Nucynta

30/06/10

Generic Name: tapentadol (ta PEN ta dol)
Brand Names: Nucynta

What is tapentadol?

Tapentadol is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Tapentadol is used to treat moderate to severe pain.

Tapentadol may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about tapentadol?

You should not use this medication if you are allergic to tapentadol, or if you have severe liver or kidney disease, if you are having an asthma attack, or if you have a bowel obstruction called paralytic ileus. Do not take tapentadol if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take tapentadol before the MAO inhibitor has cleared from your body. Tapentadol may be habit-forming and should be used only by the person it was prescribed for. Tapentadol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not drink alcohol while you are taking tapentadol. Dangerous side effects or death can occur when alcohol is combined with a narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol.

Never take more tapentadol than is prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Tapentadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not stop using tapentadol suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

What should I discuss with my healthcare provider before taking tapentadol?

You should not use this medication if you are allergic to tapentadol, or if you have severe liver or kidney disease, if you are having an asthma attack, or if you have a bowel obstruction called paralytic ileus. Do not take tapentadol if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take tapentadol before the MAO inhibitor has cleared from your body.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

  • asthma, COPD, sleep apnea, or other breathing disorders;

  • liver or kidney disease;
  • curvature of the spine;

  • a history of head injury or brain tumor;

  • epilepsy or other seizure disorder;

  • gallbladder disease or pancreas problems;

  • mental illness; or

  • a history of drug or alcohol addiction.

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Tapentadol may cause breathing problems and addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Tapentadol can pass into breast milk and may harm a nursing baby. Do not breast-feed while taking this medication.

Older adults may be more sensitive to the effects of this medicine.

Do not give tapentadol to a child. Tapentadol may be habit-forming and should be used only by the person it was prescribed for. Tapentadol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.


How should I take tapentadol?

Take this medication exactly as it was prescribed for you. Never take tapentadol in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Your doctor may occasionally change the timing of your dose to make sure you get the best results from this medication.

Take this medicine with a full glass of water.

You may take tapentadol with or without food.

Tapentadol can cause constipation. Talk to your doctor before using a laxative or stool softener to treat or prevent this side effect.

Do not stop using tapentadol suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Store tapentadol at room temperature away from moisture and heat.

Keep track of how many tablets have been used from each new bottle of this medicine. Tapentadol is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription. Ask a pharmacist about how to dispose of any unused pills after you have stopped taking tapentadol.

Never crush a tablet or other pill to mix into a liquid for snorting tapentadol or injecting the drug into your vein. This practice has resulted in death with the misuse of narcotic pain medicines and similar prescription drugs.

What happens if I miss a dose?

Since tapentadol is sometimes used as needed, you may not be on a dosing schedule. If you are using the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of tapentadol can be fatal.

Overdose symptoms may include extreme drowsiness, blurred vision, confusion, vomiting, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.

What should I avoid while taking tapentadol?

Do not drink alcohol while you are using tapentadol. Dangerous side effects or death can occur when alcohol is combined with tapentadol. Check your food and medicine labels to be sure these products do not contain alcohol. Tapentadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Tapentadol side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • weak or shallow breathing, weak pulse, slow heartbeat;

  • seizure (convulsions);

  • severe drowsiness or dizziness;

  • confusion, problems with speech or balance; or

  • agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

Less serious side effects may include:

  • mild nausea or vomiting;

  • constipation;

  • mild dizziness, drowsiness;

  • dry mouth;

  • itching; or

  • increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect tapentadol?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tapentadol. Tell your doctor if you regularly use any of these medicines, or any other narcotic pain medicines.

This list is not complete and there may be other drugs that can interact with tapentadol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about tapentadol.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 07/31/2009 8:38:28 AM.

 

Generic Name: codeine, guaifenesin, and pseudoephedrine (KOE deen, gwye FEN e sin, and soo doe e FED rin)
Brand Names: Ambifed CD, Ambifed CDX, Ambifed-G CD, Ambifed-G CDX, Biotussin DAC, Cheratussin DAC, Codafed, Codahistine Expectorant, Halotussin DAC, Maxifed CD, Medent C, Phenhist Expectorant

What is Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Codeine is a narcotic cough suppressant.

Guaifenesin is an expectorant. It helps loosen mucus congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of codeine, guaifenesin, and pseudoephedrine is used to treat stuffy nose and cough, and to reduce chest congestion caused by the common cold, infections, or allergies.

