take phentermine without telling your doctor if you are pregnant. It is also not known whether phentermine passes into breast milk or if it could harm a nursing baby. Do not take phentermine without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 16 years old without the advice of a doctor. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Phentermine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

How should I take Zantryl (phentermine)?

It is best to take phentermine on an empty stomach before breakfast, or at least 10 to 14 hours before bedtime. Do not take more phentermine for an increased effect. Taking too much of this medication can cause serious, life-threatening side effects. Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Phentermine should be taken only for a short time, such as a few weeks.

Taking high doses of phentermine over long periods of time can cause severe skin problems, sleep problems (insomnia), personality changes, and feeling hyperactive or irritable.

Stop taking phentermine if you have increased hunger or if you otherwise think the medication is not working properly.

You may have withdrawal symptoms when you stop using phentermine after a long period of use. Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Do not take phentermine in the evening because it may cause sleep problems (insomnia).

Store this medication at room temperature away from moisture and heat. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medication. An overdose of phentermine can be fatal.

Overdose symptoms may include confusion, hallucinations, feeling restless or aggressive, nausea, vomiting, diarrhea, stomach pain, irregular heartbeat, tremors, rapid breathing, confusion, hallucinations, feeling light-headed, fainting, or seizure (convulsions).

What should I avoid while taking Zantryl (phentermine)?

Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Zantryl (phentermine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using phentermine and call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
chest pain, fast or uneven heartbeat, feeling like you might pass out;
unusual thoughts or behavior, feeling restless or confused; or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

feeling nervous or anxious;
headache, dizziness, tremors;
trouble sleeping (insomnia);
dry mouth or an unpleasant taste in your mouth;
diarrhea or constipation; or
itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zantryl (phentermine)?

Before taking phentermine, tell your doctor if you are using any of the following drugs:

medicines to treat high blood pressure;
insulin or diabetes medication you take by mouth;
guanadrel (Hylorel), guanethidine (Ismelin);
antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); or
antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

This list is not complete and there may be other drugs that can interact with phentermine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about phentermine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

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Zanosar

30/06/10

Generic Name: streptozocin (STREP toe zoe sin)
Brand Names: Zanosar

What is Zanosar (streptozocin)?

Streptozocin is an antineoplastic medication. Streptozocin interferes with the growth of cancer cells and slows their growth and spread in the body.

Streptozocin is used to treat cancer of the pancreas.

Streptozocin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Zanosar (streptozocin)?

Streptozocin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of streptozocin including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); kidney damage (little or no urine production, blood in the urine); liver problems (changes in blood test results, abdominal pain, yellowing of the skin or eyes, decreased appetite, nausea); decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); severe nausea, vomiting, and diarrhea; secondary cancers; and others. Talk to your doctor about the possible side effects from treatment with streptozocin.

Treatment with streptozocin may cause drowsiness or confusion. Use caution when driving, operating machinery, or performing other hazardous activities if drowsiness or confusion occurs.

What should I discuss with my healthcare provider before using Zanosar (streptozocin)?

Do not use streptozocin without first talking to your doctor if you have

kidney disease;
liver problems;
bleeding or blood clotting problems; or
poor bone marrow function.

The use of streptozocin may be dangerous if you have any of the conditions listed above.

Streptozocin is in the FDA pregnancy category D. This means that streptozocin is known to be harmful to an unborn baby. Do not use streptozocin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with streptozocin if necessary. It is not known whether streptozocin passes into breast milk. Breast-feeding should be avoided during treatment with streptozocin.

How should I use Zanosar (streptozocin)?

Streptozocin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Your doctor will determine the correct amount and frequency of treatment with streptozocin, depending upon the type of cancer being treated and other factors. Talk to your doctor if you have any questions or concerns regarding the treatment schedule.

Streptozocin is usually administered as an intravenous (into a vein) injection.

Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with streptozocin to monitor progress and side effects.

Your healthcare provider will store streptozocin as directed by the manufacturer. If you are storing streptozocin at home, follow the directions provided by your healthcare provider.

What happens if I miss a dose?

Contact your doctor if you miss a dose of streptozocin.

What happens if I overdose?

If an overdose of streptozocin is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Symptoms of a streptozocin overdose tend to be similar to side effects caused by the medication, although often more severe.

What should I avoid while using Zanosar (streptozocin)?

Streptozocin can lower the activity of your immune system making you susceptible to infections. Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with streptozocin. In addition, avoid contact with individuals who have recently been vaccinated with a live vaccine. There is a chance that the virus can be passed on to you.

Treatment with streptozocin may cause drowsiness or confusion. Use caution when driving, operating machinery, or performing other hazardous activities if drowsiness or confusion occurs.

