Trimethobenzamide hydrochloride
30/06/10
Brand names: Tigan
Why is Trimethobenzamide hydrochloride prescribed?
Tigan is prescribed to control nausea and vomiting.
Most important fact about Trimethobenzamide hydrochloride
Antiemetics (drugs that prevent or lessen nausea and vomiting) are not recommended for the treatment of simple vomiting in children. Use of Tigan in children should be limited to prolonged vomiting caused by a known disease. Tigan is thought to have an aggravating effect on Reye’s syndrome (a potentially fatal childhood disease of the brain that sometimes strikes after a viral infection such as chickenpox). In addition, some of Tigan’s side effects can actually be confused with the symptoms of Reye’s syndrome.
How should you take Trimethobenzamide hydrochloride?
Take Trimethobenzamide hydrochloride exactly as prescribed.
If you are using the suppository form of Tigan and find it is too soft to insert, you can firm it up by chilling it in the refrigerator for about 30 minutes or running cold water over it before removing the wrapper.
To insert a suppository, first remove the wrapper and moisten the suppository with cold water. Then lie down on your side and use a finger to push the suppository well up into the rectum.
- If you miss a dose…
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
- Storage instructions…
Store away from heat, light, and moisture.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Tigan.
- Side effects may include:
Allergic-type skin reactions, blood disorders, blurred vision, coma, convulsions, depression, disorientation, dizziness, drowsiness, headache, muscle cramps, severe muscle spasm, tremors, yellowed eyes and skin
Why should Trimethobenzamide hydrochloride not be prescribed?
If you are sensitive to or have ever had an allergic reaction to Tigan do not take Trimethobenzamide hydrochloride. Do not use the suppositories if you are allergic to benzocaine or other local anesthetics. Make sure your doctor is aware of any drug reactions you have experienced.
Do not use suppositories in premature or newborn infants.
Special warnings about Trimethobenzamide hydrochloride
Tigan may cause you to become drowsy or less alert. Do not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how you respond to Trimethobenzamide hydrochloride.
During illnesses such as high fever, inflammation of the brain, inflammation of the digestive tract, or dehydration, Tigan should be used with caution, especially in children, older adults, and anyone in a run-down condition. Under these circumstances, the drug is more likely to cause severe reactions such as convulsions and coma.
Severe vomiting should not be treated with Tigan alone. Your doctor should emphasize restoration of body fluids, the relief of fever, and the relief of the disease causing the vomiting. However, the overconsumption of fluids may result in cerebral edema (excessive accumulation of fluid in the brain).
The antinausea effects of Tigan may make it difficult to diagnose such conditions as appendicitis and may mask signs of drug poisoning due to overdosage of other drugs.
Possible food and drug interactions when taking Trimethobenzamide hydrochloride
The use of alcohol in combination with Trimethobenzamide hydrochloride may produce an unfavorable reaction.
Caution should be exercised when taking Tigan in combination with central nervous system drugs such as phenothiazines (tranquilizers and antiemetics), barbiturates such as phenobarbital, and drugs derived from belladonna, such as Donnatal, if you are dehydrated or have a severe disease with fever, inflammation of the stomach, intestines, or brain.
Special information if you are pregnant or breastfeeding
The effects of Tigan during pregnancy or breastfeeding have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. If you are breastfeeding your baby, consult your doctor before taking Trimethobenzamide hydrochloride.
Recommended dosage for Trimethobenzamide hydrochloride
Dosage will be adjusted by your doctor according to your illness, the severity of your symptoms, and how well you do on the drug.
ADULTS
Capsules
The usual dosage is one 300-milligram capsule taken 3 or 4 times per day, as determined by your doctor.
Suppositories
The recommended dosage is 1 suppository (200 milligrams) inserted into the rectum 3 or 4 times per day, as determined by your doctor.
CHILDREN
Capsules
The usual dosage for children weighing 30 to 90 pounds is one or two 100-milligram capsules taken 3 or 4 times per day, as determined by the doctor.
Suppositories
The usual dosage for children weighing under 30 pounds is half a suppository (100 milligrams), inserted into the rectum 3 or 4 times a day, as determined by your doctor.
The usual dosage for children weighing 30 to 90 pounds is one-half to one 200-milligram suppository rectally 3 or 4 times a day, as determined by the doctor.
Pediatric Suppositories
The usual dosage for children weighing under 30 pounds is 1 suppository (100 milligrams) rectally 3 or 4 times a day, as determined by the doctor.
The usual dosage for children weighing 30 to 90 pounds is 1 to 2 suppositories (100 milligrams to 200 milligrams) rectally 3 or 4 times a day, as determined by the doctor.
Overdosage
Although no specific information is available, any medication taken in excess can have serious consequences. If you suspect a Tigan overdose, seek medical attention immediately.
