Generic Name: Brompheniramine (brome-fen-EER-a-meen)
Brand Name: VaZol

VaZol Liquid is used for:

Temporarily relieving runny nose, watery eyes, sneezing, and itchy nose, eyes, and throat associated with hay fever or other allergies. It may also be used for other conditions as determined by your doctor.

VaZol Liquid is an antihistamine. It works by blocking the action of histamine, a chemical released during allergic reactions.

Do NOT use VaZol Liquid if:

• you are allergic to any ingredient in VaZol Liquid
• you are breast-feeding
• you are taking sodium oxybate (GHB) or you have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using VaZol Liquid:

Some medical conditions may interact with VaZol Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have narrow-angle glaucoma, increased pressure in the eye, a stomach ulcer, constipation, an enlarged prostate, the inability to urinate, asthma, overactive thyroid, a blockage of the stomach or bowels, heart disease, or high blood pressure

Some MEDICINES MAY INTERACT with VaZol Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• MAO inhibitors (eg, phenelzine) or sodium oxybate (GHB) because the risk of side effects such as severe drowsiness may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if VaZol Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use VaZol Liquid:

Use VaZol Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• VaZol Liquid may be taken with food if it upsets your stomach.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of VaZol Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use VaZol Liquid.

Important safety information:

• VaZol Liquid may cause dizziness, drowsiness, or changes in vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to VaZol Liquid. Using VaZol Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking VaZol Liquid. VaZol Liquid will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
• VaZol Liquid may contain tartrazine dye (FD&C Yellow No. 5), which can cause allergic reactions in certain patients. If you have previously had an allergic reaction to tartrazine, contact your pharmacist to determine if the medicine you are taking contains tartrazine.
• VaZol Liquid may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to VaZol Liquid. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
• Use VaZol Liquid with caution in the ELDERLY because they may be more sensitive to its effects.
• VaZol Liquid is not recommended for use in CHILDREN younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is unknown if VaZol Liquid can cause harm to the fetus. If you become pregnant while taking VaZol Liquid, discuss with your doctor the benefits and risks of using VaZol Liquid during pregnancy. It is unknown if VaZol Liquid is excreted in breast milk. Do not breast-feed while taking VaZol Liquid.

Possible side effects of VaZol Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; dizziness or lightheadedness; drowsiness; enlarged pupils; headache; loss of appetite; restlessness; sleeplessness; tension.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred or double vision; chest pain; clumsiness or unsteadiness; convulsions; fast or irregular heartbeat; hallucinations; pounding in the chest; psychotic episodes (bizarre behavior); severe dry mouth, nose, or throat; shortness of breath; sore throat and fever; trouble urinating; unusual bleeding or bruising; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include bizarre behavior; convulsions; flushing; hallucinations; severe agitation or irritability; severe drowsiness.

Proper storage of VaZol Liquid:

Store VaZol Liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep VaZol Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about VaZol Liquid, please talk with your doctor, pharmacist, or other health care provider.
• VaZol Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about VaZol Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Brompheniramine/Hydrocodone/Phenylephrine (BROME-fen-IR-a-meen/hye-droe-KOE-done/FEN-il-EF-rin)
Brand Name: VasoTuss HC

VasoTuss HC Suspension is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.

VasoTuss HC Suspension is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms, such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use VasoTuss HC Suspension if:

• you are allergic to any ingredient in VasoTuss HC Suspension or any other codeine- or morphine-related medicine (eg, codeine)
• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
• you are unable to urinate or are having an asthma attack
• you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using VasoTuss HC Suspension:

Some medical conditions may interact with VasoTuss HC Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a fast, slow, or irregular heartbeat; heart blood vessel problems; or other heart problems
• if you have a history of adrenal gland problems (eg, adrenal gland tumor); high blood pressure; diabetes; stroke; glaucoma; a blockage of your bladder, stomach, or intestines; ulcers; trouble urinating; an enlarged prostate or other prostate problems; or an overactive thyroid
• if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
• if you have or recently have had any head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures
• if you have a history of stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), gallbladder problems (eg, gallstones), or phenylketonuria, or if you have had recent abdominal surgery
• if you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with VasoTuss HC Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of VasoTuss HC Suspension’s side effects
• Cimetidine, digoxin, droxidopa, or sodium oxybate ( GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased
• Naltrexone because it may decrease VasoTuss HC Suspension’s effectiveness
• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by VasoTuss HC Suspension
• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by VasoTuss HC Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if VasoTuss HC Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use VasoTuss HC Suspension:

Use VasoTuss HC Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take VasoTuss HC Suspension by mouth with or without food.
• Shake well before each use.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of VasoTuss HC Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use VasoTuss HC Suspension.