Zanosar (streptozocin) side effects

If you experience any of the following serious side effects from streptozocin, contact your doctor immediately or seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
kidney damage (little or no urine production, blood in the urine);
liver problems (changes in blood test results, abdominal pain, yellowing of the skin or eyes, decreased appetite, nausea);
decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); or
severe nausea, vomiting, loss of appetite, or diarrhea.

In some cases, secondary cancers have been reported to occur during and following treatment with streptozocin. Talk to your doctor about the risks and benefits of this medication.

Other, less serious side effects may be more likely to occur. Continue taking streptozocin and talk to your doctor if you experience:

mild nausea, vomiting, loss of appetite, or diarrhea;
drowsiness;
confusion;
depression; or
swelling, redness, burning, or tenderness at the injection site.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zanosar (streptozocin)?

Do not receive “live” vaccines during treatment with streptozocin. Administration of a live vaccine may be dangerous during treatment with streptozocin.

Other medications may interact with streptozocin. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, during treatment with streptozocin.

Where can I get more information?

Your healthcare provider may have additional information about streptozocin that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

zanamivir

30/06/10

Generic Name: zanamivir (zan AM i vir)
Brand Names: Relenza

What is zanamivir?

Zanamivir is an antiviral medication. It blocks the actions of viruses in your body.

Zanamivir is used to treat flu symptoms caused by influenza virus in patients who have had symptoms for less than 2 days. Zanamivir may also be given to prevent influenza in people who may be exposed but do not yet have symptoms. Zanamivir will not treat the common cold.

Zanamivir may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about zanamivir?

Do not use a nebulizer or ventilator to give zanamivir. Zanamivir inhalation powder should never be mixed with a liquid.

Treatment with zanamivir should start as soon as possible when flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.

Do not use this medication to treat flu symptoms in a child younger than 7 years old. Children as young as 5 may use the medication to prevent flu symptoms. Do not use an inhaled nasal flu vaccine (FluMist) within 2 weeks before or 48 hours after using zanamivir. Zanamivir may interfere with the drug action of FluMist, making the vaccine less effective. Follow your doctor’s instructions. Before using zanamivir, tell your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition. Serious or life-threatening bronchospasm (difficulty breathing) and other effects on the lungs can occur while using zanamivir. Stop using zanamivir and call your doctor at once if you have wheezing or severe breathing problems.

If you have asthma, COPD, or other chronic lung disease, make sure you have a fast-acting inhaled bronchodilator available to treat any serious breathing problems that may occur while using zanamivir. Fast-acting bronchodilators include albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), and pirbuterol (Maxair). Talk with your doctor about which medicine is best for you.

Some people using zanamivir have had rare side effects of confusion, delirium and self-injury. These symptoms have occurred most often in children. It is not known whether zanamivir was the exact cause of these symptoms. However, anyone using zanamivir should be watched closely for signs of confusion or unusual behavior. Call a doctor at once if you or the child using zanamivir has any of these symptoms. Zanamivir should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.

What should I discuss with my healthcare provider before using zanamivir?

Zanamivir should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus.

You should not use this medication if you are allergic to zanamivir or to lactose. Before using zanamivir, tell your doctor if you have asthma, chronic obstructive pulmonary disease (COPD), or any other chronic lung condition. Serious or life-threatening bronchospasm (difficulty breathing) and other effects on the lungs can occur while using zanamivir.

If you are scheduled to use a bronchodilator at the same time as zanamivir, use the inhaler first.

FDA pregnancy category C. It is not known whether zanamivir will harm an unborn baby. However, not receiving this medication to prevent influenza could be harmful to the baby if the mother becomes infected with a disease that zanamivir could prevent. Tell your doctor if you are pregnant. Your doctor will decide whether you should receive zanamivir, especially if you have a high risk of infection with H1N1 influenza (also called “swine” flu). It is not known whether zanamivir passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication to treat flu symptoms in a child younger than 7 years old. Children as young as 5 may use the medication to prevent flu symptoms.

How should I use zanamivir?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Treatment with zanamivir should start as soon as possible when flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.

Zanamivir is packaged in disk-shaped foil packs that contain 4 blisters of medicine. These disks are placed into a device called a DISKHALER that you will use to inhale the medicine. The device opens and loads a blister of zanamivir each time you use the inhaler. The disk device is not to be used with a spacer. Follow the patient instructions provided with the DISKHALER.

Do not use a nebulizer or ventilator to give zanamivir. Zanamivir inhalation powder should never be mixed with a liquid. Do not use any other medicines in the DISKHALER. Always put the cover back on the device when not in use.

To treat flu symptoms: Use 2 inhalations every 12 hours for 5 days. Your doctor may tell you to use two doses on the first day of treatment, spaced at least 2 hours apart. On the following days, the doses should be spaced 12 hours apart. Follow your doctor’s instructions.

To prevent flu symptoms: Use 2 inhalations every 24 hours for 10 to 28 days. Follow your doctor’s instructions.

