How do they define drug abuse? This addiction, also known as substance abuse, means frequently repeated consumation of a drug aimed at getting into euphoria or escaping from problems in reality. Drug abusers (addicted people) continue to use drugs even if they are aware of negative consequences. An abuser is seldom able to quit himself/herself, without help.

Not all drugs are illegal. The most widely known drug abuse facts involve illegal drugs such as heroin or marijuana. But they may also involve substances that are easily and legally purchased in a store and somehow improperly used: for example, inhalants such as glue, or prescription drugs such as vicodin or ketonal.

Probably the most important drug abuse fact is that, whatever the drug of choice, this drug has a harmful, disruptive influence upon the abuser’s body and soul. Drug abuse destroys a person’s relations with surrounding people and ability to perform usual daily responsibilities. It is essential to know that drug abuse always leads to poor physical and mental health.

Another important fact about drug abuse is that most drug abusers apparently are unable to understand that they develop a drug dependency. They are sure that they can easily quit if they want to. Though, unfortunately, it is not so.

Drug addiction can be physical, psychological, or both. “Heavy” drugs always create both kinds of dependency. Physical addiction leads to “withdrawal” symptoms which the abuser has to suffer when he/she stops taking the drug for some time. Psychological addiction leads to the state of abuser’s mind when he/she becomes unable to to maintain feelings of pleasure, joy, confidence without drugs.

Drug abuse also frequently leads to drug-related crimes. People who have lack of money may sell things which belong to their family and friends, steal, or rob in order to get enough money for purchasing drugs.

I want to make a positive testimonial on cefadroxil tablets and capsules (they have a trade name Duricef®). I had a returning painful urinary tract infectional disease. There was an inflammation, resulting in itching, pains and other problems. At first my doctor prescribed me a mild antibiotic, but this did not cure the infection to the end, and it returned. So we needed a more powerful remedy. CEFADROXIL (Duricef®) is a new, advanced cephalosporin antibiotic which effectively cures  many kinds of infections including dermatological infections, infections of ears, respiratory tract, sinuses, and urinary tract infections.
At first, I was taking generic cefadroxil (Duricef®) tablets, afterwards I bought capsules (I liked them better than tablets). My doctor told me to swallow medicine dozes with a glass of water, several times a day, at regular intervals of at least 4 to 6 hours between doses. As far as I have intestinal problems (colitis), the doctor said it’s better to take Duricef with food. I liked capsules more than tablets because they seem to have a milder action on my stomach and don’t upset it.
I finished the full course prescribed by my doctor, and my condition was perfect! Actually, I felt better after three days already, but I was warned not to stop taking Duricef until course ended. I had some unusual weakness and fatigue during the course, but my doctor said these are normal side effects for this medicine. All in all, I liked it very much.

Generic Name: Carbetapentane/Diphenhydramine/Phenylephrine (car-beta-PEN-tane/dye-fen-HYE-dra-meen/fen-ill-EF-rin)
Brand Name: D-Tann CT and Dytan-CS

Dytan-CS Suspension is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Dytan-CS Suspension is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Dytan-CS Suspension if:

• you are allergic to any ingredient in Dytan-CS Suspension
• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
• you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dytan-CS Suspension:

Some medical conditions may interact with Dytan-CS Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat
• if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid
• if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Dytan-CS Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), cathechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Dytan-CS Suspension may be increased
• Digoxin or droxidopa because risk of irregular heartbeat or heart attack may be increased
• Bromocriptine because side effects ma y be increased by Dytan-CS Suspension
• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Dytan-CS Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dytan-CS Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dytan-CS Suspension:

Use Dytan-CS Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dytan-CS Suspension may be taken with or without food.
• Shake well before using.
• Use a measuring dose marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Dytan-CS Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dytan-CS Suspension.

