Generic Name: Acetaminophen (a-seet-a-MIN-oh-fen)
Brand Name: Examples include Mapap Children’s and Tylenol Children’s

Tylenol Children’s Suspension is used for:

Treating minor aches and pains due to the common cold, flu, headaches, sore throat, immunizations and toothaches, and for temporarily reducing fever.

Tylenol Children’s Suspension is an analgesic and antipyretic (lowers fever). It works by lowering a chemical in the brain that stimulates pain nerves and the heat-regulating center in the brain.

Do NOT use Tylenol Children’s Suspension if:

• you are allergic to any ingredient in Tylenol Children’s Suspension

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tylenol Children’s Suspension:

Some medical conditions may interact with Tylenol Children’s Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol abuse or you drink more than 3 alcohol-containing drinks every day
• if you have liver or kidney problems or hepatitis

Some MEDICINES MAY INTERACT with Tylenol Children’s Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Isoniazid because the risk of liver problems may be increased
• Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Tylenol Children’s Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tylenol Children’s Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tylenol Children’s Suspension:

Use Tylenol Children’s Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tylenol Children’s Suspension by mouth with or without food.
• Shake well before each use.
• Find the right dose on chart that comes with Tylenol Children’s Suspension. If possible, use weight to dose; otherwise use age.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Replace original bottle cap to maintain child resistance.
• If you miss a dose of Tylenol Children’s Suspension and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tylenol Children’s Suspension.

Important safety information:

• Tylenol Children’s Suspension has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Tylenol Children’s Suspension may harm your liver. Your risk may be greater if you drink alcohol while you are using Tylenol Children’s Suspension. Talk to your doctor before you take Tylenol Children’s Suspension or other fever reducers if you drink more than 3 drinks with alcohol per day.
• Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use for more than 2 days or give to children younger than 3 years old unless directed by a doctor.
• Tylenol Children’s Suspension may cause the results of some in-home test kits for blood cholesterol to be wrong. Check with your doctor or pharmacist if you are taking Tylenol Children’s Suspension and need to check your blood cholesterol at home.
• For pain and fever in ADULTS: Stop use of Tylenol Children’s Suspension and ask your doctor if pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, or new symptoms occur or redness or swelling is present.
• For pain and fever in CHILDREN: Stop use and ask a doctor if fever gets worse or lasts more than 3 days, pain gets worse or lasts more than 5 days, or redness or swelling is present or any new symptoms appear.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tylenol Children’s Suspension while you are pregnant. Tylenol Children’s Suspension is found in breast milk. If you are or will be breast-feeding while you use Tylenol Children’s Suspension, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tylenol Children’s Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine or pale stools; unusual fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating; extreme fatigue; nausea and vomiting; stomach pain.

Proper storage of Tylenol Children’s Suspension:

Store Tylenol Children’s Suspension at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tylenol Children’s Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Tylenol Children’s Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Tylenol Children’s Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tylenol Children’s Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Acetaminophen (a-seet-a-MIN-oh-fen)
Brand Name: Examples include Tylenol 8 Hour and Tylenol Arthritis Pain

Tylenol Arthritis Pain Controlled-Release Tablets are used for:

Treating minor aches and pains due to headache, muscle aches, backache, arthritis, the common cold, menstrual cramps, and toothache.

Tylenol Arthritis Pain Controlled-Release Tablets are an analgesic and antipyretic (lowers fever). It works by lowering a chemical in the brain that stimulates pain nerves and the heat-regulating center in the brain.

Do NOT use Tylenol Arthritis Pain Controlled-Release Tablets if:

• you are allergic to any ingredient in Tylenol Arthritis Pain Controlled-Release Tablets

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tylenol Arthritis Pain Controlled-Release Tablets:

Some medical conditions may interact with Tylenol Arthritis Pain Controlled-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol abuse or you drink more than 3 alcohol-containing drinks every day
• if you have liver or kidney problems or hepatitis

Some MEDICINES MAY INTERACT with Tylenol Arthritis Pain Controlled-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Isoniazid because the risk of liver problems may be increased
• Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Tylenol Arthritis Pain Controlled-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tylenol Arthritis Pain Controlled-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tylenol Arthritis Pain Controlled-Release Tablets:

Use Tylenol Arthritis Pain Controlled-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tylenol Arthritis Pain Controlled-Release Tablets by mouth with or without food.
• Swallow Tylenol Arthritis Pain Controlled-Release Tablets whole. Do not break, crush, or chew before swallowing.
• Replace original bottle cap to maintain child resistance.
• If you miss a dose of Tylenol Arthritis Pain Controlled-Release Tablets and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tylenol Arthritis Pain Controlled-Release Tablets.

