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Dura-Gest

30/06/10

Generic Name: guaifenesin/phenylephrine/phenylpropanolamine (gwye FEN e sin/fen ill EFF rin/fen ill proe pa NOLE a meen)
Brand Names: Ami-Tex, Banex, Dura-Gest, Duratex, Enomine, Entex, Fentex, Guaifenex, Phenylfenesin, Quintex

What is Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Guaifenesin is an expectorant. It is used to break up congestion and mucous to ease breathing. Guaifenesin thins mucous, increases lubrication of the respiratory tract (lungs, nose, and throat), and increases the removal of mucous.

Phenylpropanolamine and phenylephrine are decongestants. They constrict (shrink) blood vessels (veins and arteries), which reduces the swelling of mucous membranes in areas such as the nose and sinuses.

Guaifenesin/phenylephrine/phenylpropanolamine is used to treat the symptoms of the common cold and of infections of your sinuses, your lungs, and your throat.

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Guaifenesin/phenylephrine/phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Drink plenty of extra fluids while taking this medication. Do not crush or chew the tablets. Swallow them whole or break them in half where they are scored to make them easier to swallow if needed.

Who should not take Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Do not take guaifenesin/phenylephrine/phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

high blood pressure or any other type of heart disease,
diabetes,
a peripheral vascular disorder (poor circulation),
glaucoma or increased pressure in the eyes,
an overactive thyroid, or
difficulty urinating or an enlarged prostate.

You may not be able to take guaifenesin/phenylephrine/phenylpropanolamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Guaifenesin/phenylephrine/phenylpropanolamine is in the FDA pregnancy category C. This means that it is not known whether guaifenesin/phenylephrine/phenylpropanolamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Guaifenesin/phenylephrine/phenylpropanolamine passes into breast milk and may harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from guaifenesin/phenylephrine/phenylpropanolamine. You may require a lower dose of this medication. Guaifenesin/phenylephrine/phenylpropanolamine has not been approved for use by children younger than 6 years of age.

How should I take Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Take guaifenesin/phenylephrine/phenylpropanolamine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take guaifenesin/phenylephrine/phenylpropanolamine with food if stomach upset occurs. Do not crush or chew the tablets. Swallow them whole or break them in half where they are scored to make them easier to swallow if needed.

To ensure that you get a correct dose, measure the liquid form of guaifenesin/phenylephrine/phenylpropanolamine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Store guaifenesin/phenylephrine/phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a guaifenesin/phenylephrine/phenylpropanolamine overdose include vomiting, high blood pressure (headache, red face, blurred vision), an irregular heartbeat, and numbness of the fingers or toes.

What should I avoid while taking Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Guaifenesin/phenylephrine/phenylpropanolamine may cause dizziness. If you experience dizziness, avoid these activities.

Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine) side effects

No serious side effects from guaifenesin/phenylephrine/phenylpropanolamine are expected. Stop taking guaifenesin/phenylephrine/phenylpropanolamine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take guaifenesin/phenylephrine/phenylpropanolamine and talk to your doctor if you experience

dizziness or headache;
nervousness, restlessness, or insomnia;
nausea or stomach upset; or
difficulty urinating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Heart medications such as methyldopa (Aldomet), reserpine (Serpalan, Serpasil), and guanethidine (Ismelin) may have decreased effects. Talk to your doctor before taking guaifenesin/phenylephrine/phenylpropanolamine.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking guaifenesin/phenylephrine/phenylpropanolamine without first talking to your doctor or pharmacist. Other medications may also contain guaifenesin, phenylephrine, phenylpropanolamine, or other similar drugs. You may accidentally take too much of these medicines.

Drugs other than those listed here may also interact with guaifenesin/phenylephrine/phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about guaifenesin/phenylephrine/phenylpropanolamine written for health professionals that you may read.

What does my medication look like?

Guaifenesin/phenylephrine/phenylpropanolamine is available with a prescription under the brand names Entex and Dura-Gest. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Entex, 200 mg of guaifenesin, 5 mg of phenylephrine, and 45 mg of phenylpropanolamine–orange/white capsules
Entex Liquid, 100 mg of guaifenesin, 5 mg of phenylephrine, and 20 mg of phenylpropanolamine with 5% alcohol per 5 mL (1 teaspoon)– orange-colored liquid
Dura-Gest, 200 mg of guaifenesin, 5 mg of phenylephrine, and 45 mg of phenylpropanolamine–gray/white capsules

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,D

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Dura-Tap/PD

30/06/10

Generic Name: chlorpheniramine and pseudoephedrine (klor fen EER a meen and soo doe e FED rin)
Brand Names: Allerest Maximum Strength, Dayquil Allergy, Deconamine, Dura-Tap/PD, Genaphed Plus, Histex, Sudafed Plus, Sudal-12 Chewable, Tavist-DA, Triaminic Cold and Allergy

What is Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of chlorpheniramine and pseudoephedrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Chlorpheniramine and pseudoephedrine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Always ask a doctor before giving a cold or allergy medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Chlorpheniramine and pseudoephedrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, or pseudoephedrine, or if you have:

kidney disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
an enlarged prostate; or
problems with urination.

