Generic Name: calcium carbonate (KAL see um KAR boe nate)
Brand Names: Alka-Mints, Cal-Gest, Calcarb, Calci Mix, Calci-Chew, Calcium Concentrate, Calcium Liquid Softgel, Calcium Oyster Shell, Caltrate, Chooz, Extra Strength Mylanta Calci Tabs, Icar Prenatal Chewable Calcium, Maalox Antacid Barrier, Maalox Childrens’, Maalox Quick Dissolve, Maalox Quick Dissolve Maximum Strength, Maalox Regular Strength, Mylanta Child, Nephro Calci, Os-Cal 500, Oysco 500, Oyst Cal 500, Oyster Cal, Oyster Calcium, Oyster Shell, Pepto Children’s, Rolaids Sodium Free, Rolaids Soft Chew, Titralac, Tums, Tums 500, Tums E-X, Tums Kids, Tums QuikPak, Tums Ultra

What is Oysco 500 (calcium carbonate)?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body.

Calcium carbonate is used to prevent and to treat calcium deficiencies.

Calcium carbonate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Oysco 500 (calcium carbonate)?

Do not take calcium carbonate or antacids that contain calcium without first asking your doctor if you also take other medicines. Calcium can make it harder for your body to absorb certain medicines. Calcium carbonate works best if you take it with food.

What should I discuss with my healthcare provider before taking Oysco 500 (calcium carbonate)?

Before taking this medication, tell your doctor if you have:

• a history of kidney stones; or

• a parathyroid gland disorder.

If you have any of these conditions, you may not be able to take calcium carbonate, or you may need a dose adjustment or special tests during treatment.

Talk to your doctor before taking calcium carbonate if you are pregnant. Talk to your doctor before taking calcium carbonate if you are breast-feeding a baby.

How should I take Oysco 500 (calcium carbonate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Calcium carbonate works best if you take it with food. Swallow the calcium carbonate tablet or capsule with a full glass of water.

The chewable tablet should be chewed before you swallow it.

Use the calcium carbonate powder as directed. Allow the powder to dissolve completely, then consume the mixture.

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, decreased appetite, constipation, confusion, delirium, stupor, and coma.

What should I avoid while taking Oysco 500 (calcium carbonate)?

Follow your healthcare provider’s instructions about any restrictions on food, beverages, or activity.

Oysco 500 (calcium carbonate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• nausea or vomiting;

• decreased appetite;

• constipation;

• dry mouth or increased thirst; or

• urinating more than usual.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs can affect Oysco 500 (calcium carbonate)?

Calcium carbonate can make it harder for your body to absorb other medications you take by mouth. Tell your doctor if you are taking:

• digoxin (Lanoxin, Lanoxicaps);

• antacids or other calcium supplements;

• calcitriol (Rocaltrol) or vitamin D supplements; or

• doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and other drugs may interact with calcium carbonate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about calcium carbonate.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 4.01. Revision Date: 02/26/2010 3:57:27 PM.

Generic Name: calcium and vitamin D combination (KAL see um and VYE ta min D)
Brand Names: Calcarb with D, Calcet, Calcio Del Mar, Calcitrate with D, Calcium 600+D, Caltrate 600 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Citracal + D, Citracal 250 mg + D, Citracal Creamy Bites, Citracal Maximum + D, Citracal Petites, Citrus Calcium with Vitamin D, Dical-D, Os-Cal 250 with D, Os-Cal 500 + D, Os-Cal with D, Oysco 500 with D, Oysco D, Oyst-Cal-D, Oyster Shell Calcium with Vitamin D, Oyster-D, Oystercal-D, Posture-D H/P, Risacal-D

What is Oysco 500 with D (calcium and vitamin D combination)?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance.

Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Calcium and vitamin D combination is used to prevent or to treat a calcium deficiency.

Calcium and vitamin D combination may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Oysco 500 with D (calcium and vitamin D combination)?

Before you take calcium and vitamin D combination, tell your doctor if you have kidney disease, past or present kidney stones, heart disease, circulation problems, a parathyroid disorder, or if you are pregnant or breast-feeding.

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Before taking calcium and vitamin D combination, tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I tell my healthcare provider before taking Oysco 500 with D (calcium and vitamin D combination)?

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take calcium and vitamin D combination, tell your doctor if you have:

• kidney disease;
• past or present kidney stones;

• heart disease;

• circulation problems; or

• a parathyroid gland disorder.

