Generic Name: Benzoyl Peroxide (BEN-zoe-il per-OX-ide and SOE-dee-um HYE-al-ure-ON-ate)
Brand Name: Examples include Zacare 4% Kit and Zacare 8% Kit

Zacare 8% Kit Lotion is used for:

Treating mild to moderate acne.

Zacare 8% Kit Lotion is a kit. It contains an antibacterial and keratolytic medicine (benzoyl peroxide) along with a skin conditioning medicine (sodium hyaluronate). The benzoyl peroxide works to treat acne by killing certain bacteria on the skin and by causing a mild drying and peeling (keratolytic) effect. The sodium hyaluronate helps treat or prevent very dry or scaly skin.

Do NOT use Zacare 8% Kit Lotion if:

• you are allergic to any ingredient in Zacare 8% Kit Lotion

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zacare 8% Kit Lotion:

Some medical conditions may interact with Zacare 8% Kit Lotion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have inflamed or damaged skin at the application site

Some MEDICINES MAY INTERACT with Zacare 8% Kit Lotion. Because little, if any, of Zacare 8% Kit Lotion is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Zacare 8% Kit Lotion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zacare 8% Kit Lotion:

Use Zacare 8% Kit Lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use the benzoyl peroxide lotion: Wash the affected area with soap and water or as directed by your doctor. Shake the lotion well before each use. Wet the skin areas to be treated with water. Apply the lotion over the affected area. Gently rub it into a full lather. Rinse well with water then pat the area dry.
• To use the sodium hyaluronate gel: Apply to the affected areas and rub in well as directed by your doctor.
• Wash your hands immediately after using Zacare 8% Kit Lotion.
• If you miss a dose of Zacare 8% Kit Lotion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zacare 8% Kit Lotion.

Important safety information:

• Zacare 8% Kit Lotion is for external use only. Avoid getting it in your eyes, on the inside of your nose or mouth, or on your lips. If you get it in any of these areas, rinse right away with cool tap water.
• Do not apply Zacare 8% Kit Lotion to raw, inflamed, or irritated skin, including sunburns. Do not apply Zacare 8% Kit Lotion to open wounds.
• Several weeks may pass before you see improvement in your acne. It may take up to 8 to 12 weeks before you notice the full effect of Zacare 8% Kit Lotion. Continue to use Zacare 8% Kit Lotion for the full time recommended by your doctor. If your acne does not improve or if it gets worse, check with your doctor.
• Talk with your doctor before you use any other medicines, special cleansers, aftershave, or cosmetics on your skin.
• Zacare 8% Kit Lotion may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Zacare 8% Kit Lotion. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Benzoyl peroxide may cause bleaching. Avoid contact with hair, fabrics, or carpeting.
• Zacare 8% Kit Lotion should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zacare 8% Kit Lotion while you are pregnant. It is not known if Zacare 8% Kit Lotion is found in breast milk. If you are or will be breast-feeding while you use Zacare 8% Kit Lotion, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zacare 8% Kit Lotion:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild burning, dryness, itching, peeling, redness, stinging, or swelling of the treated areas.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; dizziness; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent burning, dryness, irritation, itching, peeling, redness, stinging, or swelling of the treated areas; shedding of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include excessive scaling; flushing; redness; swelling.

Proper storage of Zacare 8% Kit Lotion:

Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container, away from fire, flame, heat, and light. Keep Zacare 8% Kit Lotion out of the reach of children and away from pets.

General information:

• If you have any questions about Zacare 8% Kit Lotion, please talk with your doctor, pharmacist, or other health care provider.
• Zacare 8% Kit Lotion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Zacare 8% Kit Lotion. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Benzocaine/Pyrilamine/Zinc Oxide (BEN-zoe-kane/pir-IL-a-meen/zink OX-ide)
Brand Name: Z-Xtra

Z-Xtra is used for:

Temporarily relieving pain, itching, and swelling caused by minor skin irritation (eg, insect bites, minor rashes, eczema). It is also used to dry the oozing and weeping of poison ivy, poison oak, and poison sumac.

