Generic Name: Diphenhydramine (DYE-fen-HYE-dra-meen)
Brand Name: Examples include Nytol and Simply Sleep

Nytol is used for:

Treating occasional sleeplessness and reducing difficulty falling asleep.

Nytol is an antihistamine. It works by depressing the central nervous system (brain) to produce drowsiness.

Do NOT use Nytol if:

• you are allergic to any ingredient in Nytol or to other similar medicines
• you are taking sodium oxybate (GHB)
• you are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nytol:

Some medical conditions may interact with Nytol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema, lung disease, shortness of breath, or sleep apnea
• if you have blockage of the stomach, intestine, or urinary tract; difficulty urinating; diabetes; ulcers; enlargement of the prostate; glaucoma; heart disease; high blood pressure; the blood disease porphyria; or thyroid disease

Some MEDICINES MAY INTERACT with Nytol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nytol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nytol:

Use Nytol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Nytol by mouth with or without food.
• Use Nytol exactly as directed on the package, unless instructed differently by your doctor.
• Take at least 30 minutes before bedtime to help fall asleep.
• If you miss a dose of Nytol and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nytol.

Important safety information:

• Nytol may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Nytol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Nytol; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Nytol may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Nytol may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Nytol. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Nytol has diphenhydramine in it. Before you start any new medicine, check the label to see if it has diphenhydramine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• If sleeplessness persists for more than 2 weeks, contact your health care provider.
• Use Nytol with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, sedation, and lightheadedness upon standing.
• Nytol should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nytol while you are pregnant. Nytol is found in breast milk. Do not breast-feed while taking Nytol.

Possible side effects of Nytol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; dry mouth, throat, and nose; thickening of mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; decreased alertness; excitability; fast heartbeat; hallucinations; tightness or pounding in the chest; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; excitement; hallucinations; loss of consciousness; muscle twitching; seizures; tremor; weakness.

Proper storage of Nytol:

Store Nytol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), or according to directions on the package label. Store in the original package or container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nytol out of the reach of children and away from pets.

General information:

• If you have any questions about Nytol, please talk with your doctor, pharmacist, or other health care provider.
• Nytol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nytol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: diphenhydramine (DYE fen HYE dra meen)
Brand Names: Aler-Tab, Allergy, Allermax, Altaryl, Benadryl Allergy, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Children’s Allergy, Diphen Cough, Diphenhist, Dytuss, PediaCare Children’s Allergy, Q-Dryl, Q-Dryl A/F, Siladryl, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep-ettes, Sleep-ettes D, Sominex Maximum Strength Caplet, Theraflu Thin Strips Multi Symptom, Triaminic Thin Strips Cough & Runny Nose, Unisom Sleepgels Maximum Strength, Valu-Dryl

What is Nytol Caplet (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson’s disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Nytol Caplet (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Nytol Caplet (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• glaucoma or increased pressure in the eye;

• a stomach ulcer;

• an enlarged prostate, bladder problems or difficulty urinating;

• an overactive thyroid (hyperthyroidism);

• hypertension or any type of heart problems; or

• asthma.

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Nytol Caplet (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Nytol Caplet (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Nytol Caplet (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

• sleepiness, fatigue, or dizziness;

• headache;

• dry mouth; or

• difficulty urinating or an enlarged prostate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nytol Caplet (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

• medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

• any other medications that make you feel drowsy, sleepy, or relaxed.

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 5.01. Revision Date: 04/02/2009 3:16:39 PM.

Generic Name: doxylamine (dox IL a meen)
Brand Names: Aldex AN, Nytol Maximum Strength, Unisom

What is Nytol Maximum Strength (doxylamine)?

Doxylamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Doxylamine is sometimes combined with other medicines to treat sneezing, itching, watery eyes, and runny nose caused by allergies or the common cold.

Doxylamine as a single drug (not part of a combination) is used as a short-term treatment for sleep problems (insomnia).

Doxylamine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Nytol Maximum Strength (doxylamine)?