Important safety information:

• Tylenol Arthritis Pain Controlled-Release Tablets has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Tylenol Arthritis Pain Controlled-Release Tablets may harm your liver. Your risk may be greater if you drink alcohol while you are using Tylenol Arthritis Pain Controlled-Release Tablets. Talk to your doctor before you take Tylenol Arthritis Pain Controlled-Release Tablets or other fever reducers if you drink more than 3 drinks with alcohol per day.
• Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use for more than 2 days or give to children younger than 3 years old unless directed by a doctor.
• Tylenol Arthritis Pain Controlled-Release Tablets may cause the results of some in-home test kits for blood cholesterol to be wrong. Check with your doctor or pharmacist if you are taking Tylenol Arthritis Pain Controlled-Release Tablets and need to check your blood cholesterol at home.
• For pain and fever in ADULTS: Stop use of Tylenol Arthritis Pain Controlled-Release Tablets and ask your doctor if pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, or new symptoms occur or redness or swelling is present.
• For pain and fever in CHILDREN: Stop use and ask a doctor if fever gets worse or lasts more than 3 days, pain gets worse or lasts more than 5 days, or redness or swelling is present or any new symptoms appear.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tylenol Arthritis Pain Controlled-Release Tablets while you are pregnant. Tylenol Arthritis Pain Controlled-Release Tablets are found in breast milk. If you are or will be breast-feeding while you use Tylenol Arthritis Pain Controlled-Release Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tylenol Arthritis Pain Controlled-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine or pale stools; unusual fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating; extreme fatigue; nausea and vomiting; stomach pain.

Proper storage of Tylenol Arthritis Pain Controlled-Release Tablets:

Store Tylenol Arthritis Pain Controlled-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tylenol Arthritis Pain Controlled-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Tylenol Arthritis Pain Controlled-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
• Tylenol Arthritis Pain Controlled-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tylenol Arthritis Pain Controlled-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Acetaminophen (a-seet-a-MIN-oh-fen)
Brand Name: Examples include Mapap and Tylenol

Tylenol Suppositories are used for:

Treating minor aches and pains due to headache, muscle aches, backache, arthritis, the common cold, flu, toothache, menstrual cramps, and immunizations, and for temporarily reducing fever.

Tylenol Suppositories are an analgesic and antipyretic (lowers fever). It works by lowering a chemical in the brain that stimulates pain nerves and the heat-regulating center in the brain.

Do NOT use Tylenol Suppositories if:

• you are allergic to any ingredient in Tylenol Suppositories

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tylenol Suppositories:

Some medical conditions may interact with Tylenol Suppositories. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol abuse or you drink more than 3 alcohol-containing drinks every day
• if you have liver or kidney problems

Some MEDICINES MAY INTERACT with Tylenol Suppositories. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Isoniazid because the risk of liver problems may be increased
• Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Tylenol Suppositories

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tylenol Suppositories may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tylenol Suppositories:

Use Tylenol Suppositories as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Wash your hands before and after using Tylenol Suppositories. If the suppository is too soft to use, put it in the refrigerator for about 15 minutes. You may also run cold water over it. Remove the wrapper. Moisten the suppository with cool water. Lie down on your side. Insert the pointed end of the suppository into the rectum. Use your finger to push it in completely.
• If you miss a dose of Tylenol Suppositories and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tylenol Suppositories.