If you have any of these conditions, you may not be able to use chlorpheniramine and pseudoephedrine, or you may need a dosage adjustment or special tests during treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine and pseudoephedrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

The chewable tablet should be chewed before you swallow it.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an overdose may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid using other medicines that make you sleepy (such as sleeping pills, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine and pseudoephedrine.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine or decongestant.

Dura-Tap/PD (chlorpheniramine and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
confusion, hallucinations, unusual thoughts or behavior;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
urinating less than usual or not at all.

Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

blurred vision;
dry mouth;
nausea, stomach pain, constipation;
mild loss of appetite, stomach upset;
warmth, tingling, or redness under your skin;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness;
problems with memory or concentration; or
ringing in your ears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

medicines to treat high blood pressure;
a diuretic (water pill);
medication to treat irritable bowel syndrome;
bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or
antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.

If you are using any of these drugs, you may not be able to use chlorpheniramine and pseudoephedrine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect chlorpheniramine and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about chlorpheniramine and pseudoephedrine written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,D

Comments (0)

Durabac

30/06/10

Generic Name: Acetaminophen/Salicylamide/Phenyltoloxamine/Caffeine (a-seet-a-MIN-oh-fen/SAL-i-SIL-a-mide/FEN-il-tole-OX-a-meen/KAF-een)
Brand Name: Examples include Cafgesic and Durabac

Durabac is used for:

Treating minor aches and pains (eg, headache, muscle or joint soreness, minor toothache, menstrual cramps). It is also used to treat symptoms associated with certain conditions (eg, colds, arthritis, muscle spasm, sinusitis). It may also be used for other conditions as determined by your doctor.

Durabac is an analgesic, antihistamine, and antipyretic combination. It works by blocking substances in the body that cause fever, pain, and inflammation. It also blocks histamine, which causes sneezing and itchy, watery eyes.

Do NOT use Durabac if:

you are allergic to any ingredient in Durabac
you have had a severe allergic reaction to aspirin or other salicylates (eg, rash, hives, itching, difficulty breathing, tightness in the chest)
you have kidney or liver problems
you are a child or teenager and have a viral infection (eg, chickenpox, flu, cold)
you are taking sodium oxybate (GHB) or an anticoagulant (eg, warfarin)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Durabac:

Some medical conditions may interact with Durabac. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a viral infection (eg, chickenpox, flu); Kawasaki syndrome; ulcers; a blockage of your stomach, bowel, or bladder; blood or bleeding problems; blood clotting problems; heart problems; blood vessel problems; or high blood pressure.
if you have a history of lung or breathing problems (eg, asthma, emphysema, chronic obstructive pulmonary disease [COPD]), increased pressure in the eye, glaucoma, difficulty urinating, prostate problems (eg, enlarged prostate), anxiety, trouble sleeping, or high blood sugar
if you drink alcohol, have a history of alcohol abuse or dependence, or take a monoamine oxidase inhibitor (MAOI) (eg, phenelzine)

Some MEDICINES MAY INTERACT with Durabac. Tell your health care provider if you are taking any other medicines, especially any of the following:

Sodium oxybate (GHB) because serious side effects such as prolonged sedation and severe drowsiness may occur
Anticoagulants (eg, warfarin) because the risk of side effects, including the risk of bruising or bleeding, may be increased
Aspirin, isoniazid, MAOIs (eg, phenelzine), or quinolones (eg, ciprofloxacin) because they may increase the risk of Durabac’s side effects
Theophylline because the risk of its side effects may be increased by Durabac
Barbiturates (eg, phenobarbital) because their effectiveness may be decreased by Durabac

This may not be a complete list of all interactions that may occur. Ask your health care provider if Durabac may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Durabac:

Use Durabac as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Durabac by mouth with or without food.
If you miss a dose of Durabac and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Durabac.

Important safety information:

Durabac may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Durabac with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Durabac; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If you are taking Durabac for pain or fever and your symptoms do not improve within 10 days or if they become worse, check with your doctor.
Durabac has acetaminophen, caffeine, an aspirin-like medicine, and an antihistamine in it. Before you start any new medicine, check the label to see if it has any of these ingredients in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Durabac contains caffeine. Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate).
Durabac may harm your liver or cause stomach bleeding. Your risk may be greater if you drink alcohol while you are using Durabac. Talk to your doctor before you take Durabac or other fever reducers if you drink more than 3 drinks with alcohol per day.
Tell your doctor or dentist that you take Durabac before you receive any medical or dental care, emergency care, or surgery.
Do not give Durabac to a child or teenager who has chickenpox, the flu, or another viral infection. Use of Durabac for treating the symptoms of a viral infection may cause a serious illness called Reye syndrome.
Durabac may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Durabac.
Use Durabac with caution in the ELDERLY; they may be more sensitive to its effects, especially liver and kidney problems.
Durabac should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Durabac while you are pregnant. Durabac is found in breast milk. Do not breast-feed while taking Durabac.

Possible side effects of Durabac:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, nose, or throat; heartburn; nausea; thickening of mucus in the nose and throat; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black stools; blurred vision or other vision changes; dark urine; decrease in the amount of urine produced; difficulty urinating; fainting; fast or irregular heartbeat; hearing loss; involuntary trembling; loss of coordination; pale stools; ringing in the ears; seizures; severe or persistent dizziness; severe stomach pain; trouble sleeping; unusual bruising or bleeding; unusual tiredness; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include abnormal thoughts or behavior; confusion; dark urine; excessive sweating; fast or deep breathing; fast or irregular heartbeat; general discomfort; hearing loss; high fever; involuntary trembling; ringing in the ears; seizures; severe or persistent stomach pain; trouble sleeping; vomiting; yellowing of the eyes or skin.

