Extra Strength Mylanta Calci Tabs
30/06/10
Generic Name: calcium carbonate (KAL see um KAR boe nate)
Brand Names: Alka-Mints, Cal-Gest, Calcarb, Calci Mix, Calci-Chew, Calcium Concentrate, Calcium Liquid Softgel, Calcium Oyster Shell, Caltrate, Chooz, Extra Strength Mylanta Calci Tabs, Icar Prenatal Chewable Calcium, Maalox Antacid Barrier, Maalox Childrens’, Maalox Quick Dissolve, Maalox Quick Dissolve Maximum Strength, Maalox Regular Strength, Mylanta Child, Nephro Calci, Os-Cal 500, Oysco 500, Oyst Cal 500, Oyster Cal, Oyster Calcium, Oyster Shell, Pepto Children’s, Rolaids Sodium Free, Rolaids Soft Chew, Titralac, Tums, Tums 500, Tums E-X, Tums Kids, Tums QuikPak, Tums Ultra
What is Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body.
Calcium carbonate is used to prevent and to treat calcium deficiencies.
Calcium carbonate may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Do not take calcium carbonate or antacids that contain calcium without first asking your doctor if you also take other medicines. Calcium can make it harder for your body to absorb certain medicines. Calcium carbonate works best if you take it with food.
What should I discuss with my healthcare provider before taking Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Before taking this medication, tell your doctor if you have:
-
a history of kidney stones; or
-
a parathyroid gland disorder.
If you have any of these conditions, you may not be able to take calcium carbonate, or you may need a dose adjustment or special tests during treatment.
Talk to your doctor before taking calcium carbonate if you are pregnant. Talk to your doctor before taking calcium carbonate if you are breast-feeding a baby.
How should I take Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Calcium carbonate works best if you take it with food. Swallow the calcium carbonate tablet or capsule with a full glass of water.
The chewable tablet should be chewed before you swallow it.
Use the calcium carbonate powder as directed. Allow the powder to dissolve completely, then consume the mixture.
Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include nausea, vomiting, decreased appetite, constipation, confusion, delirium, stupor, and coma.
What should I avoid while taking Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Follow your healthcare provider’s instructions about any restrictions on food, beverages, or activity.
Extra Strength Mylanta Calci Tabs (calcium carbonate) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
-
nausea or vomiting;
-
decreased appetite;
-
constipation;
-
dry mouth or increased thirst; or
-
urinating more than usual.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs can affect Extra Strength Mylanta Calci Tabs (calcium carbonate)?
Calcium carbonate can make it harder for your body to absorb other medications you take by mouth. Tell your doctor if you are taking:
-
digoxin (Lanoxin, Lanoxicaps);
-
antacids or other calcium supplements;
-
calcitriol (Rocaltrol) or vitamin D supplements; or
-
doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).
This list is not complete and other drugs may interact with calcium carbonate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your doctor or pharmacist can provide more information about calcium carbonate.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 4.01. Revision Date: 02/26/2010 3:57:27 PM.
Exotic-HC
30/06/10
Generic Name: chloroxylenol, hydrocortisone, and pramoxine (otic) (KLOR oh ZYE nol, HYE droe KOR ti sone, pra MOX een)
Brand Names: Aero Otic HC, Cortamox, Cortane-B, Cortane-B Aqueous, Cortane-B Otic, Cortic-ND, Cyotic, Exotic-HC, Hydro Ear, IvDerm, Otirx, Oto-End, Otomar HC, Tri-Otic, Zolene HC, Zoto-HC Drops
What is Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic))?
Chloroxylenol is an antibiotic that fights bacteria.
Pramoxine is a topical anesthetic. It works by interfering with pain signals sent from the nerves to the brain.
Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.
The combination of chloroxylenol, hydrocortisone, and pramoxine otic (for the ear) are used to treat pain, and swelling caused by ear infections.
Chloroxylenol, hydrocortisone, and pramoxine otic may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic))?
Do not use this medication if you have a ruptured (torn) ear drum, or the medication could leak into the inner ear. A ruptured ear drum usually causes moderate to severe ear pain, with or without a decrease in hearing. Call your doctor if you think you have a ruptured ear drum. Your doctor will use a special scope to see any tear in your ear drum.
Before using chloroxylenol, hydrocortisone, and pramoxine, tell your doctor if you are allergic to any drugs, or if you have any type of illness or infection (other than an ear infection).
Chloroxylenol, hydrocortisone, and pramoxine otic is for use only in your ear. Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water. Ear infections may sometimes cause dizziness or a loss of balance. Be careful if you drive, operate machinery, or do anything else hazardous if you feel dizzy or off balance. Stop using this medication and call your doctor at once if you have ear drainage or discharge, severe burning or itching in your ear, or worsening pain, irritation, or rash.
Less serious side effects are more likely, and you may have none at all.
What should I discuss with my healthcare provider before using Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic))?
You should not use this medication if you are allergic to chloroxylenol, hydrocortisone, or pramoxine.
Do not use this medication if you have a ruptured (torn) ear drum, or the medication could leak into the inner ear. A ruptured ear drum usually causes moderate to severe ear pain, with or without a decrease in hearing. Call your doctor if you think you have a ruptured ear drum. Your doctor will use a special scope to see any tear in your ear drum.
Before using chloroxylenol, hydrocortisone, and pramoxine, tell your doctor if you are allergic to any drugs, or if you have any type of illness or infection (other than an ear infection).
