Brand names: Zomig

Why is Zolmitriptan prescribed?

Zomig relieves migraine headaches. It is effective whether or not the headache is preceded by an aura (visual disturbances such as halos and flickering lights). For most people Zomig provides relief within 2 hours, but it will not abort an attack or reduce the number of headaches you experience.

Migraines are thought to be caused by expansion and inflammation of blood vessels in the head. Zomig ends a migraine attack by constricting these blood vessels and reducing inflammation.

Most important fact about Zolmitriptan

Zomig is for use only on common and classic migraine headaches. It should not be used for other types of headache, including certain unusual types of migraine. It has not been tested for cluster headaches, a type of severe headache more common among men.

How should you take Zolmitriptan?

Take Zomig as soon as your first symptoms appear. If the headache comes back after your first dose, you may take a second one 2 hours later. However, if the first dose has no effect at all, do not take a second one unless your doctor advises it, and never take more than 10 milligrams in a day. If taking an orally disintegrating Zomig ZMT tablet, do not remove it from the blister pack until just before use, then immediately place it on your tongue, where it will dissolve in the saliva. Do not break the tablet. Throw away any unused tablets already removed from the blister packaging.

• If you miss a dose…
  Zomig is not for regular use. Take it only when you are having a migraine attack.

• Storage instructions…
  Store Zomig at room temperature, away from heat, light, and moisture. Throw away any remaining tablets after the expiration date printed on the package. Also discard any leftover medicine if your doctor decides to stop treatment with Zomig.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zomig.

• Side effects may include:
  Chest pain or tightness, cold sensation, dizziness, drowsiness, dry mouth, feeling of heaviness in the chest or elsewhere, indigestion, jaw pain or tightness, nausea, neck pain or tightness, pain, skin tingling, sweating, throat pain or tightness, warm sensation, weakness

Why should Zolmitriptan not be prescribed?

You should not take Zomig if you have certain types of heart disease, including angina (chest pain), a history of heart attack, and certain heart irregularities. Also avoid the drug if you have uncontrolled high blood pressure.

Do not use Zomig within 24 hours of taking an ergotamine-based migraine medication or a drug in the same class as Zomig.

Avoid using Zomig within 2 weeks of taking a drug classified as an MAO inhibitor, such as antidepressants.

If Zomig gives you an allergic reaction, do not take it again.

Special warnings about Zolmitriptan

If the first dose of Zomig does not relieve your symptoms, ask your doctor to re-evaluate you; migraine may not be the problem.

Although the danger is very remote, this type of medication has been known to trigger serious and even life-threatening heart problems in people with heart disease. If you have a heart disorder, make sure the doctor knows about it. Do not take Zomig if you suffer from irregular heartbeat.

Very rarely, Zomig has caused serious intestinal problems. See your doctor immediately if you have bloody diarrhea or stomach pain.

If you have risk factors for heart disease, your doctor may ask you to take your first dose of Zomig in the office, and may want to monitor you carefully thereafter. Risk factors that signal the need for caution include high blood pressure, high cholesterol, smoking, excess weight, diabetes, and a strong family history of heart disease or hardening of the arteries. Heart disease is also more likely in postmenopausal women and men over 40.

Use Zomig with caution if you have liver or kidney disease. These conditions could alter the effect of the drug. If you have a history of seizures, make sure the doctor is aware of it. Also, if you develop any trouble with your eyes, alert your doctor. There is a possibility the problem could be related to Zomig.

If you experience pain or tightness in your chest or throat when using Zomig, tell your doctor. If the chest pain is severe or does not go away, seek medical attention immediately. These pains could be symptoms of a previously undetected heart condition.

If you develop shortness of breath, wheezing, a throbbing heartbeat, swelling of the eyelids, face, or lips, or a skin rash, skin lumps, or hives after taking Zomig, call your doctor immediately, and do not take any more of the drug without your doctor’s approval.

If a headache feels different from your usual migraine, check with your doctor before using Zomig.

If you must avoid phenylalanine, do not use the orally disintegrating Zomig ZMT tablets, which contain this substance.

Possible food and drug interactions when taking Zolmitriptan

Remember that Zomig should never be combined with the following drugs (see “Why should Zolmitriptan not be prescribed?”):

Ergotamine-type drugs
MAO inhibitors such as antidepressant drugs
Sumatriptan

If Zomig is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is especially important to check with your doctor before combining Zomig with the following:

Acetaminophen
Cimetidine
Fluoxetine
Fluvoxamine
Oral contraceptives
Paroxetine
Propranolol
Sertraline

Special information if you are pregnant or breastfeeding

The effects of Zomig during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Although researchers have not confirmed it, Zomig may appear in breast milk and could affect a nursing infant. Check with your doctor before using Zomig while breastfeeding.

Recommended dosage for Zolmitriptan

ADULTS

The recommended starting dose is no more than 2.5 milligrams. Higher doses have little additional effect, but tend to cause more side effects. If the headache returns, the dose may be repeated after 2 hours. Do not exceed 10 milligrams in a day.

If you have liver disease, your doctor will prescribe a lower dose and closely monitor your blood pressure.

CHILDREN AND OLDER ADULTS

The safety and effectiveness of Zomig have not been established in children and adults over 65.

Overdosage

The only known symptom of Zomig overdose is drowsiness. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Generic name: Ondansetron hydrochloride
Brand names: Zofran ODT, Zofran

Why is Zofran ODT prescribed?

Zofran is used for the prevention of nausea and vomiting caused by radiation therapy and chemotherapy for cancer, and, in some cases, to prevent these problems following surgery.

Most important fact about Zofran ODT

To ensure the maximum effect, it is important to take all doses of Zofran exactly as prescribed by your doctor.

How should you take Zofran ODT?

Your doctor will tell you how much drug to take and how often, depending on the type of therapy you will be having.