Important safety information:

• Tylenol Suppositories has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Tylenol Suppositories may harm your liver. Your risk may be greater if you drink alcohol while you are using Tylenol Suppositories. Talk to your doctor before you take Tylenol Suppositories or other fever reducers if you drink more than 3 drinks with alcohol per day.
• Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use for more than 2 days or give to children younger than 3 years old unless directed by a doctor.
• Tylenol Suppositories may cause the results of some in-home test kits for blood cholesterol to be wrong. Check with your doctor or pharmacist if you are taking Tylenol Suppositories and need to check your blood cholesterol at home.
• For pain and fever in CHILDREN: Stop use and ask a doctor if fever gets worse or lasts more than 3 days, pain gets worse or lasts more than 5 days, or redness or swelling is present or any new symptoms appear.
• For pain and fever in ADULTS: Stop use of Tylenol Suppositories and ask your doctor if pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, or new symptoms occur or redness or swelling is present.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tylenol Suppositories while you are pregnant. Acetaminophen is found in breast milk. If you are or will be breast-feeding while you use Tylenol Suppositories, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tylenol Suppositories:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine or pale stools; stomach pain; unusual fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating, extreme fatigue; nausea and vomiting; stomach pain.

Proper storage of Tylenol Suppositories:

Store Tylenol Suppositories at room temperature, between 35 and 80 degrees F (2 and 27 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tylenol Suppositories out of the reach of children and away from pets.

General information:

• If you have any questions about Tylenol Suppositories, please talk with your doctor, pharmacist, or other health care provider.
• Tylenol Suppositories are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tylenol Suppositories. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Acetaminophen (a-seet-a-MIN-oh-fen)
Brand Name: Examples include Tylenol 8 Hour and Tylenol Arthritis Pain

Tylenol 8 Hour Controlled-Release Tablets are used for:

Treating minor aches and pains due to headache, muscle aches, backache, arthritis, the common cold, menstrual cramps, and toothache.

Tylenol 8 Hour Controlled-Release Tablets are an analgesic and antipyretic (lowers fever). It works by lowering a chemical in the brain that stimulates pain nerves and the heat-regulating center in the brain.

Do NOT use Tylenol 8 Hour Controlled-Release Tablets if:

• you are allergic to any ingredient in Tylenol 8 Hour Controlled-Release Tablets

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tylenol 8 Hour Controlled-Release Tablets:

Some medical conditions may interact with Tylenol 8 Hour Controlled-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of alcohol abuse or you drink more than 3 alcohol-containing drinks every day
• if you have liver or kidney problems or hepatitis

Some MEDICINES MAY INTERACT with Tylenol 8 Hour Controlled-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Isoniazid because the risk of liver problems may be increased
• Anticoagulants (eg, warfarin) because the risk of their side effects, including bleeding, may be increased by Tylenol 8 Hour Controlled-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tylenol 8 Hour Controlled-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tylenol 8 Hour Controlled-Release Tablets:

Use Tylenol 8 Hour Controlled-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tylenol 8 Hour Controlled-Release Tablets by mouth with or without food.
• Swallow Tylenol 8 Hour Controlled-Release Tablets whole. Do not break, crush, or chew before swallowing.
• Replace original bottle cap to maintain child resistance.
• If you miss a dose of Tylenol 8 Hour Controlled-Release Tablets and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tylenol 8 Hour Controlled-Release Tablets.

Important safety information:

• Tylenol 8 Hour Controlled-Release Tablets has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Tylenol 8 Hour Controlled-Release Tablets may harm your liver. Your risk may be greater if you drink alcohol while you are using Tylenol 8 Hour Controlled-Release Tablets. Talk to your doctor before you take Tylenol 8 Hour Controlled-Release Tablets or other fever reducers if you drink more than 3 drinks with alcohol per day.
• Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use for more than 2 days or give to children younger than 3 years old unless directed by a doctor.
• Tylenol 8 Hour Controlled-Release Tablets may cause the results of some in-home test kits for blood cholesterol to be wrong. Check with your doctor or pharmacist if you are taking Tylenol 8 Hour Controlled-Release Tablets and need to check your blood cholesterol at home.
• For pain and fever in ADULTS: Stop use of Tylenol 8 Hour Controlled-Release Tablets and ask your doctor if pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days, or new symptoms occur or redness or swelling is present.
• For pain and fever in CHILDREN: Stop use and ask a doctor if fever gets worse or lasts more than 3 days, pain gets worse or lasts more than 5 days, or redness or swelling is present or any new symptoms appear.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tylenol 8 Hour Controlled-Release Tablets while you are pregnant. Tylenol 8 Hour Controlled-Release Tablets are found in breast milk. If you are or will be breast-feeding while you use Tylenol 8 Hour Controlled-Release Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tylenol 8 Hour Controlled-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine or pale stools; unusual fatigue; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dark urine; excessive sweating; extreme fatigue; nausea and vomiting; stomach pain.