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether chloroxylenol, hydrocortisone, and pramoxine otic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use my Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic))?
Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.
Do not use the medication in your eyes or take it by mouth. Chloroxylenol, hydrocortisone, and pramoxine otic is for use in the ears only.
For best results, remove any ear wax or other debris before using the ear drops. Ask your doctor about safe methods of ear wax removal.
To use the ear drops, first remove the cap from the dropper bottle. Lie down or tilt your head with your ear facing upward. Pull back on your ear gently to open up the ear canal. Hold the dropper upside down over your ear canal and place enough drops of the medicine in your ear to fill the ear canal.
Do not place the dropper tip into your ear, or allow the tip to touch any surface. It may become contaminated.
After using the ear drops, keep the ear tilted upward for about 5 minutes. You may also be able to soak a small cotton wick with the medication and leave it in place. Ask your doctor of pharmacist for instructions on using a cotton wick.
Wipe the dropper tip with a clean tissue. Do not wash the tip with water or soap.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Talk with your doctor if your symptoms do not improve after using this medication.
Store the ear drops at room temperature away from moisture and heat. Keep the bottle properly capped.
What happens if I miss a dose?
Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
An overdose of chloroxylenol, hydrocortisone, and pramoxine applied into the ear is not likely to cause life-threatening symptoms.
What should I avoid while using this medication?
Do not use other ear drops during treatment with chloroxylenol, hydrocortisone, and pramoxine otic without first talking to your doctor. Ear infections may sometimes cause dizziness or a loss of balance. Be careful if you drive, operate machinery, or do anything else hazardous if you feel dizzy or off balance. Chloroxylenol, hydrocortisone, and pramoxine otic is for use only in your ear. Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water.
Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic)) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
-
ear drainage or discharge;
-
severe burning or itching in your ear; or
-
worsening pain, irritation, or rash.
Less serious side effects are more likely, and you may have none at all.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect my Exotic-HC (chloroxylenol, hydrocortisone, and pramoxine (otic))?
It is not likely that other drugs you take orally or inject will have an effect on chloroxylenol, hydrocortisone, and hydrocortisone otic. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about chloroxylenol, hydrocortisone, and pramoxine otic.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:42:35 PM.
Extavia
30/06/10
Generic Name: interferon beta-1b (in ter FEAR on BAY ta 1b)
Brand Names: Betaseron, Extavia
What is interferon beta-1b?
Interferon beta-1b is made from human proteins. Interferons help the body fight viral infections.
Interferon beta-1b is used to treat relapsing multiple sclerosis (MS). This medication will not cure MS, it will only decrease the frequency of relapse symptoms.
Interferon beta-1b may also be used for other purposes other than those listed in this medication guide.
What is the most important information I should know about interferon beta-1b?
This medication may be harmful to an unborn baby, or may cause a miscarriage. Do not use interferon beta-1b if you are pregnant. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Before using interferon beta-1b, tell your doctor if you are allergic to any drugs, or if you have liver disease, a thyroid disorder, epilepsy or other seizure disorder, a bleeding or blood-clotting disorder, anemia (low red blood cells), or a history of depression or suicidal behavior.
Some patients using interferon medications have become very depressed or had thoughts of suicide. Stop using interferon beta-1b if you have symptoms of depression (sadness, crying, loss of interest in things you once liked) or if you have any thoughts of hurting yourself.
Interferon beta-1b is given as an injection under the skin, usually at bedtime every 48 hours (2 days). You may be given instructions on how to use your injections at home. You may be shown how to inject your medicine at home.
Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
To be sure this medication is not causing harmful effects, your blood and liver function will need to be tested on a regular basis. Your thyroid function may also need to be tested. Do not miss any scheduled appointments.
What should I discuss with my healthcare provider before using interferon beta-1b?
Do not use this medication if you are allergic to interferons or human albumin. Some patients using interferon medications have become very depressed or had thoughts of suicide. Stop using interferon beta-1b if you have symptoms of depression (sadness, crying, loss of interest in things you once liked) or if you have any thoughts of hurting yourself.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:
-
liver disease;
-
a thyroid disorder;
-
epilepsy or other seizure disorder;
-
a bleeding or blood-clotting disorder, such as hemophilia;
-
anemia (lack of red blood cells); or
-
a history of depression or suicidal behavior.
FDA pregnancy category C. This medication may be harmful to an unborn baby, or may cause a miscarriage. Do not use interferon beta-1b if you are pregnant. Tell your doctor if you become pregnant during treatment. It is not known whether interferon beta-1b passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Interferon beta-1b is made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How should I use interferon beta-1b?
Interferon beta-1b is given as an injection under the skin. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home.
Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
Interferon beta-1b is injected into a skin area of the thigh, stomach, buttocks, or back of the upper arm. This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Interferon beta-1b is usually given as one injection at bedtime every 48 hours (2 days). Follow the directions on your prescription label. Try to use your injections at the same time each dosing day.
Interferon beta-1b is a powder that comes in a single-use vial (bottle) with a liquid (diluent) that must be mixed with the powder in the vial. Gently swirl but do not shake the vial after mixing the medicine. Allow any bubbles or foam to settle before drawing the medicine into a syringe.
If the medicine has changed colors or has any particles in it, call your doctor for a new prescription.