Proper storage of Durabac:

Store Durabac at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Durabac out of the reach of children and away from pets.

General information:

If you have any questions about Durabac, please talk with your doctor, pharmacist, or other health care provider.
Durabac is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Durabac. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

D,Med-facts

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Durabac Forte

30/06/10

Generic Name: Acetaminophen/Caffeine/Magnesium Salicylate/Phenyltoloxamine (ah-seet-ah-MIN-oh-fen/ka-FEEN/mag-NEE-zhum sa-LI-si-late/fen-ill-tole-OX-a-meen)
Brand Name: Durabac Forte

Durabac Forte is used for:

Treating mild to moderate aches and pains associated with headache, muscle and joint soreness, muscle spasms, nerve pain, menstrual cramps, colds and flu, sinusitis, toothache, and minor pain from arthritis. It helps restore mental alertness or wakefulness during periods of fatigue or drowsiness. It may also be used for other conditions as determined by your doctor.

Durabac Forte is an analgesic, antipyretic, salicylate, antihistamine, and stimulant combination. It works by decreasing fever, pain, and inflammation. It also blocks histamine, which causes allergy symptoms (eg, sneezing and itchy, watery eyes).

Do NOT use Durabac Forte if:

you are allergic to any ingredient in Durabac Forte
you are allergic to salicylates (eg, aspirin) or NSAIDs (eg, ibuprofen)
you have kidney or liver problems, bleeding problems (eg, hemophilia, active severe bleeding), low blood platelet levels, or Von Willebrand disease
the patient is a child or teenager who has flu symptoms or chickenpox
you are also taking an anticoagulant (eg, warfarin) or sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Durabac Forte:

Some medical conditions may interact with Durabac Forte. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have breathing problems (eg, asthma), blood clotting problems, stomach or intestinal problems (eg, ulcer, blockage, inflammation), prostate problems, urinary blockage, trouble urinating, increased pressure in the eyes (eg, glaucoma), heart or blood vessel problems, high blood pressure, viral hepatitis, anxiety, trouble sleeping, growths in the nose, low blood vitamin K levels, influenza, or chickenpox
if the patient is a child who has a history of stroke, a bulging blood vessel in the brain (aneurysm), an inflammatory condition (rheumatic disease), or Kawasaki syndrome
if you have taken furazolidone or a monamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Some MEDICINES MAY INTERACT with Durabac Forte. Tell your health care provider if you are taking any other medicines, especially any of the following:

Carbonic anhydrase inhibitors (eg, acetazolamide), insulin, meglitinides (eg, nateglinide), sodium oxybate (GHB), sympathomimetics (eg, albuterol, pseudoephedrine), theophyllines (eg, aminophylline), or valproic acid because the risk of their side effects may be increased by Durabac Forte
Anticoagulants (eg, warfarin) because the risk of bruising or bleeding may be increased
Barbiturates (eg, phenobarbital) because they may decrease Durabac Forte’s effectiveness
Medicines that may harm the liver (eg, acetaminophen, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the liver.
Furazolidone, isoniazid, MAO inhibitors (eg, phenelzine), or quinolone antibiotics (eg, ciprofloxacin) because they may increase the risk of Durabac Forte’s side effects
Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), aspirin, probenecid, or sulfinpyrazone because their effectiveness may be decreased by Durabac Forte

This may not be a complete list of all interactions that may occur. Ask your health care provider if Durabac Forte may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Durabac Forte:

Use Durabac Forte as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Durabac Forte by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
If you miss a dose of Durabac Forte and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Durabac Forte.

Important safety information:

Durabac Forte may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Durabac Forte with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Durabac Forte; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Durabac Forte may harm your liver. Your risk may be greater if you drink alcohol while you are using Durabac Forte. Talk to your doctor before you take Durabac Forte or other fever reducers if you drink more than 3 drinks with alcohol per day.
Durabac Forte has a salicylate in it. Before you start any new medicine, check the label to see if it has a salicylate in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Durabac Forte has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate).
Diabetes patients – Durabac Forte may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
If you are taking Durabac Forte for pain and your symptoms do not improve within 10 days or if they become worse or if redness is present, check with your doctor.
Tell your doctor or dentist that you take Durabac Forte before you receive any medical or dental care, emergency care, or surgery.
Durabac Forte has a salicylate in it, which has been linked to a serious illness called Reye syndrome. Do not give Durabac Forte to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
Durabac Forte may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Durabac Forte.
Use Durabac Forte with caution in the ELDERLY; they may be more sensitive to its effects, especially anemia or liver or kidney problems.
Durabac Forte should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: It is not known if Durabac Forte can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Durabac Forte while you are pregnant. Durabac Forte is found in breast milk. Do not breast-feed while taking Durabac Forte.