Important safety information:

• VasoTuss HC Suspension may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use VasoTuss HC Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using VasoTuss HC Suspension without first checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Do not take diet or appetite control medicines while you are taking VasoTuss HC Suspension without checking with your doctor.
• VasoTuss HC Suspension has brompheniramine and phenylephrine in it. Before you start any new medicine, check the label to see if it has brompheniramine and phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
• If your symptoms do not get better within 5 to 7 days or if they get worse, check with your doctor.
• VasoTuss HC Suspension may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to VasoTuss HC Suspension. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• VasoTuss HC Suspension may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking VasoTuss HC Suspension for a few days before the tests.
• Tell your doctor or dentist that you take VasoTuss HC Suspension before you receive any medical or dental care, emergency care, or surgery.
• Use VasoTuss HC Suspension with caution in the ELDERLY; they may be more sensitive to its effects.
• Caution is advised when using VasoTuss HC Suspension in CHILDREN; they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking VasoTuss HC Suspension while you are pregnant. It is not known if VasoTuss HC Suspension is found in breast milk. Do not breast-feed while taking VasoTuss HC Suspension.

When used for long periods of time or at high doses, VasoTuss HC Suspension may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if VasoTuss HC Suspension stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking VasoTuss HC Suspension. This is known as DEPENDENCE or addiction.

If you suddenly stop taking VasoTuss HC Suspension, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Possible side effects of VasoTuss HC Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; severe or persistent trouble sleeping; tremor; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of VasoTuss HC Suspension:

Store VasoTuss HC Suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep VasoTuss HC Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about VasoTuss HC Suspension, please talk with your doctor, pharmacist, or other health care provider.
• VasoTuss HC Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about VasoTuss HC Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Naphazoline (naf-AZ-oh-leen)
Brand Name: Examples include Naphcon and VasoClear

VasoClear Drops are used for:

Temporarily relief of redness due to minor eye irritation. It also protects against further irritation or dryness of the eyes due to smoke, sun glare, swimming, smog, or contact lenses.

VasoClear Drops are a decongestant eye drop. It works by increasing fluid drainage from the eye, dilating the pupil, and narrowing the blood vessels of the eye.

Do NOT use VasoClear Drops if:

• you are allergic to any ingredient in VasoClear Drops
• you have narrow-angle glaucoma
• you are taking furazolidone or have taken monoamine oxidase (MAO) inhibitors (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using VasoClear Drops:

Some medical conditions may interact with VasoClear Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart disease, diabetes, high blood pressure, or an overactive thyroid

Some MEDICINES MAY INTERACT with VasoClear Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects, such as headache, increased body temperature, and high blood pressure, may be increased
• Bromocriptine or cocaine because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if VasoClear Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use VasoClear Drops:

Use VasoClear Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• If you wear contact lenses, remove them before using VasoClear Drops.
• To use VasoClear Drops, first wash your hands. Tilt your head back and with your index finger, pull the lower eyelid away from your eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Do not blink. Keep your eyes closed for 1 or 2 minutes. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from entering your medicine, do not touch the applicator tip to any surface including your eye.
• If you miss a dose of VasoClear Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use VasoClear Drops.

Important safety information:

• VasoClear Drops are for use in the eye only. Avoid contact with the nose and mouth.
• Do not use VasoClear Drops if it changes color or becomes cloudy.
• Do not exceed the recommended dose or use VasoClear Drops for longer than 3 days without checking with your doctor.
• VasoClear Drops are not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using VasoClear Drops during pregnancy. It is unknown if VasoClear Drops are excreted in breast milk. If you are or will be breast-feeding while you are using VasoClear Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of VasoClear Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dilated pupils; worsening of irritation or redness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in vision; eye pain; headache.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. VasoClear Drops may be harmful if swallowed.