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.

Ask a doctor or pharmacist about taking this medication if you have glaucoma, kidney disease, an enlarged prostate, problems with urination, a stomach ulcer or obstruction, or a chronic lung disease such as bronchitis or emphysema.

If you miss a dose, take it as soon as you remember. It is best to take doxylamine only when you can devote several hours to sleep. If it is almost your normal waking hour, skip the missed dose and wait until you are ready for bed again. Do not use extra medicine to make up the missed dose.

There may be other drugs that can interact with doxylamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Avoid drinking alcohol while you are taking this medication. It can add to drowsiness caused by an antihistamine.

What should I discuss with my health care provider before taking Nytol Maximum Strength (doxylamine)?

Do not take this medication if you are allergic to doxylamine or other antihistamines.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:

• glaucoma;

• kidney disease;

• an enlarged prostate;

• problems with urination;

• stomach ulcer or digestive tract obstruction; or

• bronchitis, emphysema or other chronic lung disease.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 12 years old without the advice of a doctor.

How should I take Nytol Maximum Strength (doxylamine)?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with food or milk if it upsets your stomach.

The chewable tablet must be chewed thoroughly before you swallow it.

To treat insomnia, doxylamine is usually taken within 30 minutes of bedtime. Follow your doctor’s instructions.

Talk with your doctor if your sleep problems do not improve after 2 weeks of treatment.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store doxylamine at room temperature away from moisture and heat.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember. It is best to take doxylamine only when you can devote several hours to sleep. If it is almost your normal waking hour, skip the missed dose and wait until you are ready for bed again. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness, loss of coordination, dry mouth, or seizure (convulsions).

What should I avoid while taking Nytol Maximum Strength (doxylamine)?

Do not use any other over-the-counter cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much antihistamine. Read the label of any other medicine you are using to see if it contains an antihistamine such as doxylamine, chlorpheniramine or diphenhydramine. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid becoming overheated or dehydrated during exercise and in hot weather.

Avoid drinking alcohol while you are taking this medication. Alcohol can add to drowsiness caused by an antihistamine.

Nytol Maximum Strength (doxylamine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heartbeat;

• confusion, hallucinations, unusual thoughts or behavior;

• severe dizziness, anxiety, restless feeling, or nervousness;

• urinating less than usual or not at all;

• easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

Less serious side effects may include:

• blurred vision;

• dry mouth;

• nausea, stomach pain, constipation;

• dizziness, drowsiness;

• problems with memory or concentration;

• ringing in your ears;

• restless or excitability (especially in children);

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nytol Maximum Strength (doxylamine)?

Cold or allergy medicine, narcotic pain medicine, other sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by doxylamine. Tell your doctor if you need to use any of these other medicines while you are taking doxylamine.

Tell your doctor about all other medications you use, especially:

• a diuretic (water pill);

• diphenhydramine (Benadryl) applied to the skin as a spray, cream, lotion, gel, or stick;

• bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

• medication to treat irritable bowel syndrome;

• bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);

• aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others); or

• other antihistamines, or medicine to treat motion sickness.

This list is not complete and there may be other drugs that can interact with doxylamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about doxylamine.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.03. Revision Date: 11/19/2009 11:37:37 AM.

Brand names: Myco-Triacet II, Mytrex, Mycolog-II

Why is Nystatin, Triamcinolone acetonide prescribed?

Mycolog-II Cream and Ointment are prescribed for the treatment of candidiasis (a yeast-like fungal infection) of the skin. The combination of an antifungal (nystatin) and a steroid (triamcinolone acetonide) provides greater benefit than nystatin alone during the first few days of treatment. Nystatin kills the fungus or prevents its growth; triamcinolone helps relieve the redness, swelling, itching, and other discomfort that can accompany a skin infection.