Possible side effects of Durabac Forte:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; blurred vision; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; fast heartbeat; headache; heartburn; irritability; loss of appetite; nausea; nervousness; thickening of mucus in the nose and throat; trouble sleeping; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black stools; confusion; dark urine or pale stools; decreased coordination; decreased urination; difficulty swallowing; fainting; fever, chills, persistent sore throat, or other signs of infection; hearing loss; hoarseness; irregular heartbeat; muscle weakness; ringing in the ears; seizures; severe or persistent heartburn; severe, persistent, or recurring fast heartbeat; severe stomach pain; severe vomiting; shortness of breath; tremors; unusual bruising or bleeding; unusual tiredness; vomit that looks like coffee grounds; yellowing of the skin or eyes.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include abnormal behavior; confusion; dark urine; delirium; difficulty hearing; excessive sweating; extreme tiredness; fast or deep breathing; loss of consciousness; ringing in the ears; seizures; severe or persistent dizziness, nausea, or vomiting; stomach pain; yellowing of the skin or eyes.

Proper storage of Durabac Forte:

Store Durabac Forte at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Durabac Forte out of the reach of children and away from pets.

General information:

If you have any questions about Durabac Forte, please talk with your doctor, pharmacist, or other health care provider.
Durabac Forte is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Durabac Forte. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

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Duraclon

30/06/10

Generic Name: clonidine (Epidural route)

KLOE-ni-deen

Epidural routeSolution

The 500 microgram/milliliter strength product should be diluted prior to use in an appropriate solution

Epidural clonidine is not recommended for obstetrical, post-partum, or peri-operative pain management. The risk of hemodynamic instability, especially hypotension and bradycardia, from epidural clonidine may be unacceptable in these patients. However, in a rare obstetrical, post-partum or peri-operative patient, potential benefits may outweigh the possible risks

The 500 mcg/mL strength product should be diluted prior to use in an appropriate solution. Epidural clonidine hydrochloride (HCl) is not recommended for obstetrical, post-partum, or peri-operative pain management. The risk of hemodynamic instability, especially hypotension and bradycardia, from epidural clonidine HCl may be unacceptable in these patients. However, in a rare obstetrical, post-partum or peri-operative patient, potential benefits may outweigh the possible risks .

Commonly used brand name(s):

In the U.S.

Duraclon

Available Dosage Forms:

Solution
Injectable

Therapeutic Class: Analgesic

Pharmacologic Class: Alpha-2 Adrenergic Agonist

Uses For Duraclon

Clonidine injection is used with injected pain medicine to treat pain in cancer patients.

Clonidine is to be started under the immediate supervision of your doctor. After your doctor has seen how you respond to clonidine, you may be able to receive this medicine at home.

This medicine is available only with your doctor’s prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, clonidine is used in certain patients with the following medical conditions:

Post-operative shivering (to prevent or treat shivering that occurs after an operation or anesthesia)

Before Using Duraclon

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of clonidine in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. This medicine is usually used in children only when the pain is severe and other pain medicines did not help.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of clonidine in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with Medicines

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acebutolol
Amitriptyline
Amoxapine
Atenolol
Betaxolol
Bevantolol
Bisoprolol
Carteolol
Carvedilol
Celiprolol
Clomipramine
Desipramine
Dilevalol
Dothiepin
Doxepin
Imipramine
Labetalol
Levobunolol
Lofepramine
Metipranolol
Metoprolol
Mirtazapine
Nadolol
Nebivolol
Nortriptyline
Oxprenolol
Penbutolol
Pindolol
Propranolol
Protriptyline
Sotalol
Tertatolol
Timolol
Trimipramine
Verapamil

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Cyclosporine
Fluphenazine
Mepivacaine
Naloxone
Yohimbine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of Duraclon

Clonidine is given continuously as an epidural infusion (run around the spinal cord) using an infusion pump. The pump and its tube should be checked regularly to make sure the clonidine flow has not stopped accidentally. The injection or catheter site should also be checked regularly for signs of infection.

If you are using this medicine at home, make sure you understand exactly how to use it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For injection dosage form:
- For pain:
  - Adults—30 mcg per hour given as a continuous infusion.
  - Children—Dosage is based on body weight and must be determined by your doctor.

Missed Dose

Call your doctor or pharmacist for instructions.

Tell your doctor immediately if you think the clonidine has stopped for any reason.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Duraclon

This medicine should not be stopped without the doctor’s supervision. Serious side effects may occur if clonidine is stopped suddenly.

This medicine may add to the effects of alcohol and other CNS depressants (medicine that may make you drowsy or less alert). Check with your doctor before taking any such depressants while you are using this medicine.

Dizziness, light-headedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help.

This medicine may cause some people to become drowsy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert.

Duraclon Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Dizziness, light-headedness, or fainting
slow heartbeat

Less common

Chest pain
extremely shallow or slow breathing
fast heartbeat
fever
hallucinations (seeing, feeling, or hearing things that are not there)
mental depression
sleepiness (excessive)
vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Anxiety
confusion
dry mouth
nausea
sleepiness

Less common

Constipation
ringing, buzzing, or other unexplained noises in the ears
sweating, unusual
weakness

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Agitation
headache
nervousness
pounding heartbeat
shaking or trembling

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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Duoplant

30/06/10

Generic Name: salicylic acid (Topical route)

sal-i-SIL-ik AS-id

Commonly used brand name(s):

In the U.S.