Trileptal
30/06/10
Generic name: Oxcarbazepine
Brand names: Trileptal
Why is Trileptal prescribed?
Trileptal helps reduce the frequency of partial epileptic seizures, a form of epilepsy in which neural disturbances are limited to a specific region of the brain and the victim remains conscious throughout the attack. Trileptal may be prescribed by itself to treat the problem in adults. It can also be used in combination with other seizure medications in adults and in children as young as four years old.
Most important fact about Trileptal
Trileptal can cause drowsiness, dizziness, and loss of coordination, which could impair your ability to drive a vehicle or operate dangerous machinery. Do not attempt hazardous activities until you know how the drug affects you.
How should you take Trileptal?
Take Trileptal exactly as prescribed by your doctor. Stopping Trileptal suddenly could cause an increase in the frequency of your seizures. Trileptal may be taken with or without food.
Trileptal is available in tablets and an oral suspension, which can be used interchangeably. To administer a dose of the oral suspension, proceed as follows:
- Shake the bottle well and remove the cap.
- Push the plunger all the way down in the dosing syringe provided with the bottle.
- With the bottle upright, push the syringe firmly into the plastic adapter on the neck of the bottle.
- With the syringe in place, turn the bottle upside down.
- Slowly pull the plunger out until a small amount of medicine enters the syringe. Push the plunger back in far enough to force out any large air bubbles trapped in the syringe.
- Slowly pull the plunger out until the top edge of the black ring is level with the marker for the prescribed dose.
- Turn the bottle upright and twist the syringe free from the plastic adapter.
- Push the plunger to empty the syringe. The medicine can be dropped directly into the mouth or into a small glass of water. If using water, stir the medicine, then drink the entire glass.
- Rinse the syringe with warm water and allow it to dry. Replace the cap on the bottle.
- If you miss a dose…
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once. If you miss more than one dose in a day, check with your doctor.
- Storage instructions…
Store in a tightly closed container at room temperature.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Trileptal.
- Side effects may include:
Abnormal gait, dizziness, double vision, headache, involuntary movement of the eyeballs, nausea, sleepiness, tremor, uncoordinated muscle movement, visual disturbances, vomiting, weakness
Why should Trileptal not be prescribed?
If Trileptal gives you an allergic reaction, you won’t be able to use it.
Special warnings about Trileptal
A significant number (25 to 30 percent) of people who are sensitive to carbamazepine (Tegretol) also experience sensitivity to Trileptal. If you’ve had a problem with Tegretol, make sure the doctor is aware of it. Trileptal is prescribed under such circumstances only if there’s no better alternative.
Trileptal can lead to a loss of sodium from the blood, resulting in a serious medical condition which, left untreated, could lead to convulsions, coma, and death. Your doctor should carefully monitor your blood sodium levels during treatment with Trileptal. Alert the doctor immediately if you develop warning signs such as nausea, headache, sluggishness, confusion, loss of feeling, or an increase in the frequency or severity of seizures.
Trileptal may cause increased skin sensitivity, fever, and rash. If you are experiencing any of these symptoms, talk to your doctor immediately.
If you have kidney disease, your doctor will prescribe a lower dosage of Trileptal. Be sure your doctor knows your medical history before you start therapy.
Possible food and drug interactions when taking Trileptal
Alcohol can intensify the sedative effects of Trileptal. Avoid alcohol while taking Trileptal.
If Trileptal is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Trileptal with the following:
Calcium channel blockers such as verapamil (Calan) or felodipine (Plendil)
Carbamazepine (Tegretol)
Phenobarbital
Phenytoin (Dilantin)
Oral contraceptives
Valproic acid (Depakene)
Special information if you are pregnant or breastfeeding
Although it’s not known for sure, there is good reason to believe that Trileptal can cause birth defects. If you are pregnant or are planning to become pregnant, tell your doctor immediately. Trileptal should be used during pregnancy only if the potential benefits justify the risk.
Trileptal appears in breast milk and could cause serious side effects in a nursing infant. Check with your doctor. You’ll probably need to make a choice between breast feeding and continuing your Trileptal therapy.
Recommended dosage for Trileptal
ADULTS
Trileptal taken alone
The usual starting dose is 300 milligrams twice daily. Your doctor may gradually increase the dose to 600 milligrams twice daily. In people with kidney disorders, the starting dose is 150 milligrams twice daily.
When changing from another antiepileptic medication to Trileptal
The usual starting dose is 300 milligrams twice daily. Your doctor will gradually increase the dose over a period of 2 to 4 weeks, while reducing the other medication over a period of 3 to 6 weeks. The final dosage of Trileptal is typically 1,200 milligrams twice daily.
Trileptal combined with another antiepileptic medication
The usual starting dose is 300 milligrams twice daily. Your doctor may increase the dose to 600 milligrams twice daily.