Do not draw your interferon beta-1b dose into a syringe until you are ready to give yourself an injection. Use a different place on your skin each time you inject this medication. Do not inject interferon beta-1b into the same skin area two times in a row.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
To be sure this medication is not causing harmful effects, your blood and liver function will need to be tested on a regular basis. Your thyroid function may also need to be tested. Do not miss any scheduled visits to your doctor.
Store interferon beta-1b vials at room temperature away from moisture and heat. After mixing the medicine you should use it right away, or within 3 hours after mixing if you store it in a refrigerator. Do not freeze.
What happens if I miss a dose?
Use the medication as soon as you remember the missed dose. Then wait at least 48 hours before using another injection, and restart your dosing schedule at that time. Do not use more than one injection every 48 hours (2 days).
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an interferon beta-1b overdose are not known.
What should I avoid while using interferon beta-1b?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using interferon beta-1b.
Interferons can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.
Interferon beta-1b side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using interferon beta-1b and call your doctor at once if you have any of these serious side effects:
-
depressed mood, anxiety, trouble sleeping, restlessness, or thoughts of suicide or hurting yourself;
-
bruising, swelling, oozing, or skin changes where the injection was given;
-
weight changes, pounding heartbeats, feeling too hot or cold;
-
fever, chills, body aches, flu symptoms; or
-
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
-
weakness;
-
headache;
-
muscle pain or weakness;
-
sleep problems (insomnia);
-
stomach pain;
-
swelling in your hands or feet;
-
skin rash; or
-
irregular menstrual periods.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect interferon beta-1b?
There may be other drugs that can affect interferon beta-1b. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about interferon beta-1b.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with other, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 3.02. Revision Date: 09/08/2009 10:27:23 AM.
Extendryl
30/06/10
Generic Name: dexchlorpheniramine, methscopolamine, and phenylephrine (DEX klor fen IR a meen, METH skoe POL a meen, FEN il EFF rin)
Brand Names: DexPhen M, Extendryl, Re-Drylex
What is Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
Dexchlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Methscopolamine is an anticholinergic (an-tye-kol-in-URJ-ik) that has a drying effect on the nasal passages.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of dexchlorpheniramine, methscopolamine, and phenylephrine is used to treat runny nose, sneezing, itchy throat, watery eyes, and sinus congestion caused by allergies or the common cold.
This medication is also used to treat skin rash, hives, or swelling caused by an allergic reaction.
Dexchlorpheniramine, methscopolamine, and phenylephrine may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cold or allergy medicine before the MAO inhibitor has cleared from your body. You should not take this medication if you are allergic to dexchlorpheniramine, methscopolamine, or phenylephrine, or if you have glaucoma, heart disease, high blood pressure, or a thyroid disorder.
Before you take dexchlorpheniramine, methscopolamine, and phenylephrine, tell your doctor if you have a blockage in your stomach or intestines, kidney disease, diabetes, an enlarged prostate, problems with urination, or if you are over 40 years old.
Do not give this medication to a child younger than 6 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use any other over-the-counter cold or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains dexchlorpheniramine or phenylephrine.
What should I discuss with my health care provider before taking Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
Do not take this medication if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cold or allergy medicine before the MAO inhibitor has cleared from your body. You should not take this medication if you are allergic to dexchlorpheniramine, methscopolamine, or phenylephrine, or if you have:
-
glaucoma;
-
heart disease;
-
high blood pressure; or
-
a thyroid disorder.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take this medication, tell your doctor if you have:
-
a blockage in your stomach or intestines;
- kidney disease;
-
diabetes;
-
an enlarged prostate;
-
problems with urination; or
-
if you are over 40 years old;
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether dexchlorpheniramine, methscopolamine, and phenylephrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 6 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Older adults may be more likely to have side effects from this medicine.
How should I take Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cold medicine is usually taken for only a short time until your symptoms clear up.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Tell your doctor if your symptoms do not improve after a few days of treatment, or if you also have a fever with headache, cough, or skin rash.
This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.
Store this medicine at room temperature, away from heat, light, and moisture.
What happens if I miss a dose?
Since cold or allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include nausea, vomiting, extreme drowsiness, confusion, weak or shallow breathing, and seizure (convulsions).
What should I avoid while taking Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.
Do not use any other over-the-counter cold, cough, or allergy medication without first asking your doctor or pharmacist. Dexchlorpheniramine and phenylephrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains dexchlorpheniramine or phenylephrine. Avoid drinking alcohol. It can add to drowsiness caused by an antihistamine.
Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine) side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:
-
slow heart rate;
-
fast, pounding, or uneven heartbeats;
-
severe dizziness, anxiety, restless feeling, or nervousness;
-
painful or difficult urination;
-
urinating less than usual or not at all; or
-
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).
Less serious side effects may include:
-
blurred vision;
-
dizziness, drowsiness, feeling irritable;
-
restlessness or excitability (especially in children);
-
dry mouth, trouble swallowing;
-
nausea, constipation; or
-
warmth, tingling, or redness under your skin.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Extendryl (dexchlorpheniramine, methscopolamine, and phenylephrine)?
Tell your doctor about all other medications you use, especially:
-
guanethidine (Ismelin);
-
mecamylamine (Inversine);
-
methyldopa (Aldomet);
-
reserpine; or
-
a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), esmolol (Brevibloc), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;
This list is not complete and there may be other drugs that can interact with dexchlorpheniramine, methscopolamine, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about dexchlorpheniramine, methscopolamine, and phenylephrine.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 4/12/2009 4:46:18 PM.