Z-Xtra is a topical anesthetic, antihistamine, and skin protectant combination. It works by numbing the skin and reducing swelling.

Do NOT use Z-Xtra if:

• you are allergic to any ingredient in Z-Xtra or to other topical anesthetics (eg, lidocaine)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Z-Xtra:

Some medical conditions may interact with Z-Xtra. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Z-Xtra. Because little, if any, of Z-Xtra is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Z-Xtra may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Z-Xtra:

Use Z-Xtra as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Shake well before each use.
• Cleanse area with mild soap and warm water when possible and rinse thoroughly. Gently dry by patting or blotting with tissue or a soft cloth.
• Apply Z-Xtra to the affected area and rub in gently as directed by your doctor or the package labeling.
• Do not apply Z-Xtra more often than 3 to 4 times daily.
• If you miss a dose of Z-Xtra, use it as soon as you remember. Continue to use it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Z-Xtra.

Important safety information:

• Z-Xtra is for external use only. Do not get it in your eyes, nose, or mouth. Do not get it in your vagina. If you get it in any of these areas, rinse at once with cool tap water.
• Do not use more than the recommended dose or use for longer than 7 days without checking with your doctor.
• If your symptoms do not get better within 7 days, if they get worse, or if they clear up and then come back, check with your doctor.
• Z-Xtra should not be used in CHILDREN younger than 12 years old without first checking with the child’s doctor; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Z-Xtra while you are pregnant. It is not known if Z-Xtra is found in breast milk after topical use. If you are or will be breast-feeding while you use Z-Xtra, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Z-Xtra:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Z-Xtra. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation at the application site.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Z-Xtra may be harmful if swallowed.

Proper storage of Z-Xtra:

Store Z-Xtra between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Keep Z-Xtra out of the reach of children and away from pets.

General information:

• If you have any questions about Z-Xtra, please talk with your doctor, pharmacist, or other health care provider.
• Z-Xtra is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Z-Xtra. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Benzoyl Peroxide (BEN-zoe-il per-OX-ide and SOE-dee-um HYE-al-ure-ON-ate)
Brand Name: Examples include Zacare 4% Kit and Zacare 8% Kit

Zacare 4% Kit Lotion is used for:

Treating mild to moderate acne.

Zacare 4% Kit Lotion is a kit. It contains an antibacterial and keratolytic medicine (benzoyl peroxide) along with a skin conditioning medicine (sodium hyaluronate). The benzoyl peroxide works to treat acne by killing certain bacteria on the skin and by causing a mild drying and peeling (keratolytic) effect. The sodium hyaluronate helps treat or prevent very dry or scaly skin.

Do NOT use Zacare 4% Kit Lotion if:

• you are allergic to any ingredient in Zacare 4% Kit Lotion

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zacare 4% Kit Lotion:

Some medical conditions may interact with Zacare 4% Kit Lotion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have inflamed or damaged skin at the application site

Some MEDICINES MAY INTERACT with Zacare 4% Kit Lotion. Because little, if any, of Zacare 4% Kit Lotion is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Zacare 4% Kit Lotion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Zacare 4% Kit Lotion:

Use Zacare 4% Kit Lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use the benzoyl peroxide lotion: Wash the affected area with soap and water or as directed by your doctor. Shake the lotion well before each use. Wet the skin areas to be treated with water. Apply the lotion over the affected area. Gently rub it into a full lather. Rinse well with water then pat the area dry.
• To use the sodium hyaluronate gel: Apply to the affected areas and rub in well as directed by your doctor.
• Wash your hands immediately after using Zacare 4% Kit Lotion.
• If you miss a dose of Zacare 4% Kit Lotion, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zacare 4% Kit Lotion.