Codeine, guaifenesin, and pseudoephedrine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains guaifenesin or pseudoephedrine. Codeine may be habit-forming and should be used only by the person it was prescribed for. Codeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

What should I discuss with my healthcare provider before taking Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. You should not take codeine, guaifenesin, and pseudoephedrine if you have ever had an allergic reaction to it, or if you have:

  • severe or uncontrolled high blood pressure;

  • severe coronary artery disease; or

  • if you are breast-feeding a baby.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking codeine, guaifenesin, and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

  • heart disease or high blood pressure;

  • ischemic heart disease (reduced circulation of blood to the heart);

  • asthma, COPD, sleep apnea, or other breathing disorders;

  • diabetes;

  • a thyroid disorder;

  • glaucoma;

  • liver or kidney disease;
  • a history of head injury or brain tumor;

  • epilepsy or other seizure disorder;

  • enlarged prostate, urination problems;

  • a stomach or intestinal disorder;

  • Addison’s disease or other adrenal gland disorders;

  • if you have recently had surgery on your stomach, intestines, kidney, or bladder.

  • gallbladder disease;

  • mental illness; or

  • a history of drug or alcohol addiction.

If you have any of these conditions, you may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Codeine can cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication if you are breast-feeding a baby. Codeine may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Older adults may be more likely to have side effects from this medication.


How should I take Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Take this medication exactly as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Take codeine, guaifenesin, and pseudoephedrine with food if it upsets your stomach. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your cough does not improve after 5 days of treatment, or if you also have a fever.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medicine at room temperature, away from heat, light, and moisture.

Keep track of how much of this medication has been used. Codeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of codeine can be fatal.

Overdose symptoms may include nausea, vomiting, feeling restless or nervous, extreme dizziness or drowsiness, confusion, cold and clammy skin, shallow breathing, slow heart rate, pinpoint pupils, fainting, or coma.

What should I avoid while taking Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not drink alcohol while you are taking this medication. Alcohol can increase some of the side effects of codeine. Do not use any other over-the-counter cold, allergy, or cough medicine without first asking your doctor or pharmacist. Guaifenesin and pseudoephedrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains guaifenesin or pseudoephedrine. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). This medication can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;

  • slow heart rate, weak pulse, fainting, weak or shallow breathing;

  • severe dizziness, anxiety, restless feeling, or nervousness, headache, tremors;

  • confusion, unusual thoughts or behavior;

  • seizure (convulsions);

  • urinating less than usual or not at all; or

  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

Less serious side effects include:

  • dizziness or headache;

  • constipation;

  • nausea, vomiting, upset stomach, loss of appetite;

  • feeling excited or restless;

  • sleep problems (insomnia);

  • increased sweating;

  • warmth, tingling, or redness under your skin; or

  • mild skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nucochem Pediatric Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine or guaifenesin.

Also tell your doctor if you are using any of the following drugs:

  • medicines to treat high blood pressure;

  • indomethacin (Indocin);

  • methyldopa (Aldomet); or

  • a beta-blocker such as atenolol (Tenormin), metoprolol (Lopressor, Toprol), propranolol (Inderal), sotalol (Betapace), and others.

This list is not complete and there may be other drugs that can interact with codeine, guaifenesin, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about codeine, guaifenesin, and pseudoephedrine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.08. Revision Date: 11/19/2009 2:15:02 PM.

 

Nucofed Syrup

30/06/10

Generic Name: Codeine/Guaifenesin/Pseudoephedrine (KOE-deen/gwye-FEN-e-sin/SOO-doe-e-FED-rin)
Brand Name: Examples include Mytussin DAC and Robitussin DAC

Nucofed Syrup is used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Nucofed Syrup is a decongestant, cough suppressant, and expectorant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough. The expectorant loosens mucus and lung secretions in the chest and makes coughs more productive.

Do NOT use Nucofed Syrup if:

  • you are allergic to any ingredient in Nucofed Syrup or any other codeine- or morphine-related medicine (eg, oxycodone)
  • you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
  • you are having an asthma attack
  • you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nucofed Syrup:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to morphine, codeine, or any other opiate (eg, hydrocodone, dihydrocodeine, oxycodone)
  • if you have a history of glaucoma; an enlarged prostate gland or other prostate problems; heart problems; diabetes; high blood pressure; blood vessel problems; stroke; liver or kidney problems; blockage of the stomach, bowel, or bladder; adrenal gland problems; or thyroid problems
  • if you have a history of constipation, stomach problems (eg, ulcers), bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent stomach, bowel, or urinary surgery
  • if you have breathing or lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if you have a cough that occurs with large amounts of mucus
  • if you have a fever, severe drowsiness, recent head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, or a seizure disorder (eg, epilepsy)
  • if you have very poor health or a history of alcohol abuse, other substance abuse, or suicidal thoughts or actions
  • if you are taking medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with Nucofed Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), cimetidine, furazolidone, HIV protease inhibitors (eg, ritonavir), indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Nucofed Syrup’s side effects
  • Naltrexone, quinidine, or rifamycins (eg, rifampin) because they may decrease Nucofed Syrup’s effectiveness
  • Bromocriptine or sodium oxybate (GHB) because the risk of their side effects may be increased by Nucofed Syrup
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Nucofed Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nucofed Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.



