add to fAvorites

Drugs & Medications:A-Z

A
Advanced
B
C
Concise
D
Detailed
E
F
G
H
I
K
L
M
Med-facts
N
O
P
Professional
Q
R
S
T
U
Uncategorized
V
X
Z

Fluticasone/

Salmeterol Powder

Generic Name: Fluticasone/Salmeterol (floo-TIK-a-sone/sal-ME-ter-ol)
Brand Name: Advair Diskus

Long-acting beta-agonists such as salmeterol, an ingredient in Fluticasone/Salmeterol Powder, have been rarely associated with an increased risk of asthma-related death. Fluticasone/Salmeterol Powder should only be used by certain patients with severe asthma or by patients who cannot get adequate control of asthma symptoms by using other asthma-controller medicines (eg, inhaled corticosteroids).

Fluticasone/Salmeterol Powder is used for:

Long-term treatment of asthma and chronic obstructive pulmonary disease (COPD) in certain patients. It may also be used to treat other breathing conditions as determined by your doctor.

Fluticasone/Salmeterol Powder is a long-acting corticosteroid and bronchodilator combination. It works by reducing inflammation and widening the airways in the lungs, which helps you breath more easily.

Do NOT use Fluticasone/Salmeterol Powder if:

you are allergic to any ingredient in Fluticasone/Salmeterol Powder or to milk proteins
you are having an asthma attack (eg, sudden, severe onset or worsening of asthma symptoms such as chest tightness, cough, shortness of breath, wheezing)
you are using another type of long-acting inhaled bronchodilator (eg, formoterol inhalation powder, salmeterol inhalation powder)
you are taking an azole antifungal (eg, ketoconazole), certain HIV protease inhibitors (eg, ritonavir), a macrolide antibiotic (eg, clarithromycin), nefazodone, or telithromycin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone/Salmeterol Powder:

Some medical conditions may interact with Fluticasone/Salmeterol Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days
if you have high blood acid levels (eg, ketoacidosis) or a history of diabetes, glaucoma, or increased pressure in the eye, heart problems (eg, fast or irregular heartbeat, heart blood vessel problems), high blood pressure, nervous system problems, liver problems, low blood potassium levels, seizures, thyroid problems, or an adrenal gland tumor
if you are having a COPD flare-up, have recently been to an emergency room for asthma, have a history of frequent hospitalizations for asthma, or have ever had a life-threatening asthma attack
if you have a fungal, bacterial, or parasitic infection; a viral infection (eg, measles, chickenpox, shingles); herpes virus infection of the eye; tuberculosis (TB); a history of a positive TB skin test; or immune system problems; or if you have had a recent vaccination
if you have weak bones (osteoporosis) or have risk factors for osteoporosis (eg, a family history of osteoporosis, tobacco use, long-term use of corticosteroids or certain seizure medicines, limited physical exercise, poor nutrition)

Some MEDICINES MAY INTERACT with Fluticasone/Salmeterol Powder. Tell your health care provider if you are taking any other medicines, especially any of the following:

Diuretics (eg, hydrochlorothiazide, furosemide) or long-acting inhaled bronchodilators (eg, salmeterol inhalation powder, formoterol inhalation powder) because the risk of low blood potassium or irregular heartbeat may be increased
Beta-blockers (eg, propranolol) because they may decrease Fluticasone/Salmeterol Powder’s effectiveness
Azole antifungals (eg, ketoconazole), catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), delavirdine, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin), MAOIs (eg, phenelzine), nefazodone, short-acting beta-agonist bronchodilators (eg, albuterol), telithromycin, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Fluticasone/Salmeterol Powder’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone/Salmeterol Powder may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone/Salmeterol Powder:

Use Fluticasone/Salmeterol Powder as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Fluticasone/Salmeterol Powder comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Fluticasone/Salmeterol Powder refilled.
Do not use a spacer with Fluticasone/Salmeterol Powder.
Always ready and use this device in a level, flat position.
Hold the device in one hand and put the thumb of your other hand on the thumb grip. Push your thumb away from you as far as it will go until the mouthpiece appears and snaps into position.
Hold the device in a level, flat position with the mouthpiece toward you. Slide the lever away from you as far as it will go until it clicks.
Do NOT close or tilt the device, play with the lever, or move the lever more than 1 time. This may release or waste extra doses.
Hold the device away from your mouth and breathe out fully. Do NOT breathe into the inhaler. Put the mouthpiece to your lips. Breathe in quickly and deeply through the device.
Remove the device from your mouth. Hold your breath for about 10 seconds, or as long as is comfortable. Then breathe out slowly.
Close the device. Put your thumb on the thumb grip and slide it back toward you as far as it will go. The device will click shut and the lever will return to its original position.
Your dose of medicine is a very fine powder. Most, but not all, patients can taste or feel the dose. Do NOT use another dose if you do not taste or feel the medicine. If you are not sure if you are receiving your dose, contact your doctor or pharmacist.
Rinse your mouth with water after using Fluticasone/Salmeterol Powder. DO NOT swallow the rinse solution. Spit the rinse water out.
If you are using other inhaled medicines, wait a few minutes between using Fluticasone/Salmeterol Powder and other inhalers, unless directed otherwise by your doctor.
Take your doses of Fluticasone/Salmeterol Powder about 12 hours apart, unless your doctor tells you otherwise.
Never wash the mouthpiece or any other part of the inhaler. Keep it dry. Store Fluticasone/Salmeterol Powder in a dry place.
Throw Fluticasone/Salmeterol Powder away 1 month after you remove it from the foil pouch, or after the dose indicator reads “0,” whichever comes first.
You may breathe more easily after the first dose of Fluticasone/Salmeterol Powder. However, it may take 1 week or longer to achieve the most benefit.
Use Fluticasone/Salmeterol Powder on a regular schedule to get the most benefit from it. Using Fluticasone/Salmeterol Powder at the same times each day will help you remember to use it. Do not stop using Fluticasone/Salmeterol Powder even if you feel better unless your doctor tells you to.
If you miss a dose of Fluticasone/Salmeterol Powder, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone/Salmeterol Powder.

Important safety information:

