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Lotrimin Jock Itch Powder

30/06/10

Generic Name: clotrimazole topical (kloe TRIM a zole)
Brand Names: Desenex AF Prescription Strength, Fungoid Solution, Lotrimin, Lotrimin Jock Itch Powder, Mycelex, Mycelex OTC

What is Lotrimin Jock Itch Powder (clotrimazole topical)?

Clotrimazole topical is an antifungal medication. Clotrimazole topical prevents fungus from growing on your skin.

Clotrimazole topical is used to treat skin infections such as athlete’s foot, jock itch, ringworm, and yeast infections.

Clotrimazole topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Lotrimin Jock Itch Powder (clotrimazole topical)?

Use this medication for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed.

Do not use bandages or dressings that do not allow air to circulate to the affected area (occlusive dressings) unless otherwise directed by your doctor. Wear loose-fitting clothing (preferably cotton).

Avoid getting this medication in your eyes, nose, or mouth.

Who should not use Lotrimin Jock Itch Powder (clotrimazole topical)?

Do not use clotrimazole topical if you have had an allergic reaction to it in the past.

Clotrimazole topical is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not use clotrimazole topical without first talking to your doctor if you are pregnant. It is not known whether clotrimazole passes into breast milk. Do not use clotrimazole topical without first talking to your doctor if you are breast-feeding a baby.

How should I use Lotrimin Jock Itch Powder (clotrimazole topical)?

Use clotrimazole topical exactly as directed by your doctor or follow the directions that accompany the package. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before and after using this medication, unless you are using it to treat a hand infection.

Clean and dry the affected area. Apply a small amount of the cream (usually twice daily) for 2 to 4 weeks.

Do not take this medication by mouth.

If the infection does not clear up in 4 weeks, or if it appears to get worse, see your doctor.

Do not use bandages or dressings that do not allow air circulation over the affected area (occlusive dressings) unless otherwise directed by your doctor. A light cotton-gauze dressing may be used to protect clothing.

Avoid getting this medication in your eyes, nose, or mouth. Store clotrimazole topical at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the dose you missed and apply only the regular amount of clotrimazole topical. Do not use a double dose unless otherwise directed by your doctor.

What happens if I overdose?

An overdose of clotrimazole topical is unlikely to occur. If you do suspect that a much larger than normal dose has been used, or that clotrimazole topical has been ingested, contact an emergency room or a poison control center.

What should I avoid while using Lotrimin Jock Itch Powder (clotrimazole topical)?

Avoid wearing tight-fitting, synthetic clothing that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.

Lotrimin Jock Itch Powder (clotrimazole topical) side effects

Serious side effects of clotrimazole topical use are not expected. Stop using clotrimazole topical and see your doctor if you experience unusual or severe blistering, itching, redness, peeling, dryness, swelling, or irritation of the skin.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Lotrimin Jock Itch Powder (clotrimazole topical)?

Avoid using other topicals at the same time unless your doctor approves. Other skin medications may affect the absorption or effectiveness of clotrimazole topical.

Drugs other than those listed here may also interact with clotrimazole topical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has additional information about clotrimazole topical written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Lotrisone

30/06/10

Generic Name: betamethasone and clotrimazole topical (bay ta METH a sone and kloe TRIM a zole)
Brand Names: Lotrisone

What is betamethasone and clotrimazole topical?

Clotrimazole is an antifungal antibiotic that treats or prevents infection caused by fungus.

Betamethasone is a topical steroid that reduces itching, swelling, and redness of the skin.

The combination of betamethasone and clotrimazole topical is used to treat fungal skin infections such as athlete’s foot, jock itch, and ringworm.

Betamethasone and clotrimazole topical may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about betamethasone and clotrimazole topical?

Do not cover treated skin areas with a bandage or tight clothing, unless your doctor has told you to. Do not use this medication on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Never use betamethasone and clotrimazole to treat diaper rash. It may take up to 1 or 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your groin symptoms do not improve after 1 week, or if your foot symptoms do not improve after 2 weeks of treatment.