Akurza
Aliclen
Avosil
Betasal
Compound W
Corn Removing
Dermarest Psoriasis
DHS Sal
Drytex
Duofilm
Duoplant
Freezone
Fung-O
Gets-It Corn/Callus Remover
Gordofilm
Hydrisalic
Ionil
Ionil Plus
Keralyt
Keralyt Scalp
Lupicare
Mediplast
Mg217 Sal-Acid
Mosco Corn & Callus Remover
Neutrogena
Occlusal-HP
Off-Ezy
Oxy Balance
P & S
Palmer’s Skin Success Acne Cleanser
Propa pH
Salac
Sal-Acid Plaster
Salactic Film
Salex
Salitop
Salkera
Sal-Plant Gel
Salvax
Seba-Clear
Stri-Dex
Thera-Sal
Therasoft Anti-Acne
Tinamed
Ti-Seb
Wart-Off Maximum Strength
Zapzyt

In Canada

Acnex
Acnomel Acne Mask
Clear Away Wart Removal System
Compound W One-Step Wart Remover
Compound W Plus
Dr. Scholl’s Clear Away One Step Plantar Wart Remover
Dr. Scholl’s Cushlin Ultra Slim Callus Removers
Dr. Scholl’s Cushlin Ultra Slim Corn Removers
Duoforte 27
Freezone – One Step Callus Remover Pad
Freezone – One Step Corn Remover Pad

Available Dosage Forms:

Soap
Lotion
Liquid
Ointment
Foam
Gel/Jelly
Cream
Pad
Shampoo
Solution
Dressing
Stick

Therapeutic Class: Antiacne

Pharmacologic Class: NSAID

Chemical Class: Salicylate, Non-Aspirin

Uses For Duoplant

Salicylic acid is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Some of these preparations are available only with your doctor’s prescription.

Before Using Duoplant

Allergies

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Also, young children may be more likely to get skin irritation from salicylic acid. Salicylic acid should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Salicylic acid should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with this medicine.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Acenocoumarol
Anisindione
Ardeparin
Certoparin
Dalteparin
Danaparoid
Dicumarol
Enoxaparin
Nadroparin
Parnaparin
Phenindione
Phenprocoumon
Probenecid
Reviparin
Tamarind
Tinzaparin
Warfarin

Interactions with Food/Tobacco/Alcohol

Proper Use of salicylic acid

This section provides information on the proper use of a number of products that contain salicylic acid. It may not be specific to Duoplant. Please read with care.

It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of absorption through the skin and the chance of salicylic acid poisoning.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap) to be applied over this medicine, make sure you know how to apply it. Since an occlusive dressing will increase the amount of medicine absorbed through your skin and the possibility of salicylic acid poisoning, use it only as directed. If you have any questions about this, check with your doctor.

Keep this medicine away from the eyes and other mucous membranes, such as the mouth and inside of the nose. If you should accidentally get some in your eyes or on other mucous membranes, immediately flush them with water for 15 minutes.

To use the cream, lotion, or ointment form of salicylic acid:

Apply enough medicine to cover the affected area, and rub in gently.

To use the gel form of salicylic acid:

Before using salicylic acid gel, apply wet packs to the affected areas for at least 5 minutes. If you have any questions about this, check with your health care professional.
Apply enough gel to cover the affected areas, and rub in gently.

To use the pad form of salicylic acid:

Wipe the pad over the affected areas.
Do not rinse off medicine after treatment.

To use the plaster form of salicylic acid for warts, corns, or calluses:

This medicine comes with patient instructions. Read them carefully before using.
Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
Cut the plaster to fit the wart, corn, or callus and apply.
For corns and calluses:
- Repeat every 48 hours as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
- Corns or calluses may be soaked in warm water for 5 minutes to help in their removal.
For warts:
- Depending on the product, either:
  - Apply plaster and repeat every 48 hours as needed, or
    - Apply plaster at bedtime, leave in place for at least 8 hours, remove plaster in the morning, and repeat every 24 hours as needed.
- Repeat for up to 12 weeks as needed, or as directed by your doctor, until wart is removed.
If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

To use the shampoo form of salicylic acid:

Before applying this medicine, wet the hair and scalp with lukewarm water. Apply enough medicine to work up a lather and rub well into the scalp for 2 or 3 minutes, then rinse. Apply the medicine again and rinse thoroughly.

To use the soap form of salicylic acid:

Work up a lather with the soap, using hot water, and scrub the entire affected area with a washcloth or facial sponge or mitt.
If you are to use this soap in a foot bath, work up rich suds in hot water and soak the feet for 10 to 15 minutes. Then pat dry without rinsing.

To use the topical solution form of salicylic acid for acne:

Wet a cotton ball or pad with the topical solution and wipe the affected areas.
Do not rinse off medicine after treatment.

To use the topical solution form of salicylic acid for warts, corns, or calluses:

This medicine comes with patient instructions. Read them carefully before using.
This medicine is flammable. Do not use it near heat or open flame or while smoking.
Do not use this medicine on irritated skin or on any area that is infected or reddened. Also, do not use this medicine if you are a diabetic or if you have poor blood circulation.
Do not use this medicine on warts with hair growing from them or on warts on the face, in or on the genital (sex) organs, or inside the nose or mouth. Also do not use on moles or birthmarks. To do so may cause severe irritation.
Avoid breathing in the vapors from the medicine.
Wash the area to be treated and dry thoroughly. Warts may be soaked in warm water for 5 minutes before drying.
Apply the medicine one drop at a time to completely cover each wart, corn, or callus. Let dry.
For warts—Repeat one or two times a day as needed for up to 12 weeks, or as directed by your doctor, until wart is removed.
For corns and calluses—Repeat one or two times a day as needed for up to 14 days, or as directed by your doctor, until the corn or callus is removed.
Corns and calluses may be soaked in warm water for 5 minutes to help in their removal.
If discomfort gets worse during treatment or continues after treatment, or if the wart spreads, check with your doctor.