Important safety information:

• Zacare 4% Kit Lotion is for external use only. Avoid getting it in your eyes, on the inside of your nose or mouth, or on your lips. If you get it in any of these areas, rinse right away with cool tap water.
• Do not apply Zacare 4% Kit Lotion to raw, inflamed, or irritated skin, including sunburns. Do not apply Zacare 4% Kit Lotion to open wounds.
• Several weeks may pass before you see improvement in your acne. It may take up to 8 to 12 weeks before you notice the full effect of Zacare 4% Kit Lotion. Continue to use Zacare 4% Kit Lotion for the full time recommended by your doctor. If your acne does not improve or if it gets worse, check with your doctor.
• Talk with your doctor before you use any other medicines, special cleansers, aftershave, or cosmetics on your skin.
• Zacare 4% Kit Lotion may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Zacare 4% Kit Lotion. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Benzoyl peroxide may cause bleaching. Avoid contact with hair, fabrics, or carpeting.
• Zacare 4% Kit Lotion should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zacare 4% Kit Lotion while you are pregnant. It is not known if Zacare 4% Kit Lotion is found in breast milk. If you are or will be breast-feeding while you use Zacare 4% Kit Lotion, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Zacare 4% Kit Lotion:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild burning, dryness, itching, peeling, redness, stinging, or swelling of the treated areas.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; dizziness; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent burning, dryness, irritation, itching, peeling, redness, stinging, or swelling of the treated areas; shedding of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include excessive scaling; flushing; redness; swelling.

Proper storage of Zacare 4% Kit Lotion:

Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container, away from fire, flame, heat, and light. Keep Zacare 4% Kit Lotion out of the reach of children and away from pets.

General information:

• If you have any questions about Zacare 4% Kit Lotion, please talk with your doctor, pharmacist, or other health care provider.
• Zacare 4% Kit Lotion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Zacare 4% Kit Lotion. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Dextromethorphan/Guaifenesin/Pseudoephedrine (DEX-troe-meth-OR-fan/gwye-FEN-e-sin/SOO-doe-e-FED-rin)
Brand Name: Z-COF 12

Z-COF 12 Suspension is used for:

Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Z-COF 12 Suspension is a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels, reducing swelling in the nasal passages, and loosening mucus and lung secretions in the chest, making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Z-COF 12 Suspension if:

• you are allergic to any ingredient in Z-COF 12 Suspension
• you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
• you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Z-COF 12 Suspension:

Some medical conditions may interact with Z-COF 12 Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of glaucoma, enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
• if you have a chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Z-COF 12 Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk Z-COF 12 Suspension’s side effects
• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
• Bromocriptine because the risk of its side effects may be increased by Z-COF 12 Suspension
• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Z-COF 12 Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Z-COF 12 Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Z-COF 12 Suspension:

Use Z-COF 12 Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Z-COF 12 Suspension by mouth with or without food.
• Shake well before each use.
• Take Z-COF 12 Suspension with a full glass of water (8 oz/240 mL).
• Drink plenty of water while taking Z-COF 12 Suspension.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Z-COF 12 Suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Z-COF 12 Suspension.

Important safety information:

• Z-COF 12 Suspension may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Z-COF 12 Suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not take appetite suppressants while you are taking Z-COF 12 Suspension without checking with your doctor.
• Z-COF 12 Suspension has pseudoephedrine and dextromethorphan in it. Before you start any new medicine, check the label to see if it has pseudoephedrine or dextromethorphan in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Do NOT exceed the recommended dose or take Z-COF 12 Suspension for longer than prescribed without checking with your doctor.
• If your symptoms do not improve within 7 days or if they become worse, check with your doctor.
• Do not use Z-COF 12 Suspension for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
• Z-COF 12 Suspension may interfere with certain lab tests. Be sure that your doctor and lab personnel know you are taking Z-COF 12 Suspension.
• Tell your doctor or dentist that you take Z-COF 12 Suspension before you receive any medical or dental care, emergency care, or surgery.
• Use Z-COF 12 Suspension with caution in the ELDERLY; they may be more sensitive to its effects.
• Z-COF 12 Suspension should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Z-COF 12 Suspension, contact your doctor. You will need to discuss the benefits and risks of using Z-COF 12 Suspension while you are pregnant. It is not known if Z-COF 12 Suspension is found in breast milk. Do not breast-feed while taking Z-COF 12 Suspension.