Talk to your doctor before taking calcium and vitamin D combination if you are pregnant. Talk to your doctor before taking calcium and vitamin D combination if you are breast-feeding.

How should I take Oysco 500 with D (calcium and vitamin D combination)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take the calcium and vitamin D regular tablet with a full glass of water.

The chewable tablet should be chewed before you swallow it.

Store calcium and vitamin D combination at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include irregular heartbeat, stomach pain, nausea, vomiting, dry mouth, a metallic taste in your mouth, confusion, loss of appetite, constipation, weakness, headache, confusion, or fainting.

What should I avoid while taking Oysco 500 with D (calcium and vitamin D combination)?

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Oysco 500 with D (calcium and vitamin D combination) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• an irregular heartbeat;

• nausea, vomiting, or decreased appetite;

• dry mouth;

• constipation;

• weakness;

• headache;

• a metallic taste;

• muscle or bone pain; or

• drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Oysco 500 with D (calcium and vitamin D combination)?

Before taking calcium and vitamin D combination, tell your doctor if you are taking:

• digoxin (Lanoxin, Lanoxicaps);

• antacids containing calcium, aluminum, or magnesium;

• other calcium supplements;

• calcitriol (Rocaltrol) or other vitamin D supplements; or

• a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and there may be other drugs that can interact with calcium and vitamin D combination. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about calcium and vitamin D combination.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.04. Revision Date: 11/19/2009 11:12:31 AM.

Generic Name: calcium and vitamin D combination (KAL see um and VYE ta min D)
Brand Names: Calcarb with D, Calcet, Calcio Del Mar, Calcitrate with D, Calcium 600+D, Caltrate 600 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Citracal + D, Citracal 250 mg + D, Citracal Creamy Bites, Citracal Maximum + D, Citracal Petites, Citrus Calcium with Vitamin D, Dical-D, Os-Cal 250 with D, Os-Cal 500 + D, Os-Cal with D, Oysco 500 with D, Oysco D, Oyst-Cal-D, Oyster Shell Calcium with Vitamin D, Oyster-D, Oystercal-D, Posture-D H/P, Risacal-D

What is Oysco D (calcium and vitamin D combination)?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance.

Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Calcium and vitamin D combination is used to prevent or to treat a calcium deficiency.

Calcium and vitamin D combination may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Oysco D (calcium and vitamin D combination)?

Before you take calcium and vitamin D combination, tell your doctor if you have kidney disease, past or present kidney stones, heart disease, circulation problems, a parathyroid disorder, or if you are pregnant or breast-feeding.

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Before taking calcium and vitamin D combination, tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I tell my healthcare provider before taking Oysco D (calcium and vitamin D combination)?

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take calcium and vitamin D combination, tell your doctor if you have:

• kidney disease;
• past or present kidney stones;

• heart disease;

• circulation problems; or

• a parathyroid gland disorder.

Talk to your doctor before taking calcium and vitamin D combination if you are pregnant. Talk to your doctor before taking calcium and vitamin D combination if you are breast-feeding.

How should I take Oysco D (calcium and vitamin D combination)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take the calcium and vitamin D regular tablet with a full glass of water.

The chewable tablet should be chewed before you swallow it.

Store calcium and vitamin D combination at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include irregular heartbeat, stomach pain, nausea, vomiting, dry mouth, a metallic taste in your mouth, confusion, loss of appetite, constipation, weakness, headache, confusion, or fainting.

What should I avoid while taking Oysco D (calcium and vitamin D combination)?

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Oysco D (calcium and vitamin D combination) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• an irregular heartbeat;

• nausea, vomiting, or decreased appetite;

• dry mouth;

• constipation;

• weakness;

• headache;

• a metallic taste;

• muscle or bone pain; or

• drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Oysco D (calcium and vitamin D combination)?

Before taking calcium and vitamin D combination, tell your doctor if you are taking:

• digoxin (Lanoxin, Lanoxicaps);

• antacids containing calcium, aluminum, or magnesium;

• other calcium supplements;

• calcitriol (Rocaltrol) or other vitamin D supplements; or

• a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and there may be other drugs that can interact with calcium and vitamin D combination. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about calcium and vitamin D combination.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.04. Revision Date: 11/19/2009 11:12:31 AM.