Extendryl Chewable Tablets
30/06/10
Generic Name: Chlorpheniramine/Phenylephrine/Methscopolamine (KLOR-fen-IR-a-meen/FEN-il-EF-rin/METH-skoe-POL-a-meen)
Brand Name: Examples include AH-Chew and Extendryl
Extendryl Chewable Tablets are used for:
Relieving congestion, sneezing, runny nose, and itchy, watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Extendryl Chewable Tablets are an antihistamine, decongestant, and anticholinergic combination. It works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also relieves nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and dries the chest by decreasing lung secretions.
Do NOT use Extendryl Chewable Tablets if:
- you are allergic to any ingredient in Extendryl Chewable Tablets
- you are pregnant or breast-feeding
- you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
- you are taking or have taken medicine for high blood pressure or depression in the last 14 days
- you have a history of narrow-angle glaucoma, blockage in the stomach or intestines, peptic ulcer disease, intestinal or bowel problems, difficulty urinating, inflammation of the esophagus from reflux disease, difficulty swallowing, or uncontrolled bleeding
- you have severe heart disease or severe high blood pressure
Contact your doctor or health care provider right away if any of these apply to you.
Before using Extendryl Chewable Tablets:
Some medical conditions may interact with Extendryl Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, an enlarged prostate, a history of bladder or kidney problems, high blood pressure, diarrhea, asthma, nerve problems, heart problems, blood clots, a hiatal hernia, an adrenal gland tumor, glaucoma, breathing problems during sleep, myasthenia gravis (muscle weakness), or an overactive thyroid
Some MEDICINES MAY INTERACT with Extendryl Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Alpha-blockers (eg, guanethidine, methyldopa, prazosin), beta-blockers (eg, atenolol), diuretics (eg, furosemide, hydrochlorothiazide), furazolidone, or MAOIs (eg, phenelzine) because the risk of high or low blood pressure may be increased
- Alkalizers (eg, calcium or magnesium antacids), anticholinergics (eg, atropine, benztropine, dicyclomine), carbonic anhydrase inhibitors (eg, acetazolamide), ergotamine, sodium bicarbonate, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Extendryl Chewable Tablets’s side effects
- Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), certain stimulants (eg, doxapram, pseudoephedrine), cocaine, digoxin, droxidopa, potassium chloride, or sodium oxybate (GHB) because the risk of their side effects may be increased by Extendryl Chewable Tablets
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Extendryl Chewable Tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if Extendryl Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Extendryl Chewable Tablets:
Use Extendryl Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Extendryl Chewable Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Do not take Extendryl Chewable Tablets at the same time as antacids, certain medicines for diarrhea (eg, attapulgite, bismuth, kaolin, pectin), or ketoconazole. Take these medicines 2 or 3 hours before or after you take Extendryl Chewable Tablets.
- Chew thoroughly before swallowing. Follow with a glass of water.
- If you miss a dose of Extendryl Chewable Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Extendryl Chewable Tablets.
Important safety information:
- Extendryl Chewable Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Extendryl Chewable Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Extendryl Chewable Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- If your symptoms do not get better within 7 days or if they get worse or you develop a high fever or persistent headache, check with your doctor.
- Extendryl Chewable Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know that you are taking Extendryl Chewable Tablets.
- Extendryl Chewable Tablets may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
- Extendryl Chewable Tablets may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
- Extendryl Chewable Tablets may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- Do not take diet or appetite control medicines while you are taking Extendryl Chewable Tablets without checking with your doctor.
- If you have trouble sleeping, ask your doctor or pharmacist about the best time of day to take Extendryl Chewable Tablets.
- Diabetes patients – Extendryl Chewable Tablets may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Use Extendryl Chewable Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
- Extendryl Chewable Tablets should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use Extendryl Chewable Tablets if you are pregnant. If you think you may be pregnant, contact your doctor right away. Do not use Extendryl Chewable Tablets during labor or delivery because it could cause harm to the fetus. Extendryl Chewable Tablets are found in breast milk. Do not breast-feed while taking Extendryl Chewable Tablets.
Possible side effects of Extendryl Chewable Tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Blurred vision; clumsiness; constipation; dizziness; drowsiness; dry mouth, nose, or throat; excitability or irritability (especially in children); flushing; giddiness; headache; lack of energy; nausea; nervousness; tearing; trouble sleeping; unusual tiredness or weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; mental or mood changes; pounding in the chest; unusual bleeding or bruising; urinary retention; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include convulsions; deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing; vomiting.
Proper storage of Extendryl Chewable Tablets:
Store Extendryl Chewable Tablets in a tightly closed container between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Extendryl Chewable Tablets out of the reach of children and away from pets.
General information:
- If you have any questions about Extendryl Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.
- Extendryl Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Extendryl Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Extendryl Syrup
30/06/10
Generic Name: Chlorpheniramine/Phenylephrine/Methscopolamine (klor-fen-EER-a-meen/fen-ill-EF-rin/meth-skoe-POL-a-meen)
Brand Name: Examples include Dallergy and Extendryl
Extendryl Syrup is used for:
Relieving congestion, sneezing, runny nose, and itchy, watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Extendryl Syrup is an antihistamine, decongestant, and anticholinergic combination. It works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also relieves nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and dries the chest by decreasing lung secretions.