Important safety information:

• Dytan-CS Suspension may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dytan-CS Suspension. Using Dytan-CS Suspension alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Do not take diet or appetite control medicines while you are taking Dytan-CS Suspension without checking with your doctor.
• Dytan-CS Suspension contains diphenhydramine and phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains diphenhydramine or phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.
• Do NOT exceed the recommended dose or take Dytan-CS Suspension for longer than prescribed without checking with your doctor.
• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
• Dytan-CS Suspension may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Dytan-CS Suspension. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• If you are scheduled for allergy skin testing, do not take Dytan-CS Suspension for several days before the test because it may decrease your response to the skin tests.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Dytan-CS Suspension.
• Use Dytan-CS Suspension with caution in the ELDERLY because they may be more sensitive to its effects.
• Caution is advised when using Dytan-CS Suspension in CHILDREN because they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Dytan-CS Suspension, discuss with your doctor the benefits and risks of using Dytan-CS Suspension during pregnancy. It is unknown if Dytan-CS Suspension is excreted in breast milk. Do not breast-feed while taking Dytan-CS Suspension.

Possible side effects of Dytan-CS Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Dytan-CS Suspension:

Store Dytan-CS Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dytan-CS Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Dytan-CS Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Dytan-CS Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dytan-CS Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: diphenhydramine and phenylephrine (DYE fen HYE dra meenand FEN il EFF rin)
Brand Names: Alahist LQ, Aldex-CT, Children’s Triacting Night Time, D-Tann, Dimetapp Nighttime Cold & Congestion, Diphenmax D, Dytan-D, PediaCare Children’s Allergy & Cold, Robitussin Night Time Cough & Cold, Robitussin Night Time Cough & Cold Children’s, Robitussin Night Time Cough & Cold Pediatric, Triaminic Night Time Cold & Cough

What is Dytan-D (diphenhydramine and phenylephrine)?

Diphenhydramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of diphenhydramine and phenylephrine is used to treat runny or stuffy nose, sneezing, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Diphenhydramine and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Dytan-D (diphenhydramine and phenylephrine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

What should I discuss with my healthcare provider before taking Dytan-D (diphenhydramine and phenylephrine)?

You should not use this medication if you are allergic to diphenhydramine or phenylephrine.

Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have:

• asthma;

• heart disease or high blood pressure;

• diabetes;

• a thyroid disorder;

• glaucoma;

• kidney disease;

• an enlarged prostate; or

• problems with urination.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Dytan-D (diphenhydramine and phenylephrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Make sure you chew the chewable tablet before you swallow it.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Dytan-D (diphenhydramine and phenylephrine)?

Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by diphenhydramine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Dytan-D (diphenhydramine and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heartbeat;

• confusion, hallucinations, unusual thoughts or behavior;

• urinating less than usual or not at all;

• severe dizziness, anxiety, restless feeling, or nervousness;

• easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;

• increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure); or

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

• blurred vision;

• dry mouth;

• nausea, stomach pain, constipation;

• dizziness, drowsiness;

• problems with memory or concentration;

• ringing in your ears;

• mild loss of appetite;

• warmth, tingling, or redness under your skin;

• feeling excited or restless;

• sleep problems (insomnia); or

• skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dytan-D (diphenhydramine and phenylephrine)?

Tell your doctor about all other medications you use, especially:

• medicines to treat high blood pressure;

• a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others;

• antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others; or

• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

This list is not complete and there may be other drugs that can interact with diphenhydramine and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine and phenylephrine.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.07. Revision Date: 11/17/2009 2:04:01 PM.

Generic Name: Diphenhydramine/Phenylephrine (dye-fen-HYE-dra-meen/fen-ill-EF-rin)
Brand Name: Examples include D-Tann and Pediatex-CT

Dytan-D Chewable Tablets are used for:

Temporarily relieving symptoms of hay fever, allergies, or the common cold, including nasal congestion, runny nose, sneezing, itching of the nose and throat, and itchy/watery eyes. It may also be used for other conditions as determined by your doctor.