Fluticasone/Salmeterol Powder may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Fluticasone/Salmeterol Powder with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Fluticasone/Salmeterol Powder will not stop an asthma attack once one has started. Be sure to carry a short-acting bronchodilator with you at all times to treat any breathing problems that may occur between doses of Fluticasone/Salmeterol Powder (eg, severe or sudden onset of wheezing or shortness of breath). If you have any questions about which medicines stop asthma attacks, check with your doctor or pharmacist.
If you have been regularly using a short-acting bronchodilator inhaler (eg, albuterol), talk with your doctor about how to use it with Fluticasone/Salmeterol Powder. Short-acting bronchodilators are normally only used with Fluticasone/Salmeterol Powder to treat breathing problems that may occur between doses.
Talk with your doctor or pharmacist about all of your asthma medicines and how to use them. Do not start, stop, or change the dose of any asthma medicine unless your doctor tells you to.
If your symptoms do not get better within 1 week or if they get worse after you start using Fluticasone/Salmeterol Powder, check with your doctor.
Tell your doctor or dentist that you take Fluticasone/Salmeterol Powder before you receive any medical or dental care, emergency care, or surgery.
Tell your doctor at once if you notice your short-acting bronchodilator inhaler does not work as well, if you need to use it more often (eg, more than 4 times a day for more than 2 days in a row, or 1 whole canister within 8 weeks’ time), or if you have a decrease in your peak meter flow results.
The risk of serious heart problems (eg, irregular heartbeat) may be greater if you use Fluticasone/Salmeterol Powder in high doses. Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor.
Fluticasone/Salmeterol Powder may sometimes causes severe breathing problems right after you use a dose. If this happens, use your short-acting bronchodilator inhaler. Seek medical care at once if your breathing does not improve after you use the short-acting bronchodilator. Tell your doctor about this reaction.
Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone/Salmeterol Powder. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, a sudden asthma attack, or severe fluid or electrolyte loss. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does. Contact your doctor at once if you have contact with anyone who has these infection.
Check with your doctor before you receive any vaccine while you are using Fluticasone/Salmeterol Powder.
Diabetes patients – Fluticasone/Salmeterol Powder may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Lab tests, including lung function tests and eye exams, may be performed while you use Fluticasone/Salmeterol Powder. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Fluticasone/Salmeterol Powder with caution in the ELDERLY; they may be more sensitive to its effects, especially pneumonia, decreased bone density, and effects on the heart.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone/Salmeterol Powder.
Fluticasone/Salmeterol Powder should not be used in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone/Salmeterol Powder while you are pregnant. It is not known if Fluticasone/Salmeterol Powder is found in breast milk. If you are or will be breast-feeding while you use Fluticasone/Salmeterol Powder, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fluticasone/Salmeterol Powder:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; mild muscle or bone pain; nausea; nervousness; throat irritation; tremor; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes; blurred vision or other vision changes; chest pain; choking; fast or irregular heartbeat; hoarseness; numbness or tingling in hands or feet; seizures; severe muscle weakness, cramps, or spasms; severe or persistent bone pain; severe or persistent dizziness or headache; signs of infection (eg, fever, chills, persistent headache/sore throat, ear pain, increased mucus production or change in mucus color); swelling or tightness in the throat; trouble sleeping; unusual tiredness or weakness; vaginal odor or discharge; weight gain; white patches or sores on the tongue or mouth; worsening of asthma symptoms (eg, increased wheezing, coughing, chest tightness, shortness of breath).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest pain; fainting; muscle cramping; seizures; severe muscle weakness; severe or persistent dizziness, headache, or trouble sleeping; unusually fast or irregular heartbeat.

Proper storage of Fluticasone/Salmeterol Powder:

Store Fluticasone/Salmeterol Powder between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fluticasone/Salmeterol Powder out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone/Salmeterol Powder, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone/Salmeterol Powder is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone/Salmeterol Powder. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

fluticasone and salmeterol

30/06/10

Generic Name: fluticasone and salmeterol (inhalation) (floo TIK a sone, sal ME te rol)
Brand Names: Advair Diskus, Advair HFA

What is fluticasone and salmeterol inhalation?

Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Salmeterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Fluticasone and salmeterol inhalation is used to prevent asthma attacks. It is also used to prevent flare-ups or worsening of chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis and/or emphysema.

Fluticasone and salmeterol may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about fluticasone and salmeterol?

Do not use fluticasone and salmeterol to treat an asthma attack that has already begun. Salmeterol may increase the risk of asthma-related death. Use only the prescribed dose of fluticasone and salmeterol, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using this medication.

Before using fluticasone and salmeterol, tell your doctor if you have a food or drug allergy, heart disease, high blood pressure, a seizure disorder, an infection, a weak immune system, diabetes, glaucoma, tuberculosis, osteoporosis, a thyroid disorder, or liver disease.

Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack. If you use a peak flow meter at home, call your doctor if your numbers are lower than normal.

What should I discuss with my healthcare provider before using this medication?

Do not use this medication if you are allergic to fluticasone (Flonase, Flovent), salmeterol (Serevent), or milk proteins, or if you are having an asthma attack or severe COPD symptoms.

If you have any of these other conditions, you may need a dose adjustment or special tests:

a food or drug allergy;
heart disease or high blood pressure;
epilepsy or other seizure disorder;
an infection of any kind;
a weak immune system;
diabetes;
glaucoma;
tuberculosis;
osteoporosis;
a thyroid disorder; or
liver disease.

FDA pregnancy category C. It is not known whether fluticasone and salmeterol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether fluticasone and salmeterol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Fluticasone and salmeterol inhalation can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Do not give this medication to a child younger than 4 years old.

Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.

How should I use this medication?

Salmeterol may increase the risk of asthma-related death. Use only the prescribed dose of fluticasone and salmeterol, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using this medication. Do not use fluticasone and salmeterol inhalation to treat an asthma attack that has already begun. It will not work fast enough. Use only a fast-acting inhalation medication.

Advair Diskus is a powder form of fluticasone and salmeterol that comes with a special inhaler device pre-loaded with blister packs containing measured doses of the medicine. The device opens and loads a blister each time you use the inhaler. This device is not to be used with a spacer.

Advair HFA is an aerosol form of fluticasone and salmeterol that comes in a canister that is used with an actuator inhaler device. Use only the inhaler device provided with Advair HFA. This device is not to be used with a spacer.

Shake the Advair HFA inhaler for at least 5 seconds before each spray.

Keep track of the number of sprays you have used and throw away the Advair HFA canister after 120 sprays, even if it feels like there is still medicine in it.

If you also use a steroid medication, do not stop using the steroid suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about using less and less of the steroid before stopping completely.

Carry an identification card or wear a medical alert ID to let others know that you may need an oral steroid in an emergency. Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack. If you use a peak flow meter at home, call your doctor if your numbers are lower than normal.

Use all of your medications as directed by your doctor. Talk with your doctor if your medications do not seem to work as well in treating or preventing attacks. Do not change your doses or medication schedule without advice from your doctor.

Store at room temperature away from moisture and heat. Keep the Advair HFA canister away from high heat, such as open flame or in a car on a hot day. The canister may explode if it gets too hot.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include angina or chest pain, fast or irregular heartbeats, seizures, tremor, weakness, headache, nausea, and vomiting.

What should I avoid while using this medication?

Do not use a second form of salmeterol (such as Serevent) or use a similar inhaled bronchodilator such as formoterol (Foradil) unless your doctor has told you to.

Fluticasone and salmeterol can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medicines.

This medication side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

bronchospasm (wheezing, chest tightness, trouble breathing);
fast or uneven heart beats, restless feeling, tremor;
fever, chills, stabbing chest pain, cough with yellow or green mucus;
blurred vision, eye pain, or seeing halos around lights;
white patches or sores inside your mouth or on your lips; or
worsening asthma symptoms.

Less serious side effects include:

headache, dizziness;
nausea, vomiting, diarrhea;
dry mouth, nose, or throat;
stuffy nose, sinus pain, cough, sore throat; or
hoarseness or deepened voice.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Fluticasone and salmeterol Dosing Information

Usual Adult Dose for Chronic Obstructive Pulmonary Disease — Maintenance:

For the maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease with chronic bronchitis and/or emphysema and to reduce exacerbations of COPD in patients with a history of exacerbations:

Inhalation powder and chlorofluorocarbon (CFC) inhalation aerosol:
1 inhalation (250 mcg-50 mcg) twice a day (morning and evening, approximately 12 hours apart). This is the only approved dosage for the treatment of COPD associated with chronic bronchitis. Higher doses are not recommended, as no additional improvement in lung function was observed and higher doses of corticosteroids increase the risk of systemic effects. Treatment for longer than 6 months has not been evaluated.

Usual Adult Dose for Asthma — Maintenance:

Inhalation powder:
For patients not currently on an inhaled corticosteroid, including patients on non-corticosteroid maintenance therapy:
1 inhalation (100 mcg-50 mcg) twice a day.

For patients currently on another inhaled corticosteroid, the dose of fluticasone-salmeterol is based on the dose used for the other inhaled corticosteroid:
Range: 1 inhalation (100 mcg-50 mcg) twice a day to a maximum of 1 inhalation (500 mcg-50 mcg) twice a day. The maximum recommended dose is 500 mcg-50 mcg twice a day. More than one inhalation twice a day is not recommended.