Proper storage of VasoClear Drops:

Store VasoClear Drops at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep VasoClear Drops out of the reach of children and away from pets.

General information:

• If you have any questions about VasoClear Drops, please talk with your doctor, pharmacist, or other health care provider.
• VasoClear Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about VasoClear Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Naphazoline/Zinc (na-FAZ-oh-leen)
Brand Name: VasoClear-A

VasoClear-A Drops are used for:

Temporarily relieving redness, burning, and discomfort caused by minor eye irritation. It may also be used for other conditions as determined by your doctor.

VasoClear-A Drops are an eye decongestant and astringent. It works by constricting the blood vessels in the eye and coating the eye, which relieves redness and dryness.

Do NOT use VasoClear-A Drops if:

• you are allergic to any ingredient in VasoClear-A Drops
• you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using VasoClear-A Drops:

Some medical conditions may interact with VasoClear-A Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have glaucoma, high blood pressure, diabetes, heart problems, or thyroid problems, or you are taking medicine for high blood pressure

Some MEDICINES MAY INTERACT with VasoClear-A Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Tricyclic antidepressants (eg, amitriptyline) because they may decrease VasoClear-A Drops’s effectiveness
• Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of VasoClear-A Drops’s side effects, such as headache, fever, and high blood pressure
• Bromocriptine or cocaine because the risk of their side effects may be increased by VasoClear-A Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if VasoClear-A Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use VasoClear-A Drops:

Use VasoClear-A Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• VasoClear-A Drops are for use in the eye only. Avoid contact with other mucous membranes.
• To use VasoClear-A Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
• If you miss a dose of VasoClear-A Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Ask your health care provider any questions you may have about how to use VasoClear-A Drops.

Important safety information:

• Remove contact lenses before using VasoClear-A Drops.
• Do not use VasoClear-A Drops if it becomes cloudy or changes color.
• Contact your doctor if you experience changes in your vision, eye pain, irritation, soreness, or continued redness, or if your condition does not improve after 3 days.
• Do not exceed the recommended dose or use VasoClear-A Drops for longer than prescribed without checking with your doctor. Eye redness may be increased by overuse of VasoClear-A Drops.
• Use VasoClear-A Drops with caution in CHILDREN because they may be more sensitive to its effects.
• Different brands of VasoClear-A Drops may have different dosing instructions for CHILDREN on the package labeling. Follow the dosing instructions provided on the package labeling or by your doctor. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking VasoClear-A Drops, discuss with your doctor the benefits and risks of using VasoClear-A Drops during pregnancy. It is unknown if VasoClear-A Drops are excreted in breast milk. If you are or will be breast-feeding while you are using VasoClear-A Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of VasoClear-A Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; minor stinging or tingling when the medicine is dropped into the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. VasoClear-A Drops may be harmful if swallowed, especially in children.

Proper storage of VasoClear-A Drops:

Store VasoClear-A Drops at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep VasoClear-A Drops out of the reach of children and away from pets.

General information:

• If you have any questions about VasoClear-A Drops, please talk with your doctor, pharmacist, or other health care provider.
• VasoClear-A Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about VasoClear-A Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Prednisolone/Sulfacetamide (pred-NISS-oh-lone/sul-fa-SEE-ta-mide)
Brand Name: Generic only. No brands available.

Vasocidin Drops are used for:

Treating inflammation (swelling, warmth, redness, pain) of the eyes and eyelids when infection or risk of infection is present.

Vasocidin Drops are an antibacterial and corticosteroid combination. It works by reducing the itching, redness, and swelling of the eye. It also works to stop the growth of certain bacteria that cause eye infections.