How to use Nucofed Syrup:

  • Take Nucofed Syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Drink plenty of water while taking Nucofed Syrup.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Nucofed Syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nucofed Syrup.

Important safety information:

  • Nucofed Syrup may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Nucofed Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Nucofed Syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Nucofed Syrup may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do not take diet or appetite control medicines while you are taking Nucofed Syrup without checking with your doctor.
  • Nucofed Syrup has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 5 days, if they get worse, or if they go away and then come back, check with your doctor.
  • If your symptoms occur along with fever, rash, or persistent headache, contact your doctor.
  • Do not use Nucofed Syrup for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Nucofed Syrup may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Nucofed Syrup. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Nucofed Syrup may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Nucofed Syrup.
  • Tell your doctor or dentist that you take Nucofed Syrup before you receive any medical or dental care, emergency care, or surgery.
  • Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Use Nucofed Syrup with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, low blood pressure, excitability, dry mouth, and trouble urinating.
  • Caution is advised when using Nucofed Syrup in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Nucofed Syrup should not be used in CHILDREN younger than 6 years old without first checking with the child’s doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nucofed Syrup while you are pregnant. Nucofed Syrup is found in breast milk. Do not breast-feed while taking Nucofed Syrup.

Possible side effects of Nucofed Syrup:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; confusion; difficulty urinating; fainting; fast, slow, or irregular heartbeat; hallucinations; mental or mood changes; persistent trouble sleeping; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow breathing; tremor; uncontrolled muscle movement.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shallow or rapid breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Nucofed Syrup:

Store Nucofed Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nucofed Syrup out of the reach of children and away from pets.

General information:

  • If you have any questions about Nucofed Syrup, please talk with your doctor, pharmacist, or other health care provider.
  • Nucofed Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nucofed Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010
Database Edition 10.2.1.002
Copyright © 2010 Wolters Kluwer Health, Inc.
 

Nucofed

30/06/10

Generic Name: Codeine/Pseudoephedrine (KOE-deen/soo-doe-eh-FED-rin)
Brand Name: Nucofed

Nucofed is used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Nucofed is a decongestant and cough suppressant. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use Nucofed if:

  • you are allergic to any ingredient in Nucofed or any other codeine or morphine related medicine (eg, oxycodone)
  • you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
  • you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nucofed:

Some medical conditions may interact with Nucofed. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to morphine, codeine, or any other opiate (eg, hydrocodone, dihydrocodeine, oxycodone)
  • if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, stroke, adrenal gland problems, or an overactive thyroid
  • if you have a history of stomach problems, bowel problems (eg, chronic inflammation or ulceration of the bowel), or gallbladder problems (eg, gallstones), or if you have had recent abdominal surgery
  • if you have breathing or lung problems (eg, asthma, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
  • if you have or recently had any head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures
  • if you have a history of alcohol or substance abuse or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Nucofed. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), cimetidine, COMT inhibitors (eg, tolcapone), furazolidone, HIV protease inhibitors (eg, ritonavir), indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Nucofed may be increased
  • Digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, seizures, irregular heartbeat, or heart attack may be increased
  • Naltrexone and quinidine because the effectiveness of Nucofed may be decreased.
  • Bromocriptine because the risk of side effects may be increased by Nucofed
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Nucofed

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nucofed may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.



How to use Nucofed:

Use Nucofed as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Nucofed may be taken with or without food.
  • If you miss a dose of Nucofed, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nucofed.

Important safety information:

  • Nucofed may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Nucofed. Using Nucofed alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not take appetite suppressants while you are taking Nucofed without checking with your doctor.
  • Nucofed contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take Nucofed for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
  • Nucofed may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Nucofed.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Nucofed.
  • Use Nucofed with caution in the ELDERLY because they may be more sensitive to its effects.
  • Caution is advised when using Nucofed in CHILDREN because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Nucofed, discuss with your doctor the benefits and risks of using Nucofed during pregnancy. It is unknown if Nucofed is excreted in breast milk. Do not breast-feed while taking Nucofed.

Possible side effects of Nucofed:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Nucofed:

Store Nucofed at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nucofed out of the reach of children and away from pets.

General information:

  • If you have any questions about Nucofed, please talk with your doctor, pharmacist, or other health care provider.
  • Nucofed is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nucofed. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010
Database Edition 10.2.1.002
Copyright © 2010 Wolters Kluwer Health, Inc.
 