Dytan-D Chewable Tablets are an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Dytan-D Chewable Tablets if:

• you are allergic to any ingredient in Dytan-D Chewable Tablets
• you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days
• you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dytan-D Chewable Tablets:

Some medical conditions may interact with Dytan-D Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat
• if you have a history of glaucoma; high blood pressure; diabetes; heart problems; ulcers; stroke; asthma; an overactive thyroid; seizures; a blockage of the stomach, bowel, or bladder; trouble breathing when you sleep; trouble sleeping; lung problems (eg, emphysema); the blood disease porphyria; or an enlarged prostate or other prostate problems; adrenal gland problems; blood vessel problems; or if you have difficulty urinating

Some MEDICINES MAY INTERACT with Dytan-D Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially if any of the following apply to you:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), indomethacin, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects such as severe headache, high blood pressure, or high fever may occur
• Bromocriptine or sodium oxybate (GHB) because the risk of side effects or toxic effects may be increased by Dytan-D Chewable Tablets
• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Dytan-D Chewable Tablets.
• Digoxin or droxidopa because side effects such as irregular heartbeat or heart attack may occur
• Urinary alkalinizers (eg, sodium bicarbonate) because the side effects of Dytan-D Chewable Tablets may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dytan-D Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dytan-D Chewable Tablets:

Use Dytan-D Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dytan-D Chewable Tablets may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Chew thoroughly before swallowing.
• If you miss a dose of Dytan-D Chewable Tablets and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dytan-D Chewable Tablets.

Important safety information:

• Dytan-D Chewable Tablets may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dytan-D Chewable Tablets. Using Dytan-D Chewable Tablets alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Dytan-D Chewable Tablets. Dytan-D Chewable Tablets will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Contact your health care provider if symptoms last for more than 7 days or are accompanied by a fever.
• Diabetes patients – Dytan-D Chewable Tablets may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
• Dytan-D Chewable Tablets contains phenylephrine and diphenhydramine. Before you begin taking any new prescription or nonprescription medicine, including medicine used on the skin, read the ingredients to see if it also contains phenylephrine or diphenhydramine. If it does, or if you are uncertain if it does, contact your doctor or pharmacist.
• If you are scheduled for allergy skin testing, do not take Dytan-D Chewable Tablets for several days before the test because it may decrease your response to the skin tests.
• Do not take diet or appetite control medicines while you are taking Dytan-D Chewable Tablets without checking with your doctor.
• Do not exceed the recommended dose or take Dytan-D Chewable Tablets for longer than prescribed without checking with your doctor.
• If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Dytan-D Chewable Tablets.
• Use Dytan-D Chewable Tablets with caution in the ELDERLY because they may be more sensitive to its effects.
• Dytan-D Chewable Tablets are not recommended for use in NEWBORNS. Safety and effectiveness have not been confirmed.
• Different products may have different dosing instructions for CHILDREN on the package labeling. Follow the dosing instructions provided on the package labeling or by your doctor. If you are unsure of what dose to give a child, check with your doctor.
• Caution is advised when using Dytan-D Chewable Tablets in CHILDREN because they may be more sensitive to its effects, especially excitability.
• PREGNANCY AND BREAST-FEEDING: If you become pregnant while taking Dytan-D Chewable Tablets, discuss with your doctor the benefits and risks of using Dytan-D Chewable Tablets during pregnancy. If you are or will be breast-feeding while you are using Dytan-D Chewable Tablets, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Dytan-D Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability (especially in children); headache; loss of appetite; nausea; nervousness; restlessness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased coordination; difficulty urinating; fast or irregular heartbeat; fever; hallucinations; seizure; severe dizziness and drowsiness; severe nervousness, anxiety, or restlessness; tremors; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include bluish-colored skin; difficulty breathing; dilated pupils; fast or irregular heartbeat; fever; flushing; hallucinations; mental or mood changes; seizures; severe drowsiness or dizziness; severe excitability; severe nausea or vomiting; sweating; tremors.

