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muromonab-cd3 (Intravenous route)

30/06/10

mue-roe-MOE-nab-CD3

Intravenous routeSolution

Only physicians experienced in immunosuppressive therapy and management of solid organ transplant patients should use muromonab-CD3. Patients treated with muromonab-CD3 must be managed in a facility equipped and staffed for cardiopulmonary resuscitation and where the patient can be closely monitored for an appropriate period based on his or her health status.

Anaphylactic and anaphylactoid reactions may occur following administration of any dose or course of muromonab-CD3. In addition, serious, occasionally life-threatening or lethal, systemic, cardiovascular, and central nervous system reactions have been reported following administration of muromonab-CD3. These have included: pulmonary edema, especially in patients with volume overload; shock, cardiovascular collapse, cardiac or respiratory arrest, seizures, coma, cerebral edema, cerebral herniation, blindness, and paralysis. Fluid status should be carefully monitored prior to and during muromonab-CD3 administration. Pretreatment with methylprednisolone is recommended to minimize symptoms of Cytokine Release Syndrome .

Anaphylactic and anaphylactoid reactions may occur following administration of any dose. Serious, occasionally life-threatening or lethal, systemic, cardiovascular, and central nervous system reactions have been reported. These have included: pulmonary edema, especially in patients with volume overload; shock; cardiovascular collapse; cardiac or respiratory arrest; seizures; coma; cerebral edema; cerebral herniation; blindness; and paralysis. Monitor fluid status prior to and during treatment and premedicate with methylprednisolone to minimize symptoms of Cytokine Release Syndrome .

Commonly used brand name(s):

In the U.S.

Orthoclone OKT 3

Available Dosage Forms:

Solution

Therapeutic Class: Immunological Agent

Pharmacologic Class: Monoclonal Antibody

Uses For muromonab-cd3

Muromonab-CD3 is a monoclonal antibody. It is used to reduce the body’s natural immunity in patients who receive organ (for example, kidney) transplants.

When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ. Muromonab-CD3 works by preventing the white blood cells from doing this.

The effect of muromonab-CD3 on the white blood cells may also reduce the body’s ability to fight infections. Before you begin treatment, you and your doctor should talk about the good muromonab-cd3 will do as well as the risks of using it.

Muromonab-CD3 is to be administered only by or under the immediate supervision of your doctor.

Before Using muromonab-cd3

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For muromonab-cd3, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to muromonab-cd3 or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

There is no specific information comparing use of muromonab-CD3 in children with use in other age groups. However, children are more likely to get dehydrated from the diarrhea and vomiting that may be caused by muromonab-cd3.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of muromonab-CD3 in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of muromonab-cd3

Dosing

The dose of muromonab-cd3 will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of muromonab-cd3. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For injection dosage form:
- To prevent organ transplant rejection:
  - Adults—5 milligrams (mg) injected into a vein once a day.
  - Children less than 12 years of age—Dose is based on body weight and must be determined by your doctor.

Precautions While Using muromonab-cd3

It is very important that your doctor check your progress at regular visits to make sure that muromonab-cd3 is working properly and to check for unwanted effects.

While you are being treated with muromonab-CD3 and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor’s approval. Muromonab-CD3 may lower your body’s resistance. For some immunizations, there is a chance you might get the infection the immunization is meant to prevent. For other immunizations, it may be especially important to receive the immunization to prevent a disease. In addition, other persons living in your house should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have recently taken oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Treatment with muromonab-CD3 may also increase the chance of getting other infections. If you can, avoid people with colds or other infections. If you think you are getting a cold or other infection, check with your doctor.

muromonab-cd3 commonly causes chest pain, dizziness, fever and chills, shortness of breath, stomach upset, and trembling within a few hours after the first dose. These effects should be less after the second dose. However, check with your doctor or nurse immediately if you have chest pain, rapid or irregular heartbeat, shortness of breath or wheezing, or swelling of the face or throat after any dose.

muromonab-cd3 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Because of the way that muromonab-CD3 acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphomas and skin cancers. Discuss these possible effects with your doctor.