CHILDREN 4 TO 16 YEARS OLD
For children the dosage of Trileptal is based on body weight.
Trileptal taken alone
Your child’s doctor will gradually increase the dose every 3 days until the most effective dose is reached. The usual dose ranges from 300 to 1,050 milligrams taken twice daily.
When changing from another antiepileptic medication to Trileptal
Your child’s doctor will gradually increase the dose of Trileptal while reducing the other medication over a period of 3 to 6 weeks. The doctor will increase the dose of Trileptal weekly until the most effective dose is reached. The usual dose ranges from 300 to 1,050 milligrams taken twice daily.
Trileptal combined with another antiepileptic medication
After a 2-week buildup, the dosage typically ranges from 450 to 900 milligrams taken twice daily.
Overdosage
There is little information on Trileptal overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.
Trihexyphenidyl hydrochloride
30/06/10
Triglide
30/06/10
Generic name: Fenofibrate
Brand names: Triglide
Why is Triglide prescribed?
Triglide is used, along with diet and exercise, to treat people with very high levels of triglycerides (a fatty substance in the blood). Triglide also improves cholesterol levels by lowering total cholesterol—including “bad” LDL cholesterol—and raising “good” HDL cholesterol. It works by promoting the dissolution and elimination of fat particles in the blood.
It’s important to remember that Triglide is a supplement to, not a replacement for, other treatment measures such as diet and exercise. To get the full benefit of Triglide, you need to stick to the diet, exercise program, and other therapies your doctor prescribes.
Most important fact about Triglide
Drugs such as Triglide have caused rare cases of a muscle-wasting disease called rhabdomyolysis. The chances of this problem rise dramatically when Triglide is combined with another type of cholesterol-lowering drug known as statins. Examples include atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, and simvastatin. Avoid combining Triglide with any of these drugs unless your doctor feels it’s absolutely necessary. Inform the doctor immediately if you develop muscle pain or weakness, especially if these symptoms are accompanied by fatigue or fever.
How should you take Triglide?
Triglide may be taken with or without food.
- Storage instructions…
Store at room temperature, away from light and moisture.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Triglide.
- Side effects may include:
Back pain, flu-like symptoms, headache, stomach pain, weakness
Why should Triglide not be prescribed?
Do not begin treatment with Triglide if you are allergic to any of its ingredients, or if you have kidney, liver, or gallbladder problems.
Special warnings about Triglide
Triglide has the potential to cause gallstones. Your doctor will discontinue the drug if gallstones develop.
Triglide may also affect liver function. Your doctor should perform periodic blood tests to monitor the health of your liver.
Triglide has not been tested in children.
Possible food and drug interactions when taking Triglide
If Triglide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Triglide with the following:
Blood thinners such as warfarin
Cyclosporine
Cholesterol-lowering drugs known as statins (see “Most important fact about Triglide”)
Special information if you are pregnant or breastfeeding
The effects of Triglide during pregnancy are unknown. Talk with your doctor before taking Triglide if you are pregnant or plan to become pregnant. It is strongly advised to avoid breastfeeding while taking Triglide.
Recommended dosage for Triglide
ADULTS
The usual starting dose is 50 to 160 milligrams once a day. The maximum dose is 160 milligrams per day.
Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Trifluoperazine hydrochloride
30/06/10
Tricor
30/06/10
Generic name: Fenofibrate
Brand names: Lofibra, Tricor
Why is Tricor prescribed?
Tricor is used, along with a special diet, to treat people with very high levels of triglycerides (a fatty substance in the blood). Tricor also improves cholesterol levels by lowering total cholesterol—including “bad” LDL cholesterol—and raising “good” HDL cholesterol. It works by promoting the dissolution and elimination of fat particles in the blood.
Tricor is usually added to a treatment regimen only when other measures have failed to produce adequate results. Often, diet and exercise are enough to bring blood fats under control. Likewise, it’s sometimes sufficient to simply treat an underlying problem such as diabetes, underactive thyroid, kidney disease, liver dysfunction, or alcoholism. And in some cases, just discontinuing a medication is enough to do the job. For instance, certain water pills and “beta-blocker” heart medications are capable of causing a massive increase in triglyceride levels. Estrogen replacement therapy is another potential culprit.
Whatever your other treatment measures may be, it’s important to remember that Tricor is intended to supplement them, rather than replace them outright. To get the full benefit of the medication, you need to stick to the diet, exercise program, and other treatments your doctor prescribes. All these efforts to keep your cholesterol and triglyceride levels normal are important because together they may lower your risk of heart disease. If you’re judged to be at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it’s 190.