What should I discuss with my healthcare provider before using betamethasone and clotrimazole topical?

Do not use this medication if you have ever had an allergic reaction to:

betamethasone (such as Betaderm, Diprolene, Luxiq, Taclonex, Uticort, Valisone);
clotrimazole (such as Desenex, Lotrimin, Mycelex);
other topical steroid medications such as alclometasone (Aclovate), clobetasol (Olux, Temovate), desonide (Desowen), desoximetasone (Topicort), diflorasone (Florone, Psorcon), fluocinolone (Capex, Dermotic, Fluonid, Fluorosyn, Synalar), fluocinonide (Dermacin, Lidex), fluticasone (Cutivate), halcinonide (Halog), halobetasol (Ultravate), mometasone (Elocon), triamcinolone (Aristocort, Kenalog); or
other topical antibiotics such as econazole (Spectazole), ketoconazole (Kuric, Nizoral), miconazole (Cruex, Desenex, Fungoid, Lotrimin, Micatin, Monistat), sertaconazole (Ertaczo), or sulconazole (Exelderm).

Before using betamethasone topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection. You may not be able to use this medication, or you may need a dose adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether betamethasone and clotrimazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child younger than 17 years old. Children are more likely to absorb the steroid through the skin. Never use betamethasone and clotrimazole to treat diaper rash.

How should I use betamethasone and clotrimazole topical?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after applying this medicine. Shake the lotion form of this medication well just before you use it.

Apply a thin layer of the medication and rub it in completely.

Do not cover treated skin areas with a bandage or tight clothing, unless your doctor has told you to.

After applying this medication, allow your skin to dry completely before dressing. Wear loose-fitting clothing while you are treating jock itch. If you are treating athlete’s foot, wear clean cotton socks and keep your feet as dry as possible.

Do not use betamethasone and clotrimazole for longer than 2 weeks for jock itch or 4 weeks for athlete’s foot, unless your doctor has told you to. It may take up to 1 or 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your groin symptoms do not improve after 1 week, or if your foot symptoms do not improve after 2 weeks of treatment. Store this medicine at room temperature away from moisture and heat. Keep the tube or bottle capped and tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of betamethasone and clotrimazole applied to the skin is not expected to produce life-threatening symptoms.

What should I avoid while using betamethasone and clotrimazole topical?

Avoid getting this medication in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use betamethasone and clotrimazole topical on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid wearing tight-fitting clothing that doesn’t allow air circulation. Until the infection is healed, wear clothing that is made of natural fibers such as cotton.

Betamethasone and clotrimazole topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these signs that you may be absorbing betamethasone topical through your skin or gums:

swelling, redness, or any signs of new infection;
severe burning or stinging of treated skin;
weight gain, rounding of the face;
increased thirst or hunger, urinating more than usual; or
anxiety, depressed mood.

Less serious side effects may include:

mild skin itching or irritation;
dry skin;
changes in skin color;
increased acne; or
scarring or thinning of the skin.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect betamethasone and clotrimazole topical?

It is not likely that other drugs you take orally or inject will have an effect on topically applied betamethasone and clotrimazole. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about betamethasone and clotrimazole topical.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,L

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Lotrimin Cream

30/06/10

Generic Name: Clotrimazole (kloe-TRIM-uh-zole)
Brand Name: Examples include Lotrimin and Mycelex

Lotrimin Cream is used for:

Treating athlete’s foot, jock itch, and ringworm. It may also be used for other conditions as determined by your doctor.

Lotrimin Cream is an antifungal agent. It kills sensitive fungi by binding to the fungal cell membrane and weakening it. This allows the cell contents to leak out and results in the death of the fungus.