Proper storage of Dytan-D Chewable Tablets:

Store Dytan-D Chewable Tablets at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dytan-D Chewable Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Dytan-D Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.
• Dytan-D Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dytan-D Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Diphenhydramine/Phenylephrine (dye-fen-HYE-dra-meen/fen-ill-EF-rin)
Brand Name: Examples include D-Tann and Dytan-D

Dytan-D Suspension is used for:

Temporarily relieving symptoms of hay fever, allergies, or the common cold, including nasal congestion, runny nose, sneezing, itching of the nose and throat, and itchy/watery eyes. It may also be used for other conditions as determined by your doctor.

Dytan-D Suspension is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Dytan-D Suspension if:

• you are allergic to any ingredient in Dytan-D Suspension
• you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days
• you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dytan-D Suspension:

Some medical conditions may interact with Dytan-D Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat
• if you have a history of glaucoma; high blood pressure; diabetes; heart problems; ulcers; stroke; asthma; an overactive thyroid; seizures; a blockage of the stomach, bowel, or bladder; trouble breathing when you sleep; trouble sleeping; lung problems (eg, emphysema); the blood disease porphyria; or an enlarged prostate or other prostate problems; adrenal gland problems; blood vessel problems; or if you have difficulty urinating

Some MEDICINES MAY INTERACT with Dytan-D Suspension. Tell your health care provider if you are taking any other medicines, especially if any of the following apply to you:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), indomethacin, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects such as severe headache, high blood pressure, or high fever may occur
• Bromocriptine or sodium oxybate (GHB) because the risk of side effects or toxic effects may be increased by Dytan-D Suspension
• Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Dytan-D Suspension.
• Digoxin or droxidopa because side effects such as irregular heartbeat or heart attack may occur
• Urinary alkalinizers (eg, sodium bicarbonate) because the side effects of Dytan-D Suspension may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dytan-D Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dytan-D Suspension:

Use Dytan-D Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Dytan-D Suspension may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Shake well before using.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Dytan-D Suspension and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dytan-D Suspension.

Important safety information:

• Dytan-D Suspension may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Dytan-D Suspension. Using Dytan-D Suspension alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Dytan-D Suspension. Dytan-D Suspension will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• Contact your health care provider if symptoms last for more than 7 days or are accompanied by a fever.
• Diabetes patients – Dytan-D Suspension may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
• Dytan-D Suspension contains phenylephrine and diphenhydramine. Before you begin taking any new prescription or nonprescription medicine, including medicine used on the skin, read the ingredients to see if it also contains phenylephrine or diphenhydramine. If it does, or if you are uncertain if it does, contact your doctor or pharmacist.
• If you are scheduled for allergy skin testing, do not take Dytan-D Suspension for several days before the test because it may decrease your response to the skin tests.
• Do not take diet or appetite control medicines while you are taking Dytan-D Suspension without checking with your doctor.
• Do not exceed the recommended dose or take Dytan-D Suspension for longer than prescribed without checking with your doctor.
• If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Dytan-D Suspension.
• Use Dytan-D Suspension with caution in the ELDERLY because they may be more sensitive to its effects.
• Dytan-D Suspension is not recommended for use in NEWBORNS. Safety and effectiveness have not been confirmed.
• Different products may have different dosing instructions for CHILDREN on the package labeling. Follow the dosing instructions provided on the package labeling or by your doctor. If you are unsure of what dose to give a child, check with your doctor.
• Caution is advised when using Dytan-D Suspension in CHILDREN because they may be more sensitive to its effects, especially excitability.
• PREGNANCY AND BREAST-FEEDING: If you become pregnant while taking Dytan-D Suspension, discuss with your doctor the benefits and risks of using Dytan-D Suspension during pregnancy. If you are or will be breast-feeding while you are using Dytan-D Suspension, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Dytan-D Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability (especially in children); headache; loss of appetite; nausea; nervousness; restlessness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased coordination; difficulty urinating; fast or irregular heartbeat; fever; hallucinations; seizure; severe dizziness and drowsiness; severe nervousness, anxiety, or restlessness; tremors; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include bluish-colored skin; difficulty breathing; dilated pupils; fast or irregular heartbeat; fever; flushing; hallucinations; mental or mood changes; seizures; severe drowsiness or dizziness; severe excitability; severe nausea or vomiting; sweating; tremors.