Most important fact about Tricor
Drugs such as Tricor have caused rare cases of a muscle-wasting disease called rhabdomyolysis. The chances of this problem rise dramatically when Tricor is combined with another type of cholesterol-lowering drug called statins, such as simvastatin, pravastatin, and atorvastatin. Avoid combining Tricor with any of them unless your doctor feels it’s absolutely necessary. Inform the doctor immediately if you develop muscle pain or weakness, especially if these symptoms are accompanied by fatigue or fever: You’ll probably have to stop taking Tricor.
How should you take Tricor?
Tricor should be taken with meals. If you’ve also been prescribed a cholesterol-lowering drug such as cholestyramine, take Tricor at least 1 hour before or 4 to 6 hours after the other drug to make sure Tricor is properly absorbed.
- If you miss a dose…
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.
- Storage instructions…
Store at room temperature and protect from moisture.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Tricor.
- Side effects may include:
Abdominal pain, back pain, headache, respiratory disorders
Why should Tricor not be prescribed?
You should not take Tricor if you have liver or gallbladder disease, or severe kidney problems. You’ll also have to avoid Tricor if it gives you an allergic reaction.
Special warnings about Tricor
Tricor has the potential to cause gallstones. Your doctor will discontinue the drug if gallstones develop.
Tricor may also affect liver function. Your doctor should perform periodic blood tests to monitor the health of your liver.
Tricor has not been tested in children.
Possible food and drug interactions when taking Tricor
If Tricor is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Tricor with the following:
Blood thinners such as warfarin
The cholesterol-lowering drug cholestyramine
Cyclosporine
Cholesterol-lowering drugs known as statins (atorvastatin, pravastatin, simvastatin, and others)
Special information if you are pregnant or breastfeeding
Pregnancy tests have not been conducted in humans, but high doses of Tricor have proven harmful in animal studies. If you are pregnant or plan to become pregnant, inform your doctor immediately.
Tricor should not be used in nursing mothers. If Tricor is essential to your health, your doctor will advise you to stop nursing your baby.
Recommended dosage for Tricor
ADULTS
High cholesterol levels or a combination of high cholesterol and high triglycerides
The initial dose of Tricor is 160 milligrams per day.
High triglyceride levels
The starting dose of Tricor ranges from 54 to 160 milligrams per day. Your doctor may increase the dose every 4 to 8 weeks if your triglycerides do not improve. The maximum dose of Tricor is 160 milligrams a day.
OLDER ADULTS
The starting dose of Tricor for older adults and those with poor kidney function is 54 milligrams per day.
Overdosage
There is no information on the effects of a Tricor overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Triavil
30/06/10
Generic name: Amitriptyline hydrochloride with Perphenazine
Brand names: Triavil
Why is Triavil prescribed?
Triavil is used to treat anxiety, agitation, and depression. Triavil is a combination of a tricyclic antidepressant (amitriptyline) and a tranquilizer (perphenazine).
Triavil can also help people with schizophrenia (distorted sense of reality) who are depressed and people with insomnia, fatigue, loss of interest, loss of appetite, or a slowing of physical and mental reactions.
Most important fact about Triavil
Triavil may cause tardive dyskinesia—a condition marked by involuntary muscle spasms and twitches in the face and body. This condition may be permanent and appears to be most common among the elderly, especially women. Ask your doctor for information about this possible risk.
How should you take Triavil?
Triavil may be taken with or without food. You should not take it with alcohol. In addition, Triavil should not be taken within 2 hours of antacids or diarrhea medication.
- If you miss a dose…
Take it as soon as you remember. If it is within 2 hours of your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
- Storage instructions…
Store at room temperature in a tightly closed container. Protect Triavil 2-10 tablets from light.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Triavil.
- Side effects may include:
Disorientation, dry mouth, high or low blood pressure, nervous system disorders, sedation
Why should Triavil not be prescribed?
You should not be using Triavil if you are taking drugs that slow down the central nervous system, including alcohol, barbiturates, analgesics, antihistamines, or narcotics.
Triavil should not be used if you are recovering from a recent heart attack, or if you have an abnormal bone marrow condition. Avoid Triavil if you have ever had an allergic reaction to phenothiazines or amitriptyline.
People who are taking antidepressant drugs known as MAO inhibitors (including Nardil and Parnate) should not take Triavil.
Special warnings about Triavil
In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Triavil or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Triavil is not approved for use in children.
Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Triavil and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly—especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior—and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.
Before using Triavil, tell your doctor if you have ever had the following: glaucoma (high pressure in the eye); difficulty urinating; breast cancer; breathing problems; seizures; heart, liver, kidney, or thyroid disease; or if you are exposed to extreme heat or pesticides. Be aware that Triavil may mask signs of brain tumor, intestinal blockage, and overdose of other drugs.
Nausea, headache, and a general ill feeling can result if you suddenly stop taking Triavil. Follow your doctor’s instructions closely when discontinuing Triavil. If your dose is gradually reduced, you may experience irritability, restlessness, and dream and sleep disturbances, but these effects will not last.