Do NOT use Lotrimin Cream if:

you are allergic to any ingredient in Lotrimin Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lotrimin Cream:

Some medical conditions may interact with Lotrimin Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Lotrimin Cream. Because little, if any, of Lotrimin Cream is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Lotrimin Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lotrimin Cream:

Use Lotrimin Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Lotrimin Cream is for topical use on the skin only.
Clean the affected area with soap and water and dry thoroughly.
Apply a thin layer of medicine to the affected area. Rub it in gently. Do not cover unless directed to by your doctor.
Wash your hands immediately after using Lotrimin Cream, unless your hands are part of the treated area.
To clear up your infection completely, use Lotrimin Cream for the full course of treatment. Keep using it even if you feel better in a few days.
If you miss a dose of Lotrimin Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Lotrimin Cream.

Important safety information:

Lotrimin Cream is for external use only. If you get Lotrimin Cream in your eyes, immediately flush them with cool tap water.
Be sure to use Lotrimin Cream for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lotrimin Cream while you are pregnant. It is not known if Lotrimin Cream is found in breast milk. If you are or will be breast-feeding while you use Lotrimin Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lotrimin Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); reddening, blistering, peeling, itching, or burning of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Lotrimin Cream may be harmful if swallowed.

Proper storage of Lotrimin Cream:

Store Lotrimin Cream at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lotrimin Cream out of the reach of children and away from pets.

General information:

If you have any questions about Lotrimin Cream, please talk with your doctor, pharmacist, or other health care provider.
Lotrimin Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Lotrimin Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

L,Med-facts

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Lotrimin AF

30/06/10

Generic Name: clotrimazole (Topical route)

kloe-TRIM-a-zole

Commonly used brand name(s):

In the U.S.

Clotrim Antifungal
Cruex Prescription Strength
Lotrimin
Lotrimin AF
Mycelex

In Canada

Canesten
Clotrimaderm
Desenex
Myclo-Derm
Neo-Zol

Available Dosage Forms:

Lotion
Solution
Cream

Therapeutic Class: Antifungal

Chemical Class: Imidazole

Uses For Lotrimin AF

Clotrimazole topical preparations are used to treat fungus infections on the skin.

This medicine is available both over-the-counter (OTC) and with your doctor’s prescription.

Before Using Lotrimin AF

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of topical clotrimazole in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Dihydroergotamine
Ergoloid Mesylates
Ergonovine
Ergotamine
Methylergonovine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Fentanyl
Tacrolimus
Trimetrexate

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of clotrimazole

This section provides information on the proper use of a number of products that contain clotrimazole. It may not be specific to Lotrimin AF. Please read with care.

Apply enough clotrimazole to cover the affected and surrounding skin areas, and rub in gently.

Keep this medicine away from the eyes.

When clotrimazole is used to treat certain types of fungus infections of the skin, an occlusive dressing (airtight covering, such as kitchen plastic wrap) should not be applied over the medicine. To do so may cause irritation of the skin. Do not apply an occlusive dressing over this medicine unless you have been directed to do so by your doctor.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a few days. Since fungus infections may be very slow to clear up, you may have to continue using this medicine every day for several weeks or more. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage forms (cream, lotion, and solution):
- Fungal infections (treatment):
  - Adults and children—Use two times a day, morning and evening.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Lotrimin AF

If your skin problem does not improve within 4 weeks, or if it becomes worse, check with your doctor.

Lotrimin AF Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Skin rash, hives, blistering, burning, itching, peeling, redness, stinging, swelling, or other sign of skin irritation not present before use of this medicine

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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Lotrimin AF Lotion

30/06/10

Generic Name: Clotrimazole (kloe-TRIM-uh-zole)
Brand Name: Lotrimin AF

Lotrimin AF Lotion is used for:

Treating athlete’s foot, jock itch, and ringworm. It may also be used for other conditions as determined by your doctor.

Lotrimin AF Lotion is an antifungal agent. It kills sensitive fungi by binding to the fungal cell membrane and weakening it. This allows the cell contents to leak out and results in the death of the fungus.