Most important fact about Nystatin, Triamcinolone acetonide

Absorption of Nystatin, Triamcinolone acetonide through the skin can affect the whole body instead of just the surface of the skin being treated. Although unusual, it is possible that you could experience symptoms of steroid excess such as weight gain, reddening and rounding of the face and neck, growth of excess body and facial hair, high blood pressure, emotional disturbances, increased blood sugar, and urinary excretion of glucose (marked by an increase in frequency of urination).

Use of Nystatin, Triamcinolone acetonide over large surface areas, for prolonged periods, or with airtight dressings or bandages, could cause these problems. Your doctor will watch your condition and periodically check for symptoms.

How should you take Nystatin, Triamcinolone acetonide?

Use this medicine for the full course of treatment, even if your symptoms are gone. Apply a thin layer to the affected area and gently rub it in. Do not bandage or wrap the area being treated, unless your doctor tells you to. Keep the area cool and dry.

Use Nystatin, Triamcinolone acetonide exactly as prescribed by your doctor. Do not use it more often or for a longer time. It is for external use only. Avoid contact with the eyes.

• If you miss a dose…
  Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.

• Storage instructions…
  Store away from heat and light. Do not freeze.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Mycolog-II.

• Side effects may include:
  Blistering, burning, dryness, eruptions resembling acne, excessive discoloring of the skin, excessive growth of hair (especially on the face), hair loss (especially on the scalp), inflammation around the mouth, inflammation of hair follicles, irritation, itching, peeling, prickly heat, reddish purple lines on skin, secondary infection, severe inflammation of the skin, softening of the skin, stretch marks, stretching or thinning of the skin

Why should Nystatin, Triamcinolone acetonide not be prescribed?

If you are sensitive to or have ever had an allergic reaction to nystatin, triamcinolone acetonide, or other antifungals or steroids, you should not take Nystatin, Triamcinolone acetonide. Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Nystatin, Triamcinolone acetonide

Do not use Nystatin, Triamcinolone acetonide for any disorder other than the one for which it was prescribed.

Remember to avoid wrapping or bandaging the affected area. The use of tight-fitting diapers or plastic pants is not recommended for a child being treated in the diaper area with Mycolog-II. These garments may act in the same way as airtight dressings or bandages.

If an irritation or allergic reaction develops while using Mycolog-II, notify your doctor.

If used in the groin area, apply Mycolog-II sparingly and wear loose-fitting clothing.

If your condition does not show improvement after 2 to 3 weeks, or if it gets worse, consult your doctor.

Possible food and drug interactions when taking Nystatin, Triamcinolone acetonide

No interactions have been reported.

Special information if you are pregnant or breastfeeding

The effects of Mycolog-II in pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor before using Mycolog-II.

It is not known whether Nystatin, Triamcinolone acetonide appears in breast milk. If Nystatin, Triamcinolone acetonide is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Nystatin, Triamcinolone acetonide is finished.

Recommended dosage for Nystatin, Triamcinolone acetonide

ADULTS

Mycolog-II Cream

Mycolog-II Cream is usually applied to the affected areas 2 times a day, in the morning and evening, by gently and thoroughly massaging the preparation into the skin. Your doctor will have you stop using the cream if your symptoms persist after 25 days of treatment.

Mycolog-II Ointment

A thin film of Mycolog-II Ointment is usually applied to the affected areas 2 times a day, in the morning and the evening. Your doctor will have you stop using the ointment if your symptoms persist after 25 days of treatment.

CHILDREN

Your doctor will limit use of Mycolog-II for children to the least amount that is effective. Long-term treatment may interfere with the growth and development of children.

Overdosage

An acute overdosage is unlikely with the use of Mycolog-II; however, long-term or prolonged use can produce reactions throughout the body. See “Most important fact about Nystatin, Triamcinolone acetonide.”

Nystatin/

Triamcinolone

Generic Name: Nystatin/Triamcinolone (nye-STAT-in/trye-am-SIN-oh-lone)
Brand Name: Examples include Mycolog II and Mycogen II

Nystatin/Triamcinolone is used for:

Treating or preventing fungal infections of the skin.

Nystatin/Triamcinolone is an antifungal and steroid combination. It works by stopping fungus growth and reducing inflammation.