This drug may impair your ability to drive a car or operate potentially dangerous machinery. Do not participate in any activities that require full alertness if you are unsure about your ability.
If you develop a fever that has no other cause, stop taking Triavil and call your doctor.
Drugs such as Triavil are known to trigger a potentially fatal condition known as Neuroleptic Malignant Syndrome (NMS). Symptoms include high fever, muscle rigidity, unstable blood pressure, rapid or irregular heartbeat, and excessive sweating. If any of these symptoms develop, contact your doctor immediately.
Triavil could make you more sensitive to sunlight. Be careful to stay out of the sun, wear protective clothing, and use sunblock.
Triavil could also trigger a manic episode in people with bipolar disorder, although the drug’s tranquilizing effects seem to reduce this risk.
While taking Triavil, you may feel dizzy or light-headed or actually faint when getting up from a lying or sitting position. If getting up more slowly doesn’t help or if the problem continues, contact your doctor.
Tell the doctor or dentist you’re taking Triavil before having any surgery, dental work, or diagnostic procedure. Triavil could interact with anesthetics, muscle relaxants, and other drugs used during surgical procedures.
Possible food and drug interactions when taking Triavil
Triavil contains the same active ingredients as Elavil and Trilafon and should not be used with these drugs.
If Triavil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Triavil with the following:
Airway-opening drugs such as Proventil
Antidepressants classified as MAO inhibitors, including Nardil and Parnate
Antidepressants that boost serotonin, including fluvoxamine, Paxil, Prozac, and Zoloft
Antiseizure drugs such as Dilantin
Antihistamines such as Benadryl
Antispasmodic drugs such as Bentyl
Atropine (Donnatal)
Barbiturates such as phenobarbital
Blood pressure medications
Blood-thinning drugs such as Coumadin
Cimetidine (Tagamet)
Disulfiram (Antabuse)
Epinephrine (EpiPen)
Ethchlorvynol (Placidyl)
Flecainide (Tambocor)
Fluoxetine (Prozac)
Fluphenazine (Prolixin)
Furazolidone (Furoxone)
Guanethidine
Major tranquilizers such as Haldol
Narcotic analgesics such as Percocet
Phosphorus insecticides
Propafenone (Rythmol)
Quinidine
Thioridazine (Mellaril)
Thyroid medications such as Synthroid
Extreme drowsiness and other potentially serious effects can result if Triavil is combined with alcohol or other central nervous system depressants such as narcotics, painkillers, and sleep medications.
Special information if you are pregnant or breastfeeding
Triavil may cause false-positive results on pregnancy tests. Triavil should not be used by pregnant women or mothers who are breastfeeding.
Recommended dosage for Triavil
Your doctor will individualize your dose.
You should not take more than 4 tablets of Triavil 4-50 or 8 tablets of any other strength in one day. It may be a few days to a few weeks before you notice any improvement.
ADULTS
For Non-Psychotic Anxiety and Depression
The usual dose is 1 tablet of Triavil 2-25 or 4-25 taken 3 or 4 times a day, or 1 tablet of Triavil 4-50 taken twice a day.
For Anxiety in People with Schizophrenia
The usual dose is 2 tablets of Triavil 4-25 taken 3 times a day. Your doctor may tell you to take another tablet of Triavil 4-25 at bedtime, if needed.
If you need to keep taking Triavil, your doctor will probably have you take 1 tablet of Triavil 2-25 or 4-25 from 2 to 4 times a day or 1 tablet of Triavil 4-50 twice a day.
CHILDREN
Children should not use Triavil.
OLDER ADULTS AND ADOLESCENTS
For Anxiety
The usual dose is 1 tablet of Triavil 4-10, taken 3 or 4 times a day. People in these age groups usually take Triavil at lower doses.
Overdosage
Any medication taken in excess can have serious consequences. An overdose of Triavil can be fatal. If you suspect an overdose, seek medical help immediately.
- Symptoms of Triavil overdose may include:
Abnormalities of posture and movements, agitation, coma, convulsions, dilated pupils, drowsiness, extreme low body temperature, eye movement problems, high fever, heart failure, overactive reflexes, rapid or irregular heartbeat, rigid muscles, stupor, very low blood pressure, vomiting
Triamcinolone acetonide
30/06/10
Brand names: Nasacort AQ, Nasacort, Azmacort
Why is Triamcinolone acetonide prescribed?
Azmacort and Nasacort are metered-dose inhalers containing the anti-inflammatory steroid medication, triamcinolone acetonide; Nasacort AQ is a metered-dose pump spray. Azmacort is used as long-term therapy to control bronchial asthma attacks. Nasacort and Nasacort AQ are prescribed to relieve the symptoms of hay fever and other nasal allergies in adults and children 6 years and older. Nasacort is also used in the treatment of nasal polyps (projecting masses of tissue in the nose).