Proper storage of Tylenol 8 Hour Controlled-Release Tablets:

Store Tylenol 8 Hour Controlled-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tylenol 8 Hour Controlled-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Tylenol 8 Hour Controlled-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
• Tylenol 8 Hour Controlled-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tylenol 8 Hour Controlled-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Epinephrine (EP-i-NEF-rin)
Brand Name: Adrenaclick or Twinject

Twinject Auto-Injector is used for:

Treating severe allergic reactions (eg, difficulty breathing; rash; hives; itching; tightness in the chest; swelling of the mouth, lips, or tongue) caused by insect stings or bites, foods, drugs, or other causes. It may also be used for other conditions as determined by your doctor.

Twinject Auto-Injector is a sympathomimetic. It works on different receptors in the body to relax the smooth muscle of the lungs, which improves breathing. It also blocks histamine, which decreases rash, hives, and swelling.

Do NOT use Twinject Auto-Injector if:

• you are allergic to any ingredient in Twinject Auto-Injector, unless your doctor tells you otherwise

Contact your doctor or health care provider right away if any of these apply to you.

Before using Twinject Auto-Injector:

Some medical conditions may interact with Twinject Auto-Injector. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances (eg, sulfites)
• if you have glaucoma, heart disease, chest pain, high blood pressure, blood vessel problems, diabetes, Parkinson disease, thyroid problems, mood or mental disorders, depression, asthma, or an irregular heartbeat

Some MEDICINES MAY INTERACT with Twinject Auto-Injector. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Alpha-blockers (eg, prazosin), beta-blockers (eg, propanolol), droxidopa, ergot alkaloids (eg, ergotamine), or phenothiazines (eg, chlorpromazine) because the risk of high or low blood pressure and fast or slow heartbeat may be increased
• Bromocriptine, furazolidone, linezolid, or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects, such as headache, high temperature, and high blood pressure, may be increased
• Antihistamines (eg, diphenhydramine), catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), digoxin, diuretics (eg, furosemide, hydrochlorothiazide), levothyroxine, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), or medicines for irregular heartbeat (eg, quinidine) because they may increase the risk of Twinject Auto-Injector’s side effects
• Guanethidine because its effectiveness may be decreased by Twinject Auto-Injector

This may not be a complete list of all interactions that may occur. Ask your health care provider if Twinject Auto-Injector may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Twinject Auto-Injector:

Use Twinject Auto-Injector as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Twinject Auto-Injector. Talk to your pharmacist if you have questions about this information.
• Twinject Auto-Injector may be given as an injection at your doctor’s office, hospital, or clinic. If you will be using Twinject Auto-Injector at home, a health care provider will teach you how to use it. Be sure you understand how to use Twinject Auto-Injector. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Check Twinject Auto-Injector regularly. Replace the injector unit if it contains particles, is discolored (pink or brown), or is cracked or damaged in any way.
• Inject Twinject Auto-Injector only into the outer thigh. Do not inject into the buttocks or into a vein.
• Immediately after use, go to the nearest hospital emergency room. You may need further medical attention. Tell the doctor or health care provider that you have received an injection of epinephrine. Show the thigh where the injection was given to the doctor. Give your used auto-injector to the doctor for inspection and proper disposal.
• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
• Twinject Auto-Injector is usually given as a one-time dose in an emergency situation. If you are unable to use Twinject Auto-Injector, seek medical attention immediately.
• If you miss a dose of Twinject Auto-Injector, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Twinject Auto-Injector.