Although not all of the following side effects may occur, if they do occur, they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Chest pain
rapid or irregular heartbeat
shortness of breath or wheezing
swelling of face or throat

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Diarrhea
dizziness or faintness
fever and chills
general feeling of discomfort or illness
headache
muscle or joint pain
nausea and vomiting

Less common or rare

Confusion
black, tarry stools
blood in urine or stools
convulsions (seizures)
cough or hoarseness
hallucinations (seeing, hearing, or feeling things that are not there)
itching or tingling
loss of hearing or vision
lower back or side pain
painful or difficult urination
pinpoint red spots on skin
skin rash
sores, ulcers, or white spots on the lips or in the mouth
stiff neck
swollen or painful glands
tightness in the chest
trembling and shaking of hands
troubled breathing
unusual sensitivity of eyes to light
unusual bleeding or bruising
unusual tiredness
weakness

After you stop using muromonab-cd3, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Fever and chills

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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Murine Tears Plus Drops

30/06/10

Generic Name: Tetrahydrozoline (te-tra-hye-DROZ-oh-leen)
Brand Name: Examples include Eye Moisturizing Relief and Murine Tears

Murine Tears Plus Drops are used for:

Temporarily relieving redness, burning, and irritation caused by dry eyes. It may also be used for other conditions as determined by your doctor.

Murine Tears Plus Drops are an eye decongestant and lubricant. It works by constricting the blood vessels in the eye and coating the eye, which relieves redness and dryness.

Do NOT use Murine Tears Plus Drops if:

you are allergic to any ingredient in Murine Tears Plus Drops
you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Murine Tears Plus Drops:

Some medical conditions may interact with Murine Tears Plus Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have glaucoma, high blood pressure, diabetes, heart problems, or thyroid problems, or you are taking medicine for high blood pressure

Some MEDICINES MAY INTERACT with Murine Tears Plus Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

Tricyclic antidepressants (eg, amitriptyline) because they may decrease Murine Tears Plus Drops’s effectiveness
Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Murine Tears Plus Drops’s side effects, such as headache, fever, and high blood pressure
Bromocriptine or cocaine because their actions and side effects may be increased by Murine Tears Plus Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Murine Tears Plus Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Murine Tears Plus Drops:

Use Murine Tears Plus Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Murine Tears Plus Drops are for use in the eye only. Avoid contact with the nose, mouth, or other mucous membranes.
To use Murine Tears Plus Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
If you miss a dose of Murine Tears Plus Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Murine Tears Plus Drops.

Important safety information:

Remove contact lenses before using Murine Tears Plus Drops.
Do not use Murine Tears Plus Drops if it becomes cloudy or changes color.
Contact your doctor if you experience changes in your vision, eye pain, irritation, soreness, or continued redness, or if your condition does not improve after 3 days.
Use Murine Tears Plus Drops with caution in CHILDREN because they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Murine Tears Plus Drops, discuss with your doctor the benefits and risks of using Murine Tears Plus Drops during pregnancy. It is unknown if Murine Tears Plus Drops are excreted in breast milk. If you are or will be breast-feeding while you are using Murine Tears Plus Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Murine Tears Plus Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; minor stinging when the medicine is dropped into the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Murine Tears Plus Drops may be harmful if swallowed, especially in children.

Proper storage of Murine Tears Plus Drops:

Store Murine Tears Plus Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Murine Tears Plus Drops out of the reach of children and away from pets.

General information:

If you have any questions about Murine Tears Plus Drops, please talk with your doctor, pharmacist, or other health care provider.
Murine Tears Plus Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Murine Tears Plus Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

M,Med-facts

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Muro 128 Ointment

30/06/10

Generic Name: Sodium Chloride (SOE-dee-um KLOR-ide)
Brand Name: Muro 128

Muro 128 Ointment is used for:

Temporarily treating swelling of the cornea of the eye.

Muro 128 Ointment is a hypertonic salt solution. It works by drawing water out of the cornea, decreasing swelling.

Do NOT use Muro 128 Ointment if:

you are allergic to any ingredient in Muro 128 Ointment

Contact your doctor or health care provider right away if any of these apply to you.

Before using Muro 128 Ointment:

Some medical conditions may interact with Muro 128 Ointment. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Muro 128 Ointment. However, no specific interactions with Muro 128 Ointment are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Muro 128 Ointment may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Muro 128 Ointment:

Use Muro 128 Ointment as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use Muro 128 Ointment in the eye, first, wash your hands. Pull the lower eyelid away from your eye to form a pouch. Squeeze a thin strip of ointment into the pouch. After using the medicine, gently close your eyes for 1 to 2 minutes. Wash your hands to remove any medicine that may be on them. Wipe the applicator tip with a clean, dry tissue. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
Do not use Muro 128 Ointment if it changes color or is cloudy.
If you miss a dose of Muro 128 Ointment, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Muro 128 Ointment.