Zofran is available in three forms: an oral solution, tablets that you swallow with water, and orally disintegrating tablets that can be swallowed with saliva alone (Zofran ODT). If you’re taking the orally disintegrating tablets, don’t remove them from the blister pack until it’s time for a dose. Then peel off the foil backing with dry hands, gently remove the tablet, and immediately place it on your tongue. Do not attempt to push the tablets through the foil.

• If you miss a dose…
  Take the forgotten dose as soon as you remember.

• Storage instructions…
  Store Zofran at room temperature. Protect from light. Keep the drug in the carton it came in. Store oral solution bottles upright.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zofran.

• Side effects may include:
  Blurred vision, constipation, diarrhea, dizziness, fatigue, headache

• When Zofran is used to prevent nausea and vomiting after surgery, the following side effects may occur:
  Anxiety, difficulty breathing, difficulty urinating, dizziness, drowsiness, female reproductive disorders, fever, headache, itching, low blood pressure, shivers, slow heartbeat

Why should Zofran ODT not be prescribed?

If you are sensitive to or have ever had an allergic reaction to ondansetron hydrochloride, you should not take Zofran ODT. Make sure that your doctor is aware of any drug reactions that you have experienced.

Special warnings about Zofran ODT

If drugs similar to Zofran have given you a reaction, Zofran may cause one too.

If you suffer from phenylketonuria (an excess of the amino acid phenylalanine) remember that Zofran contains this substance.

Possible food and drug interactions when taking Zofran ODT

No interactions with Zofran have been reported.

Special information if you are pregnant or breastfeeding

The effects of Zofran during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Zofran may appear in breast milk and could affect a nursing infant. If Zofran ODT is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Zofran ODT is finished.

Recommended dosage for Zofran ODT

Dosage is the same for both regular and orally disintegrating tablets. If you have poor liver function, you should take no more than 8 milligrams of Zofran per day.

PREVENTION OF NAUSEA AND VOMITING DUE TO CHEMOTHERAPY

Adults and Children 12 Years of Age and Older

The recommended dose of Zofran is one 8-milligram tablet or 2 teaspoonfuls of oral solution taken twice a day. The first dose should be taken 30 minutes before the start of treatment. The other dose should be taken 8 hours after the first dose. One 8-milligram tablet or 2 teaspoonfuls should be taken twice a day (every 12 hours) for 1 to 2 days after completing chemotherapy.

If the chemotherapy is especially likely to cause nausea and vomiting, the recommended dosage is one 24-milligram tablet taken 30 minutes before the treatment.

Children 4 through 11 Years of Age

The recommended dose of Zofran is one 4-milligram tablet or 1 teaspoonful of oral solution taken 3 times a day. The first dose should be taken 30 minutes before the start of chemotherapy. The other 2 doses should be taken 4 and 8 hours after the first dose. One 4-milligram tablet or 1 teaspoonful should be taken 3 times a day (every 8 hours) for 1 to 2 days after completing chemotherapy.

PREVENTION OF NAUSEA AND VOMITING DUE TO RADIATION THERAPY

Adults

The usual dosage is one 8-milligram tablet or 2 teaspoonfuls of oral solution taken 3 times a day. You will take the first dose 1 to 2 hours before therapy; the other intervals will depend on the type of radiation therapy you are receiving.

Children

Zofran has not been used for this purpose in children.

PREVENTION OF NAUSEA AND VOMITING AFTER SURGERY

Adults

The usual dose is two 8-milligram tablets or 4 teaspoonfuls of oral solution taken 1 hour before undergoing anesthesia.

Children

Zofran has not been used for this purpose in children.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Zofran overdose may include:
  Low blood pressure and fainting, sudden blindness, severe constipation

Generic name: Ondansetron hydrochloride
Brand names: Zofran ODT, Zofran

Why is Zofran prescribed?

Zofran is used for the prevention of nausea and vomiting caused by radiation therapy and chemotherapy for cancer, and, in some cases, to prevent these problems following surgery.

Most important fact about Zofran

To ensure the maximum effect, it is important to take all doses of Zofran exactly as prescribed by your doctor.

How should you take Zofran?

Your doctor will tell you how much drug to take and how often, depending on the type of therapy you will be having.

Zofran is available in three forms: an oral solution, tablets that you swallow with water, and orally disintegrating tablets that can be swallowed with saliva alone (Zofran ODT). If you’re taking the orally disintegrating tablets, don’t remove them from the blister pack until it’s time for a dose. Then peel off the foil backing with dry hands, gently remove the tablet, and immediately place it on your tongue. Do not attempt to push the tablets through the foil.

• If you miss a dose…
  Take the forgotten dose as soon as you remember.

• Storage instructions…
  Store Zofran at room temperature. Protect from light. Keep the drug in the carton it came in. Store oral solution bottles upright.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zofran.

• Side effects may include:
  Blurred vision, constipation, diarrhea, dizziness, fatigue, headache

• When Zofran is used to prevent nausea and vomiting after surgery, the following side effects may occur:
  Anxiety, difficulty breathing, difficulty urinating, dizziness, drowsiness, female reproductive disorders, fever, headache, itching, low blood pressure, shivers, slow heartbeat

Why should Zofran not be prescribed?

If you are sensitive to or have ever had an allergic reaction to ondansetron hydrochloride, you should not take Zofran. Make sure that your doctor is aware of any drug reactions that you have experienced.

Special warnings about Zofran

If drugs similar to Zofran have given you a reaction, Zofran may cause one too.

If you suffer from phenylketonuria (an excess of the amino acid phenylalanine) remember that Zofran contains this substance.

Possible food and drug interactions when taking Zofran

No interactions with Zofran have been reported.