Do NOT use Lotrimin AF Lotion if:

you are allergic to any ingredient in Lotrimin AF Lotion

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lotrimin AF Lotion:

Some medical conditions may interact with Lotrimin AF Lotion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Lotrimin AF Lotion. Because little, if any, of Lotrimin AF Lotion is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Lotrimin AF Lotion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lotrimin AF Lotion:

Use Lotrimin AF Lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Lotrimin AF Lotion is for topical use on the skin only.
Clean the affected area with soap and water and dry thoroughly.
Shake well before each use.
Apply a thin layer of medicine to the affected area. Rub it in gently. Do not cover unless directed to by your doctor.
Wash your hands immediately after using Lotrimin AF Lotion, unless your hands are part of the treated area.
To clear up your infection completely, use Lotrimin AF Lotion for the full course of treatment. Keep using it even if you feel better in a few days. Do not miss any doses.
If you miss a dose of Lotrimin AF Lotion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Lotrimin AF Lotion.

Important safety information:

Lotrimin AF Lotion is for external use only. If you get Lotrimin AF Lotion in your eyes, immediately flush them with cool tap water.
Be sure to use Lotrimin AF Lotion for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lotrimin AF Lotion while you are pregnant. It is not known if Lotrimin AF Lotion is found in breast milk. If you are or will be breast-feeding while you use Lotrimin AF Lotion, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lotrimin AF Lotion:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); reddening, blistering, peeling, itching, or burning of the skin.

If OVERDOSE is suspected:

Proper storage of Lotrimin AF Lotion:

Store Lotrimin AF Lotion at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lotrimin AF Lotion out of the reach of children and away from pets.

General information:

If you have any questions about Lotrimin AF Lotion, please talk with your doctor, pharmacist, or other health care provider.
Lotrimin AF Lotion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Lotrimin AF Lotion. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

L,Med-facts

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Lotrimin AF Solution

30/06/10

Generic Name: Clotrimazole (kloe-TRIM-a-zole)
Brand Name: Lotrimin AF

Lotrimin AF Solution is used for:

Treating athlete’s foot, jock itch, and ringworm. It may also be used for other conditions as determined by your doctor.

Lotrimin AF Solution is an antifungal agent. It kills sensitive fungi by binding to and weakening the fungal cell membrane.

Do NOT use Lotrimin AF Solution if:

you are allergic to any ingredient in Lotrimin AF Solution

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lotrimin AF Solution:

Some medical conditions may interact with Lotrimin AF Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Lotrimin AF Solution. Because little, if any, of Lotrimin AF Solution is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Lotrimin AF Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lotrimin AF Solution:

Use Lotrimin AF Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Lotrimin AF Solution is for topical use on the skin only.
Clean the affected area with soap and water and dry thoroughly.
Apply a thin layer of medicine to the affected area. Rub it in gently. Do not cover unless directed to by your doctor.
Wash your hands immediately after using Lotrimin AF Solution, unless your hands are part of the treated area.
To clear up your infection completely, use Lotrimin AF Solution for the full course of treatment. Keep using it even if you feel better in a few days.
If you miss a dose of Lotrimin AF Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Lotrimin AF Solution.

Important safety information:

Lotrimin AF Solution is for external use only. If you get Lotrimin AF Solution in your eyes, immediately flush them with cool tap water.
Be sure to use Lotrimin AF Solution for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lotrimin AF Solution while you are pregnant. It is not known if Lotrimin AF Solution is found in breast milk. If you are or will be breast-feeding while you use Lotrimin AF Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Lotrimin AF Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); reddening, blistering, peeling, itching, or burning of the skin.

If OVERDOSE is suspected:

Proper storage of Lotrimin AF Solution:

Store Lotrimin AF Solution at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lotrimin AF Solution out of the reach of children and away from pets.

General information:

If you have any questions about Lotrimin AF Solution, please talk with your doctor, pharmacist, or other health care provider.
Lotrimin AF Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Lotrimin AF Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

L,Med-facts

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Lotriderm

30/06/10

Generic Name: betamethasone and clotrimazole (Topical route)

kloe-TRIM-a-zole, bay-ta-METH-a-sone dye-PROE-pee-oh-nate

Commonly used brand name(s):

In the U.S.