Important safety information:

• Never put your thumb, fingers, or hand over the red tip of the auto-injector. Do NOT remove the green or red cap until ready to use.
• Only inject Twinject Auto-Injector into the outer thigh. Never inject Twinject Auto-Injector into hands, fingers, feet, or toes. Doing so may cause a loss of blood flow and result in tissue damage to these areas. If you accidentally inject Twinject Auto-Injector into any of these areas, seek immediate emergency medical attention.
• It may be helpful to train others how to give Twinject Auto-Injector in case you are unable to give it to yourself during a reaction.
• Diabetes patients – Twinject Auto-Injector may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
• Patients with Parkinson disease may notice a temporary worsening of symptoms (eg, uncontrolled muscle movements). If these symptoms persist, contact your doctor.
• Use Twinject Auto-Injector with caution in the ELDERLY; they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Twinject Auto-Injector while you are pregnant. It is not known if Twinject Auto-Injector is found in breast milk. If you are or will be breast-feeding while you use Twinject Auto-Injector, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Twinject Auto-Injector:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; difficulty sleeping; dizziness; fearfulness; headache; nausea; nervousness; paleness; sweating; tremors; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest pain; extreme paleness or coldness of the skin; fast or irregular heartbeat; one-sided weakness; severe headache or dizziness; trouble breathing.

Proper storage of Twinject Auto-Injector:

Store Twinject Auto-Injector at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in the carrying case provided. Do not refrigerate or freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Twinject Auto-Injector out of the reach of children and away from pets.

General information:

• If you have any questions about Twinject Auto-Injector, please talk with your doctor, pharmacist, or other health care provider.
• Twinject Auto-Injector is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Twinject Auto-Injector. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Carbetapentane/Guaifenesin (kar-bay-ta-PEN-tane/gwye-FEN-e-sin)
Brand Name: Examples include Oratuss and Tusso-ZR

Tusso-ZR Liquid is used for:

Relieving unproductive cough and reducing mucus in the chest due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Tusso-ZR Liquid is a cough suppressant and expectorant combination. The cough suppressant works in the brain to help decrease the cough reflex. The expectorant works by thinning mucus (phlegm) in the lungs, making it less sticky and easier to cough up. This makes coughs more productive.

Do NOT use Tusso-ZR Liquid if:

• you are allergic to any ingredient in Tusso-ZR Liquid
• you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) with the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tusso-ZR Liquid:

Some medical conditions may interact with Tusso-ZR Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have chronic cough due to smoking, asthma, chronic bronchitis, or emphysema, or if your cough produces large amounts of mucus
• if you have a history of heart problems, high blood pressure, prostate problems, an overactive thyroid, diabetes, or glaucoma

Some MEDICINES MAY INTERACT with Tusso-ZR Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• MAOIs (eg, phenelzine) because they may increase the risk of Tusso-ZR Liquid’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tusso-ZR Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tusso-ZR Liquid:

Use Tusso-ZR Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tusso-ZR Liquid by mouth with or without food.
• Drinking extra fluids while you are taking Tusso-ZR Liquid is recommended. Check with your doctor for instructions.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Tusso-ZR Liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tusso-ZR Liquid.

Important safety information:

• Tusso-ZR Liquid may cause drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Tusso-ZR Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tusso-ZR Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Do not use Tusso-ZR Liquid for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
• If cough persists for more than 1 week or is accompanied by a fever, contact your health care provider. A persistent cough could be a sign of a serious condition.
• Tusso-ZR Liquid may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Tusso-ZR Liquid.
• Caution is advised when using Tusso-ZR Liquid in CHILDREN; they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tusso-ZR Liquid while you are pregnant. It is not known if Tusso-ZR Liquid is found in breast milk. If you are or will be breast-feeding while you use Tusso-ZR Liquid, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tusso-ZR Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Drowsiness; dry mouth, nose, or throat; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include restlessness; seizures; severe agitation.

Proper storage of Tusso-ZR Liquid:

Store Tusso-ZR Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tusso-ZR Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Tusso-ZR Liquid, please talk with your doctor, pharmacist, or other health care provider.
• Tusso-ZR Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tusso-ZR Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Guaifenesin/Hydrocodone (gwye-FEN-e-sin/hye-droe-KOE-done)
Brand Name: Tusso-HC

Tusso-HC Sustained-Release Tablets are used for:

Relieving cough and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Tusso-HC Sustained-Release Tablets are a cough suppressant and expectorant combination. It works by loosening mucus and lung secretions in the chest, and making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Tusso-HC Sustained-Release Tablets if:

• you are allergic to any ingredient in Tusso-HC Sustained-Release Tablets or any other codeine or morphine-related medicine (eg, oxycodone)
• you are taking sodium oxybate (GHB)
• you have increased pressure in the brain, trouble breathing, or diarrhea due to antibiotic use