Important safety information:

Muro 128 Ointment may cause temporary blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous unless you can see clearly.
Muro 128 Ointment may be harmful if swallowed. If you may have taken Muro 128 Ointment by mouth, contact your local poison control center or emergency room immediately.
PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Muro 128 Ointment during pregnancy. If you are or will be breast-feeding while you are using Muro 128 Ointment, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Muro 128 Ointment:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild burning or irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued redness, burning, or irritation; eye pain; feeling that something is in the eye.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Muro 128 Ointment:

Store Muro 128 Ointment at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Muro 128 Ointment out of the reach of children and away from pets.

General information:

If you have any questions about Muro 128 Ointment, please talk with your doctor, pharmacist, or other health care provider.
Muro 128 Ointment is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Muro 128 Ointment. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

M,Med-facts

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Muro 128 Drops

30/06/10

Generic Name: Sodium Chloride (SOE-dee-um KLOR-ide)
Brand Name: Examples include Altachlore and Muro 128

Muro 128 Drops are used for:

Temporarily treating swelling of the cornea of the eye.

Muro 128 Drops are a hypertonic salt solution. It works by drawing water out of the cornea, decreasing swelling.

Do NOT use Muro 128 Drops if:

you are allergic to any ingredient in Muro 128 Drops

Contact your doctor or health care provider right away if any of these apply to you.

Before using Muro 128 Drops:

Some medical conditions may interact with Muro 128 Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Muro 128 Drops. However, no specific interactions with Muro 128 Drops are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Muro 128 Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Muro 128 Drops:

Use Muro 128 Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use Muro 128 Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
Do not use Muro 128 Drops if it changes color or is cloudy.
If you miss a dose of Muro 128 Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Muro 128 Drops.

Important safety information:

Muro 128 Drops may be harmful if swallowed. If you may have taken Muro 128 Drops by mouth, contact your local poison control center or emergency room immediately.
PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Muro 128 Drops during pregnancy. If you are or will be breast-feeding while you are using Muro 128 Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Muro 128 Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild burning or irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; continued redness, burning, or irritation; eye pain; feeling that something is in the eye.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Muro 128 Drops:

Store Muro 128 Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Muro 128 Drops out of the reach of children and away from pets.

General information:

If you have any questions about Muro 128 Drops, please talk with your doctor, pharmacist, or other health care provider.
Muro 128 Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Muro 128 Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

M,Med-facts

Comments (0)

Muro-128

30/06/10

Generic Name: sodium chloride (Ophthalmic route)

SOE-dee-um KLOR-ide

Commonly used brand name(s):

In the U.S.

AK-NaCl
Muro-128
OcuFresh
Sochlor

In Canada

Cordema
Eye Wash
In A Wink Daily Cleaner
In A Wink Neutralizing Rinse

Available Dosage Forms:

Solution
Ointment

Therapeutic Class: Osmotherapy Agent

Uses For Muro-128

Hypertonic sodium chloride solution for the eye is used to draw water out of a swollen cornea. The extra water in the cornea can cause your vision to be poor. You may also see halos or rings around point light sources. The cornea is the clear cover over the colored part of your eye.

This medicine is available only with your doctor’s prescription.

Before Using Muro-128

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of hypertonic sodium chloride in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of hypertonic sodium chloride in the elderly with use in other age groups.

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of sodium chloride

This section provides information on the proper use of a number of products that contain sodium chloride. It may not be specific to Muro-128. Please read with care.

To use:

The bottle is only partially full to provide proper drop control.
First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed.
If you think you did not get the drop of medicine into your eye properly, use another drop.
Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. Serious damage to the eye and possible loss of vision may result from using contaminated eye drops.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

For ophthalmic solution (eye drops) dosage form:
- For swelling of the cornea:
  - Adults—Use 1 drop every three or four hours.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Muro-128

Use only under the advice and supervision of a doctor.

If you experience eye pain, changes in vision, continued redness or irritation of the eye, or if your symptoms continue for more than 3 days or become worse, check with your doctor.

Importance of not contaminating the product. Do not touch the tip of the container to the eye or any surface.