Special information if you are pregnant or breastfeeding

The effects of Zofran during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Zofran may appear in breast milk and could affect a nursing infant. If Zofran is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Zofran is finished.

Recommended dosage for Zofran

Dosage is the same for both regular and orally disintegrating tablets. If you have poor liver function, you should take no more than 8 milligrams of Zofran per day.

PREVENTION OF NAUSEA AND VOMITING DUE TO CHEMOTHERAPY

Adults and Children 12 Years of Age and Older

The recommended dose of Zofran is one 8-milligram tablet or 2 teaspoonfuls of oral solution taken twice a day. The first dose should be taken 30 minutes before the start of treatment. The other dose should be taken 8 hours after the first dose. One 8-milligram tablet or 2 teaspoonfuls should be taken twice a day (every 12 hours) for 1 to 2 days after completing chemotherapy.

If the chemotherapy is especially likely to cause nausea and vomiting, the recommended dosage is one 24-milligram tablet taken 30 minutes before the treatment.

Children 4 through 11 Years of Age

The recommended dose of Zofran is one 4-milligram tablet or 1 teaspoonful of oral solution taken 3 times a day. The first dose should be taken 30 minutes before the start of chemotherapy. The other 2 doses should be taken 4 and 8 hours after the first dose. One 4-milligram tablet or 1 teaspoonful should be taken 3 times a day (every 8 hours) for 1 to 2 days after completing chemotherapy.

PREVENTION OF NAUSEA AND VOMITING DUE TO RADIATION THERAPY

Adults

The usual dosage is one 8-milligram tablet or 2 teaspoonfuls of oral solution taken 3 times a day. You will take the first dose 1 to 2 hours before therapy; the other intervals will depend on the type of radiation therapy you are receiving.

Children

Zofran has not been used for this purpose in children.

PREVENTION OF NAUSEA AND VOMITING AFTER SURGERY

Adults

The usual dose is two 8-milligram tablets or 4 teaspoonfuls of oral solution taken 1 hour before undergoing anesthesia.

Children

Zofran has not been used for this purpose in children.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Zofran overdose may include:
  Low blood pressure and fainting, sudden blindness, severe constipation

Generic name: Simvastatin
Brand names: Zocor

Why is Zocor prescribed?

Zocor is a cholesterol-lowering drug. Your doctor may prescribe Zocor in addition to a cholesterol-lowering diet if your blood cholesterol level is too high, and if you have been unable to lower it by diet alone. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it’s 190.

In people with high cholesterol and heart disease, Zocor reduces the risk of heart attack, stroke, and “mini-stroke” (transient ischemic attack) and can stave off the need for bypass surgery or angioplasty to clear clogged arteries. Zocor can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke.

Most important fact about Zocor

Zocor is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol level under control. It’s important to remember that Zocor is a supplement to—not a substitute for—those other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor. All these efforts to keep your cholesterol levels normal are important because together they may lower your risk of heart disease.

How should you take Zocor?

Take Zocor exactly as prescribed.

• If you miss a dose…
  Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

• Storage instructions…
  Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking Zocor.

• Side effects may include:
  Abdominal pain, headache

Why should Zocor not be prescribed?

Do not take Zocor if you have ever had an allergic reaction to it or are sensitive to it.

Do not take Zocor if you have active liver disease.

Do not take Zocor if you are pregnant or plan to become pregnant.

Special warnings about Zocor

Because Zocor may damage the liver, your doctor may order a blood test to check your liver enzyme levels before you start taking the drug. Blood tests will probably be done before your treatment is started and at periodic intervals for a year after your final dosage increase. If your liver enzyme levels rise too high, your doctor may tell you to stop taking Zocor.

Since Zocor may cause damage to muscle tissue, be sure to tell your doctor of any unexplained muscle tenderness, weakness, or pain right away, especially if you also have a fever or feel sick. Your doctor may want to do a blood test to check for signs of muscle damage.

If you are scheduled for major surgery, your doctor will have you stop taking Zocor a few days before the operation.

Possible food and drug interactions when taking Zocor

Zocor tends to enhance the effects of the blood-thinning drug Coumadin and the heart medication Lanoxin. Combining it with the following drugs increases the chance of muscle damage:

Amiodarone
Clarithromycin
Clofibrate
Cyclosporine
Erythromycin
Fenofibrate
Gemfibrozil
Itraconazole
Ketoconazole
Nefazodone
Nicotinic acid or niacin
Protease inhibitors (used in the treatment of HIV)
Verapamil

If you are taking Zocor with any of these drugs (or with large quantities of grapefruit juice) alert your doctor immediately at the first sign of muscle pain or weakness. If you need to take erythromycin, the doctor may temporarily take you off Zocor.

Special information if you are pregnant or breastfeeding

You must not become pregnant while taking Zocor. This drug lowers cholesterol, and cholesterol is needed for a baby to develop properly. If you do become pregnant while taking Zocor, notify your doctor right away. Based on studies of other cholesterol-lowering drugs, it is assumed that Zocor could appear in breast milk and could cause severe adverse effects in a nursing baby. Do not take Zocor while breastfeeding your baby.

Recommended dosage for Zocor

You will have to follow a standard cholesterol-lowering diet before starting treatment with Zocor and continue this diet while using Zocor.

All doses should be adjusted to your individual needs.

ADULTS

The usual starting dose is 20 to 40 milligrams once a day in the evening. If your cholesterol level or heart attack risk is especially high, the doctor may start with a dose of 40 milligrams. The dosage can be adjusted every 4 weeks. Some people with severe, hereditary high cholesterol may be prescribed as much as 80 milligrams a day, taken in doses of 20, 20, and 40 milligrams, along with other treatments.

Those who have severe kidney disease should use Zocor with caution. The recommended starting dose is 5 milligrams per day.