If you have a chronic respiratory disease such as asthma or COPD and you are scheduled to use an inhaled bronchodilator at the same time as zanamivir, use the inhaled bronchodilator before using zanamivir.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Tell your doctor if your symptoms do not improve, or if they get worse.

Store zanamivir at room temperature away from moisture and heat. Throw away the DISKHALER after your treatment ends.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is within 2 hours of your next scheduled dose. Do not use extra medicine to make up the missed dose.

Call your doctor if you miss several doses.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using zanamivir?

Do not use an inhaled nasal flu vaccine (FluMist) within 2 weeks before or 48 hours after using zanamivir. Zanamivir may interfere with the drug action of FluMist, making the vaccine less effective. Follow your doctor’s instructions.

Zanamivir side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Some people using zanamivir have had rare side effects of confusion, delirium and self-injury. These symptoms have occurred most often in children. It is not known whether zanamivir was the exact cause of these symptoms. However, anyone using zanamivir should be watched closely for signs of confusion or unusual behavior. Call a doctor at once if you or the child using zanamivir has any of these symptoms. Stop using zanamivir and call your doctor at once if you have wheezing or severe breathing problems.

Less serious side effects may include:

headache;
dizziness;
nausea, vomiting, or diarrhea;
infection of your ear, nose, or throat;
stuffy or irritated nose; or
cough or respiratory symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Zanamivir Dosing Information

Usual Adult Dose for Influenza:

10 mg (2 inhalations) inhaled orally twice a day (12 hours apart) for 5 days

If possible, 2 doses should be taken on the first day, provided there are at least 2 hours between the doses.

Usual Adult Dose for Influenza Prophylaxis:

10 mg (2 inhalations) inhaled orally once a day

Duration:
Household setting: 10 days
Community outbreak: 28 days

Usual Pediatric Dose for Influenza:

7 years or older: 10 mg (2 inhalations) inhaled orally twice a day (12 hours apart) for 5 days

If possible, 2 doses should be taken on the first day, provided there are at least 2 hours between the doses.

Usual Pediatric Dose for Influenza Prophylaxis:

5 years or older: 10 mg (2 inhalations) inhaled orally once a day

Duration:
Household setting: 10 days
Community outbreak: 28 days

What other drugs will affect zanamivir?

There may be other drugs that can interact with zanamivir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about zanamivir.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

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Zamicet

30/06/10

Generic Name: acetaminophen and hydrocodone (a SEET a MIN oh fen and hye droe KOE done)
Brand Names: Anexsia, Dolorex Forte, Hycet, Liquicet, Lorcet 10/650, Lorcet Plus, Lortab 10/500, Lortab 2.5/500, Lortab 5/500, Lortab 7.5/500, Lortab Elixir, Maxidone, Norco, Polygesic, Stagesic, Vicodin, Vicodin ES, Vicodin HP, Xodol, Xodol 5, Zamicet, Zydone

What is Zamicet (acetaminophen and hydrocodone)?

Hydrocodone is in a group of drugs called narcotic pain relievers.

Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone.

The combination of acetaminophen and hydrocodone is used to relieve moderate to severe pain.

Acetaminophen and hydrocodone may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Zamicet (acetaminophen and hydrocodone)?

Tell your doctor if you drink more than three alcoholic beverages per day or if you have ever had alcoholic liver disease (cirrhosis). You may not be able to take medication that contains acetaminophen.

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

What should I discuss with my healthcare provider before taking Zamicet (acetaminophen and hydrocodone)?

Do not use this medication if you are allergic to acetaminophen (Tylenol) or hydrocodone. Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Acetaminophen and hydrocodone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

asthma, COPD, sleep apnea, or other breathing disorders;
liver or kidney disease;
a history of head injury or brain tumor;
low blood pressure;
a stomach or intestinal disorder;
underactive thyroid;
Addison’s disease or other adrenal gland disorder;
curvature of the spine;
mental illness; or
a history of drug or alcohol addiction.

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby, but it could cause breathing problems or addiction/withdrawal symptoms in a newborn. Before you take acetaminophen and hydrocodone, tell your doctor if you are pregnant or plan to become pregnant during treatment. Acetaminophen and hydrocodone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Zamicet (acetaminophen and hydrocodone)?

Take this medication exactly as it was prescribed for you. Do not take it in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

An overdose of acetaminophen can cause serious harm to your liver. The maximum amount of acetaminophen for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. One acetaminophen and hydrocodone tablet may contain up to 750 mg of acetaminophen. Know the amount of acetaminophen in the specific product you are taking.

Measure the liquid form of this medication with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking acetaminophen and hydrocodone. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor. You may have withdrawal symptoms when you stop using acetaminophen and hydrocodone after using it over a long period of time. Do not stop using this medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

This medication can cause you to have unusual results with certain urine tests. Tell any doctor who treats you that you are using acetaminophen and hydrocodone.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using acetaminophen and hydrocodone. You may need to stop using the medicine for a short time.