Possible side effects of Z-COF 12 Suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; excitability; headache; irritability; nausea; stomach upset; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast, slow, or irregular heartbeat; fever; hallucinations; seizures; severe or persistent dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Z-COF 12 Suspension:

Store Z-COF 12 Suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Z-COF 12 Suspension out of the reach of children and away from pets.

General information:

• If you have any questions about Z-COF 12 Suspension, please talk with your doctor, pharmacist, or other health care provider.
• Z-COF 12 Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Z-COF 12 Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Levocetirizine (LEE-voe-se-TIR-i-zeen)
Brand Name: Xyzal

Xyzal Solution is used for:

Treating allergy symptoms and chronic hives. It may also be used for other conditions as determined by your doctor.

Xyzal Solution is an antihistamine. It works by blocking a substance in the body called histamine. This helps to decrease allergy symptoms and hives.

Do NOT use Xyzal Solution if:

• you are allergic to any ingredient in Xyzal Solution or to cetirizine
• you have severe kidney problems or you are receiving dialysis
• the patient is a child 6 months to 11 years old who has kidney problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xyzal Solution:

Some medical conditions may interact with Xyzal Solution. Tell your doctor or pharmacist if you have any medical conditions, especially any of the following:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have kidney or liver problems

Some MEDICINES MAY INTERACT with Xyzal Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• Ritonavir or theophylline because they may increase the risk of Xyzal Solution’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xyzal Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xyzal Solution:

Use Xyzal Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Xyzal Solution by mouth with or without food. Take it in the evening unless your doctor tells you otherwise.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• If you miss a dose of Xyzal Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Xyzal Solution.

Important safety information:

• Xyzal Solution may cause drowsiness. This effect may be worse if you take it with alcohol or certain medicines. Use Xyzal Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Xyzal Solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• The risk of drowsiness may be greater if you take Xyzal Solution in high doses. Do NOT take more than the recommended dose without checking with your doctor.
• Use Xyzal Solution with caution in the ELDERLY; they may be more sensitive to its effects.
• Xyzal Solution should be used with extreme caution in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xyzal Solution while you are pregnant. Xyzal Solution is found in breast milk. Do not breast-feed while taking Xyzal Solution.

Possible side effects of Xyzal Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; drowsiness; dry mouth; sore throat; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); dark urine; fainting; fever; irregular heartbeat; mental or mood changes (eg, aggression, agitation); seizure; severe or persistent dizziness; shortness of breath; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include agitation; irritability; restlessness; severe drowsiness.

Proper storage of Xyzal Solution:

Store Xyzal Solution between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Xyzal Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Xyzal Solution, please talk with your doctor, pharmacist, or other health care provider.
• Xyzal Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xyzal Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Lidocaine/Hydrocortisone (LYE-doe-kane/HYE-droe-KOR-ti-sone/SIL-ee-um)
Brand Name: Xyralid RC

Xyralid RC Cream is used for:

Treating pain, itching, soreness, and discomfort caused by hemorrhoids or other anal conditions. It also helps to relieve constipation.

Xyralid RC Cream is a kit that contains an anesthetic and corticosteroid cream and a bulk-forming laxative. The anesthetic works by helping to decrease soreness and discomfort. The corticosteroid works by reducing swelling, redness, and itching. The bulk-forming laxative works by absorbing water in the intestines. This helps to soften and stool so it can be more easily passed.