Do not use if the solution changes color or becomes cloudy.

Replace cap after each use. Store container upright.

Muro-128 Side Effects

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

temporary burning sensation of the eye
temporary eye irritation

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Murocel Eye Drops

30/06/10

Generic Name: Methylcellulose (meth-il-SEL-yoo-lose)
Brand Name: Murocel

Murocel Eye Drops are used for:

Treating dry eyes. It may also be used for other conditions as determined by your doctor.

Murocel Eye Drops are an eye lubricant. It works by lubricating the eye.

Do NOT use Murocel Eye Drops if:

you are allergic to any ingredient in Murocel Eye Drops

Contact your doctor or health care provider right away if any of these apply to you.

Before using Murocel Eye Drops:

Some medical conditions may interact with Murocel Eye Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Murocel Eye Drops. However, no specific interactions with Murocel Eye Drops are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Murocel Eye Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Murocel Eye Drops:

Use Murocel Eye Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

To use Murocel Eye Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
Remove contact lenses before using Murocel Eye Drops.
Do not use Murocel Eye Drops if it becomes cloudy or changes color.
If you miss a dose of Murocel Eye Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Murocel Eye Drops.

Important safety information:

Murocel Eye Drops may cause temporary blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Murocel Eye Drops.
Different products may have different dosing instructions for CHILDREN on the package labeling. Follow the dosing instructions provided on the package labeling or by your doctor. If you are unsure of what dose to give a child, check with your doctor.
PREGNANCY and BREAST- FEEDING: If you become pregnant while taking Murocel Eye Drops, discuss with your doctor the benefits and risks of using Murocel Eye Drops during pregnancy. It is unknown if Murocel Eye Drops are excreted in breast milk. If you are or will be breast- feeding while you are using Murocel Eye Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Murocel Eye Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Temporary blurred vision.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain, redness, or irritation; severe or persistent blurred vision.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Murocel Eye Drops:

Store Murocel Eye Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Keep Murocel Eye Drops out of the reach of children and away from pets.

General information:

If you have any questions about Murocel Eye Drops, please talk with your doctor, pharmacist, or other health care provider.
Murocel Eye Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Murocel Eye Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

M,Med-facts

Comments (0)

mupirocin nasal

30/06/10

Generic Name: mupirocin nasal (mue PIR oh sin)
Brand Names: Bactroban

What is mupirocin nasal?

Mupirocin is an antibiotic that treats or prevents infection caused by bacteria.

Mupirocin nasal (for the nose) is used to prevent severe staph infections in patients and healthcare workers who may be at risk of infection during an outbreak within a hospital or other healthcare setting.

Mupirocin nasal may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about mupirocin nasal?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Mupirocin nasal is usually given for 5 days. To best protect you from infection, use this medication for the entire length of time prescribed by your doctor. Mupirocin nasal will not treat or prevent a viral infection such as the common cold or flu. Stop using mupirocin nasal and call your doctor at once if you have severe burning or stinging of your nose or eyes.

Do not use other nasal medications at the same time you apply mupirocin nasal.

What should I discuss with my health care provider before taking mupirocin nasal?

You should not use this medication if you are allergic to mupirocin. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether mupirocin nasal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Mupirocin nasal should not be used in a child younger than 12 years old.

How should I take mupirocin nasal?

Mupirocin nasal ointment is packaged in single-use tubes. Use one half of the medicine from the tube in your left nostril, and use the other half in your right nostril. After placing the ointment into your nostrils, gently press your nostrils closed and then release them, repeating for about 1 minute to help spread the ointment inside your nose.

Throw the ointment tube away after one use, even if there is still some ointment left in it.

Mupirocin nasal is usually given for 5 days. To best protect you from infection, use this medication for the entire length of time prescribed by your doctor. Mupirocin nasal will not treat or prevent a viral infection such as the common cold or flu. Store mupirocin nasal at room temperature away from moisture and heat. Do not refrigerate.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of mupirocin nasal is not expected to produce life-threatening symptoms.

What should I avoid while taking mupirocin nasal?

Avoid getting this medication in your eyes. If this does happen, rinse with water.

Do not use other nasal medications at the same time you apply mupirocin nasal.

Mupirocin nasal side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using mupirocin nasal and call your doctor at once if you have any of these serious side effects:

severe burning or stinging of your nose;
nosebleed; or
severe burning or watering of your eyes.