Store acetaminophen and hydrocodone at room temperature away from moisture and heat.

Keep track of how many tablets have been used from each new bottle of this medicine. Hydrocodone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Since acetaminophen and hydrocodone is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of acetaminophen and hydrocodone can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include extreme drowsiness, pinpoint pupils, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing

What should I avoid while taking Zamicet (acetaminophen and hydrocodone)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not use any other cold, allergy, pain, or sleep medication without first asking your doctor or pharmacist. Acetaminophen (sometimes abbreviated as “APAP”) is contained in many combination medicines. If you use certain products together you may accidentally use too much acetaminophen. Read the label of any other medicine you are using to see if it contains acetaminophen or APAP. Avoid drinking alcohol while taking acetaminophen and hydrocodone. Alcohol may increase your risk of liver damage while taking acetaminophen. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, antidepressants, or seizure medication can add to sleepiness caused by hydrocodone, or could slow your breathing. Tell your doctor if you need to use any of these other medicines while you are taking acetaminophen and hydrocodone.

Zamicet (acetaminophen and hydrocodone) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

shallow breathing, slow heartbeat;
feeling light-headed, fainting;
confusion, fear, unusual thoughts or behavior;
seizure (convulsions);
problems with urination; or
nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

feeling anxious, dizzy, or drowsy;
mild nausea, vomiting, upset stomach, constipation;
headache, mood changes;
blurred vision;
ringing in your ears; or
dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zamicet (acetaminophen and hydrocodone)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others;
an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), glycopyrrolate (Robinul), mepenzolate (Cantil), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
a bronchodilator such as ipratropium (Atrovent) or tiotropium (Spiriva); or
irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

This list is not complete and there may be other drugs that can interact with acetaminophen and hydrocodone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about acetaminophen and hydrocodone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

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zaleplon

30/06/10

Generic Name: zaleplon (ZAH le plon)
Brand Names: Sonata

What is zaleplon?

Zaleplon is a sedative, also called a hypnotic. It affects chemicals in your brain that may become unbalanced and cause sleep problems (insomnia).

Zaleplon is used to treat insomnia. This medication causes relaxation to help you fall asleep and stay asleep.

Zaleplon may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about zaleplon?

Zaleplon may cause a severe allergic reaction. Stop taking zaleplon and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Zaleplon will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 4 hours to dedicate to sleeping.

Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking zaleplon and talk with your doctor about another treatment for your sleep disorder.

Zaleplon can cause side effects that may impair your thinking or reactions. You may still feel sleepy the morning after taking the medication. Until you know how this medication will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert. Do not drink alcohol while you are taking zaleplon. It can increase some of the side effects of zaleplon, including drowsiness. Zaleplon may be habit-forming and should be used only by the person it was prescribed for. Zaleplon should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

You may have withdrawal symptoms if you stop taking zaleplon after taking it over several days in a row. Do not stop taking zaleplon suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

What should I discuss with my healthcare provider before taking zaleplon?

Zaleplon will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 4 hours to dedicate to sleeping.

Do not use this medication if you are allergic to zaleplon.

Before taking zaleplon, tell your doctor if you are allergic to any drugs, or if you have:

liver disease;
sleep apnea (breathing stops while you are asleep);
lung disease such as asthma, bronchitis, emphysema, or chronic obstructive pulmonary disease (COPD);
a history of depression, mental illness, or suicidal thoughts; or
a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take zaleplon.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zaleplon can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of zaleplon may be stronger in older adults. Accidental falls are common in elderly patients who take sedatives. Use caution to avoid falling or accidental injury while you are taking zaleplon.

Zaleplon may be habit-forming and should be used only by the person it was prescribed for. Zaleplon should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

How should I take zaleplon?

Take zaleplon only if you are able to get a full night’s sleep before you must be active again. Never take this medication during your normal waking hours, unless you have at least 4 hours to dedicate to sleeping.

Take zaleplon with a full glass of water.

Avoid taking zaleplon within 1 hour after eating a high-fat or heavy meal. This will make it harder for your body to absorb the medication.

Zaleplon is for short-term use only. Tell your doctor if your insomnia symptoms do not improve, or if they get worse after using this medication for 7 to 10 nights in a row. Do not take zaleplon for longer than 2 weeks without your doctor’s advice.

Store zaleplon at room temperature away from moisture and heat. Keep track of how many capsules have been used from each new bottle of this medicine. Zaleplon is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

See also: Zaleplon dosage in more detail

What happens if I miss a dose?

Since zaleplon is usually taken as needed, you may not be on a dosing schedule. Never take this medication if you do not have at least 4 hours to sleep before being active again. Do not take extra medicine to make up a missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include sleepiness, confusion, shallow breathing, feeling light-headed, fainting, or coma.