Do NOT use Xyralid RC Cream if:

• you are allergic to any ingredient in Xyralid RC Cream or to similar medications (eg, dibucaine)
• you have a tuberculous or fungal skin infection, a herpes simplex skin infection, chickenpox, shingles, or a skin infection following smallpox vaccination

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xyralid RC Cream:

Some medical conditions may interact with Xyralid RC Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any anesthetic medicine
• if you have a history of thinning skin, skin infection, or other skin disorders
• if you have recently received a vaccination or if you have ever had a positive tuberculin (TB) skin test
• if you have stomach pain, nausea, vomiting, rectal bleeding, or trouble swallowing
• if you have liver problems, diabetes, high blood sugar levels, very poor health, stomach or bowel pain, nausea, or vomiting; or if you have had a sudden change in bowel habits persisting for more than 2 weeks

Some MEDICINES MAY INTERACT with Xyralid RC Cream. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Class IA antiarrhythmics (eg, disopyramide) because the risk of their side effects may be increased by Xyralid RC Cream

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xyralid RC Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xyralid RC Cream:

Use Xyralid RC Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use the rectal cream: Clean the affected area with the cleansing wipe as directed before you apply the cream. Attach the applicator to the tube of rectal cream and squeeze gently until a small amount of cream shows. Lubricate the tip of the applicator with the cream and apply as directed by your doctor.
• To use the bulk-forming laxative: Mix the contents of the packet with fluid in the shaker cup provided. Take the laxative with plenty of fluid according to the directions provided or as directed by your doctor.
• If you miss a dose of Xyralid RC Cream, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xyralid RC Cream.

Important safety information:

• Do not get Xyralid RC Cream in your eyes, ears, nose, or mouth. If you get it in any of these areas, rinse at once with cool tap water.
• If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
• Do NOT use more than the recommended dose, use more often, or use for longer than prescribed without checking with your doctor.
• If you use topical products too often, your condition may become worse.
• Xyralid RC Cream may cause a numbing effect at the application site. Do not scratch, rub, or expose the area to extreme hot or cold temperature until the numbness is gone.
• Xyralid RC Cream has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Do not take additional laxatives or stool softeners with Xyralid RC Cream unless directed by your doctor.
• Tell your doctor if you fail to have a bowel movement even after using Xyralid RC Cream.
• Taking the bulk-forming laxative without enough liquid may cause it to swell and block your throat or esophagus and may cause choking. If you experience chest pain, vomiting, or difficulty swallowing or breathing after taking the laxative, seek immediate medical attention.
• Tell your doctor or dentist that you take Xyralid RC Cream before you receive any medical or dental care, emergency care, or surgery.
• Use Xyralid RC Cream with caution in the ELDERLY; they may be more sensitive to its effects.
• Xyralid RC Cream should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is not known if Xyralid RC Cream can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xyralid RC Cream while you are pregnant. It is not known if Xyralid RC Cream is found in breast milk after topical use. If you are or will be breast-feeding while you use Xyralid RC Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xyralid RC Cream:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal fullness; mild stinging, burning, redness, or discoloration at the application site; minor bloating.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty swallowing; excessive irritation; rectal bleeding; skin infection (eg, redness, swelling, pus discharge); vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Xyralid RC Cream may be harmful if swallowed.

Proper storage of Xyralid RC Cream:

Store Xyralid RC Cream at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat and light. Do not store in the bathroom. Protect from freezing. Keep Xyralid RC Cream out of the reach of children and away from pets.

General information:

• If you have any questions about Xyralid RC Cream, please talk with your doctor, pharmacist, or other health care provider.
• Xyralid RC Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xyralid RC Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Xylometazoline (ZYE-loe-me-TAZ-oh-leen)
Brand Name: 4-Way Moisturizing Relief

Xylometazoline Spray is used for:

Relieving nasal congestion due to the common cold, hay fever, other upper respiratory tract allergies, or sinus infection. It also soothes nasal discomfort caused by dryness. It may also be used to treat other conditions as determined by your doctor.

Xylometazoline Spray is a decongestant. It works by shrinking swollen and congested nasal tissues (mucous membranes) by constricting blood vessels. This results in relief of congestion (stuffy feeling), improved drainage of mucus, and improved breathing through the nose. Local application (eg, nose drops and sprays) causes more intense and rapid vasoconstriction than oral medicines (eg, tablets, syrups).