Do NOT use Nystatin/Triamcinolone if:

• you are allergic to any ingredient in Nystatin/Triamcinolone
• you are taking mifepristone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nystatin/Triamcinolone:

Some medical conditions may interact with Nystatin/Triamcinolone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have measles, had a positive skin tuberculin skin test, tuberculosis (TB), chickenpox, shingles, or wasting of the skin (skin atrophy)
• if you have had a vaccination with an inactivated or live vaccine

Some MEDICINES MAY INTERACT with Nystatin/Triamcinolone. Because little, if any, of Nystatin/Triamcinolone is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Nystatin/Triamcinolone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nystatin/Triamcinolone:

Use Nystatin/Triamcinolone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To prevent reinfection, wash your hands thoroughly before and after using Nystatin/Triamcinolone.
• Wash and completely dry the affected area. Gently rub the medicine in until it is evenly distributed. Do not bandage, cover, or wrap the treated skin unless directed to do so by your doctor.
• Nystatin/Triamcinolone works best if used at the same time each day.
• To clear up your infection completely, use Nystatin/Triamcinolone for the full course of treatment. Keep using it even if you feel better in a few days.
• Nystatin/Triamcinolone is for external use only. Do not get it your eyes.
• If you miss a dose of Nystatin/Triamcinolone, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Nystatin/Triamcinolone.

Important safety information:

• If Nystatin/Triamcinolone is to be applied to the groin area, apply sparingly and wear loose-fitting clothing. If Nystatin/Triamcinolone is to be applied to skin covered by a diaper, do not use tight-fitting diapers or plastic pants.
• Nystatin/Triamcinolone should not be used if irritation occurs or if symptoms worsen or have not improved within 25 days of use.
• Nystatin/Triamcinolone should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nystatin/Triamcinolone while you are pregnant. It is unknown if Nystatin/Triamcinolone is found in breast milk. If you are or will be breast-feeding while you use Nystatin/Triamcinolone, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Nystatin/Triamcinolone:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; burning; cracking and stinging of the skin; dryness; excessive hair growth; inflamed skin around the mouth; inflammation of hair follicles; irritation; itching; loss of skin color; secondary infection; skin wasting; streaking of skin.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Nystatin/Triamcinolone may be harmful if swallowed.

Proper storage of Nystatin/Triamcinolone:

Store Nystatin/Triamcinolone at controlled room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not freeze. Keep Nystatin/Triamcinolone out of the reach of children and away from pets.

General information:

• If you have any questions about Nystatin/Triamcinolone, please talk with your doctor, pharmacist, or other health care provider.
• Nystatin/Triamcinolone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nystatin/Triamcinolone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Pronunciation: (nye-STAT-in/TRY-am-SIN-oh-lone ah-SEE-toe-nide)
Class: Corticosteroid, Antifungal combination

Trade Names:
Nystatin/Triamcinolone Acetonide
- Cream 100,000 units/g nystatin, 0.1% triamcinolone
- Ointment 100,000 units/g nystatin, 0.1% triamcinolone

Pharmacology

The antifungal binds to fungal cell membrane, changing membrane permeability and allowing leakage of intracellular components; the corticosteroid adds anti-inflammatory, antipruritic, and vasoconstrictive action.

Indications and Usage

Cutaneous candidiasis.

Contraindications

Standard considerations.

Dosage and Administration

Adults and Children

Topical Apply as a thin film to affected area(s) twice daily.

General Advice

• For topical use only. Not for ophthalmic or otic use.

Storage/Stability

Store at controlled room temperature (59° to 86°F).

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

Dermatologic

Acneiform eruptions; burning; itching; irritation; dryness; folliculitis; hypertrichosis; hypopigmentation; perioral dermatitis; allergic contact dermatitis; maceration; secondary infection; skin atrophy; striae; miliaria.

Precautions

Pregnancy

Category C .

Lactation

Undetermined.

Children

Greater risk of HPA axis suppression, Cushing syndrome, intracranial hypertension.