What should I avoid while taking zaleplon?

Zaleplon can cause side effects that may impair your thinking or reactions. You may still feel sleepy the morning after taking the medication. Until you know how this medication will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert. Do not drink alcohol while you are taking zaleplon. It can increase some of the side effects of zaleplon, including drowsiness. Do not take other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxants, and medicine for depression or anxiety).

Avoid taking zaleplon during travel, such as to sleep on an airplane. You may be awakened before the effects of the medication have worn off. Amnesia (forgetfulness) is more common if you do not get at least 4 hours of sleep after taking zaleplon.

Zaleplon side effects

Zaleplon may cause a severe allergic reaction. Stop taking zaleplon and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using zaleplon and call your doctor at once if you have any of these serious side effects:

aggression, agitation, changes in behavior;
thoughts of hurting yourself; or
hallucinations (hearing or seeing things).

Less serious side effects may include:

day-time drowsiness, dizziness, “hangover” feeling;
problems with memory or concentration;
numbness or tingling;
anxiety, depression, nervous feeling;
problems with vision;
headache;
nausea, stomach pain, loss of appetite, constipation;
dry mouth;
increased menstrual pain (cramps);
back pain, joint or muscle pain; or
mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Zaleplon Dosing Information

Usual Adult Dose for Insomnia:

5 to 20 mg orally immediately before bedtime or after the patient has gone to bed and has experienced difficulty falling asleep.

Doses above 20 mg have not been adequately evaluated and are not recommended.

Usual Geriatric Dose for Insomnia:

Elderly patients and debilitated patients appear to be more sensitive to the effects of hypnotics, and respond to 5 mg of zaleplon. Doses over 10 mg are not recommended.

What other drugs will affect zaleplon?

Before taking zaleplon, tell your doctor if you are taking any of the following drugs:

cimetidine (Tagamet);
thioridazine (Mellaril);
promethazine (Phenergan, Promacot);
cyclosporine (Gengraf, Neoral, Sandimmune);
rifampin (Rifadin, Rifater, Rifamate, Rimactane);
antibiotics such as azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin), itraconazole (Sporanox), or ketoconazole (Nizoral);
antidepressants such as imipramine (Janimine, Tofranil), fluoxetine (Prozac, Sarafem), or sertraline (Zoloft); or
narcotic pain medications, muscle relaxers, seizure medications, or anti-anxiety medications.

This list is not complete and there may be other drugs that can interact with zaleplon. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about zaleplon.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

zalcitabine

30/06/10

Generic Name: zalcitabine (zal SITE ta been)
Brand Names: Hivid

What is zalcitabine?

Zalcitabine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.

Zalcitabine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Zalcitabine is not a cure for HIV or AIDS.

Zalcitabine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about zalcitabine?

Zalcitabine may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Call your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal. Zalcitabine can also cause severe or life-threatening effects on your liver or pancreas. Call your doctor at once if you have any of these symptoms while taking zalcitabine: severe pain in your upper stomach spreading to your back, fast heart rate, nausea and vomiting, diarrhea, loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Before taking this medication, tell your doctor if you have kidney disease, liver disease, a history of pancreatitis, or if you have used a medicine similar to zalcitabine in the past, such as abacavir (Ziagen), didanosine (Videx), lamivudine (Epivir), stavudine (Zerit), tenofovir (Viread), or zidovudine (Retrovir).

HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.

Taking zalcitabine will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.

What should I discuss with my healthcare provider before taking zalcitabine?

Do not use this medication if you are allergic to zalcitabine. Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease (including hepatitis B);
a history of pancreatitis; or
if you have used a medicine similar to zalcitabine in the past, such as abacavir (Ziagen), didanosine (Videx), lamivudine (Epivir), stavudine (Zerit), tenofovir (Viread), or zidovudine (Retrovir).

If you have any of the conditions listed above, you may not be able to use zalcitabine or you may need a dosage adjustment or special tests during treatment.

Zalcitabine may cause lactic acidosis (the build up of lactic acid in the body). Lactic acidosis symptoms can start slowly and gradually get worse. Symptoms include unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, nausea, vomiting, stomach pain, and numbness or cold feeling in your arms or legs. Call your doctor at once if you have any of these symptoms, even if they are only mild. Early signs of lactic acidosis generally get worse over time and this condition can be fatal. Zalcitabine can also cause severe or life-threatening effects on your liver or pancreas. Call your doctor at once if you have any of these symptoms while taking zalcitabine: severe pain in your upper stomach spreading to your back, fast heart rate, nausea and vomiting, diarrhea, loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to the baby if the mother is not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection while you are pregnant.

Your name may need to be listed on an antiviral pregnancy registry when you start using zalcitabine. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether zalcitabine had any effect on the baby.