Generic Name: calcium and vitamin D combination (KAL see um and VYE ta min D)
Brand Names: Calcarb with D, Calcet, Calcio Del Mar, Calcitrate with D, Calcium 600+D, Caltrate 600 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Citracal + D, Citracal 250 mg + D, Citracal Creamy Bites, Citracal Maximum + D, Citracal Petites, Citrus Calcium with Vitamin D, Dical-D, Os-Cal 250 with D, Os-Cal 500 + D, Os-Cal with D, Oysco 500 with D, Oysco D, Oyst-Cal-D, Oyster Shell Calcium with Vitamin D, Oyster-D, Oystercal-D, Posture-D H/P, Risacal-D

What is Oysco D with Calcium (calcium and vitamin D combination)?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance.

Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Calcium and vitamin D combination is used to prevent or to treat a calcium deficiency.

Calcium and vitamin D combination may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Oysco D with Calcium (calcium and vitamin D combination)?

Before you take calcium and vitamin D combination, tell your doctor if you have kidney disease, past or present kidney stones, heart disease, circulation problems, a parathyroid disorder, or if you are pregnant or breast-feeding.

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Before taking calcium and vitamin D combination, tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

What should I tell my healthcare provider before taking Oysco D with Calcium (calcium and vitamin D combination)?

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take calcium and vitamin D combination, tell your doctor if you have:

• kidney disease;
• past or present kidney stones;

• heart disease;

• circulation problems; or

• a parathyroid gland disorder.

Talk to your doctor before taking calcium and vitamin D combination if you are pregnant. Talk to your doctor before taking calcium and vitamin D combination if you are breast-feeding.

How should I take Oysco D with Calcium (calcium and vitamin D combination)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take the calcium and vitamin D regular tablet with a full glass of water.

The chewable tablet should be chewed before you swallow it.

Store calcium and vitamin D combination at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include irregular heartbeat, stomach pain, nausea, vomiting, dry mouth, a metallic taste in your mouth, confusion, loss of appetite, constipation, weakness, headache, confusion, or fainting.

What should I avoid while taking Oysco D with Calcium (calcium and vitamin D combination)?

Avoid taking any other vitamin or mineral supplements that contain calcium or vitamin D without first talking to your doctor.

Oysco D with Calcium (calcium and vitamin D combination) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• an irregular heartbeat;

• nausea, vomiting, or decreased appetite;

• dry mouth;

• constipation;

• weakness;

• headache;

• a metallic taste;

• muscle or bone pain; or

• drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Oysco D with Calcium (calcium and vitamin D combination)?

Before taking calcium and vitamin D combination, tell your doctor if you are taking:

• digoxin (Lanoxin, Lanoxicaps);

• antacids containing calcium, aluminum, or magnesium;

• other calcium supplements;

• calcitriol (Rocaltrol) or other vitamin D supplements; or

• a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and there may be other drugs that can interact with calcium and vitamin D combination. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your pharmacist can provide more information about calcium and vitamin D combination.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 2.04. Revision Date: 11/19/2009 11:12:31 AM.

Generic Name: oxybutynin (Transdermal route)

ox-i-BUE-ti-nin

Commonly used brand name(s):

In the U.S.

• Gelnique
• Oxytrol

Available Dosage Forms:

• Patch, Extended Release
• Gel/Jelly

Therapeutic Class: Urinary Antispasmodic

Pharmacologic Class: Antimuscarinic

Uses For Oxytrol

Oxybutynin is used to treat symptoms of an overactive bladder, such as incontinence (loss of bladder control) or a frequent need to urinate.

This medicine is available only with your doctor’s prescription.

Before Using Oxytrol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of oxybutynin in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxybutynin in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Potassium Chloride

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Donepezil
• Galantamine
• Ketoconazole
• Rivastigmine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Intestinal or stomach problems (e.g., constipation, ulcerative colitis, or gastroesophageal reflux disease [GERD]) or
• Myasthenia gravis (severe muscle weakness) or
• Urinary problems (e.g., blockage)—Use with caution. May make these conditions worse.

• Narrow-angle glaucoma, uncontrolled or
• Stomach problems (e.g., gastric retention) or
• Urinary retention (hard to pass urine)—Should not be used in patients with these conditions.

Proper Use of oxybutynin

This section provides information on the proper use of a number of products that contain oxybutynin. It may not be specific to Oxytrol. Please read with care.

It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Talk to your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away.