Do NOT use Vasocidin Drops if:

• you are allergic to any ingredient in Vasocidin Drops, to other corticosteroids (eg, dexamethasone), or to other sulfonamides (eg, acetazolamide, celecoxib, hydrochlorothiazide, glyburide, probenecid, sulfamethoxazole, valdecoxib, zonisamide)
• you have a viral eye infection (eg, herpes simplex, vaccinia, chickenpox), tuberculosis eye infection, or fungal infection of the eye or eye structures
• you have thinning of the cornea of the eye

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vasocidin Drops:

Some medical conditions may interact with Vasocidin Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have thinning of the eye tissues (eg, cornea, sclera), other eye problems (eg, glaucoma, cataracts, nerve damage), severe dry eyes, or diabetes
• if you have recently had cataract surgery

Some MEDICINES MAY INTERACT with Vasocidin Drops. Tell your health care provider if you are taking any other medicine, especially any of the following:

• Silver-containing medicines (eg, silver nitrate) because the risk of side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vasocidin Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vasocidin Drops:

Use Vasocidin Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use Vasocidin Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
• To clear up your infection completely, use Vasocidin Drops for the full course of treatment. Keep using it even if you feel better in a few days.
• Do not use Vasocidin Drops if it is dark brown or has darkened since you began using it. Contact your doctor or pharmacist if you have questions about whether you should use Vasocidin Drops.
• Do not wear contact lenses while you are using Vasocidin Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
• If you miss a dose of Vasocidin Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Vasocidin Drops.

Important safety information:

• Vasocidin Drops may cause blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Vasocidin Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• If your symptoms do not get better within 2 days or if they get worse, check with your doctor.
• Be sure to use Vasocidin Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• Long-term or repeated use of Vasocidin Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
• Tell your doctor or dentist that you take Vasocidin Drops before you receive any medical or dental care, emergency care, or surgery.
• Do not use Vasocidin Drops for future eye problems unless directed by your doctor.
• Lab tests, including eye pressure, may be performed while you use Vasocidin Drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Vasocidin Drops should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vasocidin Drops while you are pregnant. It is not known if Vasocidin Drops are found in breast milk. Do not breast-feed while using Vasocidin Drops.

Possible side effects of Vasocidin Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Temporary burning or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain, itching, redness, swelling, irritation, or sores not present when you began using Vasocidin Drops; fever, chills, or sore throat; red, swollen, or blistered skin; severe or persistent blurred vision; unusual tiredness or weakness; yellowing of the eyes or skin

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Vasocidin Drops:

Store Vasocidin Drops at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Store away from heat and light. Keep Vasocidin Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Vasocidin Drops, please talk with your doctor, pharmacist, or other health care provider.
• Vasocidin Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Vasocidin Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Varicella (Chickenpox) Virus Vaccine (var-ih-SELL-ah)
Brand Name: Varivax

Varicella (Chickenpox) Virus Vaccine is used for:

Preventing varicella (chickenpox) infections in patients 12 months of age and older.

Varicella (Chickenpox) Virus Vaccine is a vaccine. It works by stimulating the body to produce antibodies against the virus that causes chickenpox. This helps to provide long-term protection against chickenpox.

Do NOT use Varicella (Chickenpox) Virus Vaccine if:

• you are allergic to any ingredient in Varicella (Chickenpox) Virus Vaccine, including gelatin
• you have a history of allergic reaction to neomycin
• you have blood or bone marrow problems (eg, low white blood cell or platelet levels, leukemia, lymphoma, other cancer of the blood or bone marrow)
• you are taking medicine that weakens the immune system
• you have immune system problems (eg, HIV, AIDS, cellular immune deficiency)
• you have a family history of immune system problems, unless you are medically proven to have no immune system problems
• you have active, untreated tuberculosis (TB)
• you have a fever with a respiratory illness or an active infection
• you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Varicella (Chickenpox) Virus Vaccine:

Some medical conditions may interact with Varicella (Chickenpox) Virus Vaccine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have cancer, are very ill, or have a history of immune system problems or recent infection
• if you have had a blood or platelet transfusion or have received immune globulin or varicella zoster immune globulin (VZIG) within the past 5 months

Some MEDICINES MAY INTERACT with Varicella (Chickenpox) Virus Vaccine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Corticosteroids (eg, prednisone) because the risk of infection may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Varicella (Chickenpox) Virus Vaccine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Varicella (Chickenpox) Virus Vaccine:

Use Varicella (Chickenpox) Virus Vaccine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Varicella (Chickenpox) Virus Vaccine is administered as an injection at your doctor’s office or clinic. Ask your doctor or pharmacist any questions that you may have about Varicella (Chickenpox) Virus Vaccine.
• If you miss a dose of Varicella (Chickenpox) Virus Vaccine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Varicella (Chickenpox) Virus Vaccine.