Do NOT use Xylometazoline Spray if:

• you are allergic to any ingredient in Xylometazoline Spray

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xylometazoline Spray:

Some medical conditions may interact with Xylometazoline Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of high blood pressure, enlarged prostate or trouble urinating, diabetes, overactive thyroid, or heart disease

Some MEDICINES MAY INTERACT with Xylometazoline Spray. However, no specific interactions with Xylometazoline Spray are known at this time.

Ask your health care provider if Xylometazoline Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xylometazoline Spray:

Use Xylometazoline Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use a nose spray, gently blow your nose. Sit down and tilt your head back slightly. Place the tip of the spray container into the nose. Using a finger from your other hand, press against the opposite nostril to close it off. Breathe gently through the open nostril and squeeze the spray container. If you are using more than 1 spray, wait for 1 to 2 minutes between sprays. After using the medicine, rinse the tip of the spray unit in hot water and dry with a clean tissue to prevent contamination.
• If you miss a dose of Xylometazoline Spray and are using it regularly, use it as soon as possible. If it is much more than 1 hour since your missed dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xylometazoline Spray.

Important safety information:

• Do not use Xylometazoline Spray for more than 3 days unless advised to do so by your health care provider. Frequent or long-term use of Xylometazoline Spray may cause nasal congestion to recur or worsen.
• Diabetes patients – Xylometazoline Spray may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Xylometazoline Spray should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xylometazoline Spray while you are pregnant. It is not known if Xylometazoline Spray is found in breast milk. If you are or will be breast-feeding while you use Xylometazoline Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xylometazoline Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Increase in nasal discharge; temporary burning, stinging or sneezing.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; nervousness; severe or persistent headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Xylometazoline Spray:

Store Xylometazoline Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Xylometazoline Spray out of the reach of children and away from pets.

General information:

• If you have any questions about Xylometazoline Spray, please talk with your doctor, pharmacist, or other health care provider.
• Xylometazoline Spray is to be used only by the patient for whom it is prescribed. Do not share it with other due to increased risk of spreading infection.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xylometazoline Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Lidocaine (LIE-doe-cane)
Brand Name: Xylocaine Viscous

Xylocaine Viscous Solution is used for:

Temporarily relieving pain of the mouth and throat. It is also used to reduce gagging during certain dental procedures or for other conditions as determined by your doctor.

Xylocaine Viscous Solution is a local anesthetic. It works by preventing nerves from transmitting painful impulses to the brain.

Do NOT use Xylocaine Viscous Solution if:

• you are allergic to any ingredient in Xylocaine Viscous Solution or other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xylocaine Viscous Solution:

Some medical conditions may interact with Xylocaine Viscous Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a blood infection or severe injury of the mouth or throat
• if you have heart, liver, or kidney problems
• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any anesthetic medicine

Some MEDICINES MAY INTERACT with Xylocaine Viscous Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, beta-adrenergic blockers (eg, metoprolol), cimetidine, or mexiletine because side effects, such as confusion, dizziness, lightheadedness, or tiredness, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xylocaine Viscous Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xylocaine Viscous Solution:

Use Xylocaine Viscous Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Depending on the condition being treated, you may need to swish Xylocaine Viscous Solution around the mouth and spit it out, gargle and swallow it, or apply it to the affected area with a cotton-tipped applicator. Carefully follow the directions provided by your doctor for using Xylocaine Viscous Solution.
• Do not get Xylocaine Viscous Solution in your eyes.
• If you miss a dose of Xylocaine Viscous Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xylocaine Viscous Solution.