Unless your hands are being treated, wash them immediately after applying this medicine to remove any medicine that may be on them.

Dosing

For cream dosage form:
- For corns and calluses:
  - Adults and children—Use the 2 to 10% cream as needed. Use the 25 to 60% cream one time every three to five days.
For gel dosage form:
- For acne:
  - Adults and children—Use the 0.5 to 5% gel one time a day.
- For psoriasis:
  - Adults and children—Use the 5% gel one time a day.
- For common warts:
  - Adults and children—Use the 5 to 26% gel one time a day.
For lotion dosage form:
- For acne:
  - Adults and children—Use the 1 to 2% lotion one to three times a day.
- For dandruff and antiseborrhic dermatitis of the scalp:
  - Adults and children—Use the 1.8 to 2% lotion on the scalp one or two times a day.
For ointment dosage form:
- For acne:
  - Adults and children—Use the 3 to 6% ointment as needed.
- For psoriasis and seborrheic dermatitis:
  - Adults and children—Use the 3 to 10% ointment as needed.
- For common warts:
  - Adults and children—Use the 3 to 10% ointment as needed. Use the 25 to 60% ointment one time every three to five days.
For pads dosage form:
- For acne:
  - Adults and children—Use one to three times a day.
For plaster dosage form:
- For corns, calluses, common warts, or plantar warts:
  - Adults and children—Use one time a day or one time every other day.
For shampoo dosage form:
- For dandruff or seborrheic dermatitis of the scalp:
  - Adults and children—Use on the scalp one or two times a week.
For soap dosage form:
- For acne:
  - Adults and children—Use as needed.
For topical solution dosage form:
- For acne:
  - Adults and children—Use the 0.5 to 2% topical solution one to three times a day.
- For common warts and plantar warts:
  - Adults and children—Use the 5 to 27% topical solution one or two times a day.
- For corns and calluses:
  - Adults and children—Use the 12 to 27% topical solution one or two times a day.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Duoplant

When using salicylic acid, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:

Abrasive soaps or cleansers
Alcohol-containing preparations
Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, sulfur, or tretinoin [vitamin A acid])
Cosmetics or soaps that dry the skin
Medicated cosmetics
Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid may cause severe irritation of the skin.

Check with your doctor right away if you have nausea, vomiting, dizziness, loss of hearing, tinnitus, lethargy hyperpnea, diarrhea, and psychic disturbances. These could be symptoms of a serious condition called salicylate toxicity, especially in children under 12 years of age and patients with kidney or liver problems.

Duoplant Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Skin irritation not present before use of this medicine (moderate or severe)

Frequency not known

Dryness and peeling of skin
flushing
redness of skin
unusually warm skin

Symptoms of salicylic acid poisoning

Confusion
diarrhea
dizziness
fast or deep breathing
headache (severe or continuing)
hearing loss
lightheadedness
nausea
rapid breathing
ringing or buzzing in ears (continuing)
severe drowsiness
stomach pain
vomiting

More common

Skin irritation not present before use of this medicine (mild)
stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Duoplant Gel

30/06/10

Generic Name: Salicylic Acid (sal-ih-SILL-ik AS-id)
Brand Name: Examples include Duoplant and Sal-Plant

Duoplant Gel is used for:

Removing common warts and warts on the bottom of the foot (plantar warts). It may also be used for other skin conditions as determined by your doctor.

Duoplant Gel is a topical salicylate. It works by causing the skin to swell, soften, and then slough or peel in areas where it is applied.

Do NOT use Duoplant Gel if:

you are allergic to any ingredient in Duoplant Gel
you have diabetes or poor blood circulation

Contact your doctor or health care provider right away if any of these apply to you.

Before using Duoplant Gel:

Some medical conditions may interact with Duoplant Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)
if you have liver or kidney problems, a skin infection, or skin irritation

Some MEDICINES MAY INTERACT with Duoplant Gel. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants, (eg, heparin, warfarin), aspirin, methotrexate, or sulfonylureas (eg, glipizide) because the risk of side effects may be increased by Duoplant Gel

This may not be a complete list of all interactions that may occur. Ask your health care provider if Duoplant Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Duoplant Gel:

Use Duoplant Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

First soak the wart in warm water for about 5 minutes. Dry thoroughly. Apply 1 drop at a time to sufficiently cover each wart. Let dry.
Cover the area with a small adhesive bandage or dressing (if practical) unless your doctor has instructed you not to. Unless your hands are being treated, be sure to wash your hands after each application.
If you miss a dose of Duoplant Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Duoplant Gel.