Nucofed Liquid

30/06/10

Generic Name: Pseudoephedrine/Codeine (SOO-doe-e-FED-rin/KOE-deen)
Brand Name: Examples include Notuss-DC and Nucofed

Nucofed Liquid is used for:

Relieving nasal congestion and cough due to colds, flu, or allergies. It may also be used for other conditions as determined by your doctor.

Nucofed Liquid is a decongestant and narcotic cough suppressant. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The cough suppressant works in the brain to help decrease the cough reflex, which reduces a dry cough.

Do NOT use Nucofed Liquid if:

  • you are allergic to any ingredient in Nucofed Liquid or any other codeine or morphine related medicine (eg, oxycodone)
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nucofed Liquid:

Some medical conditions may interact with Nucofed Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to morphine, codeine, or any other opiate (eg, dihydrocodeine, hydrocodone, oxycodone)
  • if you have a history of glaucoma or increased pressure in the eye, prostate problems (eg, enlarged prostate gland), heart problems, diabetes, high blood pressure, blood vessel problems, stroke, adrenal gland problems, liver problems, or thyroid problems, or if you have trouble urinating
  • if you have a history of stomach or bowel problems (eg, constipation, inflammation, ulcer), severe diarrhea caused by antibiotic use, or gallbladder problems (eg, gallstones), or if you have had recent stomach or bowel surgery
  • if you have breathing or lung problems (eg, asthma, chronic bronchitis, emphysema, shortness of breath), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
  • if you are dehydrated, very overweight, or have a condition that causes severe drowsiness
  • if you have a head or brain injury, brain tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures, or if you have recently had any of these conditions
  • if you have a history of alcohol or substance abuse, mental or mood problems, or suicidal thoughts or behavior

Some MEDICINES MAY INTERACT with Nucofed Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin, droxidopa, or sodium oxybate (GHB) because the risk of severe drowsiness, breathing problems, irregular heartbeat, or heart attack may be increased
  • Beta-blockers (eg, propranolol), cimetidine, COMT inhibitors (eg, tolcapone), furazolidone, HIV protease inhibitors (eg, ritonavir), indomethacin, MAOIs (eg, phenelzine), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk Nucofed Liquid’s side effects
  • Naltrexone, quinidine, or rifampin because they may decrease Nucofed Liquid’s effectiveness
  • Bromocriptine because the risk of its side effects may be increased by Nucofed Liquid
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Nucofed Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nucofed Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.



How to use Nucofed Liquid:

Use Nucofed Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Nucofed Liquid by mouth with or without food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you have trouble sleeping from Nucofed Liquid, try not to take it within a few hours before bedtime. This may help to decrease sleeplessness caused by Nucofed Liquid.
  • If you miss a dose of Nucofed Liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nucofed Liquid.

Important safety information:

  • Nucofed Liquid may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Nucofed Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Nucofed Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not take diet or appetite control medicines while you are taking Nucofed Liquid without checking with your doctor.
  • Nucofed Liquid has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your cough or other symptoms persist for more than 7 days, if they come back, or if you also have fever, rash, or persistent headache, check with your doctor.
  • Do not use Nucofed Liquid for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Nucofed Liquid may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Nucofed Liquid.
  • Tell your doctor or dentist that you take Nucofed Liquid before you receive any medical or dental care, emergency care, or surgery.
  • Use Nucofed Liquid with caution in the ELDERLY; they may be more sensitive to its effects.
  • Nucofed Liquid should not be used in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Nucofed Liquid, discuss with your doctor the benefits and risks of using Nucofed Liquid during pregnancy. Nucofed Liquid is found in breast milk. Do not breast-feed while taking Nucofed Liquid.

When used for long periods of time or at high doses, Nucofed Liquid may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Nucofed Liquid stops working well. Do not take more than prescribed.

When used for long periods of time or at high doses, some people develop a need to continue taking Nucofed Liquid. This is known as DEPENDENCE or addiction.

If you suddenly stop taking Nucofed Liquid, you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea; vomiting; pain; rigid muscles; rapid heartbeat; seeing, hearing or feeling things that are not there; shivering or tremors; sweating; trouble sleeping.

Possible side effects of Nucofed Liquid:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; stomach pain; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; difficulty urinating; fast, slow, or irregular heartbeat; hallucinations; loss of coordination; mental or mood changes; numbness or tingling of the skin; persistent loss of appetite; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; shortness of breath; tremor; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest pain; cold, clammy skin; confusion; fast, slow, or irregular heartbeat; hallucinations; pinpoint pupils; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; slow or difficult breathing; vomiting.

Proper storage of Nucofed Liquid:

Store Nucofed Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nucofed Liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about Nucofed Liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Nucofed Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nucofed Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010
Database Edition 10.2.1.002
Copyright © 2010 Wolters Kluwer Health, Inc.
 