Proper storage of Dytan-D Suspension:

Store Dytan-D Suspension at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dytan-D Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Dytan-D Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Dytan-D Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dytan-D Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: diphenhydramine (DYE fen HYE dra meen)
Brand Names: Aler-Tab, Allergy, Allermax, Altaryl, Benadryl Allergy, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Children’s Allergy, Diphen Cough, Diphenhist, Dytuss, PediaCare Children’s Allergy, Q-Dryl, Q-Dryl A/F, Siladryl, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep-ettes, Sleep-ettes D, Sominex Maximum Strength Caplet, Theraflu Thin Strips Multi Symptom, Triaminic Thin Strips Cough & Runny Nose, Unisom Sleepgels Maximum Strength, Valu-Dryl

What is Dytuss (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson’s disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dytuss (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Dytuss (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• glaucoma or increased pressure in the eye;

• a stomach ulcer;

• an enlarged prostate, bladder problems or difficulty urinating;

• an overactive thyroid (hyperthyroidism);

• hypertension or any type of heart problems; or

• asthma.

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Dytuss (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Dytuss (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Dytuss (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

• sleepiness, fatigue, or dizziness;

• headache;

• dry mouth; or

• difficulty urinating or an enlarged prostate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dytuss (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

• medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

• any other medications that make you feel drowsy, sleepy, or relaxed.

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 5.01. Revision Date: 04/02/2009 3:16:39 PM.

Generic Name: Diphenhydramine (DYE-fen-HYE-dra-meen)
Brand Name: Examples include Benadryl Allergy and Dytuss

Dytuss Elixir is used for:

Preventing or treating symptoms of hay fever and other upper respiratory allergies or the common cold, such as runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes, and relieving cough. It may also be used for other conditions as determined by your doctor.

Dytuss Elixir is an antihistamine and anticholinergic. It works by blocking the action of histamine, reducing the symptoms of an allergic reaction. It also works in the brain to cause sedation.

Do NOT use Dytuss Elixir if:

• you are allergic to any ingredient in Dytuss Elixir or other similar medicines
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dytuss Elixir:

Some medical conditions may interact with Dytuss Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat
• if you have a history of asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis; lung problems (eg, emphysema); shortness of breath; sleep apnea; heart blood vessel problems; stroke; seizures; a blockage of your stomach, intestine, or bladder; difficulty urinating; diabetes; ulcers; an enlarged prostate or other prostate problems; glaucoma; heart problems; high blood pressure; the blood disease porphyria; phenylketonuria; or an overactive thyroid

Some MEDICINES MAY INTERACT with Dytuss Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dytuss Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dytuss Elixir:

Use Dytuss Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Dytuss Elixir by mouth with or without food.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Use Dytuss Elixir exactly as directed on the package, unless instructed differently by your doctor. If you are taking Dytuss Elixir without a prescription, follow any warnings and precautions on the label.
• If you miss a dose of Dytuss Elixir and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dytuss Elixir.

Important safety information:

• Dytuss Elixir may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Dytuss Elixir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Dytuss Elixir; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Dytuss Elixir may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Dytuss Elixir may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Dytuss Elixir for a few days before the tests.
• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
• Dytuss Elixir may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Dytuss Elixir. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Dytuss Elixir has diphenhydramine in it. Before you start any new medicine, check the label to see if it has diphenhydramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• If your symptoms persist for more than 1 week or if you develop a fever, contact your health care provider.
• Do not use Dytuss Elixir for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
• Use Dytuss Elixir with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
• Different brands of Dytuss Elixir may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dytuss Elixir while you are pregnant. Dytuss Elixir is found in breast milk. If you are or will be breast-feeding while you use Dytuss Elixir, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Dytuss Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; excitability; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; fast heartbeat or pounding in the chest; decreased alertness; hallucinations; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Dytuss Elixir:

Store Dytuss Elixir at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dytuss Elixir out of the reach of children and away from pets.