Most important fact about Triamcinolone acetonide
Azmacort does not provide rapid relief in an asthma attack. Instead, it reduces the frequency and severity of attacks when taken on a regular basis. For quick relief, you must still use airway-opening medications.
How should you take Triamcinolone acetonide?
Take these drugs on a regular daily basis, exactly as prescribed. With Azmacort and Nasacort, you should begin to see improvement after a week, although it may take 2 weeks or more to achieve the greatest benefit. Nasacort AQ should begin to produce results on the first day, but will take a week to yield maximum benefit.
Shake the canister or bottle before each use. The Azmacort inhaler must be primed with 2 activations whenever it has been unused for more than 3 days. Do not use an Azmacort inhaler more than 240 times. Discard the Nasacort canister after 100 inhalations and the Nasacort AQ bottle after 120 actuations.
If the drug irritates your throat, gargling and rinsing your mouth with water after each dose can help to relieve the problem.
If you are using a bronchodilator inhalant, it should be used before the Azmacort inhalant to derive the best effects from Triamcinolone acetonide. Use of the two inhalers should be separated by several minutes.
Do not spray Nasacort directly onto the bone that separates the nostrils. Avoid spraying either medication in your eyes.
Illustrated instructions for use are available with the product.
- If you miss a dose…
Use it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
- Storage instructions…
Store at room temperature. Since the contents of the aerosol inhalant are under pressure, do not puncture the container and do not use or store the medication near heat or open flame. Exposure to temperatures above 120 degrees F. may cause the container to explode.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking these medications.
AZMACORT
- More common side effects of Azmacort may include:
Back pain, flu symptoms, headache, sinus inflammation, sore throat
NASACORT
- More common side effects of Nasacort may include:
Headache
- Side effects of Nasacort in children aged 6 to 11 may include:
Cough, ear inflammation, fever, indigestion, nausea, nosebleed, throat discomfort
NASACORT AQ
- Side effects of Nasacort AQ may include:
Headache, nosebleed, stuffy nose
- Side effects of Nasacort AQ in children aged 6 to 11 may include:
Asthma, headache, infection, earache, sinus problems, vomiting
Why should Triamcinolone acetonide not be prescribed?
Do not use any of these medications if you are allergic to or sensitive to any of the ingredients. Do not use Azmacort if:
- Your asthma can be controlled with airway openers and other non-steroid medications.
- You require only occasional steroid treatment for asthma. (Azmacort is not for treatment of prolonged, severe asthma attacks where fast-acting measures are required.)
- You have bronchitis not associated with asthma.
Special warnings about Triamcinolone acetonide
Your doctor will see that your asthma is reasonably under control before starting you on Azmacort. For about a week, he or she will have you take Azmacort along with your usual dose of oral steroid. After that, you will gradually take less and less of the oral drug. If you develop joint or muscular pain, weariness, and depression, contact your doctor immediately. If you feel light-headed or find that you are losing weight, also tell your doctor.
If you are using Azmacort and your airway-opening medication is not effective during an asthma attack, contact your doctor immediately. Also get medical help immediately if your wheezing gets worse after a dose of Azmacort.
The use of triamcinolone acetonide may cause a yeast-like fungal infection in the mouth and throat (Azmacort) or nose and throat (Nasacort and Nasacort AQ). If you suspect a fungal infection, notify your doctor. Treatment with antifungal medication may be necessary.
People using steroid medications such as these are more susceptible to infection. Chickenpox and measles, for example, can be far more serious for children and for adults who have not had them. Try to avoid exposure, but if you are exposed, inform your doctor. Medication may be needed.
Switching from steroid tablet therapy to Azmacort Inhaler may allow allergic conditions to surface that were previously controlled by the tablets. These include rhinitis (inflammation of the inside of the nose), conjunctivitis (pinkeye), and eczema.
If your child is using any of these medications, your doctor will watch to be sure he or she is growing properly. If you have just had an operation, or if you are experiencing extreme stress, your doctor will watch you closely.
Use these medications with extreme caution if you have tuberculosis, an untreated infection, or a herpes infection of the eye.
If your symptoms do not improve after 3 weeks, or if they get worse, contact your doctor. If you are using Nasacort or Nasacort AQ, also notify your doctor if you develop nosebleeds or notice nasal irritation, burning, or stinging after using the medication.
Use Nasacort or Nasacort AQ with caution if you have not fully healed from nasal ulcers, or an injury to your nose. Steroids can slow wound healing, and there have been rare cases of perforation inside the nose caused by inhaled steroids.
Possible food and drug interactions when taking Triamcinolone acetonide
Inhaled steroids such as Azmacort, Nasacort, and Nasacort AQ are not recommended for long-term use while you are taking prednisone.