Lotrisone

In Canada

Lotriderm
Pms-Clotrimazole And Betamethasone

Available Dosage Forms:

Cream
Lotion

Therapeutic Class: Anti-Infective/Anti-Inflammatory Combination

Pharmacologic Class: Betamethasone

Chemical Class: Imidazole

Uses For Lotriderm

Clotrimazole and betamethasone combination is used to treat fungus infections. Clotrimazole works by killing the fungus or preventing its growth. Betamethasone, a corticosteroid (cortisone-like medicine or steroid), is used to help relieve redness, swelling, itching, and other discomfort of fungus infections.

Clotrimazole and betamethasone cream or lotion is applied to the skin to treat:

athlete’s foot (ringworm of the foot; tinea pedis);
jock itch (ringworm of the groin; tinea cruris); and
ringworm of the body (tinea corporis) .

This medicine may also be used for other fungus infections of the skin as determined by your doctor.

This medicine is available only with your doctor’s prescription.

Before Using Lotriderm

Allergies

Pediatric

Appropriate studies performed to date have not demonstrated pediatrics-specific problems that would limit the usefulness of clotrimazole and betamethasone combination in teenagers 17 years of age and older. Safety and efficacy have not been established in children and teenagers below 17 years of age .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of clotrimazole and betamethasone combination in the elderly. However, elderly patients are more likely to have a thinning skin, which may require caution in patients receiving clotrimazole and betamethasone .

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Dihydroergotamine
Ergoloid Mesylates
Ergonovine
Ergotamine
Methylergonovine
Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aldesleukin
Bupropion
Quetiapine

Alatrofloxacin
Alcuronium
Aspirin
Atracurium
Balofloxacin
Cinoxacin
Ciprofloxacin
Clinafloxacin
Enoxacin
Ethinyl Estradiol
Etonogestrel
Fentanyl
Fleroxacin
Flumequine
Fosphenytoin
Gallamine
Gemifloxacin
Grepafloxacin
Hexafluorenium
Itraconazole
Levofloxacin
Licorice
Lomefloxacin
Mestranol
Metocurine
Moxifloxacin
Norelgestromin
Norethindrone
Norfloxacin
Norgestrel
Ofloxacin
Pefloxacin
Phenobarbital
Phenytoin
Primidone
Prulifloxacin
Rifampin
Rifapentine
Rosoxacin
Rufloxacin
Saiboku-To
Sparfloxacin
Tacrolimus
Temafloxacin
Tosufloxacin
Trimetrexate
Trovafloxacin Mesylate

Interactions with Food/Tobacco/Alcohol

Proper Use of betamethasone and clotrimazole

This section provides information on the proper use of a number of products that contain betamethasone and clotrimazole. It may not be specific to Lotriderm. Please read with care.

Before applying this medicine, wash the affected area with soap and water, and dry thoroughly.

Do not use this medicine in the eyes.

To use:

Check with your doctor before using this medicine on any other skin problems. It should not be used on bacterial or virus infections or on diaper rash. Also, it should only be used on certain kinds of fungus infections of the skin.
Apply a thin layer of this medicine to the affected area(s) and surrounding skin. Rub in gently and thoroughly.

The use of any kind of occlusive dressing (airtight covering, such as kitchen plastic wrap) over this medicine may increase absorption of the medicine and the chance of irritation and other side effects. Therefore, do not bandage, wrap, or apply any occlusive dressing over this medicine unless directed by your doctor. Also, wear loose-fitting clothing when using this medicine on the groin area. When using this medicine on the diaper area of children, avoid tight-fitting diapers and plastic pants.

To help clear up your skin infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered. To do so may increase absorption through your skin and the chance of side effects. In addition, too much use, especially on thin skin areas (for example, face, armpits, genitals [sex organs], between the toes, groin), may result in thinning of the skin and in stretch marks.

Dosing

For topical cream or lotion dosage form:
- For jock itch (ringworm of the groin; tinea cruris) or ringworm of the body (tinea corporis):
  - Adults and teenagers 17 years of age and over—Apply to the affected skin and surrounding area(s) two times a day, morning and evening, for 2 weeks.
  - Children and teenagers up to 16 years of age—Use and dose must be determined by your doctor .
- For athlete’s foot (ringworm of the foot; tinea pedis):
  - Adults and teenagers 17 years of age and over—Apply to the affected skin and surrounding area(s) two times a day, morning and evening, for 4 weeks.
  - Children and teenagers up to 16 years of age—Use and dose must be determined by your doctor .