Nubain

30/06/10

Generic Name: nalbuphine (NAL bue feen)
Brand Names: Nubain

What is Nubain (nalbuphine)?

Nalbuphine is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Nalbuphine is used to treat moderate to severe pain. It is also used for treating pain just after surgery or childbirth.

Nalbuphine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Nubain (nalbuphine)?

Nalbuphine may be habit-forming and should be used only by the person it was prescribed for. Nalbuphine should never be shared with another person, especially someone who has a history of drug abuse or addiction.

Nalbuphine may cause unpleasant side effects if you are already taking other narcotic pain medicines. Before you receive nalbuphine, tell your doctor about all other pain medicines you have recently used.

Also tell your doctor if you are allergic to any drugs, or if you have asthma or other breathing disorder, liver or kidney disease, gallbladder disease, mental illness, or a history of drug or alcohol addiction.

Tell your doctor if you take other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or any other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Nalbuphine may cause unpleasant side effects if you are already taking other narcotic pain medicines. Before you receive nalbuphine, tell your doctor about all other pain medicines you have recently used.

What should I discuss with my healthcare provider before I receive Nubain (nalbuphine)?

You should not receive this medication if you are allergic to nalbuphine.

Nalbuphine may cause unpleasant side effects if you are already taking other narcotic pain medicines. Before you receive nalbuphine, tell your doctor about all other pain medicines you have recently used.

Nalbuphine may be habit-forming and should be used only by the person it was prescribed for. Nalbuphine should never be shared with another person, especially someone who has a history of drug abuse or addiction.

Before receiving nalbuphine, tell your doctor if you are allergic to any drugs, or if you have:

  • asthma, COPD (chronic obstructive pulmonary disease), or other breathing disorder;

  • liver or kidney disease;
  • a history of head injury or brain tumor;

  • gallbladder disease;

  • mental illness; or

  • a history of drug or alcohol addiction.

FDA pregnancy category B. Nalbuphine is not expected to be harmful to an unborn baby. However, do not receive this medication without telling your doctor if you are pregnant. Nalbuphine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is nalbuphine given?

This medication is given as an injection into a muscle or under your skin, or through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.

Nalbuphine is usually given every 3 to 6 hours.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

You should not stop using nalbuphine suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

What happens if I miss a dose?

Since nalbuphine is usually given by a healthcare provider, it is not likely that you will miss a dose.


What happens if I overdose?

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include drowsiness and confusion.

What should I avoid while receiving Nubain (nalbuphine)?

Do not drink alcohol while you are using this medication. Alcohol can increase some of the side effects of nalbuphine. Nalbuphine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Nubain (nalbuphine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have any of these serious side effects:

  • weak or shallow breathing;

  • fast or slow heart rate;

  • cold, clammy skin;

  • confusion, hallucinations, unusual thoughts or behavior;

  • severe weakness or dizziness; or

  • feeling like you might pass out.

Less serious side effects are more likely to occur, such as:

  • warmth, tingling, or redness under your skin;

  • nausea, vomiting,, stomach cramps;

  • dizziness, spinning sensation;

  • dry mouth, unpleasant taste;

  • sweating;

  • itching or burning sensation;

  • headache; or

  • trouble with speech or vision.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nubain (nalbuphine)?

Tell your doctor if you take other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or any other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.

Other narcotic medications include fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin), hydromorphone (Dilaudid, Palladone), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (OxyContin), oxymorphone (Numorphan, Opana), and others.

Nalbuphine may cause unpleasant side effects if you are already taking other narcotic pain medicines. Before you receive nalbuphine, tell your doctor about all other pain medicines you have recently used.

This list is not complete and there may be other drugs that can interact with nalbuphine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about nalbuphine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:38:26 PM.

 

Nu-Iron

30/06/10

Generic Name: iron polysaccharide (I ern paw lee SACK ah ride)
Brand Names: Ezfe, Ferrex-150, Ferus Pic-150, Niferex, Niferex Elixir, Nu-Iron 150, Poly Iron, Polysaccharide Iron

What is Nu-Iron (iron polysaccharide)?

Iron polysaccharide is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood.

Iron polysaccharide is used as a dietary supplement, and to prevent and to treat iron deficiencies and iron deficiency anemia.

Iron polysaccharide may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Nu-Iron (iron polysaccharide)?

Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.

Who should not take Nu-Iron (iron polysaccharide)?

Do not take iron polysaccharide if you have

  • hemochromatosis,

  • hemosiderosis, or

  • hemolytic anemia.

Iron polysaccharide may be dangerous if you have any of the conditions listed above.

If you do not have an iron deficiency, talk to your doctor about the use of iron polysaccharide. Generally, iron polysaccharide should not be taken chronically by individuals with a normal iron balance.