Less serious side effects may include:

dryness or unpleasant taste in your mouth;
headache;
ear pain;
runny or stuffy nose;
nausea, diarrhea;
itching, mild skin rash;
cough; or
sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Mupirocin nasal Dosing Information

Usual Adult Dose for Skin and Structure Infection:

Cream:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Adult Dose for Nasal Carriage of Staphylococcus aureus:

Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.

Usual Pediatric Dose for Skin and Structure Infection:

Cream:
3 months to 16 years:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
2 months to 16 years:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Pediatric Dose for Nasal Carriage of Staphylococcus aureus:

Greater than or equal to 12 years:
Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.

What other drugs will affect mupirocin nasal?

There may be other drugs that can interact with mupirocin nasal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about mupirocin nasal.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,M

Comments (0)

mupirocin topical

30/06/10

Generic Name: mupirocin topical (myoo PEER oh sin)
Brand Names: Bactroban

What is mupirocin topical?

Mupirocin is an antibiotic. Mupirocin topical prevents bacteria from growing on your skin.

Mupirocin topical is used to treat infections of the skin such as impetigo.

Mupirocin topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about mupirocin topical?

Use this medication for the full amount of time prescribed by your doctor or as recommended in the package even if you begin to feel better. Your symptoms may improve before the infection is completely healed. Avoid your eyes, nose, mouth, and lips when applying mupirocin topical. If medication gets in any of these areas, wash with water.

Watch for signs of improvement in 3 to 5 days. If your condition gets worse or does not improve, see your doctor.

Who should not use mupirocin topical?

Do not use mupirocin topical if you have ever had an allergic reaction to it.

You may not be able to use mupirocin topical if you have a very large open wound. This medication contains polyethylene glycol, which may cause damage to your kidneys if too much drug is absorbed through your skin.

Mupirocin topical is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not use mupirocin topical without first talking to your doctor if you are pregnant. Mupirocin topical passes into breast milk and may affect a nursing infant. Do not use mupirocin topical without first talking to your doctor if you are breast-feeding a baby.

How should I use mupirocin topical?

Use mupirocin topical exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands before and after using this medication.

Clean and dry the affected area. Apply a small amount of the ointment as directed.

You should notice improvement in 3 to 5 days. If the infection gets worse or does not improve, consult your doctor.

Do not use bandages that do not allow air circulation over the affected area unless otherwise directed by your doctor. A light, cotton-gauze dressing may be used to protect clothing.

Avoid getting this medication in your eyes, nose, or mouth or in large, open wounds. Store mupirocin topical at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and apply only the regular amount of mupirocin topical. Do not use a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

An overdose of mupirocin topical is rare. Consult a doctor if you suspect an overdose. No symptoms of an overdose are known.

If mupirocin topical gets in your eyes or mouth, rinse with water.

If mupirocin topical is ingested, consult a poison control center.

What should I avoid while using mupirocin topical?

Avoid using other topical preparations on the same area at the same time unless directed to do so by your doctor.

Mupirocin topical side effects

Serious side effects are not expected to occur with mupirocin topical therapy. Stop using mupirocin topical and see your doctor if you experience unusual blistering, itching, redness, peeling, dryness, or irritation of the skin.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Mupirocin topical Dosing Information

Usual Adult Dose for Skin and Structure Infection:

Cream:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Adult Dose for Nasal Carriage of Staphylococcus aureus:

Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.

Usual Pediatric Dose for Skin and Structure Infection:

Cream:
3 months to 16 years:
A small amount applied to the affected area 3 times a day for 10 days.

Ointment:
2 months to 16 years:
A small amount applied to the affected area 3 times a day for 7 to 14 days.

Usual Pediatric Dose for Nasal Carriage of Staphylococcus aureus:

Greater than or equal to 12 years:
Divide 1/2 of the ointment from the single-use tube between the nostrils and apply twice daily for 5 days.

What other drugs will affect mupirocin topical?

Other topical medications may change the way that your skin absorbs mupirocin topical. Avoid using other products on the same area at the same time unless directed to do so by your doctor.

Where can I get more information?

Your pharmacist has additional information about mupirocin topical written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,M

Comments (0)

Murine Ear Drops

30/06/10

Generic Name: carbamide peroxide (otic) (KAR ba mide per OX ide OH tik)
Brand Names: Auraphene-B, Auro Ear Drops, Debrox, Ear Wax, Ear Wax Removal, Mollifene, Murine Ear Drops

What is carbamide peroxide?