Important safety information:

• Xylocaine Viscous Solution may cause drowsiness, dizziness, blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Xylocaine Viscous Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Tell your doctor or dentist that you take Xylocaine Viscous Solution before you receive any medical or dental care, emergency care, or surgery.
• Xylocaine Viscous Solution may make it difficult for you to swallow. Do not eat anything for at least 1 hour after Xylocaine Viscous Solution has been applied in the mouth or throat area.
• Numbness of the tongue may cause you to bite the inside of your mouth accidentally. Do not eat any food or chew gum while your mouth or throat area is numb.
• Xylocaine Viscous Solution may cause a numbing effect at the application site. Do not scratch, rub, or expose the area to extreme hot or cold temperature until the numbness is gone.
• Do not use more medicine, apply it more often, or use it for longer than prescribed. Your condition will not improve faster, but the risk of side effects may be increased.
• PREGNANCY and BREAST-FEEDING: It is not known if Xylocaine Viscous Solution can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xylocaine Viscous Solution while you are pregnant. Xylocaine Viscous Solution is found in breast milk. If you are or will be breast-feeding while you use Xylocaine Viscous Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xylocaine Viscous Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness or swelling at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); choking; confusion; dizziness or lightheadedness; fast breathing; fast, slow, or irregular heartbeat; fever; mood or mental changes; ringing in the ears or hearing changes; seizures; shortness of breath; swelling of the throat; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include apprehension; blurred vision; confusion; difficulty breathing; nervousness; ringing in the ears; seizures; sensations of heat, cold, or numbness; severe dizziness, drowsiness, or lightheadedness; slow or irregular heartbeat; tremor; twitching; unconsciousness; vomiting.

Proper storage of Xylocaine Viscous Solution:

Store Xylocaine Viscous Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Keep Xylocaine Viscous Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Xylocaine Viscous Solution, please talk with your doctor, pharmacist, or other health care provider.
• Xylocaine Viscous Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xylocaine Viscous Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Lidocaine (LIE-doe-cane)
Brand Name: Xylocaine Jelly

Xylocaine Jelly Gel is used for:

Decreasing pain and discomfort resulting from urinary tract procedures or the placement of endotracheal (airway) tubes. It may also be used for other conditions as determined by your doctor.

Xylocaine Jelly Gel is an anesthetic. It works by preventing nerves from transmitting painful impulses to the brain.

Do NOT use Xylocaine Jelly Gel if:

• you are allergic to any ingredient in Xylocaine Jelly Gel or to other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xylocaine Jelly Gel:

Some medical conditions may interact with Xylocaine Jelly Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a blood infection; severe injury of the area where Xylocaine Jelly Gel is to be applied; or heart, liver, or kidney problems

Some MEDICINES MAY INTERACT with Xylocaine Jelly Gel. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, beta-adrenergic blockers (eg, metoprolol), cimetidine, or mexiletine because side effects, such as confusion, dizziness, lightheadedness or tiredness, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xylocaine Jelly Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xylocaine Jelly Gel:

Use Xylocaine Jelly Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Do not get Xylocaine Jelly Gel in your eyes.
• If you miss a dose of Xylocaine Jelly Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xylocaine Jelly Gel.

Important safety information:

• Xylocaine Jelly Gel may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Xylocaine Jelly Gel with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Tell your doctor or dentist that you take Xylocaine Jelly Gel before you receive any medical or dental care, emergency care, or surgery.
• Xylocaine Jelly Gel may make it difficult for you to swallow. Do not eat anything for at least 1 hour after Xylocaine Jelly Gel has been applied in the mouth or throat area.
• Numbness of the tongue may cause you to bite the inside of your mouth accidentally. Do not eat any food or chew gum while your mouth or throat area is numb.
• PREGNANCY and BREAST-FEEDING: It is not known if Xylocaine Jelly Gel can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xylocaine Jelly Gel while you are pregnant. It is not known if Xylocaine Jelly Gel is found in breast milk after topical use. If you are or will be breast-feeding while you use Xylocaine Jelly Gel, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xylocaine Jelly Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness or swelling at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); choking; confusion; dizziness or lightheadedness; fast breathing; fast, slow, or irregular heartbeat; fever; mood or mental changes; ringing in the ears or hearing changes; seizures; shortness of breath; swelling of the throat; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include apprehension; blurred vision; confusion; difficulty breathing; nervousness; ringing in the ears; seizures; sensations of heat, cold, or numbness; severe dizziness, drowsiness, or lightheadedness; slow or irregular heartbeat; tremor; twitching; unconsciousness; vomiting.