Inhalation aerosol:
For patients not currently on an inhaled corticosteroid, including patients on non-corticosteroid maintenance therapy:
2 inhalations of 45 mcg-21 mcg twice a day or 2 inhalations of 115 mcg-21 mcg twice a day.
The maximum recommended dosage is 2 inhalations of 230 mcg-21 mcg twice a day.

For patients currently on another inhaled corticosteroid, the dose of fluticasone-salmeterol is based on the dose used for the other inhaled corticosteroid:
Range: 2 inhalations of 45 mcg-21 mcg twice a day to a maximum of 2 inhalation of 230 of mcg-21 mcg twice a day. The maximum recommended dose is 2 inhalations of 230 mcg-21 mcg twice a day. More than 2 inhalations twice a day is not recommended.

Usual Pediatric Dose for Asthma — Maintenance:

4 years to 11 years:
Inhalation powder:
For patients who are symptomatic on an inhaled corticosteroid:
1 inhalation (100 mcg-50 mcg) twice a day.

> 12 years:
Inhalation powder:
For patients not currently on an inhaled corticosteroid, including patients on non-corticosteroid maintenance therapy:
1 inhalation (100 mcg-50 mcg) twice a day.

For patients currently on another inhaled corticosteroid, the dose of fluticasone-salmeterol is based on the dose used for the other inhaled corticosteroid:
Range: 2 inhalation of 45 mcg-21 mcg twice a day to a maximum of 2 inhalation of 230 of mcg-21 mcg twice a day. The maximum recommended dose is two inhalations of 230 mcg-21 mcg twice a day. More than two inhalations twice a day is not recommended.

What other drugs will affect this medication?

Before using fluticasone and salmeterol inhalation, tell your doctor if you are using any of the following drugs:

amiodarone (Cordarone);
a diuretic or “water pill”;
HIV medicines such as atazanavir (Reyataz), ritonavir (Norvir), indinavir (Crixivan), nelfinavir (Viracept), or saquinavir (Invirase);
an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam);
an antidepressant such as amitriptyline (Elavil), desipramine (Norpramin), fluoxetine (Prozac), nefazodone, or imipramine (Tofranil);
antibiotics such as clarithromycin (Biaxin) or telithromycin (Ketek);
antifungal medications such as ketoconazole (Nizoral) or itraconazole (Sporanox); or
a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), and others.

This list is not complete and other drugs may interact with fluticasone and salmeterol inhalation. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about fluticasone and salmeterol inhalation.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,F

Comments (0)

fluticasone and salmeterol (Inhalation route)

30/06/10

floo-TIK-a-sone PROE-pee-oh-nate, sal-ME-ter-ol zye-NAF-oh-ate

Inhalation, oral/nebulization routeDisk

Long-acting beta 2-adrenergic agonists, such as salmeterol, one of the active ingredients in the fluticasone propionate/salmeterol inhalation powder, may increase the risk of asthma-related death. Therefore, when treating patients with asthma, physicians should only prescribe fluticasone propionate/salmeterol for patients not adequately controlled on other asthma-controller medications (e.g., low- to medium-dose inhaled corticosteroids) or whose disease severity clearly warrants initiation of treatment with 2 maintenance therapies. Data from a large placebo-controlled US study that compared the safety of salmeterol inhalation aerosol or placebo added to usual asthma therapy showed an increase in asthma-related deaths in patients receiving salmeterol (13 deaths out of 13,176 patients treated for 28 weeks on salmeterol versus 3 deaths out of 13,179 patients on placebo) .

Long-acting beta 2-adrenergic agonists may increase the risk of asthma-related deaths. Therefore, when treating patients with asthma, fluticasone propionate/salmeterol inhalation powder should only be used for patients not adequately controlled on other asthma-controller medications or whose disease severity clearly warrants initiation of treatment with 2 maintenance therapies .

Commonly used brand name(s):

In the U.S.

Advair Diskus
Advair Diskus 100/50
Advair Diskus 250/50
Advair Diskus 500/50
Advair HFA

In Canada

Advair
Advair Inhalation Aerosol

Available Dosage Forms:

Aerosol Liquid
Disk
Aerosol Powder

Therapeutic Class: Antiasthma, Anti-Inflammatory/Bronchodilator Combination

Pharmacologic Class: Fluticasone

Uses For fluticasone and salmeterol

Fluticasone and salmeterol is a combination of two medicines that are used to help control the symptoms of asthma and improve breathing. It is used when a patient’s asthma has not been controlled sufficiently on other asthma medicines, or when a patient’s condition is so severe that more than one medicine is needed every day. fluticasone and salmeterol will not relieve an asthma attack that has already started.

fluticasone and salmeterol is also used to treat air flow blockage and reduce the worsening of chronic obstructive pulmonary disease (COPD). This includes chronic bronchitis and emphysema.

Inhaled fluticasone belongs to the family of medicines known as corticosteroids or steroids (cortisone-like medicines). It works by preventing certain cells in the lungs and breathing passages from releasing substances that cause asthma symptoms.

Inhaled salmeterol is a long-acting bronchodilator. Bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs. Salmeterol does not act quickly enough to relieve an asthma attack that has already started.

fluticasone and salmeterol must be used with a short-acting medicine (e.g. albuterol) for an asthma attack or asthma symptoms that need attention right away.

fluticasone and salmeterol is available only with your doctor’s prescription.

Before Using fluticasone and salmeterol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fluticasone and salmeterol, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fluticasone and salmeterol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluticasone and salmeterol combination in children older than 4 years of age. Safety and efficacy have not been established for children younger than 4 years old.

Appropriate studies have not been performed on the relationship of age to the effects of Advair® HFA oral inhalation in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluticasone and salmeterol combination in the elderly. However, elderly people with heart and blood vessel problems may require special caution when receiving fluticasone and salmeterol combination.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using fluticasone and salmeterol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acebutolol
Alprenolol
Arotinolol
Atazanavir
Atenolol
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Bupropion
Carteolol
Carvedilol
Celiprolol
Clarithromycin
Clorgyline
Darunavir
Dilevalol
Esmolol
Furazolidone
Indinavir
Iproniazid
Isocarboxazid
Itraconazole
Ketoconazole
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nefazodone
Nelfinavir
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Ritonavir
Saquinavir
Selegiline
Sotalol
Talinolol
Telithromycin
Tertatolol
Timolol
Tipranavir
Toloxatone
Tranylcypromine

Using fluticasone and salmeterol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Erythromycin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of fluticasone and salmeterol

Inhaled fluticasone and salmeterol is used to prevent asthma attacks and to treat chronic obstructive pulmonary disease (COPD). It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor.

Inhaled fluticasone and salmeterol is used with a special inhaler that comes with patient directions or a medication guide. Read the directions carefully before using fluticasone and salmeterol. If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.

Use fluticasone and salmeterol only as directed. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop taking fluticasone and salmeterol without telling your doctor. To do so may increase the chance of side effects.

In order for fluticasone and salmeterol to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.

Do not stop using fluticasone and salmeterol or other asthma medicines that your doctor has prescribed for you unless you have discussed this with your doctor.

When you use the inhaler for the first time, or if you have not used it for 7 days or longer, or if the inhaler has been dropped, it may not deliver the right amount of medicine with the first puff. Therefore, before using the inhaler, prime it by spraying the medicine four times into the air away from the face, and shaking it well for 5 seconds before each spray. Avoid spraying it in your eyes.

Rinsing your mouth with water after each dose may help prevent hoarseness, throat irritation, and infection in the mouth. However, do not swallow the water after rinsing.