Risk of HPA axis suppression, Cushing syndrome, hyperglycemia, glycosuria

Conditions that augment cutaneous absorption include use of large body surface area, prolonged use, and occlusive dressings.

Patient Information

• Review prescribed dosing schedule with patient or caregiver.
• Remind patient or caregiver that medicine is not to be used in the eye or ear.
• Teach patient or caregiver proper technique for applying medicine: wash hands; apply thin film to affected area(s) using fingers or applicator. Wash hands after application.
• Caution patient or caregiver not to occlude treated skin area with bandage, cover, or wrap.
• Advise patient or caregiver to contact health care provider if local redness or swelling develops, or if skin lesions do not improve or worsen.

Copyright © 2009 Wolters Kluwer Health.

Generic Name: nystatin topical (nye STAT in)
Brand Names: Mycostatin Topical, Nystop, Pedi-Dri

What is Nystop (nystatin topical)?

Nystatin topical is an antifungal medication. Nystatin topical prevents fungus from growing on your skin.

Nystatin topical is used to treat skin infections caused by yeast.

Nystatin topical may also be used for other purposes not those listed in this medication guide.

What is the most important information I should know about Nystop (nystatin topical)?

Avoid getting this medication in your eyes, nose, or mouth. If it does get into these areas, rinse thoroughly with water.

Do not cover treated skin areas with bandages or dressings that do not allow air circulation unless your doctor has told you to. You may use a light gauze dressing to keep the medication from getting on your clothes or bed sheets.

Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse within 7 days of using nystatin topical.

What should I discuss with my healthcare provider before using Nystop (nystatin topical)?

You should not use nystatin topical if you have had an allergic reaction to it in the past.

It is not known whether nystatin topical will harm an unborn baby. Do not use nystatin topical without telling your doctor if you are pregnant. It is not known whether nystatin topical passes into breast milk or if it could harm a nursing baby. Do not use nystatin topical without telling your doctor if you are breast-feeding a baby.

How should I use Nystop (nystatin topical)?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after using this medication.

Clean and dry the skin before you apply nystatin topical.

Do not cover treated skin areas with bandages or dressings that do not allow air circulation unless your doctor has told you to. You may use a light gauze dressing to keep the medication from getting on your clothes or bed sheets.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse within 7 days of using nystatin topical. Store nystatin topical at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of topically applied nystatin is not likely to cause life-threatening symptoms.

What should I avoid while using Nystop (nystatin topical)?

Avoid getting this medication in your eyes, nose, or mouth. If it does get into these areas, rinse thoroughly with water.

Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed.

Nystop (nystatin topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop nystatin topical and call your doctor at once if you have severe itching, redness, peeling, dryness, blistering, or irritation of your treated skin.

Less serious side effects may include mild skin itching, redness, or irritation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nystop (nystatin topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied nystatin. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about nystatin topical.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.06. Revision Date: 4/12/2009 4:39:20 PM.

Generic Name: Nystatin (nye-STAT-in)
Brand Name: Nystop

Nystop Powder is used for:

Treating certain fungal infections. It may also be used for other conditions as determined by your doctor.

Nystop Powder is an antifungal. It works by killing sensitive fungi.

Do NOT use Nystop Powder if:

• you are allergic to any ingredient in Nystop Powder

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nystop Powder:

Some medical conditions may interact with Nystop Powder. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Nystop Powder. However, no specific interactions with Nystop Powder are known at this time.

Ask your health care provider if Nystop Powder may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nystop Powder:

Use Nystop Powder as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Clean the affected area with soap and water and dry thoroughly. Sprinkle enough powder to cover the affected area.
• If Nystop Powder is used on the feet, sprinkle Nystop Powder freely on the feet and in shoes and socks.
• Do not cover with a bandage or dressing unless directed otherwise by your doctor.
• Wash your hands immediately after using Nystop Powder.
• To clear up your infection completely, use Nystop Powder for the full course of treatment. Keep using it even if you feel better in a few days.
• Nystop Powder works best if it is used at the same times each day.
• If you miss a dose of Nystop Powder, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Nystop Powder.