Talk to your doctor before taking iron polysaccharide if you are pregnant. Talk to your doctor before taking iron polysaccharide if you are breast-feeding a baby.


How should I take Nu-Iron (iron polysaccharide)?

Take iron polysaccharide exactly as directed by your doctor, or as directed on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each tablet with a full glass of water. Shake the suspension well before measuring a dose. To ensure you get the correct dose, use a dose-measuring cup or spoon, not a regular table spoon to measure the dose. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Mix the liquid forms of iron polysaccharide with water, juice, or another beverage as directed and drink the mixture through a straw to prevent staining of the teeth.

Take iron polysaccharide on an empty stomach for best results. If stomach upset occurs, take iron polysaccharide with food or following a meal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.

Store iron polysaccharide at room temperature, away from moisture and heat. Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time to take the next dose, skip the dose you missed and take the next regularly scheduled dose as directed. Do not take a double dose.


What happens if I overdose?

Seek emergency medical attention.

Symptoms of a iron polysaccharide overdose include decreased energy; nausea; vomiting; abdominal pain; tarry stools; a weak, rapid pulse; fever; coma; seizures; and death.

What should I avoid while taking Nu-Iron (iron polysaccharide)?

Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.


Nu-Iron (iron polysaccharide) side effects

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking iron polysaccharide and seek emergency medical attention.

Other less serious side effects are more likely to occur. Continue taking iron polysaccharide and talk to your doctor or pharmacist if you experience

  • stomach upset,

  • nausea or vomiting,

  • constipation,

  • diarrhea,

  • black or darker than normal appearing stools, or

  • temporary staining of the teeth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nu-Iron (iron polysaccharide)?

Do not take iron polysaccharide within 2 hours of a dose of any of the following medicines

  • a tetracycline antibiotic such as tetracycline (Achromycin, Sumycin), minocycline (Minocin, Dynacin), doxycycline (Vibramycin, Monodox), demeclocycline (Declomycin), oxytetracycline (Terramycin), or troleandomycin (TAO);

  • a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), enoxacin (Penetrex) ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), sparfloxacin (Zagam), or trovafloxacin (Trovan);

  • levodopa (Larodopa, Dopar, Sinemet);

  • levothyroxine (Synthroid, Levoxyl, others);

  • methyldopa (Aldomet); or

  • penicillamine (Cuprimine).

Iron polysaccharide may decrease the absorption of the drugs listed above.

Do not take antacids within 2 hours of a dose of iron polysaccharide. Antacids may decrease the absorption of iron polysaccharide.

Drugs other than those listed here may also interact with iron polysaccharide. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines while taking iron polysaccharide.

Where can I get more information?

  • Your pharmacist can provide more information about iron polysaccharide.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.09. Revision Date: 4/12/2009 4:41:50 PM.

 

Nu-Iron 150

30/06/10

Generic Name: iron polysaccharide (I ern paw lee SACK ah ride)
Brand Names: Ezfe, Ferrex-150, Ferus Pic-150, Niferex, Niferex Elixir, Nu-Iron 150, Poly Iron, Polysaccharide Iron

What is Nu-Iron 150 (iron polysaccharide)?

Iron polysaccharide is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood.

Iron polysaccharide is used as a dietary supplement, and to prevent and to treat iron deficiencies and iron deficiency anemia.

Iron polysaccharide may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Nu-Iron 150 (iron polysaccharide)?

Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.

Who should not take Nu-Iron 150 (iron polysaccharide)?

Do not take iron polysaccharide if you have

  • hemochromatosis,

  • hemosiderosis, or

  • hemolytic anemia.

Iron polysaccharide may be dangerous if you have any of the conditions listed above.

If you do not have an iron deficiency, talk to your doctor about the use of iron polysaccharide. Generally, iron polysaccharide should not be taken chronically by individuals with a normal iron balance.

Talk to your doctor before taking iron polysaccharide if you are pregnant. Talk to your doctor before taking iron polysaccharide if you are breast-feeding a baby.


How should I take Nu-Iron 150 (iron polysaccharide)?

Take iron polysaccharide exactly as directed by your doctor, or as directed on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each tablet with a full glass of water. Shake the suspension well before measuring a dose. To ensure you get the correct dose, use a dose-measuring cup or spoon, not a regular table spoon to measure the dose. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Mix the liquid forms of iron polysaccharide with water, juice, or another beverage as directed and drink the mixture through a straw to prevent staining of the teeth.

Take iron polysaccharide on an empty stomach for best results. If stomach upset occurs, take iron polysaccharide with food or following a meal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.

Store iron polysaccharide at room temperature, away from moisture and heat. Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time to take the next dose, skip the dose you missed and take the next regularly scheduled dose as directed. Do not take a double dose.