To use the inhaler:

To open the inhaler, push the thumb grip away from you as far as it will go. You will hear a click and feel a snap. When open, the mouthpiece will appear.
Slide the mouthpiece lever away from you as far as it will go until it clicks. The inhaler is now ready to use. If you close the inhaler or push the lever again, you will lose medicine.
Turn your head away from the inhaler, and breathe out to the end of a normal breath. Do not breathe into the inhaler.
Holding the inhaler level, put the mouthpiece between your lips and teeth, and close your lips around the mouthpiece. Do not bite down on the mouthpiece. Do not block the mouthpiece with your teeth or tongue.
Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not breathe through your nose.
Hold your breath and remove the mouthpiece from your mouth. Continue holding your breath as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.
Turn your head away from the inhaler, and breathe out slowly to the end of a normal breath. Do not breathe into the inhaler.
If your doctor has told you to inhale more than one puff of medicine at each dose, take the second puff following exactly the same steps you used for the first puff.
When you are finished, close the inhaler. Place your thumb on the thumb grip, and slide it back toward you as far as it will go. You will hear it click shut.
Keep the inhaler dry. Do not wash the mouthpiece, or any other part of the inhaler. You may use a dry cloth to wipe it clean.
The inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The doses counting down from 20 to 0 will show up in red to remind you to refill your prescription. Throw away the inhaler when the count is 000. You may not receive the right amount of medicine.

Dosing

The dose of fluticasone and salmeterol will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of fluticasone and salmeterol. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation dosage form (aerosol):
- For preventing an asthma attack:
  - Adults and children 12 years of age and older—Two puffs in the morning and another two puffs in the evening.
  - Children younger than 12 years of age—Use and dose must be determined by your child’s doctor.

For inhalation dosage form (powder):
- For bronchial asthma:
  - Adults and children 4 years of age and older—One inhalation two times a day, about 12 hours apart.
  - Children up to 4 years of age—Use and dose must be determined by your doctor.
- For chronic obstructive pulmonary disease (COPD) with chronic bronchitis or emphysema:
  - Adults—One inhalation (250/50) two times a day, about 12 hours apart.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of fluticasone and salmeterol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep fluticasone and salmeterol inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using fluticasone and salmeterol

It is very important that your doctor check your or your child’s progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects caused by fluticasone and salmeterol.

You should not use fluticasone and salmeterol if your asthma attack has already started. Your doctor will prescribe another medicine (e.g., a short-acting inhaler) for you to use in case of an acute asthma attack. Make sure you understand how to use the short-acting inhaler. Talk to your doctor if you need instructions.

Talk with your doctor or get medical care right away if:

Your symptoms do not improve after using fluticasone and salmeterol for 1 week or if they become worse.
Your short-acting inhaler does not seem to work as well as it used to and you need it more often than normal.
You have a big decrease in your peak flow when measured as directed by your doctor.

Do not use fluticasone and salmeterol to treat wheezing that is getting worse. Call your doctor right away if wheezing worsens while using fluticasone and salmeterol.

Do not use any other asthma medicine or medicine for breathing problems without talking to your doctor. fluticasone and salmeterol should not be used with other inhalers that contain budesonide and formoterol combination (Symbicort®), formoterol (Foradil® Aerolizer®, Perforomist™), or arformoterol (Brovona™).

Although fluticasone and salmeterol decreases the number of asthma episodes, these medicines may increase the chances of a severe asthma attack when they do occur. Be sure to read about these risks in the medication guide and talk to your doctor or pharmacist about any questions or concerns that you have.

Patients with COPD may be more likely to have pneumonia. Call your doctor if you start having increased sputum (spit) production, change in sputum color, fever, chills, increased cough, or an increase in breathing problems.

Do not change your dose or stop using your medicine without asking your doctor first.

Your doctor may want you to carry a medical identification (ID) card stating that you are using fluticasone and salmeterol. The card will say that you may need additional medicine during an emergency, a severe asthma attack or other illness, or unusual stress.

fluticasone and salmeterol may cause bronchospasm, which may be life-threatening. Check with your doctor right away if you are having a cough, difficulty with breathing, shortness of breath, or wheezing.

If you develop a skin rash, hives, or any allergic reaction to fluticasone and salmeterol, stop taking the medicine and check with your doctor as soon as possible.

Check with your doctor right away if you have chest pain, a fast heartbeat, nervousness, shaking of the hands or feet, noisy breathing, a feeling of choking, or tightness or irritation of the throat while using fluticasone and salmeterol.

Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

fluticasone and salmeterol may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.

fluticasone and salmeterol may cause children to grow more slowly than usual. Talk to your child’s doctor if you have any concerns.

fluticasone and salmeterol may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

fluticasone and salmeterol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools
blindness
blurred vision
burning, tingling, numbness, or pain in the hands, arms, feet, or legs
chills
cough
decreased vision
difficulty with breathing or swallowing
eye pain
fast heartbeat
fever
headache
hives or welts
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
nausea or vomiting
noisy breathing
painful or difficult urination
sensation of pins and needles
shortness of breath
skin itching, rash, or redness
sore throat
sores, ulcers, or white spots on the lips or in the mouth
stabbing pain in the arms or legs
swelling of the face, throat, or tongue
swollen glands
tearing
unusual bleeding or bruising
wheezing

Incidence not known

Abdominal or stomach pain
backache
bruising
darkening of the skin
decrease in height
diarrhea
difficulty with moving
dizziness
facial hair growth in females
fainting
fast, slow, pounding, or irregular heartbeat or pulse
flushed, dry skin
fractures
fruit-like breath odor
full or round face, neck, or trunk
heavy bleeding
increased hunger
increased thirst or urination
irritability
large, flat, blue, or purplish patches in the skin
loss of sexual desire or ability
menstrual irregularities
mental depression
muscle pain or stiffness
muscle wasting
pain in the back, ribs, arms, or legs
pain in the joints
sweating
troubled breathing
unexplained weight loss
unusual tiredness or weakness
weight gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Chest pain or tightness
confusion
convulsions (seizures)
decreased urine output
dry mouth
faintness, or lightheadedness when getting up from a lying or sitting position suddenly
general feeling of discomfort or illness
high blood pressure
loss of appetite
mood changes
nervousness
numbness or tingling in the hands, feet, or lips
sudden sweating
tremors
trouble with sleeping

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain
choking
congestion
dryness of the throat
high-pitched noise when breathing
hoarseness
runny nose
sneezing
trouble with swallowing
voice changes

Less common

Cough-producing mucus
flu-like symptoms
irritation or inflammation of the eye
muscle pain
pain or tenderness around the eyes and cheekbones
sleep disorders
stuffy nose
white patches in the mouth or throat or on the tongue

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Advanced,F

Comments (0)

fluticasone furoate (Nasal route)

30/06/10

floo-TIK-a-sone FURE-oh-ate

Commonly used brand name(s):

In the U.S.

Veramyst

Available Dosage Forms:

Spray

Therapeutic Class: Corticosteroid, Strong

Pharmacologic Class: Fluticasone

Uses For fluticasone furoate

Fluticasone furoate is used to treat sneezing, itchy or runny nose, or other symptoms caused by hay fever. fluticasone furoate is a corticosteroid.

fluticasone furoate is available only with your doctor’s prescription.