Carbamide peroxide otic (for the ears) is used to soften and loosen ear wax, making it easier to remove.

Carbamide peroxide may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about carbamide peroxide?

You should not use this medication if you are allergic to carbamide peroxide, or if you have a ruptured ear drum. Do not use carbamide peroxide if you have any signs of ear infection or injury, such as pain or other irritation, or drainage, discharge, or bleeding from the ear. Do not use this medication in a child younger than 12 years old without the advice of a doctor.

You may hear a bubbling sound inside your ear after using carbamide peroxide ear drops. This is caused by the foaming action of carbamide peroxide, which helps break up the wax inside your ear.

Do not use carbamide peroxide for longer than 4 days in a row. Call your doctor if your ear symptoms do not improve after treatment, or if they get worse. Stop using carbamide peroxide and call your doctor at once if you have a serious side effect such as dizziness, ear pain or other irritation, decreased hearing for a prolonged period of time, or discharge or bleeding from the ear.

What should I discuss with my health care provider before using carbamide peroxide?

You should not use this medication if you are allergic to carbamide peroxide, or if you have any signs of ear infection or injury such as:

ear pain, itching, or other irritation;
drainage or discharge from the ear; or
bleeding from the ear.

FDA pregnancy category C. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Do not use this medication in a child younger than 12 years old without the advice of a doctor.

How should I use carbamide peroxide?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

The usual dose of this medication for children is 1 to 5 drops per ear twice daily. The usual dose for adults is 5 to 10 drops per ear twice daily. Follow your doctor’s instructions. Carbamide peroxide may be used for up to 4 days, unless your doctor has told you otherwise.

To use the ear drops, first remove the cap from the dropper bottle. Lie down or tilt your head with your ear facing upward. Pull back on your ear gently to open up the ear canal. Hold the dropper upside down over your ear canal and drop the correct number of ear drops into the ear.

You may hear a bubbling sound inside your ear after putting in the drops. This is caused by the foaming action of carbamide peroxide, which helps break up the wax inside your ear.

After using the ear drops, stay lying down or with your head tilted for at least 5 minutes. You may use a small piece of cotton ball to plug the ear and keep the medicine from draining out. Follow your doctor’s instructions about the use of cotton.

Do not place the dropper tip into your ear, or allow the tip to touch any surface. It may become contaminated.

Wipe the tip of the medicine bottle with a clean tissue. Do not wash the dropper tip.

Carbamide peroxide may be packaged with a bulb syringe that is used to flush out your ear with water.

When filling the bulb syringe, use only warm water that is body temperature (no warmer than 98 degrees F). Do not use hot or cold water.

Hold your head sideways with your ear over a sink or bowl.

Gently pull your ear lobe back and downward to open up the ear canal. Place the tip of the bulb syringe at the opening of your ear canal. Do not insert the tip into your ear.

Squeeze the bulb syringe gently to release the water into your ear. Do not squirt the water with any force into your ear, or you could damage your ear drum.

Remove the syringe and allow the water to drain from your ear into the sink or bowl.

Do not use carbamide peroxide for longer than 4 days in a row. Call your doctor if your ear symptoms do not improve after treatment, or if they get worse.

Clean the bulb syringe by filling it with plain water and emptying it several times. Do not use soap or other cleaning chemicals. Allow the syringe to air dry.

Store the medication and the bulb syringe at room temperature away from moisture, heat, and direct light.

What happens if I miss a dose?

Since carbamide peroxide is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of carbamide peroxide is not likely to cause life-threatening symptoms.

What should I avoid while using carbamide peroxide?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using this medication.

Carbamide peroxide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using carbamide peroxide and call your doctor at once if you have a serious side effect such as:

dizziness;
ear pain, itching, or other irritation;
discharge or bleeding from the ear; or
decreased hearing for a prolonged period of time.

Less serious side effects may include:

temporary decrease in hearing after using the ear drops;
mild feeling of fullness in the ear; or
mild itching inside the ear.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect carbamide peroxide?