When combined with cyclosporine, niacin, gemfibrozil, or fenofibrate, the dosage of Zocor should not exceed 10 milligrams a day. When combined with amiodarone, the dosage of Zocor should not exceed 20 milligrams a day.

CHILDREN 10 TO 17 YEARS OLD

The recommended starting dose is 10 milligrams once a day in the evening. The dosage may be increased every 4 weeks, as determined by the doctor, up to a maximum of 40 milligrams a day. Girls must have been menstruating for at least 1 year before starting therapy with Zocor.

The safety and effectiveness of Zocor in children under 10 years old or in doses greater than 40 milligrams a day have not been studied.

Overdosage

Although no specific information about Zocor overdose is available, any medication taken in excess can have serious consequences. If you suspect an overdose of Zocor, seek medical attention immediately.

Generic name: Azithromycin suspension, extended-release
Brand names: Zmax

Why is Zmax prescribed?

Zmax is an antibiotic that kills bacteria. It is used to treat sinus infections and certain kinds of pneumonia (lung infections). Zmax only works against bacteria. It does not work against viruses such as the common cold or flu.

Most important fact about Zmax

Zmax is dosed differently from other antibiotics. The complete course of treatment is just one dose taken one time. If your symptoms have not improved 3 days after taking your dose of Zmax, call your doctor.

How should you take Zmax?

It’s best to take Zmax on an empty stomach (1 hour before or 2 hours after a meal.) Shake the bottle well before using. Take all of the medicine in the bottle.

If you receive Zmax in its liquid form, you may take it as is. If you receive it in powder form, you must prepare it before taking your prescribed dose. Add a quarter cup of water to the Zmax powder and shake thoroughly. Use the solution within 12 hours after the water is added.

• Storage instructions…
  Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zmax.

• Side effects may include:
  Allergic reaction (hives, face/throat swelling, trouble swallowing, wheezing or trouble breathing), diarrhea, headache, nausea/vomiting, stomach pain

Why should Zmax not be prescribed?

Do not take Zmax if you are allergic to azithromycin, erythromycin, ketolide, macrolide antibiotics, or telithromycin. Also, if you are allergic to anything in Zmax, do not take it.

Special warnings about Zmax

Like all antibiotics, Zmax could cause a severe allergic reaction. If you develop signs of an allergic reaction—including hives, swelling of the face or throat, trouble swallowing, or breathing problems—seek emergency medical treatment immediately.

As with all antibiotics, Zmax could cause a severe intestinal problem known as pseudomembranous colitis. Call your doctor right away if you develop diarrhea that does not go away, or diarrhea that is severe, watery, or bloody. Also, contact your doctor if you vomit within the first hour of taking Zmax.

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Zmax. Also, talk to your doctor about your complete medical history, especially if you have kidney or liver problems.

Let your doctor know if you are not feeling any better a few days after taking Zmax.

Possible food and drug interactions when taking Zmax

If Zmax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zmax with the following:

Anti-HIV medication
Anti-seizure medication
Cyclosporine
Digoxin
Ergot derivatives such as ergotamine or dihydroergotamine
Hexobarbital
Migraine medication
Phenytoin
Warfarin

Special information if you are pregnant or breastfeeding

The effects of Zmax during pregnancy are unknown. Tell your doctor immediately if you are pregnant or planning to become pregnant.

You should not take Zmax if you are breastfeeding, since the drug may pass into breast milk.

Recommended dosage for Zmax

ADULTS

Zmax should be taken all at once, in a single dose. This dose delivers 2 grams of azithromycin.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Generic name: Azithromycin
Brand names: Zithromax

Why is Zithromax prescribed?

Zithromax is an antibiotic related to erythromycin. It is prescribed for adults to treat certain mild to moderate skin infections; upper and lower respiratory tract infections, including pharyngitis (strep throat), tonsillitis, sinus infections, worsening of chronic obstructive pulmonary disease, and pneumonia; sexually transmitted infections of the cervix or urinary tract; and genital ulcer disease in men. In children, Zithromax is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat.

Most important fact about Zithromax

There is a possibility of rare but very serious reactions to Zithromax, including angioedema (swelling of the face, lips, and neck that impedes speaking, swallowing, and breathing), anaphylaxis (a violent, even fatal allergic reaction), and serious skin diseases. If you develop these symptoms, stop taking Zithromax and call your doctor immediately.

How should you take Zithromax?

Take Zithromax capsules at least 1 hour before or 2 hours after a meal. Zithromax tablets and oral suspension can be taken with or without food. Do not take any form with an antacid that contains aluminum or magnesium.

If you are using single-dose packets of Zithromax powder for oral suspension, mix the entire contents of each packet with 2 ounces of water, drink immediately, then add an additional 2 ounces of water, mix again, and drink to make sure you’ve taken the entire dose. When giving the pediatric suspension, shake the bottle thoroughly before each use and measure the dose with the supplied calibrated dropper. Use the pediatric suspension within 10 days and throw out any that remains.

Your doctor will only prescribe Zithromax to treat a bacterial infection; it will not cure a viral infection, such as the common cold. It’s important to take the full dosage schedule of Zithromax, even if you’re feeling better in a few days. Not completing the full dosage schedule may decrease the drug’s effectiveness and increase the chances that the bacteria may become resistant to Zithromax and similar antibiotics.

• If you miss a dose…
  Take the forgotten dose as soon as you remember. If you don’t remember until the next day, skip the dose and go back to your regular schedule. Never try to “catch up” by doubling the dose.

• Storage instructions…
  Zithromax should be stored at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zithromax.

• Side effects may include:
  Abdominal pain, diarrhea or loose stools, nausea or vomiting

The single large dose of Zithromax that is prescribed to treat sexually transmitted infection of the cervix or urinary tract is more likely to cause stomach and bowel side effects than the smaller doses prescribed for a skin or respiratory tract infection.