Important safety information:

• This vaccine contains a weakened form of the varicella (chickenpox) virus. This is necessary to provide the best immunity.
• The length of time that Varicella (Chickenpox) Virus Vaccine protects you from chickenpox infection is unknown.
• Avoid close contact with newborns, pregnant women who have not had chickenpox, people taking cancer chemotherapy, people who are very ill, and other people with immune system problems for 6 weeks after you receive this vaccine.
• Do not take aspirin or products containing aspirin or other salicylates (eg, bismuth) for at least 6 weeks after receiving this vaccine.
• Do not receive this vaccine for at least 5 months after blood or plasma transfusions, or administration of immune globulin or VZIG.
• You should usually not receive any immune globulin, including VZIG, for 2 months after you receive this vaccine.
• Varicella (Chickenpox) Virus Vaccine is not recommended for use in CHILDREN younger than 12 months of age. Safety and effectiveness in this age group have not been confirmed
• PREGNANCY and BREAST-FEEDING: It is unknown if this vaccine can cause harm to the fetus. Do not use this vaccine if you are pregnant. Avoid becoming pregnant while taking Varicella (Chickenpox) Virus Vaccine and for 3 months following vaccination. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Varicella (Chickenpox) Virus Vaccine. It is unknown if Varicella (Chickenpox) Virus Vaccine is excreted in breast milk. If you are or will be breast-feeding while you are using Varicella (Chickenpox) Virus Vaccine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Varicella (Chickenpox) Virus Vaccine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Fever; pain, redness, or swelling at the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chickenpox-like rash; numbness or tingling of the skin; red, swollen, or blistered skin; seizures; severe headache; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Varicella (Chickenpox) Virus Vaccine:

Varicella (Chickenpox) Virus Vaccine is usually handled and stored by a health care provider. If you are using Varicella (Chickenpox) Virus Vaccine at home, store Varicella (Chickenpox) Virus Vaccine as directed by your pharmacist or health care provider.

General information:

• If you have any questions about Varicella (Chickenpox) Virus Vaccine, please talk with your doctor, pharmacist, or other health care provider.
• Varicella (Chickenpox) Virus Vaccine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Varicella (Chickenpox) Virus Vaccine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Cefpodoxime (SEF-poe-DOX-eem)
Brand Name: Vantin

Vantin Suspension is used for:

Treating mild to moderate infections caused by certain bacteria.

Vantin Suspension is a cephalosporin antibiotic. It works by interfering with the formation of the bacteria’s cell wall so that the wall ruptures, resulting in the death of the bacteria.

Do NOT use Vantin Suspension if:

• you are allergic to any ingredient in Vantin Suspension or to any other cephalosporin antibiotic (eg, cephalexin, cefprozil)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vantin Suspension:

Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have diarrhea, a stomach or intestinal infection, or a blood clotting problem
• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin antibiotic (eg, amoxicillin) or other beta-lactam antibiotic (eg, imipenem)

Some MEDICINES MAY INTERACT with Vantin Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aminoglycosides (eg, gentamicin), cyclosporine, or diuretics (eg, furosemide, hydrochlorothiazide) because the risk of side effects on the kidney may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vantin Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vantin Suspension:

Use Vantin Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Vantin Suspension by mouth with or without food.
• Vantin Suspension works best if it is taken at the same time each day.
• To clear up your infection completely, take Vantin Suspension for the full course of treatment. Keep taking it even if you feel better in a few days.
• Shake well before each use.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure this dose.
• Vantin Suspension should not be given within 2 hours of antacids or H₂ antagonists (eg, famotidine).
• If you miss a dose of Vantin Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose, and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Vantin Suspension.