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tusso-HC Sustained-Release Tablets:

Some medical conditions may interact with Tusso-HC Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, stroke, adrenal gland problems, or an underactive thyroid
• if you have a history of stomach problems, bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery
• if you have breathing or lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus
• if you have recently had any head injury, brain injury or tumor, infection of the brain or nervous system, epilepsy, or seizures
• if you have a history of alcohol abuse, drug abuse, or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Tusso-HC Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cimetidine because it may increase the risk of Tusso-HC Sustained-Release Tablets’s side effects
• Barbiturates (eg, phenobarbital) or sodium oxybate (GHB) because the risk of severe drowsiness or breathing problems may be increased
• Naltrexone because it may decrease Tusso-HC Sustained-Release Tablets’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tusso-HC Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tusso-HC Sustained-Release Tablets:

Use Tusso-HC Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tusso-HC Sustained-Release Tablets by mouth with or without food.
• Swallow Tusso-HC Sustained-Release Tablets whole. Do not break, crush, or chew before swallowing.
• Drink plenty of water while taking Tusso-HC Sustained-Release Tablets.
• If you miss a dose of Tusso-HC Sustained-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tusso-HC Sustained-Release Tablets.

Important safety information:

• Tusso-HC Sustained-Release Tablets may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Tusso-HC Sustained-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
• If your symptoms do not bet better within 5 to 7 days or if they get worse, check with your doctor.
• Tusso-HC Sustained-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Tusso-HC Sustained-Release Tablets.
• Tell your doctor or dentist that you take Tusso-HC Sustained-Release Tablets before you receive any medical or dental care, emergency care, or surgery.
• Use Tusso-HC Sustained-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.
• Tusso-HC Sustained-Release Tablets should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tusso-HC Sustained-Release Tablets while you are pregnant. It is not known if Tusso-HC Sustained-Release Tablets are found in breast milk. Do not breast-feed while taking Tusso-HC Sustained-Release Tablets.

Possible side effects of Tusso-HC Sustained-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; change in amount of urine; difficulty urinating; hearing change or loss; mental or mood changes; severe drowsiness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Tusso-HC Sustained-Release Tablets:

Store Tusso-HC Sustained-Release Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tusso-HC Sustained-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Tusso-HC Sustained-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
• Tusso-HC Sustained-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tusso-HC Sustained-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Chlorpheniramine/Hydrocodone (KLOR-fen-IR-a-meen/hye-droe-KOE-done)
Brand Name: Tussionex Pennkinetic

Tussionex Pennkinetic Extended-Release Suspension is used for:

Treating symptoms of the common cold, flu, or hayfever and other upper respiratory allergies such as cough, runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes. It may also be used for other conditions as determined by your doctor.

Tussionex Pennkinetic Extended-Release Suspension is a narcotic antitussive (cough suppressant) and antihistamine combination. The antitussive works by suppressing the cough center in the brain. The antihistamine works by blocking the action of histamine, which reduces the symptoms of an allergic reaction such as itch, watery eyes and runny nose.

Do NOT use Tussionex Pennkinetic Extended-Release Suspension if:

• you are allergic to any ingredient in Tussionex Pennkinetic Extended-Release Suspension or any other codeine or morphine related medicine (eg, codeine, oxycodone)
• you have diarrhea associated with poisoning, antibiotic use, or a bacterial infection (from eating or drinking contaminated food or water)
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tussionex Pennkinetic Extended-Release Suspension:

Some medical conditions may interact with Tussionex Pennkinetic Extended-Release Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have or have ever had a history of alcohol or substance abuse or narcotic dependence, or if you consume more than 3 alcohol-containing drinks per day
• if you have had suicidal thoughts or behaviors
• if you have increased pressure in the eyes or glaucoma, or you are at risk for glaucoma
• if you have acute head injury, increased pressure in the head, brain injury or tumor, epilepsy or seizures, or Reye syndrome
• if you are having an asthma attack or have lung or breathing problems, including shortness of breath or sleep apnea
• if you have a stomach or intestinal problem; chronic inflammation and ulceration of the bowel; chronic constipation; difficulty urinating; an enlarged prostate gland; heart problems, including heart failure; kidney or liver problems; low blood pressure; Parkinson disease; the blood disorder porphyria; stomach, intestinal, or urinary blockage; or thyroid problems
• if you have had recent surgery