Before Using fluticasone furoate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fluticasone furoate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fluticasone furoate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluticasone furoate in children. Safety and efficacy have not been established in children younger than 2 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fluticasone furoate in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving fluticasone furoate.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using fluticasone furoate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Atazanavir
Bupropion
Clarithromycin
Darunavir
Indinavir
Itraconazole
Ketoconazole
Nefazodone
Nelfinavir
Ritonavir
Saquinavir
Telithromycin
Tipranavir

Interactions with Food/Tobacco/Alcohol

Proper Use of fluticasone furoate

fluticasone furoate comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

fluticasone furoate is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

If you are using the nasal spray for the first time, you will need to prime the spray. To do this, you should release six test sprays into the air away from the face, or pump the bottle until some of the medicine sprays out. Now it is ready to use. Prime the spray if it has not been used for more than 30 days or if the cap has been left off the bottle for 5 days or longer. Shake the medicine well before each use.

Before using the medicine, gently blow your nose to clear the nostrils.

After using the nasal spray, wipe the tip of the bottle with a clean tissue and put the cap back on.

You may need to use fluticasone furoate for a few days before you start to feel better.

Dosing

The dose of fluticasone furoate will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of fluticasone furoate. If your dose is different, do not change it unless your doctor tells you to do so.

For nasal dosage form (spray):
- For symptoms of hay fever:
  - Adults and children 12 years of age and older—110 micrograms (mcg) or 2 sprays in each nostril once a day. Your doctor may decrease your dose to 55 mcg or 1 spray in each nostril once a day.
  - Children 2 to 11 years of age—55 mcg or 1 spray in each nostril once a day. Your child’s doctor may need to increase the dose up to 2 sprays in each nostril once a day depending on your child’s condition.
  - Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of fluticasone furoate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using fluticasone furoate

It is very important that your doctor check you at regular visits for any problems or unwanted effects that may be caused by fluticasone furoate.

You may get infections more easily while using fluticasone furoate. Tell your doctor right away if you have been exposed to someone with chickenpox or measles. Also tell your doctor if you develop white patches or sores in your nose while you are using fluticasone furoate. This could be symptoms of a candida or yeast infection.

fluticasone furoate may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using fluticasone furoate.

fluticasone furoate may slow down a child’s growth. If you think your child is not growing properly while using fluticasone furoate, talk with your doctor.

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

fluticasone furoate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloody nose

Less common

Cough
fever
headache
muscle aches
sore throat
sores inside nose
stuffy or runny nose
unusual tiredness or weakness

Incidence not known

Difficulty with swallowing
dizziness
fast heartbeat
hives or welts
itching
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the skin
shortness of breath
skin rash
tightness in the chest
wheezing

Less common

Back pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,F

Comments (0)

Fluticasone Furoate Spray

30/06/10

Generic Name: Fluticasone Furoate (floo-TIK-a-sone)
Brand Name: Veramyst

Fluticasone Furoate Spray is used for:

Treatment of allergic and nonallergic nasal symptoms including congestion, sneezing, itching, and runny nose.

Fluticasone Furoate Spray is a corticosteroid. It works by reducing inflammatory reactions in the nasal airway in response to allergens and irritants in the air.

Do NOT use Fluticasone Furoate Spray if:

you are allergic to any ingredient in Fluticasone Furoate Spray
you have recently had an ulcer in your nose, nasal surgery, or a nasal injury
you are taking certain HIV protease inhibitors (eg, ritonavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone Furoate Spray:

Some medical conditions may interact with Fluticasone Furoate Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have active or inactive tuberculosis or a positive skin test for tuberculosis
if you have infections of the respiratory tract, untreated fungal or bacterial infections, parasitic or viral infections, measles, chickenpox, or herpes simplex in or around the eye, or you have recently received a vaccination
if you have diarrhea or a history of severe liver problems, asthma, glaucoma, or cataracts
if you have a medical condition requiring long-term use of corticosteroids (eg, prednisone)

Some MEDICINES MAY INTERACT with Fluticasone Furoate Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

Azole antifungals (eg, ketoconazole), certain HIV protease inhibitors (eg, ritonavir), or delavirdine because they may increase the risk of Fluticasone Furoate Spray’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone Furoate Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone Furoate Spray:

Use Fluticasone Furoate Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Fluticasone Furoate Spray. Talk to your pharmacist if you have questions about this information.
You will need to prime Fluticasone Furoate Spray before you use it for the first time. To prime Fluticasone Furoate Spray, shake it well then spray 6 test sprays in to the air away from your face. You will need to re-prime the medicine if it is not used for 30 days or longer or if the cap is left off the bottle for 5 days or longer
Shake Fluticasone Furoate Spray well before each use.
To use Fluticasone Furoate Spray, gently blow your nose. Remove the cap and hold the spray device upright. Tilt your head forward slightly and place the nozzle in one nostril. Point the end of the nozzle toward the side of your nose (away from the center of your nose). Firmly press the mist release button while breathing in gently through your nose, then remove the nozzle from your nose and breathe out through your mouth. Repeat these steps for the other nostril. After you finish your dose, wipe the nozzle with a clean, dry tissue and replace the cap.
Clean the inside of the cap once a week with a clean, dry tissue. Never try to clean the nozzle with a pin or anything sharp; doing so may damage the nozzle.
Use Fluticasone Furoate Spray on a regular schedule to get the most benefit from it. Using Fluticasone Furoate Spray at the same time each day will help you remember to use it.
Symptoms may begin to improve within 24 hours after you start Fluticasone Furoate Spray. However, it may take several days before you notice the full benefit of Fluticasone Furoate Spray. If symptoms do not improve or if the condition worsens, contact your health care provider. Continue to use Fluticasone Furoate Spray even if you feel well. Do not miss any doses.
If you miss a dose of Fluticasone Furoate Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone Furoate Spray.

Important safety information:

Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone Furoate Spray. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Tell your doctor or dentist that you take Fluticasone Furoate Spray before you receive any medical or dental care, emergency care, or surgery.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If you have NOT had chickenpox or measles, avoid contact with anyone who does. Contact your doctor right away if you are exposed to anyone with these conditions.
Avoid spraying in the eyes.
Fluticasone Furoate Spray should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone Furoate Spray.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone Furoate Spray while you are pregnant. It is not known if Fluticasone Furoate Spray is found in breast milk. If you are or will be breast-feeding while you use Fluticasone Furoate Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fluticasone Furoate Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; cough; headache; minor nosebleed; sore throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; severe or persistent nosebleed; severe or persistent pain in the nose or throat; slow wound healing; vision changes.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fluticasone Furoate Spray:

Store Fluticasone Furoate Spray between 39 and 86 degrees F (4 and 30 degrees C). Store in the upright position with the cap in place. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fluticasone Furoate Spray out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone Furoate Spray, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone Furoate Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone Furoate Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Fluticasone HFA Aerosol Inhaler

30/06/10

Generic Name: Fluticasone HFA (floo-TIK-a-sone)
Brand Name: Flovent HFA

Fluticasone HFA Aerosol Inhaler is used for:

Preventing or reducing the frequency and seriousness of asthma attacks. Fluticasone HFA Aerosol Inhaler will NOT help to stop an asthma attack once one starts.

Fluticasone HFA Aerosol Inhaler is a corticosteroid. It works by reducing inflammation in the airway.

Do NOT use Fluticasone HFA Aerosol Inhaler if:

you are allergic to any ingredient in Fluticasone HFA Aerosol Inhaler
you are having a severe asthma attack requiring quick relief

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone HFA Aerosol Inhaler:

Some medical conditions may interact with Fluticasone HFA Aerosol Inhaler. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have active or inactive tuberculosis (TB) or a history of a positive skin test for TB
if you have an infection of the airways or lungs, untreated fungal or bacterial infections, parasitic or viral infections, measles, chickenpox, or a herpes simplex infection in or around the eye, or if you have recently received a vaccination
if you have diarrhea, glaucoma, or cataracts

Some MEDICINES MAY INTERACT with Fluticasone HFA Aerosol Inhaler. Tell your health care provider if you are taking any other medicines, especially any of the following:

Certain medicines that act on the liver (eg, ketoconazole, ritonavir) because they may increase the actions of Fluticasone HFA Aerosol Inhaler and the risk of Fluticasone HFA Aerosol Inhaler’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone HFA Aerosol Inhaler may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone HFA Aerosol Inhaler:

Use Fluticasone HFA Aerosol Inhaler as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Fluticasone HFA Aerosol Inhaler. Talk to your pharmacist if you have questions about this information.
You must prime the inhaler before you use it for the first time. To prime the inhaler, remove the mouthpiece cap and shake the inhaler well for 5 seconds. Spray the inhaler into the air away from your face and eyes. Repeat 3 more times to finish priming it.
You will need to prime the inhaler again if you go without using it for more than 7 days or if you drop it. To prime the inhaler again, take the cap off the mouthpiece and shake the inhaler well for 5 seconds. Spray it 1 time into the air away from your face and eyes.
For best results, the canister should be at room temperature before use.
Before using Fluticasone HFA Aerosol Inhaler, be sure that the canister is properly placed in the inhaler unit. Shake well before each use. Breathe out slowly and completely. Place the mouthpiece between your lips and try to rest your tongue flat, unless your doctor has told you otherwise. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time. This will release a dose of Fluticasone HFA Aerosol Inhaler. Continue breathing in slowly and deeply and hold for as long as comfortable, then breathe out slowly through pursed lips or your nose. If more than 1 inhalation is to be used, wait a few minutes and repeat the above steps. Keep the spray away from your eyes.
After inhaling, rinse your mouth with water and spit it out.
Keep track of the number of sprays you use and subtract this number from the number of doses in the container. This will help you know when the container is becoming empty.
Continue to use Fluticasone HFA Aerosol Inhaler even if you feel well. Do not miss any doses.
If you miss a dose of Fluticasone HFA Aerosol Inhaler, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone HFA Aerosol Inhaler.

Important safety information:

Fluticasone HFA Aerosol Inhaler is used to prevent asthma attacks. Do NOT use Fluticasone HFA Aerosol Inhaler to treat a severe asthma attack that requires quick relief.
If you are also using a bronchodilator inhaler, be sure to always carry the bronchodilator inhaler with you to use if you have an asthma attack.
Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone HFA Aerosol Inhaler. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Improvement may be noticeable within the first 1 or 2 days of starting Fluticasone HFA Aerosol Inhaler. However, you may need to use Fluticasone HFA Aerosol Inhaler for 1 to 2 weeks before the full benefit is achieved.
Do NOT take more than the recommended dose without checking with your doctor.
Contact your health care provider right away if you experience an asthma attack that does not improve with bronchodilator therapy (eg, albuterol).
Some patients may have trouble using Fluticasone HFA Aerosol Inhaler correctly. Some may also get mouth sores or a bad taste in the mouth after using it. If you have any of these problems, ask your health care provider if a spacing device may help.
If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.
Tell your doctor or dentist that you take Fluticasone HFA Aerosol Inhaler before you receive any medical or dental care, emergency care, or surgery.
Fluticasone HFA Aerosol Inhaler should be used with extreme caution in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone HFA Aerosol Inhaler.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone HFA Aerosol Inhaler while you are pregnant. It is not known if Fluticasone HFA Aerosol Inhaler is found in breast milk. If you are or will be breast-feeding while you use Fluticasone HFA Aerosol Inhaler, check with your doctor. Discuss any possible risks to your baby.

Contact your health care provider if WITHDRAWAL symptoms (joint or muscle pain, lack of energy, depression) occur.

Possible side effects of Fluticasone HFA Aerosol Inhaler:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry mouth; flu; headache; hoarseness; mouth or throat irritation; nasal discharge; runny nose; sinus swelling; sore throat; stuffy nose; upper respiratory tract infection.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; lack of energy; nausea; severe dizziness; slowed growth in children; sudden weight loss; tingling of the arms and legs; tiredness; vision changes; vomiting; weakness; wheezing; white patches or sores in the mouth.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fluticasone HFA Aerosol Inhaler:

Store Fluticasone HFA Aerosol Inhaler at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store canister with mouthpiece down. Store away from heat and direct sunlight. Do not puncture, break, or burn the canister even if it appears to be empty. Contents are under pressure. Keep Fluticasone HFA Aerosol Inhaler out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone HFA Aerosol Inhaler, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone HFA Aerosol Inhaler is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone HFA Aerosol Inhaler. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Fluticasone Powder

30/06/10

Generic Name: Fluticasone (floo-TICK-ah-ZONE)
Brand Name: Examples include Flovent Diskus and Flovent Rotadisk

Fluticasone Powder is used for:

Preventing asthma attacks. Fluticasone Powder will not stop an asthma attack once one has started. It may also be used to treat other conditions as determined by your doctor.

Fluticasone Powder is a corticosteroid. It works by decreasing the irritation and swelling of the breathing tubes (bronchial tubes) of the lung to control or prevent asthma symptoms.

Do NOT use Fluticasone Powder if:

you are allergic to any ingredient in Fluticasone Powder
you are having a severe asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone Powder:

Some medical conditions may interact with Fluticasone Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have glaucoma; cataracts; a bacterial, fungal, parasitic, or viral infection; measles; chicken pox; shingles; tuberculosis (TB); a positive TB skin test; diarrhea; or a herpes infection in the eye; or if you have recently received a vaccination

Some MEDICINES MAY INTERACT with Fluticasone Powder. Tell your health care provider if you are taking any other medicines, especially any of the following:

Certain medicine that act on the liver (eg, protease inhibitors [eg, ritonavir], ketoconazole) because they may increase the actions and side effects of Fluticasone Powder

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone Powder may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone Powder:

Use Fluticasone Powder as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Fluticasone Powder. Talk to your pharmacist if you have questions about this information.
Fluticasone Powder is for oral inhalation only.
If you use 2 inhalations for a dose, use the first and wait at least 30 seconds before using the second inhalation.
Do not use Fluticasone Powder with a spacer device.
Rinse your mouth out or gargle with water after using Fluticasone Powder to prevent mouth sores or a bad aftertaste.
If you miss a dose of Fluticasone Powder, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone Powder.

Important safety information:

Fluticasone Powder is used to prevent the occurrence of asthma attacks. It is not to be used for a severe asthma attack that requires quick relief. Ask your doctor to provide you with another medicine that is used to relieve sudden asthma attacks.
Avoid exposure to chicken pox and measles. If exposed, contact your doctor at once.
If you are also using a bronchodilator inhaler, be sure to always carry the inhaler with you to use during asthma attacks.
Always have a spare inhaler available in case the unit malfunctions or is empty.
Tell your doctor or dentist that you take Fluticasone Powder before you receive any medical or dental care, emergency care, or surgery.
Diabetes patients – Fluticasone Powder may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
After you begin using Fluticasone Powder, a few weeks may pass before the full benefit is obtained. Continue to use it as directed during this time.
Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone Powder. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Fluticasone Powder should not be used in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone Powder.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone Powder while you are pregnant. It is not known if Fluticasone Powder is found in breast milk. If you are or will be breast-feeding while you use Fluticasone Powder, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fluticasone Powder:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back problems; bronchitis; cough; diarrhea; difficulty speaking; dry mouth; fever; flu; headache; hoarseness; muscle pain; nausea; oral yeast infection; runny nose; sinus inflammation; sore throat; stomach pain or discomfort; stuffy nose; throat irritation; upper respiratory tract infection.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); cataracts; choking; fainting; growth suppression in children; irregular heartbeat; numbness or tingling in arms or legs; pounding in the chest; severe dizziness; sudden weight loss; swelling of the throat; unusual weakness; vomiting; wheezing; white curd-like patches in the mouth; worsening of asthma.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fluticasone Powder:

Store Fluticasone Powder at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from direct sunlight, heat, and moisture. Do not store in the bathroom. The inhalation device is not reusable. Inhalation devices should be thrown away 2 months after the foil over-wrap is opened or on the expiration date (whichever comes first). Place the sticker provided with the product on the tube and enter the date the foil over-wrap is opened. Do not puncture any of the blisters until you are ready to take a dose. Keep Fluticasone Powder out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone Powder, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone Powder is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone Powder. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Fluticasone Cream

30/06/10

Generic Name: Fluticasone (floo-TIK-a-sone)
Brand Name: Cutivate

Fluticasone Cream is used for:

Treating inflammation and itching caused by certain skin conditions. It may also be used for other conditions as determined by your doctor.

Fluticasone Cream is a topical corticosteroid. It works by reducing skin inflammation (redness, swelling, itching, and irritation).

Do NOT use Fluticasone Cream if:

you are allergic to any ingredient in Fluticasone Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone Cream:

Some medical conditions may interact with Fluticasone Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines or other substances
if you have an acne-like rash, rosacea, inflammation around the mouth, skin thinning, a skin infection, measles, tuberculosis (TB), chickenpox, shingles, or a positive TB skin test
if you are taking an oral corticosteroid (eg, prednisone) or similar medicines

Some MEDICINES MAY INTERACT with Fluticasone Cream. However, no specific interactions with Fluticasone Cream are known at this time.

Ask your health care provider if Fluticasone Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone Cream:

Use Fluticasone Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Apply a small amount of medicine to the affected area. Gently rub it in until it is evenly distributed.
Wash your hands after you apply Fluticasone Cream, unless your hands are part of the treated area.
Do not bandage or cover the treated skin area unless directed by your doctor.
If you miss a dose of Fluticasone Cream, apply it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not apply 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone Cream.

Important safety information:

Fluticasone Cream is for external use only. Do not get it in your eyes, nose, vagina, or mouth. If you get it in any of these areas, rinse right away with cool water.
Do not use Fluticasone Cream on the face, in the groin area, or under the armpits unless your doctor tells you otherwise.
Do not apply Fluticasone Cream in the diaper area unless your doctor tells you otherwise. If Fluticasone Cream is applied to the diaper area, apply a very small amount and do not use tight-fitting undergarments or plastic pants.
Do not use more than the recommended dose or use for longer than prescribed without checking with you doctor.
If your symptoms do not get better within 2 weeks or if they get worse, check with your doctor.
Contact your doctor if you have a cut or sore that does not heal.
Check with your doctor before you have any vaccines while you are using Fluticasone Cream.
Do not apply Fluticasone Cream over large areas of the body without first checking with your doctor.
Do not use Fluticasone Cream for other skin conditions at a later time.
Do not use other medicines or products on your skin without first checking with your doctor.
Overuse of topical products may worsen your condition.
Fluticasone Cream is a corticosteroid. Before you begin too use any new prescription or nonprescription medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
Tell your doctor or dentist that you take Fluticasone Cream before you receive any medical or dental care, emergency care, or surgery.
Serious side effects may occur if too much of Fluticasone Cream is absorbed through the skin. This may be more likely to occur if you use Fluticasone Cream over a large area of the body. It may also be more likely if you wrap or bandage the area after you apply Fluticasone Cream. The risk is greater in children. Do not use more than the prescribed dose. Contact your doctor right away if you develop unusual weight gain (especially in the face), muscle weakness, increased thirst or urination, confusion, unusual drowsiness, severe or persistent headache, or vision changes. Discuss any questions or concerns with your doctor.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while using a corticosteroid.
Fluticasone Cream should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone Cream while you are pregnant. It is not known if Fluticasone Cream is found in breast milk after topical use. If you are or will be breast-feeding while you use Fluticasone Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fluticasone Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; mild stinging, burning, or itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning, cracking, irritation, or peeling not present before you began using Fluticasone Cream; excessive hair growth; inflamed hair follicles; inflammation around the mouth; thinning, softening, or discoloration of the skin.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision or other vision changes; muscle weakness; severe or persistent headache; symptoms of high blood sugar (eg, increased thirst or urination, confusion, unusual drowsiness); unusual weight gain, especially in the face.

Proper storage of Fluticasone Cream:

Store Fluticasone Cream between 36 and 86 degrees F (2 and 30 degrees C). Store away from heat and light. Keep Fluticasone Cream out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone Cream, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Fluticasone Spray

30/06/10

Generic Name: Fluticasone (floo-TIK-a-sone)
Brand Name: Flonase

Fluticasone Spray is used for:

Treatment of allergic and nonallergic nasal symptoms including congestion, sneezing, itching, and runny nose.

Fluticasone Spray is a corticosteroid. It works by reducing inflammatory reactions in the nasal airway in response to allergens and irritants in the air.

Do NOT use Fluticasone Spray if:

you are allergic to any ingredient in Fluticasone Spray

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone Spray:

Some medical conditions may interact with Fluticasone Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines or other substances
if you have recently experienced an ulcer of the nasal septum, nasal surgery, or nasal trauma
if you have active or inactive tuberculosis or a positive skin test for tuberculosis
if you have infections of the respiratory tract, untreated fungal or bacterial infections, parasitic or viral infections, measles, chickenpox, herpes simplex in or around the eye, or recently received a vaccination
if you have diarrhea
if you have glaucoma or cataracts

Some MEDICINES MAY INTERACT with Fluticasone Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

Certain medicines that act on the liver (eg, protease inhibitors [eg, ritonavir], ketoconazole) because they may increase the actions and the risk of Fluticasone Spray’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone Spray:

Use Fluticasone Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Fluticasone Spray. Talk to your pharmacist if you have questions about this information.
Shake gently before each use.
If needed, prime the spray pump according to the directions in the extra patient leaflet.
To use a nose spray, gently blow your nose. Sit down and tilt your head back slightly. Place the tip of the spray container into the nose. Using a finger from your other hand, press against the opposite nostril to close it off. Breathe gently through the open nostril and squeeze the spray container. If you are using more than 1 spray, wait for 1 to 2 minutes between sprays. After using the medicine, rinse the tip of the spray unit in hot water and dry with a clean tissue to prevent contamination.
Symptoms can start to improve as soon as 12 hours after you start using Fluticasone Spray, and should improve within a couple of days. The full benefit may not be achieved until you have used Fluticasone Spray for several days. If symptoms do not improve or if the condition worsens, contact your health care provider.
Use Fluticasone Spray on a regular schedule to get the most benefit from it.
Using Fluticasone Spray at the same time each day will help you remember to use it.
Continue to use Fluticasone Spray even if you feel well. Do not miss any doses.
If you miss a dose of Fluticasone Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone Spray.

Important safety information:

Fluticasone Spray may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Fluticasone Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone Spray. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Tell your doctor or dentist that you take Fluticasone Spray before you receive any medical or dental care, emergency care, or surgery.
If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.
Avoid spraying in the eyes.
Fluticasone Spray should not be used in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone Spray.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone Spray while you are pregnant. It is not known if Fluticasone Spray is found in breast milk. If you are or will be breast-feeding while you use Fluticasone Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fluticasone Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nasal irritation or burning; nausea; nosebleed; sore throat; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blurred vision or other vision changes; frequent, severe, or persistent nosebleeds or nasal irritation; loss of sense of smell or taste; shortness of breath; sores in the nose; unusual nasal discharge; voice changes; wheezing.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fluticasone Spray:

Store Fluticasone Spray between 39 and 86 degrees F (4 and 30 degrees C). Keep Fluticasone Spray out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone Spray, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Fluticasone Aerosol Inhaler

30/06/10

Generic Name: Fluticasone (flue-TIK-a-sone)
Brand Name: Flovent

Fluticasone Aerosol Inhaler is used for:

Preventing or reducing the frequency and seriousness of bronchial asthma attacks. Fluticasone Aerosol Inhaler does not help during an acute asthma attack.

Fluticasone Aerosol Inhaler is a corticosteroid. It works by reducing inflammatory reactions in the airways in response to allergens and irritants in the air.

Do NOT use Fluticasone Aerosol Inhaler if:

you are allergic to any ingredient in Fluticasone Aerosol Inhaler
you are having a severe asthma attack requiring quick relief

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fluticasone Aerosol Inhaler:

Some medical conditions may interact with Fluticasone Aerosol Inhaler. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, plan to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines or other substances
if you have active or inactive tuberculosis or a positive skin test for tuberculosis
if you have infections of the respiratory tract, untreated fungal or bacterial infections, parasitic or viral infections, measles, chickenpox, herpes simplex in or around the eye, or recently received a vaccination
if you have diarrhea
if you have glaucoma or cataracts

Some MEDICINES MAY INTERACT with Fluticasone Aerosol Inhaler. Tell your health care provider if you are taking any other medicines, especially any of the following:

Certain medicines that act on the liver (eg, protease inhibitors [eg, ritonavir], ketoconazole) because they may increase the actions and side effects of Fluticasone Aerosol Inhaler

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fluticasone Aerosol Inhaler may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fluticasone Aerosol Inhaler:

Use Fluticasone Aerosol Inhaler as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Fluticasone Aerosol Inhaler. Talk to your pharmacist if you have questions about this information.
If needed, prime the inhaler according to the directions in the extra patient leaflet.
For best results, the canister should be at room temperature before use.
Before using Fluticasone Aerosol Inhaler, be sure that the canister is properly placed in the inhaler unit. Shake well before each use. Breathe out slowly and completely. Place the mouthpiece between your lips and try to rest your tongue flat, unless your doctor has told you otherwise. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time. This will release a dose of Fluticasone Aerosol Inhaler. Continue breathing in slowly and deeply and hold for as long as comfortable, then breathe out slowly through pursed lips or your nose. If more than 1 inhalation is to be used, wait a few minutes and repeat the above steps. Keep the spray away from your eyes.
After inhaling, rinse your mouth with water without swallowing.
Keep track of the number of sprays you use and subtract this number from the number of doses in the container. This will help you know when the container is becoming empty.
Continue to use Fluticasone Aerosol Inhaler even if you feel well. Do not miss any doses.
If you miss a dose of Fluticasone Aerosol Inhaler, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluticasone Aerosol Inhaler.

Important safety information:

Fluticasone Aerosol Inhaler is used to prevent asthma attacks. It is not to be used for a severe asthma attack that requires quick relief.
If you are also using a bronchodilator inhaler, be sure to always carry the bronchodilator inhaler with you to use during asthma attacks.
Use caution if you switch from an oral steroid (eg, prednisone) to Fluticasone Aerosol Inhaler. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Improvement may be noticeable within the first day or 2 of using Fluticasone Aerosol Inhaler. However, you may need to use Fluticasone Aerosol Inhaler for 1 to 2 weeks before the full benefit is achieved.
If your symptoms do not get better or if they get worse, check with your doctor.
Some patients may have trouble using Fluticasone Aerosol Inhaler correctly. Some may also get mouth sores or a bad taste in the mouth after using it. If you have any of these problems, ask your health care provider if a spacing device may help.
Contact your health care provider at once if episodes of asthma that are not responsive to bronchodilators occur.
Contact your health care provider at once if signs of an infection occur.
If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.
Tell your doctor or dentist that you take Fluticasone Aerosol Inhaler before you receive any medical or dental care, emergency care, or surgery.
Fluticasone Aerosol Inhaler is for oral inhalation only. Avoid spraying in the eyes.
Fluticasone Aerosol Inhaler should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Fluticasone Aerosol Inhaler.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fluticasone Aerosol Inhaler while you are pregnant. It is not known if Fluticasone Aerosol Inhaler is found in breast milk. If you are or will be breast-feeding while you use Fluticasone Aerosol Inhaler, check with your doctor. Discuss any possible risks to your baby.

Contact your health care provider if WITHDRAWAL symptoms (joint or muscle pain, lack of energy, depression) occur.

Possible side effects of Fluticasone Aerosol Inhaler:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry mouth; flu; headache; hoarseness; nasal discharge; runny nose; sinus swelling; sore throat; stuffy nose; upper respiratory tract infection.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; lack of energy; nausea; severe dizziness; slowed growth in children; sudden weight loss; tingling of the arms and legs; tiredness; vomiting; weakness; wheezing; white curd-like patches in the mouth.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Fluticasone Aerosol Inhaler:

Store Fluticasone Aerosol Inhaler between 36 and 86 degrees F (2 and 30 degrees C). Protect from freezing. Store canister with mouthpiece down. Store away from heat and direct sunlight. Do not puncture, break, or burn the canister even if it appears to be empty. Contents are under pressure. Keep Fluticasone Aerosol Inhaler out of the reach of children and away from pets.

General information:

If you have any questions about Fluticasone Aerosol Inhaler, please talk with your doctor, pharmacist, or other health care provider.
Fluticasone Aerosol Inhaler is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Fluticasone Aerosol Inhaler. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

F,Med-facts

Comments (0)

Page 20 of 64« First...10 «16 17 18 192021 22 23 24 25 »30 40 50...Last »

Drugs & Medications:A-Z

Recent Posts

Blogroll

30/06/10

Fluticasone/ Salmeterol Powder

Fluticasone/Salmeterol Powder is used for:

Do NOT use Fluticasone/Salmeterol Powder if:

Before using Fluticasone/Salmeterol Powder:

How to use Fluticasone/Salmeterol Powder:

Important safety information:

Possible side effects of Fluticasone/Salmeterol Powder:

If OVERDOSE is suspected:

General information:

30/06/10

What is fluticasone and salmeterol inhalation?

What is the most important information I should know about fluticasone and salmeterol?

What should I discuss with my healthcare provider before using this medication?

How should I use this medication?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using this medication?

This medication side effects

Fluticasone and salmeterol Dosing Information

What other drugs will affect this medication?

Where can I get more information?

30/06/10

Uses For fluticasone and salmeterol

Before Using fluticasone and salmeterol

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of fluticasone and salmeterol

Dosing

Missed Dose

Storage

Precautions While Using fluticasone and salmeterol

fluticasone and salmeterol Side Effects

30/06/10

Uses For fluticasone furoate

Before Using fluticasone furoate

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of fluticasone furoate

Dosing

Missed Dose

Storage

Precautions While Using fluticasone furoate

fluticasone furoate Side Effects

30/06/10

Fluticasone Furoate Spray is used for:

Do NOT use Fluticasone Furoate Spray if:

Before using Fluticasone Furoate Spray:

How to use Fluticasone Furoate Spray:

Important safety information:

Possible side effects of Fluticasone Furoate Spray:

If OVERDOSE is suspected:

General information:

30/06/10

Fluticasone HFA Aerosol Inhaler is used for:

Do NOT use Fluticasone HFA Aerosol Inhaler if:

Before using Fluticasone HFA Aerosol Inhaler:

How to use Fluticasone HFA Aerosol Inhaler:

Important safety information:

Possible side effects of Fluticasone HFA Aerosol Inhaler:

If OVERDOSE is suspected:

General information:

30/06/10

Fluticasone Powder is used for:

Do NOT use Fluticasone Powder if:

Fluticasone/

Salmeterol Powder