General information:

• If you have any questions about Dytuss Elixir, please talk with your doctor, pharmacist, or other health care provider.
• Dytuss Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dytuss Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: onabotulinumtoxinA (Botox) (ON a BOT ue LYE num TOX in A)
Brand Names: Botox, Botox Cosmetic

What is onabotulinumtoxinA (Botox)?

OnabotulinumtoxinA (Botox), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

Botox is used to treat cervical dystonia (severe spasms in the neck muscles), muscle spasms in the arms and hands, and severe underarm sweating (hyperhidrosis).

Botox is also used to treat certain eye muscle conditions caused by nerve disorders. This includes uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction.

Botox Cosmetic is used to temporarily lessen the appearance of facial wrinkles.

Botox may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Botox?

The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.

Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur up to several weeks after a botulinum toxin injection. Botulinum toxin injections should be given only by a trained medical professional, even when used for cosmetic purposes. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using this medication more often than prescribed will not make it more effective and may result in serious side effects.

You should not receive this medication if you are allergic to botulinum toxin, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected.

Before receiving a botulinum toxin injection, tell your doctor if you have ALS ( Lou Gehrig’s disease), myasthenia gravis, Lambert-Eaton syndrome, a breathing disorder, trouble swallowing, facial muscle weakness, a change in the appearance of your face, seizures, bleeding problems, heart disease, if you have had or will have surgery, or if you have ever received other botulinum toxin injections such as Dysport or Myobloc.

The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

What should I discuss with my healthcare provider before I receive Botox?

You should not receive this medication if you are allergic to botulinum toxin, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Tell your doctor if you have ever had a side effect after receiving a botulinum toxin in the past

If you have any of these other conditions, you may need a dose adjustment or special tests:

• amyotrophic lateral sclerosis (ALS, or “Lou Gehrig’s disease”);

• myasthenia gravis;

• Lambert-Eaton syndrome;

• a breathing disorder such as asthma or emphysema;

• problems with swallowing;

• facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows);

• a change in the normal appearance of your face;

• a seizure disorder;

• bleeding problems;

• heart disease;

• if you have had or will have surgery (especially on your face); or

• if you have ever received other botulinum toxin injections such as Dysport or Myobloc (especially in the last 4 months).

Botox is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

FDA pregnancy category C. It is not known whether botulinum toxin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.. It is not known whether botulinum toxin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is Botox given?

This medication is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Botox injections should be spaced at least 3 months apart.

Botulinum toxin injections should be given only by a trained medical professional, even when used for cosmetic purposes.

Your injection may be given into more than one area at a time, depending on the condition being treated.

While receiving botulinum toxin injections for an eye muscle conditions, you may need to use eye drops, ointment, a special contact lens or other device to protect the surface of your eye. Follow your doctor’s instructions.

If you are being treated for excessive sweating, shave your underarms about 24 hours before you will receive your injection. Do not apply underarm antiperspirants or deodorants for 24 hours before you receive the injection. Avoid exercise and hot foods or beverages within 30 minutes before the injection.

It may take up to 2 weeks after injection before neck muscle spasm symptoms begin to improve. You may notice the greatest improvement at 6 weeks after injection.

It may take only 1 to 3 days after injection before eye muscle spasm symptoms begin to improve. You may notice the greatest improvement at 2 to 6 weeks after injection.

The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using this medication more often than prescribed will not make it more effective and may result in serious side effects.

What happens if I miss a dose?

Since botulinum toxin has a temporary effect and is given at widely spaced intervals, missing a dose is not likely to be harmful.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, and weak or shallow breathing.

What should I avoid after receiving Botox?

Botox may impair your vision or depth perception. Be careful if you drive or do anything that requires you to be able to see clearly.

Avoid using underarm antiperspirants or deodorants for 24 hours after a botulinum toxin injection if you are being treated for excessive underarm sweating.

Avoid going back to your normal physical activities too quickly after receiving an injection.

Botox side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

The botulinum toxin contained in Botox can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.