Some MEDICINES MAY INTERACT with Tussionex Pennkinetic Extended-Release Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturate anesthetics (eg, thiopental), cimetidine, or sodium oxybate (GHB) because the risk of severe drowsiness and breathing problems may be increased
• Anticholinergics (eg, hyoscyamine) because the risk of severe bowel problems (eg, paralytic ileus) may be increased
• Rifampin because it may decrease Tussionex Pennkinetic Extended-Release Suspension’s effectiveness
• Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) or tricyclic antidepressants (eg, imipramine) because the risk of their side effects or Tussionex Pennkinetic Extended-Release Suspension’s side effects may be increased
• Naltrexone because the effectiveness of Tussionex Pennkinetic Extended-Release Suspension will be decreased and withdrawal symptoms may occur in patients who have become physically dependent on opioids. You must not take naltrexone until you have stopped taking Tussionex Pennkinetic Extended-Release Suspension for 7 to 10 days and after a naloxone challenge test is negative

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussionex Pennkinetic Extended-Release Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tussionex Pennkinetic Extended-Release Suspension:

Use Tussionex Pennkinetic Extended-Release Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tussionex Pennkinetic Extended-Release Suspension by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Shake well before each use.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Tussionex Pennkinetic Extended-Release Suspension and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussionex Pennkinetic Extended-Release Suspension.

Important safety information:

• Tussionex Pennkinetic Extended-Release Suspension may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Tussionex Pennkinetic Extended-Release Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tussionex Pennkinetic Extended-Release Suspension; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• If your symptoms do not get better within 7 days or if you develop a high fever or persistent headache, check with your doctor.
• Tell your doctor or dentist that you take Tussionex Pennkinetic Extended-Release Suspension before you receive any medical or dental care, emergency care, or surgery.
• The risk of severe breathing problems may be greater if you take Tussionex Pennkinetic Extended-Release Suspension in high doses. Do NOT take more than the recommended dose without checking with your doctor.
• Use Tussionex Pennkinetic Extended-Release Suspension with caution in the ELDERLY; they may be more sensitive to its effects, especially possible breathing problems and drowsiness.
• Caution is advised when using Tussionex Pennkinetic Extended-Release Suspension in CHILDREN with lung or breathing problems (eg, croup); they may be more sensitive to its effects.
• Tussionex Pennkinetic Extended-Release Suspension should not be used in CHILDREN younger than 6 years old; they may be more sensitive to serious and even life-threatening breathing problems from Tussionex Pennkinetic Extended-Release Suspension.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tussionex Pennkinetic Extended-Release Suspension while you are pregnant. It is not known if Tussionex Pennkinetic Extended-Release Suspension is found in breast milk. Do not breast-feed while taking Tussionex Pennkinetic Extended-Release Suspension.

When used for long periods of time or at high doses, Tussionex Pennkinetic Extended-Release Suspension may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Tussionex Pennkinetic Extended-Release Suspension stops working well. Do not take more than prescribed.

Some people who use Tussionex Pennkinetic Extended-Release Suspension for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. The early sign of addiction is medicine ineffectiveness. Dependence is not an issue in terminal illness where pain relief is more important. If using Tussionex Pennkinetic Extended-Release Suspension for an extended period of time, do not suddenly stop taking Tussionex Pennkinetic Extended-Release Suspension without your doctor’s approval. If you suddenly stop taking Tussionex Pennkinetic Extended-Release Suspension, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping this medication.

Possible side effects of Tussionex Pennkinetic Extended-Release Suspension:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or pounding heartbeat; flushing or redness of face; severe drowsiness; shallow or very slow breathing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include agitation; coma; confusion; deep sleep or loss of consciousness; difficulty breathing; diminished mental alertness; hallucinations; hot or cold skin; large and unchanging pupils; sedation; seizures; shaking; sleeplessness; slowed breathing; slow heartbeat.