Important safety information:

Duoplant Gel is for external use only. Avoid getting Duoplant Gel in your eyes, nose, or mouth, or on the genitals. If contact with your eyes occurs, flush with water for 15 minutes. Do not inhale the vapors of Duoplant Gel.
Do not use Duoplant Gel longer or more often than recommended by your doctor or on the package label.
Check with your doctor before use if you have a condition that covers a large area of the body.
Be sure to apply Duoplant Gel only to the affected area and not to normal healthy skin.
Do not use Duoplant Gel on skin that is irritated, infected, or reddened.
Do not use Duoplant Gel on open skin wounds, moles, birthmarks, genital warts, warts on the face, or warts growing hair.
Do not use any other medicines or drying products on your skin unless your doctor instructs you otherwise.
Duoplant Gel may interfere with certain lab test results. Make sure your doctor and lab personnel know you are using Duoplant Gel.
Duoplant Gel is extremely flammable. Do not store or use Duoplant Gel near a fire or other open flame.
Duoplant Gel may be harmful if swallowed. If you may have taken Duoplant Gel by mouth, contact your local poison control center or emergency room immediately.
Duoplant Gel contains a salicylate, which has been linked to Reye syndrome. Do not use Duoplant Gel on children or teenagers during or after chickenpox, flu, or other viral infections without checking with your doctor or pharmacist.
Caution is advised when using Duoplant Gel in CHILDREN because they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Duoplant Gel during pregnancy. It is unknown if Duoplant Gel is excreted in breast milk. If you are or will be breast-feeding while you are using Duoplant Gel, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Duoplant Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry, peeling, red, or scaling skin.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe irritation.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include agitation; diarrhea; dizziness; loss of appetite; loss of hearing; mental disturbances; nausea; rapid or difficult breathing; ringing in the ears; seizures; sluggishness; vomiting; yellowing of the skin or eyes.

Proper storage of Duoplant Gel:

Store Duoplant Gel at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Duoplant Gel out of the reach of children and away from pets.

General information:

If you have any questions about Duoplant Gel, please talk with your doctor, pharmacist, or other health care provider.
Duoplant Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Duoplant Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

D,Med-facts

Comments (0)

Duospore Ointment

30/06/10

Generic Name: Bacitracin/Polymyxin (BAS-i-TRAY-sin/POL-ee-MIX-in)
Brand Name: Examples include Duospore and Polysporin

Duospore Ointment is used for:

Treating or preventing infection in minor skin wounds.

Duospore Ointment is an antibiotic. It works by stopping or preventing bacterial infections by either killing susceptible bacteria or inhibiting their growth.

Do NOT use Duospore Ointment if:

you are allergic to any ingredient in Duospore Ointment

Contact your doctor or health care provider right away if any of these apply to you.

Before using Duospore Ointment:

Some medical conditions may interact with Duospore Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Duospore Ointment. Because little, if any, of Duospore Ointment is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Duospore Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Duospore Ointment:

Use Duospore Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Wash and completely dry the affected area. Gently rub the medicine in until it is evenly distributed. The area may be left uncovered, or you may cover it with a sterile bandage.
Wash your hands immediately after using Duospore Ointment, unless your hands are part of the treated area.
Duospore Ointment works best if used at the same time each day.
To clear up your infection completely, use Duospore Ointment for the full course of treatment. Keep using it even if you feel better in a few days.
If you miss a dose of Duospore Ointment, use it as soon as you remember. Continue to use it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Duospore Ointment.

Important safety information:

Duospore Ointment is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in your eyes, rinse right away with cool water.
Do not use Duospore Ointment to cover large areas of your body. If you have deep puncture wounds, animal bites, or serious burns, check with your doctor.
Do NOT use more than the recommended dose or use for longer than 7 days without checking with your doctor.
PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Duospore Ointment while you are pregnant. It is not known if Duospore Ointment is found in breast milk. If you are or will be breast-feeding while you use Duospore Ointment, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Duospore Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Duospore Ointment. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning; redness; swelling.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Duospore Ointment may be harmful if swallowed.

Proper storage of Duospore Ointment:

Store Duospore Ointment between 59 and 77 degrees F (15 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Duospore Ointment out of the reach of children and away from pets.

General information:

If you have any questions about Duospore Ointment, please talk with your doctor, pharmacist, or other health care provider.
Duospore Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Duospore Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

D,Med-facts

Comments (0)

Duotan Suspension

30/06/10

Generic Name: Chlorpheniramine/Pseudoephedrine (klor-fen-IHR-ah-meen/sue-do-eh-FED-rin)
Brand Name: Examples include Duotan and Durafed

Duotan Suspension is used for:

Relieving symptoms of sinus congestion, sinus pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Duotan Suspension is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant promotes sinus and nasal drainage, relieving congestion and pressure.

Do NOT use Duotan Suspension if:

you are allergic to any ingredient in Duotan Suspension
you have severe high blood pressure, severe heart blood vessel disease, a rapid heartbeat, or severe heart problems
you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Duotan Suspension:

Some medical conditions may interact with Duotan Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat
if you have a history of asthma, lung problems (eg, emphysema), adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or intestines, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate or other prostate problems, seizures, or an overactive thyroid

Some MEDICINES MAY INTERACT with Duotan Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Duotan Suspension’s side effects
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Duotan Suspension
Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Duotan Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Duotan Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Duotan Suspension:

Use Duotan Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Duotan Suspension by mouth with food.
Shake well before each use.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Duotan Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Duotan Suspension.