Why should Zithromax not be prescribed?

Do not take Zithromax if you have ever had an allergic reaction to it or to similar antibiotics such as erythromycin.

Special warnings about Zithromax

Like certain other antibiotics, Zithromax may cause a potentially life-threatening form of diarrhea called pseudomembranous colitis. Pseudomembranous colitis may clear up spontaneously when the drug is stopped; if it doesn’t, hospital treatment may be required. If you develop diarrhea, check with your doctor immediately.

If you have a liver problem, your doctor should monitor you very carefully while you are taking Zithromax.

Possible food and drug interactions when taking Zithromax

Do not take Zithromax with antacids containing aluminum or magnesium.

If Zithromax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zithromax with the following:

Cyclosporine
Digoxin
Ergot-containing drugs, including certain migraine medications
Hexobarbital
Nelfinavir
Phenytoin
Warfarin

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. You should take Zithromax during pregnancy only if it is clearly needed. It is not known whether Zithromax can make its way into breast milk. If the drug is essential to your health, your doctor may advise you to stop breastfeeding until your treatment is finished.

Recommended dosage for Zithromax

ADULTS

Pneumonia, Chronic Obstructive Pulmonary Disease, Tonsillitis, Strep Throat, and Skin Infections

The usual dose of Zithromax is 500 milligrams in a single dose the first day. This is followed by 250 milligrams once daily for the next 4 days. Alternatively, patients with chronic obstructive pulmonary disease may be prescribed 500 milligrams a day for 3 days.

Sinus Infection

The usual dose of Zithromax is 500 milligrams once a day for 3 days.

Genital Ulcer Disease

The usual dose is a single gram (1,000 milligrams) one time only.

Sexually Transmitted Diseases

The usual dose is a single 2-gram (2,000 milligrams) dose.

CHILDREN

Middle Ear Infection

For children aged 6 months and up, treatment may be given three ways. One option is a single dose of 30 milligrams per 2.2 pounds of body weight. Another option is a dose of 10 milligrams per 2.2 pounds given each day for 3 days. Zithromax can also be given over a period of 5 days, starting with a dose of 10 milligrams per 2.2 pounds on the first day and continuing with daily doses of 5 milligrams per 2.2 pounds for the next 4 days.

Sinus Infection

For children aged 6 months and up, the usual dose is 10 milligrams of Zithromax suspension per 2.2 pounds of body weight given once daily for 3 days.

Pneumonia

For children aged 6 months and up, the usual dose is 10 milligrams of Zithromax suspension per 2.2 pounds of body weight in a single dose the first day, followed by 5 milligrams per 2.2 pounds for the next 4 days.

Strep Throat and Tonsillitis

For children aged 2 years and up, the usual dose is 12 milligrams per 2.2 pounds of body weight once daily for 5 days.

Overdosage

Although no specific information on Zithromax overdose is available, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Brand names: Geodon

Why is Ziprasidone hydrochloride prescribed?

Geodon is used to treat schizophrenia and the manic episodes of bipolar disorder. Researchers believe it works by opposing the action of serotonin and dopamine, two of the brain’s major chemical messengers. Because of its potentially serious side effects, Geodon is typically prescribed only after other medications have proved inadequate.

Geodon is usually taken in capsule form. An injectable version is available for quick relief of agitated patients. Injectable Geodon is generally used for no more than a few days.

Most important fact about Ziprasidone hydrochloride

In some people with heart problems or a slow heartbeat, Geodon can cause serious and potentially fatal heartbeat irregularities. The chance of a problem is greater if you are taking a water pill (diuretic) or a medication that prolongs a part of the heartbeat known as the QT interval. Many of the drugs prescribed for heartbeat irregularities prolong the QT interval and should never be combined with Geodon. Other drugs to avoid when taking Geodon include chlorpromazine, gatifloxacin, mefloquine, mesoridazine, moxifloxacin, pentamidine, pimozide, soarfloxacin, tacrolimus, and thioridazine. If you’re uncertain about the risks of any drug you’re taking, be sure to check with your doctor before combining it with Geodon.

Geodon is not approved for elderly patients with dementia-related psychosis (such as the type that may occur with Alzheimer’s disease) due to the risk of sudden death, heart failure, pneumonia, and stroke.

How should you take Ziprasidone hydrochloride?

Geodon capsules should be taken twice a day with food.

• If you miss a dose…
  Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

• Storage instructions…
  Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Geodon.

• Side effects may include:
  Accidental injury, anorexia, cold symptoms, constipation, cough, diarrhea, dizziness, drowsiness, dry mouth, energy loss, headache, indigestion, involuntary muscle contractions, muscle aches, muscle tightness, nausea, rapid heartbeat, rash, skin fungus, stuffy and runny nose, twitching, upper respiratory infection, vision problems, vomiting, weakness

Why should Ziprasidone hydrochloride not be prescribed?

Do not take Geodon if you have the heartbeat irregularity known as QT prolongation, have had a recent heart attack, or suffer from heart failure. You’ll also need to avoid Ziprasidone hydrochloride if it gives you an allergic reaction.

Special warnings about Ziprasidone hydrochloride

Remember that Geodon can cause dangerous—even fatal—heartbeat irregularities. Warning signs include dizziness, palpitations, and fainting. Tell your doctor immediately if you experience any of these symptoms. Be careful to avoid drugs that prolong the QT interval of the heartbeat. Check with your doctor before combining any other medication with Geodon.

Particularly during the first few days of therapy, Geodon can cause low blood pressure, with accompanying dizziness, fainting, and rapid heartbeat. Tell your doctor if you experience any of these side effects. To minimize such problems, your doctor will increase your dose gradually. If you are prone to low blood pressure, take blood pressure medicine, become dehydrated, or have heart disease or poor circulation in the brain, use Geodon with caution.