Proper storage of Xylocaine Jelly Gel:

Store Xylocaine Jelly Gel at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Keep Xylocaine Jelly Gel out of the reach of children and away from pets.

General information:

• If you have any questions about Xylocaine Jelly Gel, please talk with your doctor, pharmacist, or other health care provider.
• Xylocaine Jelly Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xylocaine Jelly Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: Lidocaine (LIE-doe-cane)
Brand Name: Xylocaine

Xylocaine Solution is used for:

Temporarily relieving pain of the mouth, throat, or nose, and certain parts of the digestive tract. It may also be used for other conditions as determined by your doctor.

Xylocaine Solution is a local anesthetic. It works by preventing nerves from transmitting painful impulses to the brain.

Do NOT use Xylocaine Solution if:

• you are allergic to any ingredient in Xylocaine Solution or other similar medicines (eg, amide-type anesthetics)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xylocaine Solution:

Some medical conditions may interact with Xylocaine Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a blood infection or severe injury of the mouth or throat
• if you have heart, liver, or kidney problems
• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to any anesthetic medicine

Some MEDICINES MAY INTERACT with Xylocaine Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, beta-adrenergic blockers (eg, metoprolol), cimetidine, or mexiletine because side effects, such as confusion, dizziness, lightheadedness, or tiredness, may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xylocaine Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xylocaine Solution:

Use Xylocaine Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Depending on the condition being treated, you may need to swish Xylocaine Solution around the mouth and spit it out, gargle and swallow it, or apply it to the affected area with a cotton-tipped applicator. Carefully follow the directions provided by your doctor for using Xylocaine Solution.
• Do not get Xylocaine Solution in your eyes.
• If you miss a dose of Xylocaine Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Xylocaine Solution.

Important safety information:

• Xylocaine Solution may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Xylocaine Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Tell your doctor or dentist that you take Xylocaine Solution before you receive any medical or dental care, emergency care, or surgery.
• Xylocaine Solution may make it difficult for you to swallow. Do not eat anything for at least 1 hour after Xylocaine Solution has been applied in the mouth or throat area.
• Numbness of the tongue may cause you to bite the inside of your mouth accidentally. Do not eat any food or chew gum while your mouth or throat area is numb.
• Xylocaine Solution may cause a numbing effect at the application site. Do not scratch, rub, or expose the area to extreme hot or cold temperature until the numbness is gone.
• Do not use more medicine, apply it more often, or use it for longer than prescribed. Your condition will not improve faster, but the risk of side effects may be increased.
• PREGNANCY and BREAST-FEEDING: It is not known if Xylocaine Solution can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xylocaine Solution while you are pregnant. Xylocaine Solution is found in breast milk. If you are or will be breast-feeding while you use Xylocaine Solution, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Xylocaine Solution:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Redness or swelling at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); choking; confusion; dizziness or lightheadedness; fast breathing; fast, slow, or irregular heartbeat; fever; mood or mental changes; ringing in the ears or hearing changes; seizures; shortness of breath; swelling of the throat; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include apprehension; blurred vision; confusion; difficulty breathing; nervousness; ringing in the ears; seizures; sensations of heat, cold, or numbness; severe dizziness, drowsiness, or lightheadedness; slow or irregular heartbeat; tremor; twitching; unconsciousness; vomiting.

Proper storage of Xylocaine Solution:

Store Xylocaine Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Keep Xylocaine Solution out of the reach of children and away from pets.

General information:

• If you have any questions about Xylocaine Solution, please talk with your doctor, pharmacist, or other health care provider.
• Xylocaine Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xylocaine Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.