Special information if you are pregnant or breastfeeding
The effects of triamcinolone acetonide during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether triamcinolone acetonide appears in breast milk. If Triamcinolone acetonide is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Triamcinolone acetonide is finished.
Recommended dosage for Triamcinolone acetonide
AZMACORT
The Azmacort Inhaler unit is for oral inhalation only.
Adults
The usual dose is 2 inhalations (about 200 micrograms), taken 3 or 4 times a day or 4 inhalations taken twice a day. The daily dose should not exceed 16 inhalations.
Children 6 to 12 Years of Age
The usual dose is 1 or 2 inhalations (100 to 200 micrograms), taken 3 or 4 times a day or 2 to 4 inhalations taken twice a day. The daily dose should not exceed 12 inhalations.
Children Under 6 Years of Age
The safety and effectiveness of Triamcinolone acetonide have not been established in children under 6 years of age.
NASACORT
Adults and Children Aged 12 and Older
The usual starting dose is 220 micrograms a day, taken as 2 sprays in each nostril once a day. (One spray is 55 micrograms.) If necessary, your doctor may increase the dose up to 440 micrograms a day, taken all at once, twice a day, or 4 times a day. Once Nasacort has started to work, your doctor may decrease the dose to 110 micrograms a day.
Children 6 to 11 Years of Age
The usual starting dose is 2 sprays in each nostril once a day, for a total of 220 micrograms a day. Your doctor will adjust the dose to best suit the child.
Children Under 6 Years of Age
The safety and effectiveness of Nasacort in children under 6 years of age have not been established.
NASACORT AQ
Adults and Children Aged 12 and Older
The usual starting dose is 220 micrograms taken as 2 sprays in each nostril once a day. Once your symptoms are under control, your doctor may reduce the dose to 110 micrograms a day.
Children Aged 6 to 12
The recommended starting dose is 110 micrograms per day taken as 1 spray in each nostril once a day. The maximum dose is 220 micrograms per day taken as 2 sprays in each nostril once a day.
Children Under 6 Years of Age
Safety and effectiveness have not been established.
NASACORT HFA
Adults and Children Aged 12 and Older
The starting dose is 220 micrograms per day, given as 2 sprays in each nostril once daily.
Children Aged 6 to 11
The recommended starting dose is 220 micrograms per day, given as 2 sprays in each nostril once daily.
Children Under 6 Years of Age
Safety and effectiveness have not been established.
Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek emergency medical treatment immediately.
An overdose is likely to be signaled by an increase in side effects. Accidental contact with the contents of the canister would most likely irritate your nose and give you a headache.
Overuse of Nasacort AQ may upset your stomach and intestines.
Continual overuse of Azmacort inhalation aerosol could lower your resistance; cause weakness; wasting, or swelling; and interfere with healing.
Trazodone hydrochloride
30/06/10
Brand names: Desyrel
Why is Trazodone hydrochloride prescribed?
Desyrel is prescribed for the treatment of depression.
Most important fact about Trazodone hydrochloride
Desyrel does not provide immediate relief. It may take up to 4 weeks before you begin to feel better, although most patients notice improvement within 2 weeks.
How should you take Trazodone hydrochloride?
Take Desyrel shortly after a meal or light snack. You may be more apt to feel dizzy or light-headed if you take the drug before you have eaten.
Desyrel may cause dry mouth. Sucking on a hard candy, chewing gum, or melting bits of ice in your mouth can relieve the problem.
- If you miss a dose…
Take it as soon as you remember. If it is within 4 hours of your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.
- Storage instructions…
Store at room temperature in a tightly closed container away from light and excessive heat.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Desyrel.
- Side effects may include:
Abdominal or stomach disorder, aches or pains in muscles and bones, anger or hostility, blurred vision, brief loss of consciousness, confusion, constipation, decreased appetite, diarrhea, dizziness or light-headedness, drowsiness, dry mouth, excitement, fainting, fast or fluttery heartbeat, fatigue, fluid retention and swelling, headache, inability to fall or stay asleep, low blood pressure, nasal or sinus congestion, nausea, nervousness, nightmares or vivid dreams, tremors, uncoordinated movements, vomiting, weight gain or loss
Why should Trazodone hydrochloride not be prescribed?
If you are sensitive to or have ever had an allergic reaction to Desyrel or similar drugs, you should not take Trazodone hydrochloride. Make sure your doctor is aware of any drug reactions you have experienced.
Special warnings about Trazodone hydrochloride
In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Desyrel or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Desyrel has not been studied in children or adolescents and is not approved for treating anyone less than 18 years old.
Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Desyrel and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly—especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior—and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.
Desyrel may cause you to become drowsy or less alert and may affect your judgment. Therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how Trazodone hydrochloride affects you.
Desyrel has been associated with priapism, a persistent, painful erection of the penis. Men who experience prolonged or inappropriate erections should stop taking Trazodone hydrochloride and consult their doctor.