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Lotriderm

If your skin infection does not improve within 1 week for jock itch or ringworm of the body and 2 weeks for athlete’s foot, or if it becomes worse, check with your doctor. Redness and itching should get better within 3 to 5 days of therapy.

To help clear up your skin infection completely and to help make sure it does not return, the following good health habits are important:

For patients using this medicine for athlete’s foot:
- Carefully dry the feet, especially between the toes, after bathing.
- Avoid wearing socks made from wool or synthetic materials (for example, rayon or nylon). Instead, wear clean, cotton socks and change them daily or more often if your feet sweat freely.
- Wear well-ventilated shoes (for example, shoes with holes) or sandals.
- Use a bland, absorbent powder (for example, talcum powder) or an antifungal powder freely between the toes, on the feet, and in socks and shoes once or twice a day. Be sure to use the powder after clotrimazole and betamethasone cream has been applied and has disappeared into the skin. Do not use the powder as the only treatment for your fungus infection.
These measures will help keep the feet cool and dry.
For patients using this medicine for jock itch:
- Carefully dry the groin area after bathing.
- Avoid wearing underwear that is tight-fitting or made from synthetic materials (for example, rayon or nylon). Instead, wear loose-fitting, cotton underwear.
- Use a bland, absorbent powder (for example, talcum powder) or an antifungal powder freely once or twice a day. Be sure to use the powder after clotrimazole and betamethasone cream has been applied and has disappeared into the skin. Do not use the powder as the only treatment for your fungus infection.
These measures will help reduce chafing and irritation and will also help keep the groin area cool and dry.
For patients using this medicine for ringworm of the body:
- Carefully dry yourself after bathing.
- Avoid too much heat and humidity if possible. Try to keep moisture from building up on affected areas of the body.
- Wear well-ventilated clothing.
- Use a bland, absorbent powder (for example, talcum powder) or an antifungal powder freely once or twice a day. Be sure to use the powder after clotrimazole and betamethasone cream has been applied and has disappeared into the skin. Do not use the powder as the only treatment for your fungus infection.
These measures will help keep the affected areas cool and dry.

If you have any questions about this, check with your health care professional.

For diabetic patients:

Rarely, the corticosteroid in this medicine may cause higher blood and urine sugar levels. This is more likely to occur if you have severe diabetes and are using large amounts of this medicine. Check with your doctor before changing your diet or the dosage of your diabetes medicine.

Lotriderm Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blistering, burning, itching, peeling, dryness, redness, or other signs of skin irritation not present before use of this medicine
burning, crawling, itching, numbness, prickling, “pins and needles” , or tingling feelings
hives

Rare

Cough or hoarseness
fever or chills
lower back or side pain
painful or difficult urination
rash
stinging
swelling

Incidence not known

Abdominal pain
backache
blurred vision
dry mouth
facial hair growth in females
flushed, dry skin
fractures
fruit-like breath odor
full or round face, neck, or trunk
increased hunger, thirst, or urination
irritability
loss of sexual desire or ability
menstrual irregularities
muscle wasting
nausea
sugar in the urine
sweating
troubled breathing
unexplained weight loss
unusual tiredness or weakness
vomiting

Check with your doctor as soon as possible if any of the following side effects occur:

Incidence not known

Acne or oily skin
increased hair growth, especially on the face and body
increased loss of hair, especially on the scalp
pus in the hair follicles
reddish purple lines on arms, face, legs, trunk, or groin
redness and scaling around the mouth
softening of the skin
thinning of skin with easy bruising
white spots

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,L

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Lotrimin

30/06/10

Generic Name: clotrimazole topical (kloe TRIM a zole)
Brand Names: Desenex AF Prescription Strength, Fungoid Solution, Lotrimin, Lotrimin Jock Itch Powder, Mycelex, Mycelex OTC

What is Lotrimin (clotrimazole topical)?