You should not breast-feed while you are using zalcitabine. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.

How should I take zalcitabine?

Take zalcitabine with a full glass of water.

Zalcitabine is usually taken every 8 hours, but if you have kidney disease you may need to take it every 12 or 24 hours. Follow your doctor’s instructions.

Take zalcitabine on an empty stomach, at least 1 hour before or 2 hours after a meal. This will make it easier for your body to absorb the medicine.

It is important to use zalcitabine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

Store zalcitabine in a tightly closed container at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a zalcitabine overdose may include nausea or drowsiness.

What should I avoid while taking zalcitabine?

Avoid using antacids without your doctor’s advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb zalcitabine.

Avoid drinking alcohol while taking zalcitabine. Alcohol may increase the risk of damage to the pancreas and/or liver.

Zalcitabine side effects

Stop using zalcitabine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these other serious side effects:

liver damage – nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
lactic acidosis – muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, nausea with vomiting, and fast or uneven heart rate;
pancreatitis – severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
peripheral neuropathy – numbness, tingling, or pain in your hands or feet;
easy bruising or bleeding, unusual weakness, pale skin;
white patches or sores inside your mouth or on your lips;
seizure (convulsions);
fever, chills, body aches, flu symptoms; or
any other signs of new infection.

Less serious side effects may be more likely to occur, such as:

mild nausea, vomiting, stomach pain, diarrhea, constipation;
headache, tired feeling;
skin rash; or
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Zalcitabine Dosing Information

Usual Adult Dose for HIV Infection:

0.75 mg orally every 8 hours.

What other drugs will affect zalcitabine?

Before taking zalcitabine, tell your doctor if you are using any of the following drugs:

cimetidine (Tagamet);
foscarnet (Foscavir);
nitrofurantoin (Furadantin, Macrobid, Macrodantin);
probenecid (Benemid);
amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet);
an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), netilmicin (Netromycin), streptomycin, tobramycin (Nebcin, Tobi); or
other drugs that can affect the pancreas, such as asparaginase (Elspar), azathioprine (Imuran), estrogens (birth control or hormone replacement), furosemide (Lasix), methyldopa (Aldomet), pentamidine (Nebupent), sulindac, valproic acid (Depakene), diuretics (water pills), sulfa drugs, or tetracycline antibiotics.

If you are using any of these drugs, you may not be able to use zalcitabine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect zalcitabine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about zalcitabine written for health professionals that you may read.

What does my medication look like?

Zalcitabine is available with a prescription under the brand name Hivid. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Hivid 0.375 mg–oval, beige, film-coated tablets
Hivid 0.750 mg–oval, gray, film-coated tablets

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

Zagam

30/06/10

Generic Name: sparfloxacin (spar FLOX a sin)
Brand Names: Zagam, Zagam Respipac

What is Zagam (sparfloxacin)?

Sparfloxacin has been withdrawn from the U.S. market.

Sparfloxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body.

Sparfloxacin is used to treat various types of bacterial infections.

Sparfloxacin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Zagam (sparfloxacin)?

Sparfloxacin has been withdrawn from the U.S. market.

Take all of the sparfloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Take sparfloxacin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent sparfloxacin crystals from forming in the urine. Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic.

What should I discuss with my healthcare provider before taking Zagam (sparfloxacin)?

Before taking this medication, tell your doctor if you have

kidney disease;
any kind of heart disease or heart problem; or
seizures or epilepsy.

You may not be able to take sparfloxacin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Sparfloxacin is in the FDA pregnancy category C. This means that it is not known whether sparfloxacin will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Sparfloxacin passes into breast milk and may harm a nursing infant. It may affect bone development. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Sparfloxacin is not approved for use by children younger than 12 years of age. Sparfloxacin may interfere with bone development.

How should I take Zagam (sparfloxacin)?

Take sparfloxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent the formation of sparfloxacin crystals in your urine.

Sparfloxacin may be taken with or without food.

Take sparfloxacin at evenly spaced intervals. Follow your doctor’s instructions.

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic. Take all of the sparfloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention.

The most common symptom of a sparfloxacin overdose is irregular or slow heartbeats.

What should I avoid while taking Zagam (sparfloxacin)?

Avoid prolonged exposure to sunlight. Sparfloxacin increases the sensitivity of the skin to sunlight, and a severe sunburn may result. If sun exposure is unavoidable, wear protective clothing and sunscreen. Call your doctor if you experience severe burning, redness, itching, rash, or swelling after exposure to the sun. Use caution when driving, operating machinery, or performing other hazardous activities. Sparfloxacin may cause dizziness. If you experience dizziness, avoid these activities.