Important safety information:

• Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
• Vantin Suspension only works against bacteria; it does not treat viral infections (eg, the common cold).
• Be sure to use Vantin Suspension for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• Long-term or repeated use of Vantin Suspension may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
• Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Vantin Suspension. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vantin Suspension while you are pregnant. The medicine is found in breast milk. Do not breast-feed while taking Vantin Suspension.

Possible side effects of Vantin Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; loose stools; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; seizures; severe diarrhea; skin rash; stomach pain/cramps; vaginal irritation or discharge.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include abdominal pain; diarrhea; headache; nausea; seizures; vomiting.

Proper storage of Vantin Suspension:

Store Vantin Suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). The mixed solution may be used for up to 14 days. Keep the container tightly closed. Throw away any unused portion after 14 days. Keep Vantin Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Vantin Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Vantin Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Vantin Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Histrelin (his-TREL-in)
Brand Name: Vantas

Vantas Implant is used for:

Relieving the symptoms of prostate cancer in men. Vantas Implant is not a cure for prostate cancer.

Vantas Implant is a synthetic analogue of gonadotropin-releasing hormone (GnRH) agonist. It works by decreasing the production of certain hormones, which reduces testosterone levels in the body.

Do NOT use Vantas Implant if:

• you are allergic to any ingredient in Vantas Implant or other medicines containing GnRH
• you are female

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vantas Implant:

Some medical conditions may interact with Vantas Implant. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have urinary tract blockage or metastatic vertebral lesions

Some MEDICINES MAY INTERACT with Vantas Implant. However, no specific interactions with Vantas Implant are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vantas Implant may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vantas Implant:

Use Vantas Implant as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Vantas Implant comes with an additional patient leaflet. Read it carefully.
• Vantas Implant is inserted in a doctor’s office, hospital, or clinic.
• This implant is a small, thin, flexible tube that is placed under the skin of the inside of your upper arm. It delivers medicine to your body continuously for 12 months.
• If you miss a dose of Vantas Implant, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Vantas Implant.

Important safety information:

• The cut where the implant is placed will be covered with stitches, surgical tape, and a bandage. Do not remove the surgical strips. Allow the strips to fall off on their own after a few days.
• After the implant is placed, keep your arm clean and dry for 24 hours. Do not bathe or swim for 24 hours. Keep the bandage in place for a few days until the cut heals. Avoid heavy lifting and exercise for 7 days. Avoid bumping the site for a few days.
• You may have pain, redness, or some bruising at the insertion site of the implant. This usually goes away without treatment within 2 weeks. Call your doctor if you have unusual or prolonged bleeding, redness, or pain.
• After 12 months, your doctor will remove the implant. Your doctor may insert a new implant to continue treatment.
• Vantas Implant may cause a loss in bone mineral density. This can lead to thin and/or weak bones.
• Your doctor will check your condition during treatment to be sure the implant is present and functioning.
• Rarely, the implant may be expelled through the insertion site. If you think this may have occurred, call your doctor at once.
• LAB TESTS, including prostate-specific antigen (PSA) or testosterone levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Vantas Implant is not recommended for use in CHILDREN younger than 18 years of age; safety and effectiveness in this age group have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Vantas Implant is not for WOMEN and may cause harm to an unborn baby in a woman who is pregnant or may become pregnant.

Possible side effects of Vantas Implant:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Breast growth; bruising; constipation; decreased sex drive; erectile dysfunction (impotence); headache; hot flashes; sleeplessness; soreness, pain, tenderness, or redness at the insertion site; testicles become smaller; tiredness; weight gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; bone pain; numbness or tingling of the skin; trouble urinating or inability to urinate; weakness or loss of feeling in the legs; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Vantas Implant:

Store Vantas Implant in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C) in the unopened glass vial in the plastic pouch and carton. Protect from light. Do not freeze. Keep Vantas Implant out of the reach of children and away from pets.

General information:

• If you have any questions about Vantas Implant, please talk with your doctor, pharmacist, or other health care provider.
• Vantas Implant is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Vantas Implant. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Benzoyl Peroxide/Hydrocortisone (BEN-zoe-il per-OX-ide/hye-droe-KOR-ti-sone)
Brand Name: Vanoxide-HC

Vanoxide-HC Lotion is used for:

Treating acne.