Notify your doctor or dentist that you are taking Trazodone hydrochloride if you have a medical emergency, and before you have surgery or dental treatment. Your doctor will ask you to stop using the drug if you are going to have elective surgery.
Be careful taking Trazodone hydrochloride if you have heart disease. Desyrel can cause irregular heartbeats.
Possible food and drug interactions when taking Trazodone hydrochloride
Desyrel may intensify the effects of alcohol. Do not drink alcohol while taking Trazodone hydrochloride.
If Desyrel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Desyrel with the following:
Antidepressant drugs known as MAO inhibitors, including phenelzine and tranylcypromine
Other antidepressants such as fluoxetine and desipramine
Barbiturates such as secobarbital
Central nervous system depressants such as meperidine and triazolam
Chlorpromazine
Digoxin
Drugs for high blood pressure such as clonidine and guanabenz
Phenytoin
Warfarin
Special information if you are pregnant or breastfeeding
The effects of Desyrel during pregnancy have not been adequately studied. If you are pregnant or planning to become pregnant, inform your doctor immediately. This medication may appear in breast milk. If treatment with Trazodone hydrochloride is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.
Recommended dosage for Trazodone hydrochloride
ADULTS
The usual starting dosage is a total of 150 milligrams per day, divided into 2 or more smaller doses. Your doctor may increase your dose by 50 milligrams per day every 3 or 4 days. Total dosage should not exceed 400 milligrams per day, divided into smaller doses. Once you have responded well to the drug, your doctor may gradually reduce your dose. Because Trazodone hydrochloride makes you drowsy, your doctor may tell you to take the largest dose at bedtime.
Overdosage
Any medication taken in excess can have serious consequences. An overdose of Desyrel in combination with other drugs can be fatal. If you suspect an overdose, seek medical attention immediately.
- Symptoms of a Desyrel overdose may include:
Breathing failure, drowsiness, irregular heartbeat, prolonged, painful erection, seizures, vomiting
Travoprost
30/06/10
Brand names: Travatan
Why is Travoprost prescribed?
Travatan is an eyedrop that reduces excessive pressure in the eye (often a result of the condition called open-angle glaucoma). Travatan works by promoting drainage of the fluid that fills the eye. It is usually prescribed when you cannot use other remedies or the other drugs have not been effective.
Most important fact about Travoprost
Over a period of months or years, Travatan may permanently darken the color of your iris and eyelid. It also may increase the darkness, length, and thickness of your eyelashes. If you need Travatan in only one eye, this may cause a noticeable difference.
How should you take Travoprost?
To apply Travatan, gently pull your lower eyelid down to form a pocket then place a drop of the medication in the pouch.
Do not place Travatan in the eyes while wearing contact lenses. Remove the lenses before administering Travatan and wait 15 minutes before reinserting them.
Handle the Travatan solution carefully. Do not allow the tip of the bottle to come in contact with your eye or any surface. This could contaminate the solution and lead to an infection that seriously damages the eye.
If you need to use another eye medication along with Travatan, the drugs should be applied at least 5 minutes apart.
- If you miss a dose…
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.
- Storage instructions…
Store at room temperature. Throw away any unused medication after 6 weeks.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Travatan.
- Side effects may include:
Redness in the eye (affects 35 to 50 percent of patients), decreased visual sharpness, eye discomfort, sensation of a foreign body in the eye, eye pain or itching
Why should Travoprost not be prescribed?
You should avoid Travoprost if you are allergic to travoprost, benzalkonium chloride, or any of Travatan’s other ingredients.
Special warnings about Travoprost
Infections from contaminated eye products can lead to serious damage or even loss of vision. If you have an eye injury or infection, or if you have eye surgery, ask your doctor if you should continue to use the Travatan container.
Contact your doctor immediately if you develop any adverse eye reactions while using Travatan, especially conjunctivitis (pinkeye) and eyelid reactions.
Use Travatan with caution if you have an inflammation of the iris, or swelling of the macular part of the eye.
The safety and effectiveness of Travatan in children have not been established.
Possible food and drug interactions when taking Travoprost
No interactions have been reported.
Special information if you are pregnant or breastfeeding
Travatan has been found to cause miscarriages in animal studies. Since there are no adequate and well-controlled studies in pregnant women, Travatan should not be used if you’re pregnant or planning to become pregnant unless the benefit outweighs the potential risk to the baby.
It is not known whether Travatan appears in breast milk, but caution is advised.
Recommended dosage for Travoprost
ADULTS
Place one drop in the affected eye(s) once a day in the evening. Do not apply more often; this will decrease the effectiveness of the medication.
Overdosage
There is no information on overdosage. However, any medication taken in excess can have serious consequences. If you suspect a Travatan overdose, seek medical help immediately.