What happens if I overdose?

Seek emergency medical attention.

Symptoms of a iron polysaccharide overdose include decreased energy; nausea; vomiting; abdominal pain; tarry stools; a weak, rapid pulse; fever; coma; seizures; and death.

What should I avoid while taking Nu-Iron 150 (iron polysaccharide)?

Keep this medication out of the reach of children. An accidental overdose of iron by a child can be fatal.

Iron polysaccharide may decrease the absorption of other medicines. Talk to your doctor and pharmacist before taking iron polysaccharide if you take any other prescription or over-the-counter medicines.


Nu-Iron 150 (iron polysaccharide) side effects

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking iron polysaccharide and seek emergency medical attention.

Other less serious side effects are more likely to occur. Continue taking iron polysaccharide and talk to your doctor or pharmacist if you experience

  • stomach upset,

  • nausea or vomiting,

  • constipation,

  • diarrhea,

  • black or darker than normal appearing stools, or

  • temporary staining of the teeth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nu-Iron 150 (iron polysaccharide)?

Do not take iron polysaccharide within 2 hours of a dose of any of the following medicines

  • a tetracycline antibiotic such as tetracycline (Achromycin, Sumycin), minocycline (Minocin, Dynacin), doxycycline (Vibramycin, Monodox), demeclocycline (Declomycin), oxytetracycline (Terramycin), or troleandomycin (TAO);

  • a fluoroquinolone antibiotic such as ciprofloxacin (Cipro), enoxacin (Penetrex) ofloxacin (Floxin), norfloxacin (Noroxin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), grepafloxacin (Raxar), sparfloxacin (Zagam), or trovafloxacin (Trovan);

  • levodopa (Larodopa, Dopar, Sinemet);

  • levothyroxine (Synthroid, Levoxyl, others);

  • methyldopa (Aldomet); or

  • penicillamine (Cuprimine).

Iron polysaccharide may decrease the absorption of the drugs listed above.

Do not take antacids within 2 hours of a dose of iron polysaccharide. Antacids may decrease the absorption of iron polysaccharide.

Drugs other than those listed here may also interact with iron polysaccharide. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines while taking iron polysaccharide.

Where can I get more information?

  • Your pharmacist can provide more information about iron polysaccharide.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.09. Revision Date: 4/12/2009 4:41:50 PM.

 

Nu-Iron Plus

30/06/10

Generic Name: multivitamin with iron (MUL tee VYE ta mins with i ron)
Brand Names:

What is Nu-Iron Plus (multivitamin with iron)?

Multivitamin are a combination of many different vitamins that are normally found in foods and other natural sources.

Iron is normally found in foods like red meat. In the body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Multivitamin and iron are used to provide vitamins and iron that are not taken in through the diet. They are also used to treat iron or vitamin deficiencies caused by illness, pregnancy, poor nutrition, digestive disorders, and many other conditions.

Multivitamin and iron may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Nu-Iron Plus (multivitamin with iron)?

Never take more than the recommended dose of a multivitamin. Avoid taking any other multivitamin product within 2 hours before or after you take multivitamin with iron. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects. Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects. Iron and other minerals contained in a multivitamin can also cause serious overdose symptoms if you take too much.

Overdose symptoms may include severe stomach pain, vomiting, bloody diarrhea, coughing up blood, constipation, loss of appetite, hair loss, peeling skin, warmth or tingly feeling, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine or stools, black and tarry stools, pale skin, easy bruising or bleeding, weakness, shallow breathing, weak and rapid pulse, pale skin, blue lips, and seizure (convulsions).

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin with iron.

What should I discuss with my healthcare provider before taking Nu-Iron Plus (multivitamin with iron)?

Iron and certain vitamins can cause serious or life-threatening side effects if taken in large doses. Do not take more of this medication than directed on the label or prescribed by your doctor.

If you have any medical conditions, ask your doctor before taking a multivitamin with iron. If you have certain conditions, you may need a certain vitamin formulation or special tests while taking this product.

Do not take multivitamin with iron without telling your doctor if you are pregnant or plan to become pregnant. Some vitamins and minerals can harm an unborn baby if taken in large doses. You may need to use a prenatal vitamin specially formulated for pregnant women. Multivitamin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.


How should I take Nu-Iron Plus (multivitamin with iron)?

Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.

Never take more than the recommended dose of multivitamin with iron. Avoid taking any other multivitamin product within 2 hours before or after you take multivitamin with iron. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Many multivitamin products also contain minerals such as calcium, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.

Take your multivitamin with a full glass of water. You may take the multivitamin with food if it upsets your stomach.

The chewable tablet must be chewed or allowed to dissolve in the mouth before swallowing.