Call your doctor at once if you have any of these serious side effects, some of which can occur up to several weeks after an injection:

• trouble breathing, talking, or swallowing;

• hoarse voice, drooping eyelids;

• unusual or severe muscle weakness (especially in a body area that was not injected with the medication);

• loss of bladder control;

• problems with vision;

• crusting or drainage from your eyes;

• severe skin rash or itching;

• fast, slow, or uneven heartbeats; or

• chest pain or heavy feeling, pain spreading to the arm or shoulder, general ill feeling.

Less serious side effects may include:

• muscle weakness near where the medicine was injected;

• bruising, bleeding, pain, redness, or swelling where the injection was given;

• headache, muscle stiffness, neck or back pain;

• fever, cough, sore throat, runny nose, flu symptoms,

• dizziness, drowsiness, tired feeling;

• nausea, diarrhea, stomach pain, loss of appetite;

• dry mouth, dry eyes, ringing in your ears;

• increased sweating in areas other than the underarms;

• itchy or watery eyes, increased sensitivity to light; or

• eyelid swelling or bruising.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Botox?

Other medications such as cold or allergy medicine, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medicines, and irritable bowel medicines can increase some of the side effects of Botox. Tell your doctor if you regularly use any of these medications.

Tell your doctor about all other medications you use, especially:

• an injected antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).

This list is not complete and there may be other drugs that can interact with Botox. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about Botox (onabotulinumtoxinA).

• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 4.02. Revision Date: 03/17/2010 3:56:50 PM.

Generic Name: Diphenhydramine (dye-fen-HYE-dra-meen)
Brand Name: Ben-Tann and Dytan

Dytan Suspension is used for:

Preventing or treating symptoms of hay fever and other upper respiratory allergies or the common cold, such as runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes, and relieving cough. It may also be used for other conditions as determined by your doctor.

Dytan Suspension is an antihistamine and anticholinergic. It works by blocking the action of histamine, reducing the symptoms of an allergic reaction. It also works in the brain to cause sedation.

Do NOT use Dytan Suspension if:

• you are allergic to any ingredient in Dytan Suspension or other similar medicines
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Dytan Suspension:

Some medical conditions may interact with Dytan Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat
• if you have a history of asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis; lung problems (eg, emphysema); shortness of breath; sleep apnea; heart blood vessel problems; stroke; seizures; a blockage of your stomach, intestine, or bladder; difficulty urinating; diabetes; ulcers; an enlarged prostate or other prostate problems; glaucoma; heart problems; high blood pressure; porphyria; phenylketonuria; or an overactive thyroid

Some MEDICINES MAY INTERACT with Dytan Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur
• Monoamine oxidase (MAO) inhibitors (eg, phenelzine) because they may increase the risk of Dytan Suspension’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dytan Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Dytan Suspension:

Use Dytan Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Dytan Suspension by mouth with or without food.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Use Dytan Suspension exactly as directed on the package, unless instructed differently by your doctor. If you are taking Dytan Suspension without a prescription, follow any warnings and precautions on the label.
• If you miss a dose of Dytan Suspension and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dytan Suspension.

Important safety information:

• Dytan Suspension may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Dytan Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Dytan Suspension; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Dytan Suspension may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Dytan Suspension may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Dytan Suspension for a few days before the tests.
• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
• Dytan Suspension may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Dytan Suspension. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Dytan Suspension has diphenhydramine in it. Before you start any new medicine, check the label to see if it has diphenhydramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Do not use Dytan Suspension for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
• If your symptoms persist for more than 1 week or if you develop a fever, contact your health care provider.
• Use Dytan Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
• Different brands of Dytan Suspension may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dytan Suspension while you are pregnant. Dytan Suspension is found in breast milk. If you are or will be breast-feeding while you use Dytan Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Dytan Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; itching; dry mouth, throat, and nose; excitability; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; fast heartbeat or pounding in the chest; decreased alertness; hallucinations; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Dytan Suspension:

Store Dytan Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dytan Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Dytan Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Dytan Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Dytan Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.