Geodon may cause drowsiness and can impair your judgment, thinking, and motor skills. Use caution while driving and don’t operate potentially dangerous machinery until you know how Ziprasidone hydrochloride affects you.

Geodon poses a very slight risk of seizures, especially if you are over age 65, have a history of seizures, or have Alzheimer’s disease.

Drugs such as Geodon sometimes cause a condition called Neuroleptic Malignant Syndrome (NMS). Symptoms include high fever, muscle rigidity, irregular pulse or blood pressure, rapid heartbeat, excessive perspiration, and changes in heart rhythm. If these symptoms appear, tell your doctor immediately. You’ll need to stop taking Geodon while the condition is under treatment.

There also is the risk of developing tardive dyskinesia, a condition marked by slow, rhythmical, involuntary movements. This problem is more likely to occur in mature adults, especially older women. When it does, use of Geodon is usually stopped.

While taking Geodon, some patients with bipolar disorder reported having anxiety, restlessness, depression, dizziness, muscle twitching, rashes, and vomiting. Contact your doctor immediately if you develop these symptoms.

Geodon can suppress the cough reflex; you may have trouble clearing your airway. Some people taking Geodon also develop a rash. Tell your doctor when this happens. If the rash doesn’t clear up with treatment, you may have to discontinue the drug.

Other antipsychotic medications have been known to interfere with the body’s temperature-regulating mechanism, causing the body to overheat. Although this problem has not occurred with Geodon, caution is still advisable. Avoid exposure to extreme heat, strenuous exercise, and dehydration. There also is a remote chance that Ziprasidone hydrochloride may cause abnormal, prolonged and painful erections.

Animal studies suggest that Geodon may increase the risk of breast cancer, although human studies have not confirmed such a risk. If you have a history of breast cancer, see your doctor regularly for checkups.

Possible food and drug interactions when taking Ziprasidone hydrochloride

Remember that you must never combine Geodon with any drug that prolongs the part of the heartbeat known as the QT interval (see “Most important fact about Ziprasidone hydrochloride”). Check with your doctor or pharmacist if you have any doubts about a drug you’re taking.

If Geodon is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Geodon with the following:

Carbamazepine
Certain blood pressure medications
Drugs that boost the effects of dopamine such as bromocriptine, pramipexole, and ropinirole
Drugs that affect the brain and nervous system, such as sedatives, tranquilizers, and antidepressants
Ketoconazole
Levodopa

Special information if you are pregnant or breastfeeding

Geodon has caused fetal harm when tested in animals. It should be taken during pregnancy only if the benefits outweigh the potential risk. Notify your doctor as soon as you become pregnant or plan to become pregnant.

It is not known whether Geodon appears in breast milk, and breastfeeding is not recommended.

Recommended dosage for Ziprasidone hydrochloride

GEODON

Schizophrenia

The usual starting dose is 20 milligrams twice a day. If needed, the dosage may be increased at several-week intervals up to a maximum of 80 milligrams twice a day.

Acute Manic Episodes Associated with Bipolar Disorder

The usual starting dose is 40 milligrams twice a day with food. On the second day of treatment, the doctor will increase the dose to 60 or 80 milligrams twice a day. For maintenance treatment, the dosage range is usually 40 to 80 milligrams twice a day.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical help immediately.

• Symptoms of Geodon overdose may include:
  Anxiety, drowsiness, tremors, slurred speech, high blood pressure

Generic name: Bisoprolol fumarate, Hydrochlorothiazide
Brand names: Ziac

Why is Ziac prescribed?

Ziac is used to treat high blood pressure. It combines a beta-blocker (bisoprolol) with a thiazide diuretic (hydrochlorothiazide). Beta-blockers decrease the force and rate of heart contractions, thus lowering blood pressure. Diuretics help your body produce and eliminate more urine, which also helps lower blood pressure.

Most important fact about Ziac

Ziac does not cure high blood pressure; it merely keeps it under control. Therefore, you must continue taking it even if you are feeling well. Do not stop taking Ziac unless instructed to do so by your doctor. This is especially important if you have coronary artery disease. Abruptly stopping Ziac could cause chest pain, heart rhythm problems, and even heart attack.

How should you take Ziac?

Take Ziac exactly as prescribed, even if your symptoms have disappeared. Try not to miss any doses. If Ziac is not taken regularly, your condition may worsen.

• If you miss a dose…
  Take the missed dose as soon as possible. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

• Storage instructions…
  Store at room temperature in a tightly closed container.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine whether it is safe for you to continue taking Ziac.

• More common side effects may include:
  Dizziness, fatigue

Additional side effects have been reported with Ziac, although it’s unknown if the drug was the cause. Be sure to tell your doctor about any unusual or severe symptoms.

Why should Ziac not be prescribed?

Do not take Ziac if you have inadequate blood supply to the circulatory system (cardiogenic shock), certain types of irregular heartbeat, a slow heartbeat, bronchial asthma, or severe congestive heart failure. Also avoid the drug if you have trouble urinating.

Do not use Ziac if you have an allergic reaction to the drug.

Special warnings about Ziac

Use Ziac cautiously if you have a history of congestive heart failure.

Do not suddenly stop taking Ziac (see “Most important fact about Ziac”). If you have to stop taking the drug, the doctor will gradually lower your dose of Ziac over a period of 2 weeks.

Call your doctor immediately if you develop breathing problems or an extremely slow heartbeat while taking Ziac.

If you suffer from asthma or other bronchial conditions, coronary artery disease, peripheral vascular disease, or kidney or liver disease, Ziac should be used with caution.

Notify your doctor or dentist that you are taking Ziac if you have a medical emergency, and before you have surgery or dental treatment.

Ziac causes some people to become drowsy or less alert. You should not drive or operate dangerous machinery or participate in any hazardous activity until you know how the drug affects you.