Do NOT use Extendryl Syrup if:
- you are allergic to any ingredient in Extendryl Syrup
- you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) in the last 14 days
- you have narrow-angle glaucoma; a blockage of the bladder, stomach, or intestines; peptic ulcer disease; severe bowel problems (eg, ulcerative colitis); inflammation of the esophagus from reflux disease; difficulty swallowing; myasthenia gravis (muscle weakness); or uncontrolled bleeding
- you have severe heart disease, severe high blood pressure, severe heart blood vessel problems, a rapid heartbeat, or you are unable to urinate
- you are having an asthma attack
Contact your doctor or health care provider right away if any of these apply to you.
Before using Extendryl Syrup:
Some medical conditions may interact with Extendryl Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of diabetes, an enlarged prostate, bladder or kidney problems, high blood pressure, asthma, lung problems (eg, emphysema), nerve problems, heart problems (eg, ischemic heart disease, irregular heartbeat), blood vessel problems, blood clots, stroke, a hiatal hernia, an adrenal gland tumor, increased pressure in the eye, glaucoma, or risk factors for glaucoma, breathing problems during sleep, seizures, trouble urinating, or an overactive thyroid
- if you have diarrhea
Some MEDICINES MAY INTERACT with Extendryl Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Sodium oxybate (GHB) because the risk of severe drowsiness or coma may be increased
- Furazolidone or MAOIs (eg, phenelzine) because severe high blood pressure, fast or irregular heartbeat, or seizures may occur
- Alpha-blockers (eg, prazosin), anesthetics (eg, chloroform, lidocaine), anticholinergics (eg, atropine, benztropine, dicyclomine), beta-blockers (eg, propranolol), carbonic anhydrase inhibitors (eg, acetazolamide), diuretics (eg, furosemide, hydrochlorothiazide), ergotamine, tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Extendryl Syrup’s side effects
- Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), certain stimulants (eg, doxapram, pseudoephedrine), cocaine, digoxin, droxidopa, or potassium chloride because the risk of their side effects may be increased by Extendryl Syrup
- Clonidine, guanethidine, guanfacine, mecamylamine, methyldopa, and reserpine because their effectiveness may be decreased by Extendryl Syrup
This may not be a complete list of all interactions that may occur. Ask your health care provider if Extendryl Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Extendryl Syrup:
Use Extendryl Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Extendryl Syrup by mouth with or without food.
- Do not take Extendryl Syrup at the same time as antacids, certain medicines for diarrhea (eg, kaolin, pectin, attapulgite, bismuth), or ketoconazole. Take these medicines 2 or 3 hours before or after you take Extendryl Syrup.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of Extendryl Syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Extendryl Syrup.
Important safety information:
- Extendryl Syrup may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Extendryl Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Extendryl Syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- If your symptoms do not get better within 7 days or if you develop a high fever or persistent headache, check with your doctor.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Extendryl Syrup may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
- Extendryl Syrup may make your eyes more sensitive to sunlight. It may help to wear sunglasses.
- Extendryl Syrup may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- Do not take diet or appetite control medicines while you are taking Extendryl Syrup without checking with your doctor.
- Extendryl Syrup has phenylephrine in it. Before you start any new medicine, check the label to see if it has phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Extendryl Syrup.
- Tell your doctor or dentist that you take Extendryl Syrup before you receive any medical or dental care, emergency care, or surgery.
- Diabetes patients – Extendryl Syrup may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Extendryl Syrup may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Extendryl Syrup.
- Use Extendryl Syrup with caution in the ELDERLY; they may be more sensitive to its effects.
- Extendryl Syrup should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if Extendryl Syrup can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Extendryl Syrup while you are pregnant. It is not known if Extendryl Syrup is found in breast milk. Do not breast-feed while taking Extendryl Syrup.
Possible side effects of Extendryl Syrup:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; dizziness; drowsiness; dry mouth, nose, or throat; excitability or irritability (especially in children); flushing; headache; nausea; nervousness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; clumsiness; difficulty swallowing; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; tremor; trouble sleeping; trouble urinating; unusual bleeding or bruising; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hallucinations; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing; vomiting.
Proper storage of Extendryl Syrup:
Store Extendryl Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Extendryl Syrup out of the reach of children and away from pets.
General information:
- If you have any questions about Extendryl Syrup, please talk with your doctor, pharmacist, or other health care provider.
- Extendryl Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Extendryl Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Exforge
30/06/10
Generic Name: amlodipine and valsartan (Oral route)
am-LOE-di-peen BES-i-late, val-SAR-tan
- Avoid Use in Pregnancy
- When pregnancy is detected, discontinue amlodipine besylate/valsartan as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus .
When pregnancy is detected, discontinue amlodipine besylate/valsartan as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus .
Commonly used brand name(s):
In the U.S.
- Exforge
Available Dosage Forms:
- Tablet
Therapeutic Class: Antihypertensive
Pharmacologic Class: Amlodipine
Chemical Class: Amlodipine
Uses For Exforge
Amlodipine and valsartan is a combination of medicines that are used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if high blood pressure is controlled.
Amlodipine is a calcium channel blocker. It affects the movement of calcium into the cells of the heart and blood vessels. As a result, amlodipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.
Valsartan is an angiotensin II receptor blocker. It works by blocking a substance in the body that causes blood vessels to tighten. As a result, valsartan relaxes blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
This medicine is available only with your doctor’s prescription.