Clotrimazole topical is an antifungal medication. Clotrimazole topical prevents fungus from growing on your skin.

Clotrimazole topical is used to treat skin infections such as athlete’s foot, jock itch, ringworm, and yeast infections.

Clotrimazole topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Lotrimin (clotrimazole topical)?

Avoid getting this medication in your eyes, nose, or mouth.

Who should not use Lotrimin (clotrimazole topical)?

Do not use clotrimazole topical if you have had an allergic reaction to it in the past.

How should I use Lotrimin (clotrimazole topical)?

Wash your hands before and after using this medication, unless you are using it to treat a hand infection.

Clean and dry the affected area. Apply a small amount of the cream (usually twice daily) for 2 to 4 weeks.

Do not take this medication by mouth.

If the infection does not clear up in 4 weeks, or if it appears to get worse, see your doctor.

Avoid getting this medication in your eyes, nose, or mouth. Store clotrimazole topical at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using Lotrimin (clotrimazole topical)?

Avoid wearing tight-fitting, synthetic clothing that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.

Lotrimin (clotrimazole topical) side effects

What other drugs will affect Lotrimin (clotrimazole topical)?

Avoid using other topicals at the same time unless your doctor approves. Other skin medications may affect the absorption or effectiveness of clotrimazole topical.

Drugs other than those listed here may also interact with clotrimazole topical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines.

Where can I get more information?

Your pharmacist has additional information about clotrimazole topical written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,L

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loteprednol etabonate and tobramycin (Ophthalmic route)

30/06/10

loe-te-PRED-nol et-a-BOE-nate, toe-bra-MYE-sin

Commonly used brand name(s):

In the U.S.

Zylet

Available Dosage Forms:

Suspension

Therapeutic Class: Aminoglycoside/Corticosteroid Combination

Pharmacologic Class: Loteprednol

Chemical Class: Aminoglycoside

Uses For loteprednol etabonate and tobramycin

Loteprednol and tobramycin is a combination of an antibiotic and a corticosteroid. It is used in the eye to prevent permanent damage, which may occur with certain eye problems.

loteprednol etabonate and tobramycin is available only with your doctor’s prescription.

Before Using loteprednol etabonate and tobramycin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For loteprednol etabonate and tobramycin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to loteprednol etabonate and tobramycin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on loteprednol etabonate and tobramycin have been done only in adult patients, and there is no specific information comparing use of loteprednol and tobramycin in children with use in other age groups.

Geriatric

loteprednol etabonate and tobramycin has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using loteprednol etabonate and tobramycin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alcuronium
Atracurium
Cidofovir
Cisatracurium
Decamethonium
Doxacurium
Ethacrynic Acid
Fazadinium
Furosemide
Gallamine
Hexafluorenium
Lysine
Metocurine
Mivacurium
Pancuronium
Pipecuronium
Rapacuronium
Rocuronium
Succinylcholine
Tacrolimus
Tubocurarine
Vancomycin
Vecuronium

Using loteprednol etabonate and tobramycin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Cisplatin
Cyclosporine

Interactions with Food/Tobacco/Alcohol

Proper Use of loteprednol etabonate and tobramycin

Shake the container very well before applying the eye drops.

Using only if the imprinted neckband is intact.

Do not wear soft contact lenses while you are using loteprednol etabonate and tobramycin..

Decrease use gradually as symptoms improve.

To help clear up your eye infection completely, keep using loteprednol and tobramycin for the full time of treatment, even if your symptoms have disappeared.

To use:

First, wash your hands. Tilt your head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
If you think you did not get the drop of medicine into your eye properly, use another drop.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

Dosing

The dose of loteprednol etabonate and tobramycin will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of loteprednol etabonate and tobramycin. If your dose is different, do not change it unless your doctor tells you to do so.