It is not likely that other drugs you take orally or inject will have an effect on carbamide peroxided otic. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about carbamide peroxide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,M

Comments (0)

Murine Tears Drops

30/06/10

Generic Name: Tetrahydrozoline (te-tra-hye-DROZ-oh-leen)
Brand Name: Examples include Eye Moisturizing Relief and Murine Tears

Murine Tears Drops are used for:

Temporarily relieving redness, burning, and irritation caused by dry eyes. It may also be used for other conditions as determined by your doctor.

Murine Tears Drops are an eye decongestant and lubricant. It works by constricting the blood vessels in the eye and coating the eye, which relieves redness and dryness.

Do NOT use Murine Tears Drops if:

you are allergic to any ingredient in Murine Tears Drops
you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Murine Tears Drops:

Some medical conditions may interact with Murine Tears Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have glaucoma, high blood pressure, diabetes, heart problems, or thyroid problems, or you are taking medicine for high blood pressure

Some MEDICINES MAY INTERACT with Murine Tears Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

Tricyclic antidepressants (eg, amitriptyline) because they may decrease Murine Tears Drops’s effectiveness
Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Murine Tears Drops’s side effects, such as headache, fever, and high blood pressure
Bromocriptine or cocaine because their actions and side effects may be increased by Murine Tears Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Murine Tears Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Murine Tears Drops:

Use Murine Tears Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Murine Tears Drops are for use in the eye only. Avoid contact with the nose, mouth, or other mucous membranes.
To use Murine Tears Drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
If you miss a dose of Murine Tears Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use Murine Tears Drops.

Important safety information:

Remove contact lenses before using Murine Tears Drops.
Do not use Murine Tears Drops if it becomes cloudy or changes color.
Contact your doctor if you experience changes in your vision, eye pain, irritation, soreness, or continued redness, or if your condition does not improve after 3 days.
Use Murine Tears Drops with caution in CHILDREN because they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Murine Tears Drops, discuss with your doctor the benefits and risks of using Murine Tears Drops during pregnancy. It is unknown if Murine Tears Drops are excreted in breast milk. If you are or will be breast-feeding while you are using Murine Tears Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Murine Tears Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; minor stinging when the medicine is dropped into the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Murine Tears Drops may be harmful if swallowed, especially in children.

Proper storage of Murine Tears Drops:

Store Murine Tears Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Murine Tears Drops out of the reach of children and away from pets.

General information:

If you have any questions about Murine Tears Drops, please talk with your doctor, pharmacist, or other health care provider.
Murine Tears Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Murine Tears Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

M,Med-facts

Comments (0)

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Drugs & Medications:A-Z

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30/06/10

Uses For muromonab-cd3

Before Using muromonab-cd3

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of muromonab-cd3

Dosing

Precautions While Using muromonab-cd3

muromonab-cd3 Side Effects

30/06/10

Murine Tears Plus Drops are used for:

Do NOT use Murine Tears Plus Drops if:

Before using Murine Tears Plus Drops:

How to use Murine Tears Plus Drops:

Important safety information:

Possible side effects of Murine Tears Plus Drops:

If OVERDOSE is suspected:

General information:

30/06/10

Muro 128 Ointment is used for:

Do NOT use Muro 128 Ointment if:

Before using Muro 128 Ointment:

How to use Muro 128 Ointment:

Important safety information:

Possible side effects of Muro 128 Ointment:

If OVERDOSE is suspected:

General information:

30/06/10

Muro 128 Drops are used for:

Do NOT use Muro 128 Drops if:

Before using Muro 128 Drops:

How to use Muro 128 Drops:

Important safety information:

Possible side effects of Muro 128 Drops:

If OVERDOSE is suspected:

General information:

30/06/10

Uses For Muro-128

Before Using Muro-128

Allergies

Pediatric

Geriatric

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Proper Use of sodium chloride

Dosing

Missed Dose

Storage

Precautions While Using Muro-128

Muro-128 Side Effects

30/06/10

Murocel Eye Drops are used for:

Do NOT use Murocel Eye Drops if:

Before using Murocel Eye Drops:

How to use Murocel Eye Drops:

Important safety information:

Possible side effects of Murocel Eye Drops:

If OVERDOSE is suspected:

General information:

30/06/10

What is mupirocin nasal?

What is the most important information I should know about mupirocin nasal?

What should I discuss with my health care provider before taking mupirocin nasal?

How should I take mupirocin nasal?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking mupirocin nasal?

Mupirocin nasal side effects

Mupirocin nasal Dosing Information

What other drugs will affect mupirocin nasal?

Where can I get more information?