Vanoxide-HC Lotion is a combination keratolytic agent with antibacterial actions and corticosteroid. The effectiveness of benzoyl peroxide appears to be due to its antibacterial, peeling (keratolytic), and drying actions. The corticosteroid reduces inflammation in a way that is not fully understood.

Do NOT use Vanoxide-HC Lotion if:

• you are allergic to any ingredient in Vanoxide-HC Lotion
• you have a viral skin disease

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vanoxide-HC Lotion:

Some medical conditions may interact with Vanoxide-HC Lotion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have any kind of skin infection, cuts, scrapes, or lessened blood flow to your skin
• if you have had a recent vaccination; have measles, tuberculosis, chickenpox, or shingles; or have had a positive tuberculosis test
• if you are taking prednisone or similar medicines

Some MEDICINES MAY INTERACT with Vanoxide-HC Lotion. However, no specific interactions with Vanoxide-HC Lotion are known at this time.

Ask your health care provider if Vanoxide-HC Lotion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vanoxide-HC Lotion:

Use Vanoxide-HC Lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Shake well before each use.
• Wash and completely dry the affected area. Apply a thin film of medicine to the affected area. Gently rub the medicine in until it is evenly distributed.
• Wash your hands after using Vanoxide-HC Lotion.
• If you miss a dose of Vanoxide-HC Lotion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Vanoxide-HC Lotion.

Important safety information:

• Use on the skin only. Avoid getting Vanoxide-HC Lotion in your eyes, on the inside of your nose or mouth, on highly inflamed or damaged skin, or on your lips. If you get Vanoxide-HC Lotion in your eyes, immediately wash them out with cool tap water.
• Avoid applying Vanoxide-HC Lotion to raw or irritated skin, including sunburns, or to open wounds.
• Several weeks may pass before you see improvement in your acne. Continue to use Vanoxide-HC Lotion for the full time recommended by your doctor. If your acne does not improve or if it gets worse, check with your doctor.
• Talk with your doctor before you use any other medicines, special cleansers, aftershave, or cosmetics on your skin.
• Vanoxide-HC Lotion may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Vanoxide-HC Lotion. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Vanoxide-HC Lotion may cause bleaching. Avoid contact with hair, fabrics, or carpeting.
• Vanoxide-HC Lotion should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vanoxide-HC Lotion while you are pregnant. It is not known if Vanoxide-HC Lotion is found in breast milk. If you are or will be breast-feeding while you use Vanoxide-HC Lotion, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Vanoxide-HC Lotion:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; mild irritation or stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; dizziness; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning, cracking, itching; excessive hair growth; extreme dryness; inflamed hair follicles; inflammation around the mouth; irritation, redness, peeling, or tenderness not present before you began using Vanoxide-HC Lotion; swelling; thinning, softening, or discoloration of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include excessive scaling; flushing; redness; swelling.

Proper storage of Vanoxide-HC Lotion:

Store Vanoxide-HC Lotion at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Throw away any unused medicine after 3 months. Keep Vanoxide-HC Lotion out of the reach of children and away from pets.

General information:

• If you have any questions about Vanoxide-HC Lotion, please talk with your doctor, pharmacist, or other health care provider.
• Vanoxide-HC Lotion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Vanoxide-HC Lotion. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Acetaminophen/Aspirin/Caffeine (a-SEET-a-MIN-oh-fen/AS-pir-in/KAF-een)
Brand Name: Examples include Excedrin and Vanquish

Vanquish is used for:

Relieving headaches, migraine headaches, toothaches, muscle aches, premenstrual or menstrual aches, or other minor aches and pains (eg, due to sinusitis or colds). It may also be used for other conditions as determined by your doctor.

Vanquish is an analgesic and antipyretic combination. It works by blocking substances in the body that cause pain and inflammation.