For ophthalmic suspension dosage form (eye drops):
- For eye disorders:
  - Adults—Use one or two drops into the affected eye every four to six hours. Your doctor may have you use the drops more frequently during the first day or two and will probably have you space the doses further apart as the eye gets better
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of loteprednol etabonate and tobramycin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store upright.

Precautions While Using loteprednol etabonate and tobramycin

If you will be using loteprednol etabonate and tobramycin for more than few weeks, an ophthalmologist (eye doctor) should examine your eyes at regular visits to make sure it does not cause unwanted effects.

If your eye infection does not improve or if your condition becomes worse, check with your doctor.

loteprednol etabonate and tobramycin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Increased intraocular pressure
painful irritation of the clear front part of the eye

Less common

Blurred vision or blue-green halos seen around objects
blurred vision or other changes in vision
decreased vision
discharge from the eye
dry eyes
eyelid burning, redness, itching, pain, or tenderness
fast heartbeat
fever
hives
hoarseness
irritation and swelling of the eye
itching
joint pain
lid itching and swelling
pain in eye
rash
redness of skin
redness of eyelid
sensitivity of eyes to light
shortness of breath
stiffness or swelling
swelling of eyelids, face, lips, hands, or feet
tightness in chest
troubled breathing or swallowing
wheezing

Incidence not known

Redness of eye
tearing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning
dry eyes
headache
increased sensitivity of eyes to light
itching
stinging

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,L

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loteprednol ophthalmic

30/06/10

Generic Name: loteprednol ophthalmic (lo te PRED nol off THAL mik)
Brand Names: Alrex, Lotemax

What is loteprednol ophthalmic?

Loteprednol is in a group of drugs called corticosteroids. It prevents the release of substances in the body that cause inflammation.

Loteprednol ophthalmic (for the eye) is used to treat eye swelling caused by surgery, infection, allergies, and other conditions.

Loteprednol ophthalmic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about loteprednol ophthalmic?

Do not use this medication while you are wearing contact lenses. This medication may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using loteprednol before putting your contact lenses in. Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. Stop using loteprednol and call your doctor at once if you have signs of a new eye infection such as swelling, redness, irritation, or drainage, or if you have problems with your vision, or severe pain, burning, or stinging when you use the eye drops. Call your doctor if your symptoms do not improve after 2 days of treatment.

What should I discuss with my healthcare provider before using loteprednol ophthalmic?

You should not use this medication if you are allergic to loteprednol, or if you have any type of fungal, viral, or bacterial infection of your eye.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

glaucoma;
cataracts (or if you have recently had cataract surgery); or
herpes infection of your eye.

FDA pregnancy category C. It is not known whether loteprednol is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether loteprednol ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use loteprednol ophthalmic?

Do not use this medication for longer than 2 weeks unless your doctor tells you to.

Wash your hands before using the eye drops. Shake the eye drops well just before each use.

To apply the eye drops:

Tilt your head back slightly and pull down on the lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper. Squeeze out a drop and close your eye.
Gently press your finger to the inside corner of the eye (near the nose) for about 1 minute to keep the liquid from draining into your tear duct.

Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Call your doctor if your symptoms do not improve after 2 days of treatment.

To be sure loteprednol is not causing harmful effects, your vision may need to be checked after using the medication for 10 days or longer. Do not miss any scheduled visits to your doctor.

Store loteprednol ophthalmic with the cap on at room temperature, away from moisture and heat. Do not use the eye drops if the liquid changes colors or has particles in it. Call your doctor for a new prescription.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of loteprednol ophthalmic is not likely to cause life-threatening symptoms.

What should I avoid while using loteprednol ophthalmic?

Avoid using other medications in your eyes during treatment with loteprednol ophthalmic unless your doctor has told you to.

Loteprednol ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using loteprednol and call your doctor at once if you have any of these serious side effects:

signs of a new eye infection such as swelling, redness, irritation, or drainage;
problems with your vision; or
severe pain, burning or stinging when using the eye drops.

Less serious side effects may include:

minor burning when using the eye drops;
dry, red, itchy, or watery eyes;
feeling that something is in your eye;
being more sensitive to light;
headache; or
runny nose, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.