Zagam (sparfloxacin) side effects

If you experience any of the following serious side effects, stop taking sparfloxacin and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
irregular heartbeats;
chest pain, chest discomfort, shortness of breath, or swelling of your legs or feet;
severe dizziness;
seizures;
confusion or hallucinations;
liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
muscle or joint pain.

If you experience any of the following less serious side effects, continue taking sparfloxacin and talk to your doctor:

nausea, vomiting, diarrhea, or constipation;
headache, lightheadedness, or drowsiness;
ringing in the ears; or
increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zagam (sparfloxacin)?

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic. Do not take sparfloxacin without first talking to your doctor if you are taking any of the following drugs:

the heart medicines amiodarone (Cordarone), disopyramide (Norpace), quinidine (Cardioquin, Quinidex, Quinaglute, others), procainamide (Procan SR, Pronestyl), sotalol (Betapace), and bepridil (Vascor);
terfenadine (Seldane, Seldane-D) or astemizole (Hismanal);
a tricyclic antidepressant including amitriptyline (Elavil, Endep), amoxapine (Asendin), imipramine (Tofranil), nortriptyline (Pamelor), doxepin (Sinequan), and others;
a phenothiazine including chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), and others;
erythromycin (E-Mycin, Ery-Tab, E.E.S., others); or
cisapride (Propulsid).

Sparfloxacin and the drugs listed above may affect the rhythm of your heartbeats. You may not be able to take sparfloxacin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with sparfloxacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about sparfloxacin written for health professionals that you may read.

What does my medication look like?

Sparfloxacin has been withdrawn from the U.S. market.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

Zagam Respipac

30/06/10

Generic Name: sparfloxacin (spar FLOX a sin)
Brand Names: Zagam, Zagam Respipac

What is Zagam Respipac (sparfloxacin)?

Sparfloxacin has been withdrawn from the U.S. market.

Sparfloxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body.

Sparfloxacin is used to treat various types of bacterial infections.

Sparfloxacin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Zagam Respipac (sparfloxacin)?

Sparfloxacin has been withdrawn from the U.S. market.

What should I discuss with my healthcare provider before taking Zagam Respipac (sparfloxacin)?

Before taking this medication, tell your doctor if you have

kidney disease;
any kind of heart disease or heart problem; or
seizures or epilepsy.

You may not be able to take sparfloxacin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

How should I take Zagam Respipac (sparfloxacin)?

Take sparfloxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent the formation of sparfloxacin crystals in your urine.

Sparfloxacin may be taken with or without food.

Take sparfloxacin at evenly spaced intervals. Follow your doctor’s instructions.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention.

The most common symptom of a sparfloxacin overdose is irregular or slow heartbeats.

What should I avoid while taking Zagam Respipac (sparfloxacin)?

Zagam Respipac (sparfloxacin) side effects

If you experience any of the following serious side effects, stop taking sparfloxacin and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
irregular heartbeats;
chest pain, chest discomfort, shortness of breath, or swelling of your legs or feet;
severe dizziness;
seizures;
confusion or hallucinations;
liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or
muscle or joint pain.

If you experience any of the following less serious side effects, continue taking sparfloxacin and talk to your doctor:

nausea, vomiting, diarrhea, or constipation;
headache, lightheadedness, or drowsiness;
ringing in the ears; or
increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Zagam Respipac (sparfloxacin)?

Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic. Do not take sparfloxacin without first talking to your doctor if you are taking any of the following drugs:

the heart medicines amiodarone (Cordarone), disopyramide (Norpace), quinidine (Cardioquin, Quinidex, Quinaglute, others), procainamide (Procan SR, Pronestyl), sotalol (Betapace), and bepridil (Vascor);
terfenadine (Seldane, Seldane-D) or astemizole (Hismanal);
a tricyclic antidepressant including amitriptyline (Elavil, Endep), amoxapine (Asendin), imipramine (Tofranil), nortriptyline (Pamelor), doxepin (Sinequan), and others;
a phenothiazine including chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine (Mellaril), and others;
erythromycin (E-Mycin, Ery-Tab, E.E.S., others); or
cisapride (Propulsid).

Drugs other than those listed here may also interact with sparfloxacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about sparfloxacin written for health professionals that you may read.

What does my medication look like?

Sparfloxacin has been withdrawn from the U.S. market.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

zafirlukast

30/06/10

Generic Name: zafirlukast (za FIR loo cast)
Brand Names: Accolate

What is zafirlukast?

Zafirlukast is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Zafirlukast is used to treat and prevent asthma attacks in adults and children as young as 5 years old.

Do not give this medication to a child without a doctor’s advice.

Zafirlukast may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about zafirlukast?

Do not use zafirlukast to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. It may take up to several weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after several weeks of treatment.

Call your doctor right away if you feel that this medicine is not working as well as usual, or if it makes your condition worse. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor.

What should I discuss with my healthcare provider before taking zafirlukast?