Do NOT use Vanquish if:

• you are allergic to any ingredient in Vanquish
• you are a child or teenager with influenza (flu) or chickenpox
• you have bleeding problems, such as hemophilia, von Willebrand disease, or low blood platelets
• you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin, tartrazine, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, celecoxib, ibuprofen, naproxen)
• you are taking another medicine that contains acetaminophen

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vanquish:

Some medical conditions may interact with Vanquish. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol abuse or if you consume 3 or more alcohol-containing drinks every day
• if you are 60 years of age or older
• if you are taking a diuretic, a corticosteroid (eg, prednisone), an anticoagulant (eg, warfarin), or ketorolac
• if you have asthma, bleeding or clotting problems, growths in the nose (nasal polyps), kidney or liver problems, hepatitis, severe heart problems, stomach or peptic ulcers (bleeding ulcers), heartburn, upset stomach, stomach pain, influenza (flu) or chickenpox, vitamin K deficiency, anxiety, or trouble sleeping
• if the patient is a child with a stroke, a weakened blood vessel (cerebral aneurysm) or bleeding in the brain, or Kawasaki syndrome (a rare inflammation causing heart problems in children)

Some MEDICINES MAY INTERACT with Vanquish. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Carbonic anhydrase inhibitors (eg, acetazolamide) because they may decrease Vanquish’s effectiveness
• Anticoagulants (eg, warfarin), clopidogrel, heparin, ketorolac, NSAIDs (eg, celecoxib, ibuprofen, naproxen), or serotonin reuptake inhibitors (eg, fluoxetine) because the risk of bleeding may be increased
• Insulin, isoniazid, oral hypoglycemics (eg, glyburide, repaglinide), or quinolone antibiotics (eg, ciprofloxacin) because the risk of their side effects may be increased by Vanquish
• Methotrexate, theophylline, or valproic acid because their actions and the risk of their side effects may be increased by Vanquish
• Probenecid or sulfinpyrazone because their effectiveness may be decreased by Vanquish

This may not be a complete list of all interactions that may occur. Ask your health care provider if Vanquish may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Vanquish:

Use Vanquish as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Vanquish by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Take Vanquish with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Vanquish.
• Use Vanquish exactly as directed on the package, unless instructed differently by your doctor. If you are taking Vanquish without a prescription, follow any warnings and precautions on the label.
• If you miss a dose of Vanquish and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Vanquish.

Important safety information:

• Vanquish has acetaminophen, aspirin, and caffeine in it. Before you start any new medicine, check the label to see if it has acetaminophen, aspirin, or caffeine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Vanquish may harm your liver. Your risk may be greater if you drink alcohol while you are using Vanquish. Talk to your doctor before you take Vanquish or other fever reducers if you drink more than 3 drinks with alcohol per day.
• Aspirin has been linked to a serious illness called Reye syndrome. Do not give Vanquish to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
• Avoid large amounts of food or drink that have caffeine (eg, coffee, tea, cocoa, cola, chocolate). This includes any medicines that contain caffeine.
• Serious stomach ulcers or bleeding can occur with the use of Vanquish. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Vanquish with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
• Vanquish may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
• Tell your doctor or dentist that you take Vanquish before you receive any medical or dental care, emergency care, or surgery.
• Do not take Vanquish for at least 7 days after any surgery unless directed by your health care provider.
• If your pain does not get better or becomes worse, or if you have a fever that becomes worse or lasts for more than 3 days, contact your doctor.
• Vanquish may cause false results with some in-home test kits for blood cholesterol. Check with your doctor or pharmacist if you are taking Vanquish and need to check your blood cholesterol at home.
• Different brands of Vanquish may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Vanquish while you are pregnant. Vanquish is not recommended during the last 3 months (third trimester) of pregnancy because it may cause harm to the fetus. Vanquish is found in breast milk. If you are or will be breast-feeding while you use Vanquish, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Vanquish:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Heartburn; nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; confusion; dark urine or pale stools; fainting; hearing loss; ringing in the ears; severe stomach pain; unusual tiredness; vomiting blood; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating; extreme fatigue; irregular heartbeat; low blood pressure; stomach pain; vomiting; yellowing of the skin or eyes.

Proper storage of Vanquish:

Store Vanquish at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Vanquish out of the reach of children and away from pets.

General information:

• If you have any questions about Vanquish, please talk with your doctor, pharmacist, or other health care provider.
• Vanquish is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Vanquish. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.