Before Using Exforge
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of amlodipine and valsartan combination in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amlodipine and valsartan combination in the elderly. However, elderly patients may be more sensitive to the effects of this medicine than younger adults, which may require caution in patients receiving amlodipine and valsartan combination.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | D | Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. |
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Amiodarone
- Atazanavir
- Dantrolene
- Droperidol
- Fentanyl
- Lithium
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Aceclofenac
- Acemetacin
- Alclofenac
- Alprenolol
- Apazone
- Atenolol
- Benoxaprofen
- Betaxolol
- Bevantolol
- Bisoprolol
- Bromfenac
- Bucindolol
- Bufexamac
- Carprofen
- Carteolol
- Carvedilol
- Celecoxib
- Celiprolol
- Clometacin
- Clonixin
- Clopidogrel
- Conivaptan
- Dalfopristin
- Dexketoprofen
- Diclofenac
- Diflunisal
- Dilevalol
- Dipyrone
- Droxicam
- Esmolol
- Etodolac
- Etofenamate
- Felbinac
- Fenbufen
- Fenoprofen
- Fentiazac
- Floctafenine
- Fluconazole
- Flufenamic Acid
- Flurbiprofen
- Ibuprofen
- Indinavir
- Indomethacin
- Indoprofen
- Isoxicam
- Itraconazole
- Ketoconazole
- Ketoprofen
- Ketorolac
- Labetalol
- Levobunolol
- Lornoxicam
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Mepindolol
- Metipranolol
- Metoprolol
- Nabumetone
- Nadolol
- Naproxen
- Nebivolol
- Niflumic Acid
- Nimesulide
- Oxaprozin
- Oxprenolol
- Oxyphenbutazone
- Penbutolol
- Phenylbutazone
- Pindolol
- Pirazolac
- Piroxicam
- Pirprofen
- Propranolol
- Propyphenazone
- Proquazone
- Quinupristin
- Rifapentine
- Ritonavir
- Rofecoxib
- Saquinavir
- Sotalol
- St John’s Wort
- Sulindac
- Suprofen
- Talinolol
- Tenidap
- Tenoxicam
- Tertatolol
- Tiaprofenic Acid
- Timolol
- Tolmetin
- Valdecoxib
- Zomepirac
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Angina (severe chest pain) or
- Heart attack, acute—There is a small chance that this medicine may worsen these conditions.
- Dehydration or
- Diarrhea, severe or
- Heart attack, recent or
- Heart failure or other heart problems or
- Hyponatremia (low sodium in the blood) or
- Vomiting, severe—Use with caution. These conditions may cause the blood pressure to fall too low with this medicine.
- Kidney disease or
- Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Proper Use of Exforge
Amlodipine and valsartan combination is used when a single medicine to lower your blood pressure is not enough. It is also used as the first medicine to treat your condition if your doctor feels that you need to take more than one blood pressure medicine.
In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.
Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.
You may take this medicine with or without food.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- For high blood pressure:
- Adults—1 tablet once a day. Your doctor may increase your dose if needed.
- Children—Use and dose must be determined by your doctor.
- For high blood pressure:
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions While Using Exforge
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
Dizziness or lightheadedness may occur, especially if you have been taking a diuretic (water pill). Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you experience these effects.
You may also have dizziness, lightheadedness, or fainting if you exercise or if the weather is hot. Heavy sweating can cause loss of too much water and result in low blood pressure. Use extra care during exercise or hot weather.
Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
Exforge Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Bloating or swelling of face, arms, hands, lower legs, or feet
- rapid weight gain
- tingling of hands or feet
- unusual weight gain or loss
Less common
- Body aches or pain
- chills
- cough
- difficulty in breathing
- dizziness
- ear congestion
- fever
- headache
- loss of voice
- muscle aches
- sneezing
- sore throat
- stuffy or runny nose
- unusual tiredness or weakness
Rare
- Abnormal or decreased touch sensation
- ankle, knee, or great toe joint pain
- bladder pain
- bleeding after defecation
- bloody nose
- bloody or cloudy urine
- blurred or loss of vision
- burning feeling in chest or stomach
- burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
- burning, numbness, pain, or tingling in all fingers except smallest finger
- chest pain
- cold sweats
- confusion
- congestion
- cough producing mucus
- diarrhea
- difficult, burning, or painful urination
- disturbed color perception
- dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
- double vision
- dry mouth
- dryness of throat
- fast, irregular, pounding, or racing heartbeat or pulse
- flushed, dry skin
- frequent urge to urinate
- fruit-like breath odor
- general feeling of discomfort or illness
- halos around lights
- heart murmur
- hives
- hoarseness
- increased hunger
- increased thirst
- increased urination
- indigestion
- irritation
- itching
- joint pain, stiffness, or swelling
- labored breathing
- loss of appetite
- loss of consciousness
- lower back or side pain
- muscle pains
- nausea
- night blindness
- overbright appearance of lights
- pain in lower back, bottom, or hips
- pain in upper leg
- pain or tenderness around eyes and cheekbones
- rash
- redness of skin
- shivering
- shortness of breath or troubled breathing
- stomach cramps, tenderness, or pain
- stomachache
- sweating
- swelling of eyelids, face, lips, hands, or feet
- swelling with pits or depressions on skin
- swollen, painful, or tender lymph glands in neck, armpit, or groin
- tenderness in stomach area
- tightness of chest or wheezing
- tooth or gum pain
- trouble in swallowing
- trouble sleeping
- tunnel vision
- uncomfortable swelling around anus
- voice changes
- vomiting
- watery or bloody diarrhea
- weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Chest discomfort
- cold, clammy skin
- fast, weak pulse
- flushing
- lightheadedness or fainting
- slow heartbeat
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Rare
- Acid or sour stomach
- back pain
- belching
- bone pain
- continuing ringing or buzzing or other unexplained noise in ears
- decreased interest in sexual intercourse
- difficulty having a bowel movement (stool)
- difficulty in moving
- discouragement
- excess air or gas in stomach or intestines
- fear or nervousness
- feeling of constant movement of self or surroundings
- feeling sad or empty
- full or bloated feeling
- hearing loss
- heartburn
- inability to have or keep an erection
- increased sensitivity to sunlight
- irritability
- itching, pain, redness, or swelling of eye or eyelid
- lack or loss of strength
- loss in sexual ability, desire, drive, or performance
- loss of interest or pleasure
- muscle aching or cramping
- muscle spasms or stiffness
- pain in arms or legs
- passing gas
- pressure in the stomach
- redness in joints
- redness of skin
- sensation of spinning
- skin rash, encrusted, scaly and oozing
- sleepiness or unusual drowsiness
- sleeplessness
- stomach soreness, discomfort, or upset
- swelling of abdominal or stomach area
- tiredness
- toothache
- trouble concentrating
- unable to sleep
- unusually warm skin
- watering of eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.