Proper storage of Tussionex Pennkinetic Extended-Release Suspension:

Store Tussionex Pennkinetic Extended-Release Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussionex Pennkinetic Extended-Release Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Tussionex Pennkinetic Extended-Release Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Tussionex Pennkinetic Extended-Release Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tussionex Pennkinetic Extended-Release Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Pseudoephedrine/Dextromethorphan (sue-do-eh-FED-rin/dex-troe-meth-OR-fan)
Brand Name: Examples include Dexatrex D and Tussin Pediatric

Tussin Pediatric Elixir is used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Tussin Pediatric Elixir is a decongestant and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, which helps you to breathe more easily. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Tussin Pediatric Elixir if:

• you are allergic to any ingredient in Tussin Pediatric Elixir
• you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
• you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tussin Pediatric Elixir:

Some medical conditions may interact with Tussin Pediatric Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
• if you have chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Tussin Pediatric Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Tussin Pediatric Elixir may be increased
• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
• Bromocriptine because the risk of side effects may be increased by Tussin Pediatric Elixir
• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Tussin Pediatric Elixir

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussin Pediatric Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tussin Pediatric Elixir:

Use Tussin Pediatric Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tussin Pediatric Elixir may be taken with or without food.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Tussin Pediatric Elixir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussin Pediatric Elixir.

Important safety information:

• Tussin Pediatric Elixir may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tussin Pediatric Elixir. Using Tussin Pediatric Elixir alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Do not take appetite suppressants while you are taking Tussin Pediatric Elixir without checking with your doctor.
• Tussin Pediatric Elixir contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
• Do NOT exceed the recommended dose or take Tussin Pediatric Elixir for longer than prescribed without checking with your doctor.
• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
• Tussin Pediatric Elixir may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Tussin Pediatric Elixir.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tussin Pediatric Elixir.
• Use Tussin Pediatric Elixir with caution in the ELDERLY because they may be more sensitive to its effects.
• Caution is advised when using Tussin Pediatric Elixir in CHILDREN because they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Tussin Pediatric Elixir, discuss with your doctor the benefits and risks of using Tussin Pediatric Elixir during pregnancy. It is unknown if Tussin Pediatric Elixir is excreted in breast milk. Do not breast-feed while taking Tussin Pediatric Elixir.

Possible side effects of Tussin Pediatric Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Tussin Pediatric Elixir:

Store Tussin Pediatric Elixir at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussin Pediatric Elixir out of the reach of children and away from pets.

General information:

• If you have any questions about Tussin Pediatric Elixir, please talk with your doctor, pharmacist, or other health care provider.
• Tussin Pediatric Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tussin Pediatric Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Dextromethorphan/Guaifenesin/Phenylephrine (dex-troe-meth-OR-fan/gwye-FEN-eh-sin/fen-ill-EF-rin)
Brand Name: Examples include Tussidex and Zotex

Tussidex Liquid is used for:

Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Tussidex Liquid is a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. It also works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Tussidex Liquid if:

• you are allergic to any ingredient in Tussidex Liquid
• you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
• you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tussidex Liquid:

Some medical conditions may interact with Tussidex Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
• if you have a chronic cough, lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Tussidex Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Tussidex Liquid may be increased
• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
• Bromocriptine because the risk of side effects may be increased by Tussidex Liquid
• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Tussidex Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussidex Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tussidex Liquid:

Use Tussidex Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tussidex Liquid may be taken with or without food.
• Drink plenty of water while taking Tussidex Liquid.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Tussidex Liquid, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussidex Liquid.

Important safety information:

• Tussidex Liquid may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tussidex Liquid. Using Tussidex Liquid alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
• Do not take appetite suppressants while you are taking Tussidex Liquid without checking with your doctor.
• Tussidex Liquid contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.
• Do NOT exceed the recommended dose or take Tussidex Liquid for longer than prescribed without checking with your doctor.
• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
• Tussidex Liquid may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Tussidex Liquid.
• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tussidex Liquid.
• Use Tussidex Liquid with caution in the ELDERLY because they may be more sensitive to its effects.
• Caution is advised when using Tussidex Liquid in CHILDREN because they may be more sensitive to its effects.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Tussidex Liquid, discuss with your doctor the benefits and risks of using Tussidex Liquid during pregnancy. It is unknown if Tussidex Liquid is excreted in breast milk. Do not breast-feed while taking Tussidex Liquid.

Possible side effects of Tussidex Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Tussidex Liquid:

Store Tussidex Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussidex Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Tussidex Liquid, please talk with your doctor, pharmacist, or other health care provider.
• Tussidex Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tussidex Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.