This medication may mask the symptoms of low blood sugar or alter blood sugar levels. In addition, diabetics who experience a severe drop in blood sugar after taking insulin may suffer a spike in blood pressure if they are also taking Ziac.

If you have a history of severe allergic reactions that have required epinephrine, you should be aware that Ziac may make your system unresponsive to the usual effective dose of epinephrine.

If you have systemic lupus erythematosus, you should be aware that Ziac could make the symptoms worse.

Ziac could mask symptoms of an overactive thyroid. Abruptly stopping the drug could make the condition worse.

In a small number of people, Ziac has interfered with the functioning of the parathyroid, causing blood levels of calcium and phosphate to rise. In rare cases, the drug has also caused gout.

There is a slight chance that Ziac could cause a drop in blood levels of electrolytes such as potassium and magnesium. Call your doctor if you develop any of the following: drowsiness, dry mouth, excessive thirst, low blood pressure, muscle pains or cramps, rapid heartbeat, restlessness, gastrointestinal problems such as nausea and vomiting, weakness or muscle fatigue, or an unusual decrease in urination.

Be aware that Ziac could make you more sensitive to sunlight.

Possible food and drug interactions when taking Ziac

If Ziac is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor when combining Ziac with the following:

Any other blood pressure drugs, including the calcium-blockers diltiazem, disopyramide, and verapamil
Alcohol
Barbiturate sedatives
Cholesterol-lowering drugs
Clonidine
Diabetes drugs (oral)
Disopyramide and similar drugs used to treat irregular heartbeat
Epinephrine
Guanethidine
Insulin
Lithium
Muscle relaxants such as tubocurarine
Nonsteroidal anti-inflammatory drugs such as aspirin
Norepinephrine
Painkillers such as codeine or morphine
Reserpine
Rifampin
Steroids such as prednisone

Special information if you are pregnant or breastfeeding

The effects of Ziac during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Ziac should be used only if the benefit outweighs the potential risk.

It is not known if Ziac appears in breast milk. If Ziac is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Ziac is finished.

Recommended dosage for Ziac

ADULTS

Dosage is tailored to each individual’s needs. The usual starting dose is 2.5 milligrams of bisoprolol with 6.25 milligrams of hydrochlorothiazide once a day. If this dose is ineffective, the dose may be increased every 14 days up to a maximum of 20 milligrams bisoprolol/12.5 milligrams hydrochlorothiazide once a day.

If you have asthma, bronchial problems, or kidney or liver disease, the doctor may have you take a very low starting dose. Extreme caution should be used if the dose has to be increased.

Ziac has not been adequately studied in children.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose of Ziac, seek medical attention immediately.

• Symptoms of Ziac overdose may include:
  Abnormal skin sensations, cramps in the calf muscle, congestive heart failure (marked by sudden weight gain, swelling of the legs, feet, and ankles, fatigue, and shortness of breath), confusion, decreased or increased urination, difficult or labored breathing, dizziness, drowsiness, fluid or electrolyte loss, impaired consciousness, low blood pressure, low blood sugar, nausea, shock, slow or rapid heartbeat, thirst, vomiting, weakness

Large overdoses may interfere with breathing or cause delirium, coma, or convulsions.

Generic name: Ezetimibe
Brand names: Zetia

Why is Zetia prescribed?

Zetia is a new kind of cholesterol-lowering drug. The older cholesterol-lowering drugs called “statins” reduce cholesterol by interfering with its production in the body. Zetia acts by diminishing the absorption of dietary cholesterol through the intestines.

Zetia may be taken alone or with a statin drug. Because the two drugs fight cholesterol in different ways, the Zetia/statin combination has a greater impact than either drug alone.

Cholesterol—especially “bad” LDL cholesterol—promotes clogged arteries, increasing the risk of heart attack and stroke. “Good” HDL cholesterol helps to prevent clogged arteries. Zetia lowers the bad cholesterol and raises the good. It also lowers total cholesterol readings and reduces levels of triglycerides (fats in the blood).

Cholesterol-lowering drugs are typically prescribed for people who either have heart disease or are in danger of developing it. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it’s 190.

Most important fact about Zetia

Doctors usually prescribe cholesterol-lowering drugs only after changes in lifestyle have failed to bring cholesterol down to a healthy level. These changes include following a diet low in fat and cholesterol and high in fiber, shedding excess weight, and getting more exercise. It’s important to remember that drug therapy is a supplement to—not a substitute for—these other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program recommended by your doctor.

How should you take Zetia?

You can take Zetia with or without food. If the doctor has also prescribed a statin drug, you can take Zetia at the same time. If you are also taking colestipol, cholestyramine, or colesevelam, take Zetia at least 2 hours before or 4 hours after taking the other medication.

• If you miss a dose…
  Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.

• Storage instructions…
  Store at room temperature. Protect from moisture.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Zetia.

• Side effects may include:
  Abdominal pain, back pain, diarrhea, joint pain, sinusitis

Other side effects that occur when Zetia is taken with a statin drug include chest pain, dizziness, headache, muscle pain, and upper respiratory infection.

Certain allergic reactions such as hives have also occurred.

Why should Zetia not be prescribed?

If Zetia causes an allergic reaction, you’ll be unable to use it. Combined therapy with Zetia and a statin drug should be avoided if you have a liver condition or are pregnant or nursing.

Special warnings about Zetia

Zetia is not recommended for people with moderate to severe liver disease, or for children under 10.

Possible food and drug interactions when taking Zetia

Do not combine Zetia with the cholesterol-lowering drugs called fibrates, including Lopid and Tricor. Check with your doctor before combining Zetia with cyclosporine.