Important safety information:

• Nystop Powder is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in your eyes, rinse them right away with cool tap water.
• Be sure to use Nystop Powder for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nystop Powder while you are pregnant. It is not known if Nystop Powder is found in breast milk. If you are or will be breast-feeding while you use Nystop Powder, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Nystop Powder:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Nystop Powder. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); burning, pain, or irritation of the affected area.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Nystop Powder may be harmful if swallowed.

Proper storage of Nystop Powder:

Store Nystop Powder at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Avoid temperatures above 104 degrees F (40 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nystop Powder out of the reach of children and away from pets.

General information:

• If you have any questions about Nystop Powder, please talk with your doctor, pharmacist, or other health care provider.
• Nystop Powder is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nystop Powder. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: nystatin topical (nye STAT in)
Brand Names: Mycostatin Topical, Nystop, Pedi-Dri

What is nystatin topical?

Nystatin topical is an antifungal medication. Nystatin topical prevents fungus from growing on your skin.

Nystatin topical is used to treat skin infections caused by yeast.

Nystatin topical may also be used for other purposes not those listed in this medication guide.

What is the most important information I should know about nystatin topical?

Avoid getting this medication in your eyes, nose, or mouth. If it does get into these areas, rinse thoroughly with water.

Do not cover treated skin areas with bandages or dressings that do not allow air circulation unless your doctor has told you to. You may use a light gauze dressing to keep the medication from getting on your clothes or bed sheets.

Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse within 7 days of using nystatin topical.

What should I discuss with my healthcare provider before using nystatin topical?

You should not use nystatin topical if you have had an allergic reaction to it in the past.

It is not known whether nystatin topical will harm an unborn baby. Do not use nystatin topical without telling your doctor if you are pregnant. It is not known whether nystatin topical passes into breast milk or if it could harm a nursing baby. Do not use nystatin topical without telling your doctor if you are breast-feeding a baby.

How should I use nystatin topical?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Wash your hands before and after using this medication.

Clean and dry the skin before you apply nystatin topical.

Do not cover treated skin areas with bandages or dressings that do not allow air circulation unless your doctor has told you to. You may use a light gauze dressing to keep the medication from getting on your clothes or bed sheets.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Call your doctor if your symptoms do not improve, or if they get worse within 7 days of using nystatin topical. Store nystatin topical at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of topically applied nystatin is not likely to cause life-threatening symptoms.

What should I avoid while using nystatin topical?

Avoid getting this medication in your eyes, nose, or mouth. If it does get into these areas, rinse thoroughly with water.

Avoid wearing tight-fitting, synthetic clothing (such as nylon) that doesn’t allow air circulation. Wear clothing made of loose cotton and other natural fibers until your infection is healed.

Nystatin topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop nystatin topical and call your doctor at once if you have severe itching, redness, peeling, dryness, blistering, or irritation of your treated skin.

Less serious side effects may include mild skin itching, redness, or irritation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Nystatin topical Dosing Information

Usual Adult Dose for Oral Thrush:

1 to 2 oral lozenges (200,000 to 400,000 units) 4 to 5 times a day or
500,000 units of oral suspension 4 times a day.

Usual Adult Dose for Intestinal Candidiasis:

500,000 to 1,000,000 units orally 3 times a day.

Usual Pediatric Dose for Oral Thrush:

Neonates: 100,000 units of oral suspension 4 times a day.
>1 m <12 m:: 200,000 units of oral suspension 4 times a day.
>=1 year <18 years: 1 to 2 oral lozenges (200,000 to 400,000 units) 4 to 5 times a day or 500,000 units of oral suspension 4 times a day.

What other drugs will affect nystatin topical?

It is not likely that other drugs you take orally or inject will have an effect on topically applied nystatin. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about nystatin topical.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.06. Revision Date: 4/12/2009 4:39:20 PM.