Exforge HCT
30/06/10
Generic Name: amlodipine, hydrochlorothiazide, and valsartan (am LOE di peen, HYE droe klor oh THYE a zide, val SAR tan)
Brand Names: Exforge HCT
What is amlodipine, hydrochlorothiazide, and valsartan?
Amlodipine is in a group of drugs called calcium channel blockers. Amlodipine relaxes (widens) blood vessels and improves blood flow.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Valsartan is in a group of drugs called angiotensin II receptor antagonists. Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
The combination of amlodipine, hydrochlorothiazide, and valsartan is used to treat high blood pressure (hypertension).
This medication is usually given after other blood pressure medications have been tried without successful treatment of symptoms.
Amlodipine, hydrochlorothiazide, and valsartan may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about amlodipine, hydrochlorothiazide, and valsartan?
Your chest pain may become worse when you first start taking this medication or when your dose is increased. Call your doctor if your chest pain is severe or ongoing. You should not take this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic and others), valsartan (Diovan), or sulfa drugs, or if you are unable to urinate.
Before taking amlodipine, hydrochlorothiazide, and valsartan, tell your doctor if you have kidney or liver disease, congestive heart failure, asthma or allergies, low or high blood levels of potassium, gout, lupus, or diabetes.
Do not use this medication without telling your doctor if you are pregnant. Amlodipine, hydrochlorothiazide, and valsartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of amlodipine, hydrochlorothiazide, and valsartan. Do not use potassium supplements or salt substitutes while you are taking amlodipine, hydrochlorothiazide, and valsartan, unless your doctor has told you to.
What should I discuss with my healthcare provider before taking amlodipine, hydrochlorothiazide, and valsartan?
You should not take this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic and others), valsartan (Diovan), or sulfa drugs, or if you are unable to urinate.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take this medication:
- kidney disease;
- liver disease;
-
congestive heart failure;
-
asthma or allergies;
-
low or high levels of magnesium or potassium in your blood;
-
gout;
-
lupus; or
-
diabetes.
FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use this medication without telling your doctor if you are pregnant. Amlodipine, hydrochlorothiazide, and valsartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take amlodipine, hydrochlorothiazide, and valsartan?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take this medication with a full glass (8 ounces) of water. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance. Your chest pain may become worse when you first start taking this medication or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.
It may take up to 2 weeks of using this medicine before your blood pressure improves. For best results, keep using the medication as directed.
Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using this medication.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms, so you may not know when your blood pressure is high. You may need to use blood pressure medication for the rest of your life.
Store this medication at room temperature away from moisture and heat.
See also: Exforge HCT dosage in more detail
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include fast or slow heartbeat, confusion, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; feeling light-headed, and fainting.
What should I avoid while taking amlodipine, hydrochlorothiazide, and valsartan?
Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of amlodipine, hydrochlorothiazide, and valsartan. Do not use potassium supplements or salt substitutes while you are taking amlodipine, hydrochlorothiazide, and valsartan, unless your doctor has told you to.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Amlodipine, hydrochlorothiazide, and valsartan side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
-
feeling like you might pass out;
-
swelling, rapid weight gain;
-
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
-
slow, fast, or pounding heartbeats;
-
urinating less than usual, or not at all;
-
easy bruising or bleeding, unusual weakness;
-
numbness, burning, pain, or tingly feeling; or
-
jaundice (yellowing of the skin or eyes); or
-
dry mouth, increased thirst, drowsiness, restless feeling, confusion, increased urination, fast heart rate, fainting, or seizure (convulsions).
Less serious side effects may include:
-
dizziness;
-
headache, tired feeling;
-
nausea, upset stomach;
-
muscle spasms, back pain; or
-
stuffy nose, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect amlodipine, hydrochlorothiazide, and valsartan?
Tell your doctor about all other medications you use, especially:
-
any other blood pressure medications;
-
steroids (prednisone and others);
-
carbamazepine (Carbatrol, Tegretol);
-
lithium (Eskalith, Lithobid);
-
cholestyramine (Prevalite, Questran) or colestipol (Colestid);
-
insulin or diabetes medications you take by mouth;
-
a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
-
any other diuretics (water pills);
-
aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others;
-
a muscle relaxer such as baclofen (Lioresal), carisoprodol (Soma), cyclobenzaprine (Flexeril), dantrolene (Dantrium), metaxalone (Skelaxin), or methocarbamol (Robaxin), orphenadrine (Norflex), or tizanidine (Zanaflex);
-
a narcotic medication such as hydrocodone (Lortab, Vicodin), meperidine (Demerol), methadone (Methadose), morphine (Kadian, MS Contin), oxycodone (OxyContin), and others.