Measure the liquid form of this multivitamin using a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Liquid multivitamin may sometimes be mixed with water, fruit juice, or infant formula (but not milk or other dairy products). Follow the directions on the medicine label.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

It is important to take multivitamin with iron regularly to get the most benefit.

Store this medication at room temperature away from moisture and heat. Keep the liquid medicine from freezing.

Store multivitamin in their original container. Storing multivitamin in a glass container can ruin the medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects. Iron and other minerals contained in a multivitamin can also cause serious overdose symptoms.

Overdose symptoms may include severe stomach pain, vomiting, bloody diarrhea, coughing up blood, constipation, loss of appetite, hair loss, peeling skin, warmth or tingly feeling, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine or stools, black and tarry stools, pale skin, easy bruising or bleeding, weakness, shallow breathing, weak and rapid pulse, pale skin, blue lips, and seizure (convulsions).

What should I avoid while taking Nu-Iron Plus (multivitamin with iron)?

Avoid taking any other multivitamin product within 2 hours before or after you take multivitamin with iron. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Avoid the regular use of salt substitutes in your diet if your multivitamin contains potassium. If you are on a low-salt diet, ask your doctor before taking a vitamin or mineral supplement.

Avoid taking an antibiotic medicine within 2 hours before or after you take multivitamin with iron. This is especially important if you are taking an antibiotic such as ciprofloxacin (Cipro), demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), norfloxacin (Noroxin), ofloxacin (Floxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

Certain foods can also make it harder for your body to absorb iron. Avoid taking this multivitamin within 1 hour before or 2 hours after eating fish, meat, liver, and whole grain or “fortified” breads or cereals.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin.

Nu-Iron Plus (multivitamin with iron) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor if you have serious side effects such as:

  • bright red blood in your stools; or

  • pain in your chest or throat when swallowing a ferrous fumarate tablet.

When taken as directed, multivitamin are not expected to cause serious side effects. Less serious side effects may include:

  • constipation, diarrhea;

  • nausea, vomiting, heartburn;

  • stomach pain, upset stomach;

  • black or dark-colored stools or urine;

  • temporary staining of the teeth;

  • headache; or

  • unusual or unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nu-Iron Plus (multivitamin with iron)?

Vitamin and mineral supplements can interact with certain medications, or affect how medications work in your body. Before taking multivitamin with iron, tell your doctor if you also use:

  • acetohydroxamic acid (Lithostat);

  • cimetidine (Tagamet);

  • deferoxamine (Desferal);

  • etidronate (Didronel);

  • diuretics (water pills);

  • heart or blood pressure medications;

  • tretinoin (Vesanoid);

  • isotretinoin (Accutane, Amnesteen, Clavaris, Sotret);

  • dimercaprol (an injection used to treat poisoning by arsenic, lead, or mercury);

  • penicillamine (Cuprimine);

  • pancrelipase (Cotazym, Creon, Ilozyme, Pancrease, Ultrase);

  • trimethoprim and sulfamethoxazole (Cotrim, Bactrim, Septra, TMP/SMX); or

  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others.

This list is not complete and there may be other medications that can interact with or be affected by multivitamin with iron. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about multivitamin with iron.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.01. Revision Date: 03/27/2009 5:13:40 PM.

 

Nu-Med

30/06/10

Generic Name: diphenhydramine (DYE fen HYE dra meen)
Brand Names: Aler-Tab, Allergy, Allermax, Altaryl, Benadryl Allergy, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Children’s Allergy, Diphen Cough, Diphenhist, Dytuss, PediaCare Children’s Allergy, Q-Dryl, Q-Dryl A/F, Siladryl, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep-ettes, Sleep-ettes D, Sominex Maximum Strength Caplet, Theraflu Thin Strips Multi Symptom, Triaminic Thin Strips Cough & Runny Nose, Unisom Sleepgels Maximum Strength, Valu-Dryl

What is Nu-Med (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson’s disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about Nu-Med (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Nu-Med (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

  • glaucoma or increased pressure in the eye;

  • a stomach ulcer;

  • an enlarged prostate, bladder problems or difficulty urinating;

  • an overactive thyroid (hyperthyroidism);

  • hypertension or any type of heart problems; or

  • asthma.

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.


How should I take Nu-Med (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.


What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Nu-Med (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Nu-Med (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

  • sleepiness, fatigue, or dizziness;

  • headache;

  • dry mouth; or

  • difficulty urinating or an enlarged prostate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nu-Med (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

  • anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

  • medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

  • any other medications that make you feel drowsy, sleepy, or relaxed.

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist can provide more information about diphenhydramine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 5.01. Revision Date: 04/02/2009 3:16:39 PM.