Special information if you are pregnant or breastfeeding

Zetia should be taken during pregnancy only if its benefits outweigh the potential risk to the baby. If you are pregnant or planning to become pregnant, check with your doctor immediately.

Statin drugs pose a definite risk to the baby, so you should never add a statin drug to Zetia therapy during pregnancy.

It’s not known whether Zetia makes its way into breast milk. The drug is recommended only if its benefits are thought to outweigh the potential risk.

Recommended dosage for Zetia

The recommended dose is 10 milligrams once a day.

Overdosage

There is no experience with Zetia overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Generic name: Zestril
Brand names: Prinivil, Zestril

Why is Zestril prescribed?

Zestril is used in the treatment of high blood pressure. It is effective when used alone or when combined with other high blood pressure medications. It may also be used with other medications in the treatment of heart failure, and may be given within 24 hours of a heart attack to improve chances of survival.

Zestril is a type of drug called an ACE inhibitor. It works by reducing production of a substance that increases salt and water retention in your body.

Most important fact about Zestril

If you have high blood pressure, you must take Zestril regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Zestril; and you must continue taking it even if you are feeling well. Zestril does not cure high blood pressure; it merely keeps it under control.

How should you take Zestril?

Zestril can be taken with or without food. Take it exactly as prescribed. Stopping Zestril suddenly could cause your blood pressure to rise.

• If you miss a dose…
  Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

• Storage instructions…
  Store at room temperature, with the container sealed and dry. Avoid excessive heat or freezing cold.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zestril.

• Side effects may include:
  Chest pain, cough, diarrhea, dizziness, headache, low blood pressure

Why should Zestril not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Zestril or other ACE inhibitors, you should not take Zestril. You should also avoid Zestril if you suffered angioedema (swelling of the face, lips, tongue, throat, intestines, arms, or legs) during previous treatment with an ACE inhibitor, or have a tendency to develop the condition for any other reason. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Zestril

If you develop swelling of your face, lips, tongue, throat, intestines, arms, or legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.

If you are being given bee or wasp venom to guard against future reactions, you may have a severe reaction to Zestril.

If you have congestive heart failure or other heart problems, a kidney disorder, or a connective tissue disease such as lupus, you should use Zestril with caution. Your doctor may perform periodic blood tests while you are taking Zestril.

If you are taking Zestril, a complete assessment of your kidney function should be done and kidney function should continue to be monitored. Zestril is used with great caution after a heart attack if the patient also has kidney problems.

This drug also should be used with caution if you are on dialysis. There have been reports of extreme allergic reactions during dialysis in people taking ACE inhibitor medications such as Zestril.

If you are taking high doses of a diuretic (water pill) and Zestril, you may develop excessively low blood pressure. This problem is also more likely if you are being treated for heart failure.

Zestril may cause some people to become dizzy, light-headed, or faint, especially if they have heart failure or are taking a water pill at the same time. Do not drive, operate dangerous machinery, or participate in any hazardous activity that requires full mental alertness until you are certain Zestril does not have this effect on you.

If you develop chest pain, sore throat, fever, and chills contact your doctor for medical attention. It could indicate a more serious condition.

If your skin and the whites of your eyes turn yellow, stop taking the medication and contact your doctor.

Avoid salt substitutes that contain potassium. Limit your consumption of potassium-rich foods such as bananas, prunes, raisins, orange juice, and whole and skim milk. Ask your doctor for advice on how much of these foods to consume.

Excessive sweating, dehydration, severe diarrhea, or vomiting could cause you to lose too much water and cause your blood pressure to drop dangerously.

Possible food and drug interactions when taking Zestril

If Zestril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zestril with any of the following:

Nonsteroidal anti-inflammatory drugs
Lithium
Potassium preparations
Water pills that may or may not leave potassium in the body

Special information if you are pregnant or breastfeeding

If it is taken during the final 6 months of pregnancy, Zestril can cause birth defects, prematurity, and death in the fetus and newborn. If you are pregnant or plan to become pregnant and are taking Zestril, contact your doctor immediately to discuss the potential hazard to your unborn child. Zestril may appear in breast milk and could affect a nursing infant. If Zestril is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Zestril is finished.

Recommended dosage for Zestril

ADULTS

High Blood Pressure

For people not on water pills (diuretics), the initial starting dose is usually 10 milligrams, taken 1 time a day. Your doctor will increase the dosage until your blood pressure is under control. The long-term dosage usually ranges from 20 to 40 milligrams a day, taken in a single dose.

Diuretic use should, if possible, be stopped before using Zestril. If not, your physician may give an initial dose of 5 milligrams under supervision before any further medication is prescribed.

People with kidney disorders must be carefully monitored, and dosages will be adjusted to the individual’s needs, depending on kidney function.

Heart Failure

For this condition, Zestril is usually prescribed along with diuretics and digitalis. The recommended starting dose is 5 milligrams once a day, with the first dose taken under your doctor’s supervision. The doctor may increase the dose by up to 10 milligrams at intervals of no less than 2 weeks. Typical long-term dosages range from 5 to 40 milligrams taken once a day.

Heart Attack

The usual dose is 5 milligrams within the first 24 hours after a heart attack, then 5 milligrams 24 hours later, 10 milligrams 48 hours later, and, finally, 10 milligrams once a day for 6 weeks. If low blood pressure is a problem, the doctor may recommend a lower dosage.

CHILDREN 6 YEARS OR OLDER

High Blood Pressure

The usual starting dose is 0.07 milligrams per day up to a total of 5 milligrams per day.

Zestril is not recommended in children younger than 6 years old or in children with poor kidney function.

OLDER ADULTS

The physician will adjust the dosage carefully, according to the individual’s needs.

Overdosage

Any medication taken in excess can cause symptoms of overdose. If you suspect an overdose, seek medical attention immediately.

A severe drop in blood pressure is the primary sign of a Zestril overdose.