Important safety information:

Duotan Suspension may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Duotan Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not take diet or appetite control medicines while you are taking Duotan Suspension without checking with you doctor.
Duotan Suspension has pseudoephedrine and chlorpheniramine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine or chlorpheniramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
Duotan Suspension may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Duotan Suspension. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
Duotan Suspension may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Duotan Suspension for a few days before the tests.
Tell your doctor or dentist that you take Duotan Suspension before you receive any medical or dental care, emergency care, or surgery.
Use Duotan Suspension with caution in the ELDERLY; they may be more sensitive to its effects.
Caution is advised when using Duotan Suspension in CHILDREN; they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Duotan Suspension while you are pregnant. It is not known if Duotan Suspension is found in breast milk. Do not breast-feed while taking Duotan Suspension.

Possible side effects of Duotan Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Duotan Suspension:

Store Duotan Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Duotan Suspension out of the reach of children and away from pets.

General information:

If you have any questions about Duotan Suspension, please talk with your doctor, pharmacist, or other health care provider.
Duotan Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Duotan Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

D,Med-facts

Comments (0)

Duotan DM Suspension

30/06/10

Generic Name: Chlorpheniramine/Dextromethorphan/Pseudoephedrine (klor-fen-EER-a-meen/dex-troe-meth-OR-fan/sue-doe-eh-FED-rin)
Brand Name: Examples include Duotan DM and T-Tanna DM

Duotan DM Suspension is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

Duotan DM Suspension is a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing, while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Duotan DM Suspension if:

you are allergic to any ingredient in Duotan DM Suspension
you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
you are unable to urinate or are having an asthma attack
you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Duotan DM Suspension:

Some medical conditions may interact with Duotan DM Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a fast, slow, or irregular heartbeat
if you have a history of adrenal gland problems (eg, adrenal gland tumor); heart problems; high blood pressure; diabetes; blood vessel problems; stroke; glaucoma; a blockage of your stomach, bladder, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid
if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Duotan DM Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because the side effects of Duotan DM Suspension may be increased
Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Duotan DM Suspension
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Duotan DM Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Duotan DM Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Duotan DM Suspension:

Use Duotan DM Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Duotan DM Suspension may be taken with or without food.
Shake well before using.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
If you miss a dose of Duotan DM Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Duotan DM Suspension.

Important safety information:

Duotan DM Suspension may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Duotan DM Suspension. Using Duotan DM Suspension alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
Do not take diet or appetite control medicines while you are taking Duotan DM Suspension without checking with your doctor.
Duotan DM Suspension contains chlorpheniramine, dextromethorphan, and pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains chlorpheniramine, dextromethorphan, or pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
Do NOT exceed the recommended dose or take Duotan DM Suspension for longer than prescribed without checking with your doctor.
If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
Duotan DM Suspension may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Duotan DM Suspension. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
If you are scheduled for allergy skin testing, do not take Duotan DM Suspension for several days before the test because it may decrease your response to the skin tests.
Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Duotan DM Suspension.
Use Duotan DM Suspension with caution in the ELDERLY because they may be more sensitive to its effects.
Caution is advised when using Duotan DM Suspension in CHILDREN because they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Duotan DM Suspension, discuss with your doctor the benefits and risks of using Duotan DM Suspension during pregnancy. It is unknown if Duotan DM Suspension is excreted in breast milk. Do not breast-feed while taking Duotan DM Suspension.

Possible side effects of Duotan DM Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Duotan DM Suspension:

Store Duotan DM Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Duotan DM Suspension out of the reach of children and away from pets.

General information:

If you have any questions about Duotan DM Suspension, please talk with your doctor, pharmacist, or other health care provider.
Duotan DM Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Duotan DM Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

D,Med-facts

Comments (0)

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Drugs & Medications:A-Z

Recent Posts

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30/06/10

What is Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

What is the most important information I should know about Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Who should not take Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

How should I take Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine) side effects

What other drugs will affect Dura-Gest (guaifenesin/phenylephrine/phenylpropanolamine)?

Where can I get more information?

What does my medication look like?

30/06/10

What is Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

What is the most important information I should know about Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

What should I discuss with my healthcare provider before taking Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

How should I take Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Dura-Tap/PD (chlorpheniramine and pseudoephedrine) side effects

What other drugs will affect Dura-Tap/PD (chlorpheniramine and pseudoephedrine)?

Where can I get more information?

30/06/10

Durabac is used for:

Do NOT use Durabac if:

Before using Durabac:

How to use Durabac:

Important safety information:

Possible side effects of Durabac:

If OVERDOSE is suspected:

General information:

30/06/10

Durabac Forte is used for:

Do NOT use Durabac Forte if:

Before using Durabac Forte:

How to use Durabac Forte:

Important safety information:

Possible side effects of Durabac Forte:

If OVERDOSE is suspected:

General information:

30/06/10

Uses For Duraclon

Before Using Duraclon

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of Duraclon

Dosing

Missed Dose

Storage

Precautions While Using Duraclon

Duraclon Side Effects

30/06/10

Uses For Duoplant

Before Using Duoplant

Allergies

Pediatric

Geriatric

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of salicylic acid

Dosing

Missed Dose

Storage

Precautions While Using Duoplant

Duoplant Side Effects

30/06/10

Duoplant Gel is used for:

Do NOT use Duoplant Gel if: