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Guaifenesin Sustained-Release Tablets

30/06/10

Generic Name: Guaifenesin (gwye-FEN-eh-sin)
Brand Name: Mucinex

Guaifenesin Sustained-Release Tablets are used for:

Relieving symptoms of cough and mucus in the chest due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Guaifenesin Sustained-Release Tablets are an expectorant. It works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up. This reduces chest congestion by making coughs more productive.

Do NOT use Guaifenesin Sustained-Release Tablets if:

you are allergic to any ingredient in Guaifenesin Sustained-Release Tablets

Contact your doctor or health care provider right away if any of these apply to you.

Before using Guaifenesin Sustained-Release Tablets:

Some medical conditions may interact with Guaifenesin Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a chronic cough that occurs with smoking, asthma, chronic bronchitis, or emphysema, or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Guaifenesin Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines. However, no specific interactions with Guaifenesin Sustained-Release Tablets are known at this time.

Ask your health care provider if Guaifenesin Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Guaifenesin Sustained-Release Tablets:

Use Guaifenesin Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Guaifenesin Sustained-Release Tablets by mouth with or without food.
Drinking extra fluids while you are taking Guaifenesin Sustained-Release Tablets are recommended. Check with your doctor for instructions.
Swallow Guaifenesin Sustained-Release Tablets whole. Do not break, crush, or chew before swallowing.
If you miss a dose of Guaifenesin Sustained-Release Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Guaifenesin Sustained-Release Tablets.

Important safety information:

If cough persists for more than 1 week or is accompanied by a fever, contact your health care provider. A persistent cough could be a sign of a serious condition.
Different brands of Guaifenesin Sustained-Release Tablets may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Guaifenesin Sustained-Release Tablets while you are pregnant. It is not known if Guaifenesin Sustained-Release Tablets are found in breast milk. If you are or will be breast-feeding while you are using Guaifenesin Sustained-Release Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Guaifenesin Sustained-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Guaifenesin Sustained-Release Tablets:

Store Guaifenesin Sustained-Release Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Guaifenesin Sustained-Release Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Guaifenesin Sustained-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
Guaifenesin Sustained-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Guaifenesin Sustained-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

G,Med-facts

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Griseofulvin Microsize Tablets

30/06/10

Generic Name: Griseofulvin (GRIS-ee-oh-FUL-vin)
Brand Name: Grifulvin V

Griseofulvin Microsize Tablets are used for:

Treating ringworm infections of the skin, hair, and nails. It is also used to treat athlete’s foot and “barber’s itch.” It may also be used for other conditions as determined by your doctor.

Griseofulvin Microsize Tablets are an antifungal agent. It works by making the skin more resistant to fungal growth.

Do NOT use Griseofulvin Microsize Tablets if:

you are allergic to any ingredient in Griseofulvin Microsize Tablets
you have liver failure or a blood disease (eg, porphyria)
you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Griseofulvin Microsize Tablets:

Some medical conditions may interact with Griseofulvin Microsize Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have liver disease or lupus

Some MEDICINES MAY INTERACT with Griseofulvin Microsize Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital) because they may decrease Griseofulvin Microsize Tablets’s effectiveness
Anticoagulants (eg, warfarin) or oral contraceptives (birth control pills) because their effectiveness may be decreased by Griseofulvin Microsize Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Griseofulvin Microsize Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Griseofulvin Microsize Tablets:

Use Griseofulvin Microsize Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Griseofulvin Microsize Tablets by mouth with food or milk, unless otherwise directed by your doctor.
To clear up your infection completely, take Griseofulvin Microsize Tablets for the full course of treatment. Keep taking it even if you feel better in a few days.
If you miss a dose of Griseofulvin Microsize Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Griseofulvin Microsize Tablets.

Important safety information:

Griseofulvin Microsize Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Griseofulvin Microsize Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Be sure to use Griseofulvin Microsize Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
Do not drink alcohol while you are taking Griseofulvin Microsize Tablets.
Griseofulvin Microsize Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Griseofulvin Microsize Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
It is important to practice good hygiene during and after use to prevent reinfection.
Hormonal birth control (eg, birth control pills) may not work as well while you are using Griseofulvin Microsize Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).
Griseofulvin Microsize Tablets should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Griseofulvin Microsize Tablets if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Griseofulvin Microsize Tablets are found in breast milk. If you are or will be breast-feeding while you use Griseofulvin Microsize Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Griseofulvin Microsize Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; fever; flu-like symptoms (eg, headache, joint pain); numbness or tingling in the hands or feet; sore throat; white patches in the mouth.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Griseofulvin Microsize Tablets:

Store Griseofulvin Microsize Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Griseofulvin Microsize Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Griseofulvin Microsize Tablets, please talk with your doctor, pharmacist, or other health care provider.
Griseofulvin Microsize Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Griseofulvin Microsize Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

G,Med-facts

Comments (0)

growth hormone (Parenteral route)

30/06/10

Uses For growth hormone

Somatrem and somatropin are man-made versions of human growth hormone. Growth hormone is naturally produced by the pituitary gland and is necessary to stimulate growth in children. Man-made growth hormone may be used in children who have certain conditions that cause failure to grow normally. These conditions include growth hormone deficiency (inability to produce enough growth hormone), kidney disease, Prader-Willi Syndrome (PWS), and Turner’s syndrome. Growth hormone is also used in adults to treat growth failure and to treat weight loss caused by acquired immunodeficiency syndrome (AIDS).

growth hormone is available only with your doctor’s prescription.

Before Using growth hormone

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing use of growth hormone in children with acquired immunodeficiency syndrome (AIDS) with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of growth hormone in the elderly with use in other age groups, it is not expected to cause different side effects or problems in older people than it does in younger adults. However, elderly patients may be more sensitive to the action of growth hormone drugs and may be more at risk to develop adverse reactions.

Pregnancy

Growth hormone has not been studied in pregnant women. However, in animal studies, growth hormone has not been shown to cause birth defects or other problems. This drug should be used during pregnancy only if clearly needed. Tell your doctor if you are pregnant or plan on becoming pregnant.

Breast Feeding

It is not known whether growth hormone passes into breast milk. However, you should tell your doctor if you are nursing.

Interactions with Medicines

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

Rotavirus Vaccine, Live

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Bupropion

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of growth hormone

Some medicines given by injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using growth hormone at home, your health care professional will teach you how to prepare and inject the medicine. You will have a chance to practice preparing and injecting it. Be certain that you understand exactly how the medicine is to be prepared and injected.

It is important to read the patient information and instructions for use, if provided with your medicine, each time your prescription is filled.

It is important to follow any instructions from your doctor about the careful selection and rotation of injection sites on your body. This will help to prevent skin problems.

Put used needles and syringes in a puncture-resistant disposable container or dispose of them as directed by your health care professional. Do not reuse needles and syringes.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For somatrem
For injection dosage form:
- For treatment of growth failure caused by growth hormone deficiency:
  - Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.3 milligram (mg) per kilogram (kg) (0.136 mg per pound) of body weight. This is divided into smaller doses and usually is injected under the skin, but may be injected into a muscle as determined by your doctor.

For somatropin
For injection dosage form:
- For treatment of growth failure caused by growth hormone deficiency:
  - Adults—Dose is based on body weight and must be determined by your doctor. At first, it is usually 0.005 milligram (mg) per kilogram (kg) (0.0023 mg per pound) of body weight injected under the skin once a day. Your doctor may then increase the dose if needed.
  - Adults using Norditropin Cartridges or Norditropin NordiFlex—Dose is based on body weight and must be determined by your doctor. At first, it is usually 0.004 milligram (mg) per kilogram (kg) (0.0002 mg per pound) of body weight injected under the skin once a day. Your doctor may then increase the dose if needed. The dose is given using a NordiPen injection device for Norditropin cartridges and a prefilled pen for Norditropin NordiFlex.
  - Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.16 to 0.3 mg per kg (0.073 to 0.136 mg per pound) of body weight. This is divided into smaller doses and usually is injected under the skin, but may be injected into a muscle as determined by your doctor.
  - Children using Norditropin Cartridges or Norditropin NordiFlex—Dose is based on body weight and must be determined by your doctor. The usual dose is 0.024 to 0.034 mg per kg (0.011 to 0.015 mg per pound of body weight) injected under the skin, on 6 to 7 days a week. The dose is given using a NordiPen injection device for Norditropin cartridges and a prefilled pen for Norditropin NordiFlex.
- For treatment of growth failure caused by kidney disease:
  - Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.35 mg per kg (0.16 mg per pound) of body weight. This is divided into smaller daily doses and is injected under the skin or into a muscle.
- For treatment of growth failure caused by Turner’s syndrome:
  - Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.375 mg per kg (0.17 mg per pound) of body weight. This is divided into smaller doses and is injected under the skin.
- For treatment of growth failure caused by Prader-Willi syndrome:
  - Children—Dose is based on body weight and must be determined by your doctor. The usual total weekly dose is 0.24 mg per kg (0.11 mg per pound) of body weight. This is divided into 6 or 7 smaller doses over the course of the week and is injected under the skin.
- For treatment of weight loss caused by acquired immunodeficiency disease (AIDS):
  - Adults weighing more than 121 pounds (55 kg)—6 mg injected under the skin once a day at bedtime.
  - Adults weighing 99 to 121 pounds (45 to 55 kg)—5 mg injected under the skin once a day at bedtime.
  - Adults weighing 77 to 98 pounds (35 to 44 kg)—4 mg injected under the skin once a day at bedtime.
  - Adults weighing less than 77 pounds (35 kg)—Dose is based on body weight and must be determined by your doctor. It is usually 0.1 mg per kg (0.045 mg per pound) of body weight injected under the skin once a day at bedtime.
  - Children—Use and dose must be determined by your doctor.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Store at temperature directed by your health care professional or the manufacturer.

Precautions While Using growth hormone

It is important that your doctor check your progress at regular visits.

growth hormone Side Effects

Leukemia has been reported in a few patients after treatment with growth hormone. However, it is not definitely known whether the leukemia was caused by the growth hormone. Leukemia has also been reported in patients whose bodies do not make enough growth hormone and who have not yet been treated with man-made growth hormone. However, discuss this possible effect with your doctor.

If growth hormone is given to children or adults with normal growth, who do not need growth hormone, serious unwanted effects may occur because levels in the body become too high. These effects include the development of diabetes; abnormal growth of bones and internal organs such as the heart, kidneys, and liver; atherosclerosis (hardening of the arteries); and hypertension (high blood pressure).

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Abnormal or decreased touch sensation
blurred vision
burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
dizziness
ear infection or other ear problems (in patients with Turner’s syndrome)
nervousness
pounding in the ears
severe headache
slow or fast heartbeat

Less common

Chest pain

Rare

Abdominal pain or bloating
changes in vision
depression of skin at place of injection
headache
limp
nausea and vomiting
pain and swelling at place of injection
pain in hip or knee
skin rash or itching

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain
chills
cough or cough producing mucus
constipation
depressed mood
diarrhea
difficulty in breathing
difficulty in moving
dizziness
dry skin and hair
ear congestion
feeling cold
fever
general feeling of discomfort or illness
hair loss
hoarseness or husky voice
loss of appetite
loss of voice
runny nose
shivering
shortness of breath
sore throat
slowed heartbeat
sneezing
stuffy nose
sweating
swollen joints
tightness in chest
trouble sleeping
weight gain
wheezing

Less common or rare

Carpal tunnel syndrome
enlargement of breasts
feeling sad or empty
increased growth of birthmarks
irritability
joint pain
loss of interest or pleasure
muscle pain, cramps, or stiffness
skeletal pain
sleepiness
swelling of hands, feet, or lower legs
trouble concentrating
unable to sleep
unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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Guaiatussin AC

30/06/10

Generic Name: codeine and guaifenesin (KOE deen and gwye FEN a sin)
Brand Names: Allfen CD, Allfen CDX, Brontex, Cheracol with Codeine, Cheratussin AC, Dex-Tuss, Diabetic Tussin C, Duraganidin NR, ExeClear-C, Guaiatussin AC, Guaifen-C, Guiatuss AC, Guiatussin with Codeine, Iophen-C NR, M-Clear WC, Mar-cof CG, Mytussin AC, Robafen AC, Robitussin-AC, Tussi-Organidin NR, Tussi-Organidin-S NR, Tussiden C, Tusso-C

What is Guaiatussin AC (codeine and guaifenesin)?

Codeine is in a group of drugs called narcotics. It is a cough suppressant that affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen mucus congestion in your chest and throat, making it easier to cough out through your mouth.

The combination of codeine and guaifenesin is used to treat cough and to reduce chest congestion caused by upper respiratory infections or the common cold.

Codeine and guaifenesin will not treat a cough that is caused by smoking, asthma, or emphysema.

Codeine and guaifenesin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Guaiatussin AC (codeine and guaifenesin)?

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains guaifenesin. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Codeine may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

What should I discuss with my healthcare provider before taking Guaiatussin AC (codeine and guaifenesin)?

You should not take this medication if you are allergic to codeine or guaifenesin.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take codeine and guaifenesin:

heart disease, heart rhythm disorder;
asthma, COPD, emphysema, or other breathing disorders;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
a stomach or intestinal disorder;
Addison’s disease or other adrenal gland disorders;
curvature of the spine;
a thyroid disorder;
liver or kidney disease;
enlarged prostate; or
a history of depression, mental illness, or drug addiction;

FDA pregnancy category C. This medication may be harmful to an unborn baby, and could cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication if you are breast-feeding a baby. Codeine may be habit-forming and should be used only by the person it was prescribed for. Codeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Older adults may be more likely to have side effects from this medication.

Liquid forms of this medication may contain sugar or artificial sweetener (phenylalanine). Talk to your doctor before using this form of codeine and guaifenesin if you have diabetes or phenylketonuria (PKU).

How should I take Guaiatussin AC (codeine and guaifenesin)?

Take this medication exactly as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Follow the directions on your prescription label. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children. Take codeine and guaifenesin with food if it upsets your stomach. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you also have a fever, headache, or skin rash.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using codeine and guaifenesin.

Do not stop using this medication suddenly after long-term use or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Store codeine and guaifenesin at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Keep track of how much of this medicine has been used from each new bottle. Codeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Since cough medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of codeine can be fatal.

Overdose symptoms may include extreme dizziness or drowsiness, nausea, vomiting, sweating, confusion, hallucinations, cold and clammy skin, blue-colored lips or fingernails, weak or limp muscles, pinpoint pupils, weak pulse, slow breathing, fainting, or seizures (convulsions).

What should I avoid while taking Guaiatussin AC (codeine and guaifenesin)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. Guaifenesin is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains guaifenesin.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Guaiatussin AC (codeine and guaifenesin) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have any of these serious side effects:

severe dizziness or drowsiness;
confusion, hallucinations, unusual thoughts or behavior;
urinating less than usual or not at all; or
slow heart rate, weak pulse, fainting, weak or shallow breathing.

Less serious side effects include:

dizziness, drowsiness, headache;
warmth, redness, or tingling under your skin;
nausea, vomiting, upset stomach;
constipation; or
skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Guaiatussin AC (codeine and guaifenesin)?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine and guaifenesin.

Also tell your doctor if you are using any of the following drugs:

cimetidine (Tagamet);
quinidine (Quinaglute, Quinidex, Quin-Release);
naloxone (Narcan); or
naltrexone (Vivitrol).

This list is not complete and there may be other drugs that can interact with codeine and guaifenesin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about codeine and guaifenesin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,G

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Guaibid DM

30/06/10

Generic Name: dextromethorphan and guaifenesin (DEX troe me THOR fan and gwye FEN e sin)
Brand Names: Allfen DM, Altarussin DM, Aquatab DM, Benylin Expectorant, Drituss DM, Extuss LA, Fenesin DM IR, Glycotuss-DM, Guaifen DM, Mucinex Children’s Cough, Mucinex DM, MucusRelief DM, Naldecon DX Liquigel, Relacon LAX, Respa-DM, Robitussin Cough & Congestion, Tussi-Bid, Tussi-Organidin DM NR, Vicks 44E

What is Guaibid DM (dextromethorphan and guaifenesin)?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

The combination of dextromethorphan and guaifenesin is used to treat cough and chest congestion caused by the common cold, infections, or allergies.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan and guaifenesin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Guaibid DM (dextromethorphan and guaifenesin)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan or guaifenesin. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

What should I discuss with my healthcare provider before taking Guaibid DM (dextromethorphan and guaifenesin)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have emphysema or chronic bronchitis.

FDA pregnancy category C. It is not known whether dextromethorphan and guaifenesin is harmful to an unborn baby. Before you take this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Guaibid DM (dextromethorphan and guaifenesin)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Dextromethorphan and guaifenesin granules should be sprinkled directly onto the tongue and swallowed right away.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medicine at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous.

What should I avoid while taking Guaibid DM (dextromethorphan and guaifenesin)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with cough or cold medicine can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. Dextromethorphan and guaifenesin are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan or guaifenesin.

Guaibid DM (dextromethorphan and guaifenesin) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

severe dizziness, anxiety, restless feeling, or nervousness;
confusion, hallucinations; or
slow, shallow breathing.

Less serious side effects may include:

dizziness;
headache;
skin rash or itching; or
nausea, vomiting, or stomach upset.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Guaibid DM (dextromethorphan and guaifenesin)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

celecoxib (Celebrex);
cinacalcet (Sensipar);
darifenacin (Enablex);
imatinib (Gleevec);
quinidine (Quinaglute, Quinidex);
ranolazine (Ranexa);
ritonavir (Norvir);
sibutramine (Meridia);
terbinafine (Lamisil);
medicines to treat high blood pressure; or
an antidepressant such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others.

This list is not complete and there may be other drugs that can interact with dextromethorphan and guaifenesin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about dextromethorphan and guaifenesin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,G

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Grisactin Ultra

30/06/10

Generic Name: griseofulvin (GRIS ee oh FUL vin)
Brand Names: Fulvicin P/G, Fulvicin U/F, Grifulvin V, Gris-PEG, Grisactin 500, Grisactin Ultra

What is Grisactin Ultra (griseofulvin)?

Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Griseofulvin is used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete’s foot, and barber’s itch.

Griseofulvin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Grisactin Ultra (griseofulvin)?

Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Avoid prolonged exposure to sunlight. Griseofulvin increases sensitivity to sunlight, and severe burning may result.

What should I discuss with my healthcare provider before taking Grisactin Ultra (griseofulvin)?

You cannot take griseofulvin if you

have ever had an allergic reaction to it,
have porphyria, or
have liver disease.

Talk to your doctor before taking griseofulvin if you have any of the conditions listed above.

Griseofulvin is in the FDA pregnancy category C. This means that it is not known whether griseofulvin will harm an unborn baby. In rare cases, the use of griseofulvin has been associated with conjoined twins. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether griseofulvin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Griseofulvin may affect sperm and sperm production. It is recommended that you avoid fathering a child during treatment with griseofulvin and for 6 months following therapy.

How should I take Grisactin Ultra (griseofulvin)?

Take griseofulvin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water. Your doctor may recommend that you take griseofulvin with a fatty meal to increase its absorption into your body. Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of griseofulvin with a dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Store griseofulvin tablets, capsules, and suspension at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Take the rest of the day’s doses at evenly spaced intervals unless your doctor directs otherwise.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a griseofulvin overdose are not well known but might include nausea, vomiting, diarrhea, headache, numbness and tingling, and confusion.

What should I avoid while taking Grisactin Ultra (griseofulvin)?

Avoid prolonged exposure to sunlight. Griseofulvin increases sensitivity to sunlight, and severe burning may result. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. The combination of alcohol and griseofulvin may cause flushing and a fast heart rate. Use alcohol cautiously during treatment with griseofulvin.

Grisactin Ultra (griseofulvin) side effects

Stop taking griseofulvin and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take griseofulvin and notify your doctor if you experience

white patches in your mouth (thrush/yeast infection);
nausea, vomiting, or diarrhea;
headache, dizziness, or tiredness;
insomnia;
confusion;
numbness or tingling in your hands or feet; or
menstrual irregularities.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Grisactin Ultra (griseofulvin)?

Griseofulvin may decrease the effects of the following drugs:

oral anticoagulants (blood thinners) such as warfarin (Coumadin). A decrease in the effectiveness of anticoagulants could lead to blood clotting. It may be necessary to increase anticoagulant dosage.
birth control pills. Decreased effectiveness could lead to break-through bleeding and possibly to an unintended pregnancy. Talk to your doctor about using of other forms of birth control during treatment with griseofulvin.
salicylates such as aspirin, salsalate (Disalcid, Salsitab, Salflex, others), choline salicylate (Arthropan), magnesium salicylate (Doan’s, Magan), and others. Larger doses of these medicines may be needed.
cyclosporine (Sandimmune, Neoral). Your doctor may need to adjust your cyclosporine dosage.

The effects of griseofulvin may be decreased by barbiturates such as phenobarbital (Luminal, Solfoton), pentobarbital (Nembutal), secobarbital (Seconal), amobarbital (Amytal), and butabarbital (Butisol). Larger doses of griseofulvin may be necessary if you are taking any of these drugs.

Drugs other than those listed here may also interact with griseofulvin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist can provide more information about griseofulvin.

Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medicine for the illness your doctor prescribed it for.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,G

Comments (0)

griseofulvin

30/06/10

Generic Name: griseofulvin (GRIS ee oh FUL vin)
Brand names: Fulvicin P/G, Fulvicin U/F, Grifulvin V, Gris-PEG, Grisactin 500, Grisactin Ultra, Grisactin 250, Griseofulicin, Griseofulvic

What is griseofulvin?

Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Griseofulvin is used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete’s foot, and barber’s itch.

Griseofulvin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about griseofulvin?

What should I discuss with my healthcare provider before taking griseofulvin?

You cannot take griseofulvin if you

have ever had an allergic reaction to it,
have porphyria, or
have liver disease.

Talk to your doctor before taking griseofulvin if you have any of the conditions listed above.

How should I take griseofulvin?

Take griseofulvin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Store griseofulvin tablets, capsules, and suspension at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Take the rest of the day’s doses at evenly spaced intervals unless your doctor directs otherwise.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a griseofulvin overdose are not well known but might include nausea, vomiting, diarrhea, headache, numbness and tingling, and confusion.

What should I avoid while taking griseofulvin?

Griseofulvin side effects

Stop taking griseofulvin and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take griseofulvin and notify your doctor if you experience

white patches in your mouth (thrush/yeast infection);
nausea, vomiting, or diarrhea;
headache, dizziness, or tiredness;
insomnia;
confusion;
numbness or tingling in your hands or feet; or
menstrual irregularities.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Griseofulvin Dosing Information

Usual Adult Dose for Onychomycosis — Fingernail:

Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses

Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Onychomycosis — Toenail:

Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses

Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Tinea Pedis:

Microsize formulation: 1000 mg/day orally in 2 to 4 divided doses

Ultramicrosize formulation: 660 to 750 mg/day orally in 2 to 4 divided doses

Usual Adult Dose for Tinea Barbae:

Microsize formulation: 500 mg/day orally in single or 2 divided doses

Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Capitis:

Microsize formulation: 500 mg/day orally in single or 2 divided doses

Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Corporis:

Microsize formulation: 500 mg/day orally in single or 2 divided doses

Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

Usual Adult Dose for Tinea Cruris:

Microsize formulation: 500 mg/day orally in single or 2 divided doses

Ultramicrosize formulation: 330 to 375 mg/day orally in single or divided doses

What other drugs will affect griseofulvin?

Griseofulvin may decrease the effects of the following drugs:

oral anticoagulants (blood thinners) such as warfarin (Coumadin). A decrease in the effectiveness of anticoagulants could lead to blood clotting. It may be necessary to increase anticoagulant dosage.
birth control pills. Decreased effectiveness could lead to break-through bleeding and possibly to an unintended pregnancy. Talk to your doctor about using of other forms of birth control during treatment with griseofulvin.
salicylates such as aspirin, salsalate (Disalcid, Salsitab, Salflex, others), choline salicylate (Arthropan), magnesium salicylate (Doan’s, Magan), and others. Larger doses of these medicines may be needed.
cyclosporine (Sandimmune, Neoral). Your doctor may need to adjust your cyclosporine dosage.

Drugs other than those listed here may also interact with griseofulvin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist can provide more information about griseofulvin.

Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medicine for the illness your doctor prescribed it for.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,G

Comments (0)

griseofulvin (Oral route)

30/06/10

gris-ee-oh-FUL-vin

Commonly used brand name(s):

In the U.S.

Fulvicin P/G
Fulvicin-U/F
Grifulvin V
Gris-PEG

Available Dosage Forms:

Tablet
Capsule
Suspension

Therapeutic Class: Antifungal

Uses For griseofulvin

Griseofulvin belongs to the group of medicines called antifungals. It is used to treat fungus infections of the skin, hair, fingernails, and toenails. griseofulvin may be taken alone or used along with medicines that are applied to the skin for fungus infections.

Griseofulvin is available only with your doctor’s prescription.

Before Using griseofulvin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For griseofulvin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to griseofulvin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

griseofulvin has been tested in a limited number of children 2 years of age or older. In effective doses, the medicine has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of griseofulvin in the elderly with use in other age groups, griseofulvin is not expected to cause different side effects or problems in older people than it does in younger adults.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using griseofulvin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Desogestrel
Ethinyl Estradiol
Etonogestrel
Levonorgestrel
Mestranol
Norelgestromin
Norethindrone
Norgestrel
Phenobarbital
Warfarin

Interactions with Food/Tobacco/Alcohol

Using griseofulvin with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use griseofulvin, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

Proper Use of griseofulvin

Griseofulvin is absorbed best when it is taken with a high fat meal, such as a cheeseburger, whole milk, or ice cream. Tell your doctor if you are on a low-fat diet.

Griseofulvin is best taken with or after meals, especially fatty ones (for example, whole milk or ice cream). This lessens possible stomach upset and helps to clear up the infection by helping your body absorb the medicine better. However, if you are on a low-fat diet, check with your doctor.

For patients taking the oral liquid form of griseofulvin :

Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep taking griseofulvin for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.

Dosing

The dose of griseofulvin will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of griseofulvin. If your dose is different, do not change it unless your doctor tells you to do so.

For microsize capsules, tablets, and suspension:
- Adults and teenagers:
  - Treatment of fungus infections of the feet and nails—500 milligrams (mg) every twelve hours.
  - Treatment of fungus infections of the scalp, skin, and groin—250 mg every twelve hours; or 500 mg once a day.
- Children:
  - Treatment of fungus infections—Dose is based on body weight. The usual dose is 5 mg per kilogram (kg) (2.3 mg per pound) of body weight every twelve hours; or 10 mg per kg (4.6 mg per pound) of body weight once a day.
For ultramicrosize tablets:
- Adults and teenagers:
  - Treatment of fungus infections of the feet and nails—250 to 375 mg every twelve hours.
  - Treatment of fungus infections of the scalp, skin, and groin—125 to 187.5 mg every twelve hours; or 250 to 375 mg once a day.
- Infants and children up to 2 years of age:
  - Treatment of fungus infections—Use and dose must be determined by your doctor.
- Children 2 years of age and over:
  - Treatment of fungus infections—Dose is based on body weight. The usual dose is 2.75 to 3.65 mg per kg (1.25 to 1.7 mg per pound) of body weight every twelve hours; or 5.5 to 7.3 mg per kg (2.5 to 3.3 mg per pound) of body weight once a day.

Missed Dose

If you miss a dose of griseofulvin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using griseofulvin

Your doctor should check your progress at regular visits to make sure that griseofulvin does not cause unwanted effects.

Oral contraceptives (birth control pills) containing estrogen may not work properly if you take them while you are taking griseofulvin. Unplanned pregnancies may occur. You should use a different or additional means of birth control while you are taking griseofulvin and for one month after stopping griseofulvin. If you have any questions about this, check with your health care professional.

Griseofulvin may increase the effects of alcohol. If taken with alcohol it may also cause fast heartbeat, flushing, increased sweating, or redness of the face. Therefore, if you have this reaction, do not drink alcoholic beverages while you are taking griseofulvin, unless you have first checked with your doctor.

griseofulvin may cause some people to become dizzy or less alert than they are normally. Make sure you know how you react to griseofulvin before you drive, use machines, or do other things that could be dangerous if you are dizzy or are not alert. If these reactions are especially bothersome, check with your doctor.

Griseofulvin may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking griseofulvin:

Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat. Also, wear sunglasses.
Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.
Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

griseofulvin Side Effects

Griseofulvin has been shown to cause liver and thyroid tumors in some animals. You and your doctor should discuss the good griseofulvin will do, as well as the risks of taking it.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Confusion
increased sensitivity of skin to sunlight
skin rash, hives, or itching
soreness or irritation of mouth or tongue

Rare

Numbness, tingling, pain, or weakness in hands or feet
sore throat and fever
yellow eyes or skin

More common

Headache

Less common

Diarrhea
dizziness
nausea or vomiting
stomach pain
trouble in sleeping
unusual tiredness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,G

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Griseofulvin Microsize

30/06/10

Generic Name: Griseofulvin (gri-see-oh-FULL-vin)
Brand Name: Generic only. No brands available.

Griseofulvin Microsize is used for:

Treating fungal infections of the scalp, body, foot (athlete’s foot), nails, thigh (jock itch), or hair follicles (barber’s itch).

Griseofulvin Microsize is an antifungal agent. It works by making the skin more resistant to fungal growth.

Do NOT use Griseofulvin Microsize if:

you are allergic to any ingredient in Griseofulvin Microsize
you have severe liver disease or the blood disease porphyria
you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Griseofulvin Microsize:

Some medical conditions may interact with Griseofulvin Microsize. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have diabetes, liver disease, lupus, or numbness of the hands or feet

Some MEDICINES MAY INTERACT with Griseofulvin Microsize. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital) because they may decrease Griseofulvin Microsize’s effectiveness
Anticoagulants (eg, warfarin), cyclosporine, or oral contraceptives (birth control pills) because their effectiveness may be decreased by Griseofulvin Microsize

This may not be a complete list of all interactions that may occur. Ask your health care provider if Griseofulvin Microsize may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Griseofulvin Microsize:

Use Griseofulvin Microsize as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Griseofulvin Microsize by mouth with or without food.
Shake well before each use.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
To clear up your infection completely, use Griseofulvin Microsize for the full course of treatment. Keep using it even if you feel better in a few days.
If you miss a dose of Griseofulvin Microsize, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Griseofulvin Microsize.

Important safety information:

Griseofulvin Microsize may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Griseofulvin Microsize with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Be sure to use Griseofulvin Microsize for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
Do not drink alcohol while you are taking Griseofulvin Microsize.
Griseofulvin Microsize may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Griseofulvin Microsize. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
It is important to practice good hygiene during and after use to prevent reinfection.
Hormonal birth control (eg, birth control pills) may not work as well while you are using Griseofulvin Microsize. To prevent pregnancy, use an extra form of birth control (eg, condoms).
Use an effective form of birth control for 6 months after using Griseofulvin Microsize.
Lab tests, including complete blood cell counts, liver function, and kidney function, may be performed while you use Griseofulvin Microsize. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Griseofulvin Microsize should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Griseofulvin Microsize if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. If you are or will be breast-feeding while you use Griseofulvin Microsize, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Griseofulvin Microsize:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; difficulty sleeping; dizziness; fatigue; headache; nausea; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; numbness of tingling of the hands or feet; white patches in the mouth.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Griseofulvin Microsize:

Store Griseofulvin Microsize at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Griseofulvin Microsize out of the reach of children and away from pets.

General information:

If you have any questions about Griseofulvin Microsize, please talk with your doctor, pharmacist, or other health care provider.
Griseofulvin Microsize is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Griseofulvin Microsize. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

G,Med-facts

Comments (0)

Griseofulvin Ultramicrosize Tablets

30/06/10

Generic Name: Griseofulvin (GRIS-ee-oh-FUL-vin)
Brand Name: Gris-PEG

Griseofulvin Ultramicrosize Tablets are used for:

Treating ringworm infections of the skin, hair, and nails. It is also used to treat athlete’s foot and “barber’s itch.” It may also be used for other conditions as determined by your doctor.

Griseofulvin Ultramicrosize Tablets are an antifungal agent. It works by making the skin more resistant to fungal growth.

Do NOT use Griseofulvin Ultramicrosize Tablets if:

you are allergic to any ingredient in Griseofulvin Ultramicrosize Tablets
you have liver failure or a blood disease (eg, porphyria)
you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Griseofulvin Ultramicrosize Tablets:

Some medical conditions may interact with Griseofulvin Ultramicrosize Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have liver disease or lupus

Some MEDICINES MAY INTERACT with Griseofulvin Ultramicrosize Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital) because they may decrease Griseofulvin Ultramicrosize Tablets’s effectiveness
Anticoagulants (eg, warfarin) or oral contraceptives (birth control pills) because their effectiveness may be decreased by Griseofulvin Ultramicrosize Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Griseofulvin Ultramicrosize Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Griseofulvin Ultramicrosize Tablets:

Use Griseofulvin Ultramicrosize Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Griseofulvin Ultramicrosize Tablets by mouth with or without food.
Swallow Griseofulvin Ultramicrosize Tablets whole.
You may also crush Griseofulvin Ultramicrosize Tablets and sprinkle it onto 1 tablespoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away without chewing.
To clear up your infection completely, take Griseofulvin Ultramicrosize Tablets for the full course of treatment. Keep taking it even if you feel better in a few days.
If you miss a dose of Griseofulvin Ultramicrosize Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Griseofulvin Ultramicrosize Tablets.

Important safety information:

Griseofulvin Ultramicrosize Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Griseofulvin Ultramicrosize Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Be sure to use Griseofulvin Ultramicrosize Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
Do not drink alcohol while you are taking Griseofulvin Ultramicrosize Tablets.
Griseofulvin Ultramicrosize Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Griseofulvin Ultramicrosize Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
It is important to practice good hygiene during and after use to prevent reinfection.
Hormonal birth control (eg, birth control pills) may not work as well while you are using Griseofulvin Ultramicrosize Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).
Griseofulvin Ultramicrosize Tablets should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: Do not use Griseofulvin Ultramicrosize Tablets if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Griseofulvin Ultramicrosize Tablets are found in breast milk. If you are or will be breast-feeding while you use Griseofulvin Ultramicrosize Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Griseofulvin Ultramicrosize Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; fever; flu-like symptoms (eg, headache, joint pain); sore throat; white patches in the mouth.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Griseofulvin Ultramicrosize Tablets:

Store Griseofulvin Ultramicrosize Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Griseofulvin Ultramicrosize Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Griseofulvin Ultramicrosize Tablets, please talk with your doctor, pharmacist, or other health care provider.
Griseofulvin Ultramicrosize Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Griseofulvin Ultramicrosize Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

G,Med-facts

Comments (0)

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Important safety information:

Possible side effects of Guaifenesin Sustained-Release Tablets:

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Griseofulvin Microsize Tablets are used for:

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Before using Griseofulvin Microsize Tablets:

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If OVERDOSE is suspected:

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