Do not use this medication if you are allergic to zafirlukast.

Before using zafirlukast, tell your doctor if you are allergic to any drugs (especially aspirin), or if you have liver disease. You may not be able to use zafirlukast, or you may need dosage adjustments or special tests during treatment.

The chewable tablet form of this medication may contain up to 0.842 milligrams of phenylalanine. Talk to your doctor before using this form of zafirlukast if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Zafirlukast can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take zafirlukast?

Zafirlukast is usually taken once daily in the evening for prevention of asthma or allergy symptoms. Follow your doctor’s instructions.

Take zafirlukast on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not use zafirlukast to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use only a fast-acting inhalation medication to treat an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks. For best results, keep using zafirlukast as directed. Talk with your doctor if your symptoms do not improve after several weeks of treatment.

Asthma is often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor, even if you have no asthma symptoms.

Store zafirlukast at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include skin rash and upset stomach.

What should I avoid while taking zafirlukast?

Avoid situations or activities that may trigger an asthma attack.

Zafirlukast side effects

worsening asthma symptoms;
mood or behavior changes, anxiety, depression, or thoughts about suicide or hurting yourself;
skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or
nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

headache;
nausea, vomiting, diarrhea, stomach pain;
weakness;
dizziness;
muscle pain; or
fever, sore throat, cold symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Zafirlukast Dosing Information

Usual Adult Dose for Asthma — Maintenance:

20 mg orally twice a day, 1 hour before or 2 hours after meals.

Usual Pediatric Dose for Asthma — Maintenance:

5 years to 11 years:

10 mg orally twice a day, 1 hour before or 2 hours after meals.

> 12 years:

20 mg orally twice a day, 1 hour before or 2 hours after meals.

What other drugs will affect zafirlukast?

Before using zafirlukast, tell your doctor if you are using any of the following drugs:

aspirin;
a blood thinner such as warfarin (Coumadin);
tolbutamide (Orinase);
erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin);
theophylline (Elixophyllin, Respbid, Slo-Bid, TheoDur, and others);
carbamazepine (Carbatrol, Tegretol); or
phenytoin (Dilantin).

This list is not complete and there may be other drugs that can interact with zafirlukast. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about zafirlukast.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,Z

Comments (0)

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Drugs & Medications:A-Z

Recent Posts

Blogroll

30/06/10

What is Zarontin (ethosuximide)?

What is the most important information I should know about Zarontin (ethosuximide)?

What should I discuss with my healthcare provider before taking Zarontin (ethosuximide)?

How should I take Zarontin (ethosuximide)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Zarontin (ethosuximide)?

Zarontin (ethosuximide) side effects

What other drugs will affect Zarontin (ethosuximide)?

Where can I get more information?

30/06/10

What is Zantryl (phentermine)?

What is the most important information I should know about Zantryl (phentermine)?

What should I discuss with my healthcare provider before taking Zantryl (phentermine)?

How should I take Zantryl (phentermine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Zantryl (phentermine)?

Zantryl (phentermine) side effects

What other drugs will affect Zantryl (phentermine)?

Where can I get more information?

30/06/10

What is Zanosar (streptozocin)?

What is the most important information I should know about Zanosar (streptozocin)?

What should I discuss with my healthcare provider before using Zanosar (streptozocin)?

How should I use Zanosar (streptozocin)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using Zanosar (streptozocin)?

Zanosar (streptozocin) side effects

What other drugs will affect Zanosar (streptozocin)?

Where can I get more information?

30/06/10

What is zanamivir?

What is the most important information I should know about zanamivir?

What should I discuss with my healthcare provider before using zanamivir?

How should I use zanamivir?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using zanamivir?

Zanamivir side effects

Zanamivir Dosing Information

What other drugs will affect zanamivir?

Where can I get more information?

30/06/10

What is Zamicet (acetaminophen and hydrocodone)?

What is the most important information I should know about Zamicet (acetaminophen and hydrocodone)?

What should I discuss with my healthcare provider before taking Zamicet (acetaminophen and hydrocodone)?

How should I take Zamicet (acetaminophen and hydrocodone)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Zamicet (acetaminophen and hydrocodone)?

Zamicet (acetaminophen and hydrocodone) side effects

What other drugs will affect Zamicet (acetaminophen and hydrocodone)?

Where can I get more information?

30/06/10

What is zaleplon?

What is the most important information I should know about zaleplon?

What should I discuss with my healthcare provider before taking zaleplon?

How should I take zaleplon?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking zaleplon?

Zaleplon side effects

Zaleplon Dosing Information

What other drugs will affect zaleplon?

Where can I get more information?

30/06/10

What is zalcitabine?

What is the most important information I should know about zalcitabine?

What should I discuss with my healthcare provider before taking zalcitabine?

How should I take zalcitabine?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking zalcitabine?

Zalcitabine side effects