This list is not complete and there may be other drugs that can interact with amlodipine, hydrochlorothiazide, and valsartan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about amlodipine, hydrochlorothiazide, and valsartan.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.01. Revision Date: 07/20/2009 8:48:28 AM.
cnt FROM member_comment_new WHERE ddc_id = 3130 AND brand_name_id = 13790 AND r
Exgest LA
30/06/10
Generic Name: guaifenesin and phenylpropanolamine (gwye FEN e sin/fen ill proe pa NOLE a meen)
Brand Names: Ami-Tex LA, Banex-LA, Coldloc-LA, Dayquil Sinus Pressure and Congestion, Despec, Entex LA, Exgest LA, G-Vent, Guaifenex PPA 75, Guaivent, Guiatex LA, Naldecon-EX Pediatric, Nasahist LA, Phentex-LA, Phenylfenesin LA, Poly-Vent, Profen LA, Stamoist LA, Triaminic Expectorant, Vanex-LA
What is Exgest LA (guaifenesin and phenylpropanolamine)?
Guaifenesin is an expectorant. It is used to break up congestion and mucous to make breathing easier. Guaifenesin thins mucous, increases lubrication of the respiratory tract (lungs, nose and throat), and increases the removal of mucous.
Phenylpropanolamine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries), which reduces swelling of mucous membranes in areas such as the nose and sinuses.
Guaifenesin and phenylpropanolamine is used to treat the symptoms of the common cold and of infections of the sinuses, lungs, and throat.
Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.
Guaifenesin and phenylpropanolamine may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Exgest LA (guaifenesin and phenylpropanolamine)?
Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.
Drink plenty of extra fluids while taking this medication. Do not crush or chew the tablets. Swallow them whole or break them in half where they are scored to make them easier to swallow if needed.
Who should not take Exgest LA (guaifenesin and phenylpropanolamine)?
Do not take guaifenesin and phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Before taking this medication, tell your doctor if you have
-
high blood pressure or any other type of heart disease,
-
diabetes,
-
a peripheral vascular disorder (poor circulation),
-
glaucoma or increased pressure in the eyes,
-
an overactive thyroid, or
-
difficulty urinating or an enlarged prostate.
You may not be able to take guaifenesin and phenylpropanolamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Guaifenesin and phenylpropanolamine is in the FDA pregnancy category C. This means that it is not known whether guaifenesin and phenylpropanolamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. This medication passes into breast milk and may harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from guaifenesin and phenylpropanolamine. You may require a lower dose of this medication. Guaifenesin and phenylpropanolamine has not been approved for use by children younger than 6 years of age.
How should I take Exgest LA (guaifenesin and phenylpropanolamine)?
Take guaifenesin and phenylpropanolamine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water. Increasing fluid intake during the day may help relieve congestion. Take guaifenesin and phenylpropanolamine with food if it causes stomach upset. Do not crush or chew the tablets. Swallow them whole or break them in half where they are scored to make them easier to swallow if needed. Store guaifenesin and phenylpropanolamine at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a guaifenesin and phenylpropanolamine overdose include vomiting, high blood pressure (headache, redness of face, blurred vision), an irregular heartbeat, and numbness of the fingers or toes.
What should I avoid while taking Exgest LA (guaifenesin and phenylpropanolamine)?
Use caution when driving, operating machinery, or performing other hazardous activities. Guaifenesin and phenylpropanolamine may cause dizziness. If you experience dizziness, avoid these activities.
Exgest LA (guaifenesin and phenylpropanolamine) side effects
No serious side effects from guaifenesin and phenylpropanolamine are expected. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to take guaifenesin and phenylpropanolamine and talk to your doctor if you experience
-
dizziness or headache;
-
nervousness, restlessness, or insomnia;
-
nausea or stomach upset; or
-
difficulty urinating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect Exgest LA (guaifenesin and phenylpropanolamine)?
Do not take guaifenesin and phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Heart medications such as methyldopa (Aldomet), reserpine (Serpalan, Serpasil), and guanethidine (Ismelin) may have decreased effects. Talk to your doctor before taking guaifenesin and phenylpropanolamine if you are taking any of these medications.
Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking guaifenesin and phenylpropanolamine without first talking to your doctor or pharmacist. Other medications may also contain guaifenesin, phenylpropanolamine, or other similar drugs. You may accidentally take too much of these medicines.
Drugs other than those listed here may also interact with guaifenesin and phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
- Your pharmacist has additional information about guaifenesin and phenylpropanolamine written for health professionals that you may read.
What does my medication look like?
Guaifenesin and phenylpropanolamine is available with a prescription under several brand names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
-
Entex LA, 400 mg of guaifenesin and 75 mg of phenylpropanolamine–orange, scored tablets
-
Exgest LA, 400 mg of guaifenesin and 75 mg of phenylpropanolamine–white, oval-shaped, scored, long-acting tablets with blue speckles
-
Dura-Vent, 600 mg of guaifenesin and 75 mg of phenylpropanolamine–white, scored tablets
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 5.03. Revision Date: 2/13/04 4:04:29 PM.