To use the gel:

• Wash your hands with soap and water before and after using this medicine.
• Before applying this medicine, wash the application site (e.g., stomach, upper arms, shoulders, or thighs) with mild soap and water. Rinse well and pat dry.
• Tear and squeeze the entire contents of the packet into the palm of your hand or directly on the application site. Gently rub it until the gel dries.
• Do not apply this medicine on the same application site you applied the last one.
• Do not bathe, swim, shower, or exercise for 1 hour after applying oxybutynin.
• Cover the application site with a dry cloth after the medicine has dried to avoid direct contact or transfer of oxybutynin to another person.

To use the skin patch:

• Use this medicine exactly as directed by your doctor. It will work only if applied correctly.
• Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands.
• Apply the patch right away after removing it from the protective pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch.
• Apply the patch to a clean, dry, and intact skin area on your stomach, hips, or buttocks. Choose an area with little or no hair and free of scars, cuts, or irritation. Avoid putting the patch on areas where it could be rubbed off by tight clothing.
• Press the patch firmly in place with your fingertips to make sure that the edges of the patch stick well.
• When putting on each new patch, choose a different place within these areas. Do not put the new patch on the same place you wore the last one. Be sure to remove the old patch before applying a new one.

The gel form contains alcohol which is flammable. Do not use this medicine near heat, an open flame, or while smoking.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For bladder problems:
  • For transdermal dosage form (gel):
    • Adults—Apply the gel on dry, intact skin once a day.
    • Children—Use and dose must be determined by your doctor.
  • For transdermal dosage form (skin patch):
    • Adults—Apply one patch two times per week, which is one patch every 3 to 4 days.
    • Children—Use and dose must be determined by your doctor.

Missed Dose

If you forget to wear or change a patch, put one on as soon as you can. If it is almost time to put on your next patch, wait until then to apply a new patch and skip the one you missed. Do not apply extra patches to make up for a missed dose.

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Precautions While Using Oxytrol

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are using this medicine, since overheating may result in heat stroke.

This medicine may cause some people to become dizzy, drowsy, or have blurred vision. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy, not alert, or not able to see well.

This medicine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Avoid drinking alcohol while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Oxytrol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bladder pain
• blistering, crusting, irritation, itching, or reddening of the skin
• bloody or cloudy urine
• burning, skin rash, swelling, or soreness at the application site
• cracked, dry, or scaly skin
• difficult, burning, or painful urination
• frequent urge to urinate
• lower back or side pain
• unusually warm skin

Less common

• Abdominal or stomach pain
• diarrhea
• loss of appetite
• nausea
• weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Chest pain or discomfort
• confusion
• decrease in frequency of urination
• decrease in urine volume
• decreased urination
• difficulty in passing urine (dribbling)
• dizziness
• dry mouth
• fainting
• fast, slow, or irregular heartbeat
• feeling of warmth
• fever
• increase in heart rate
• lightheadedness
• pounding or rapid pulse
• rapid breathing
• redness of the face, neck, arms, and occasionally, upper chest
• sunken eyes
• thirst
• unusual tiredness or weakness
• vomiting
• wrinkled skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Body aches or pain
• chills
• cough
• difficulty with breathing
• ear congestion
• headache
• loss of voice
• nasal congestion
• runny nose
• sneezing
• sore throat

Less common

• Back pain
• bloated
• changes in vision
• constipation
• excess air or gas in the stomach or intestines
• full feeling
• muscle aches
• passing gas
• sleepiness or unusual drowsiness
• stuffy or runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Generic Name: Oxybutynin (OX-i-BYOO-ti-nin)
Brand Name: Oxytrol

Oxytrol System is used for:

Relieving symptoms of bladder problems (urinary urgency, frequency, or leakage; loss of bladder control; and painful urination) in certain patients. It may also be used for other conditions as determined by your doctor.

Oxytrol System is an anticholinergic. It works by relaxing muscles in the bladder.

Do NOT use Oxytrol System if:

• you are allergic to any ingredient in Oxytrol System
• you have bladder blockage or are unable to urinate
• you have certain stomach or bowel problems (eg, blockage, decreased muscle movement) or tightening of the esophagus
• you have uncontrolled narrow-angle glaucoma
• you have heart problems caused by severe bleeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Oxytrol System:

Some medical conditions may interact with Oxytrol System. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have trouble urinating or have very poor health
• if you have a history of heart problems (eg, heart failure, fast or irregular heartbeat), high blood pressure, nervous system problems, esophagus problems (eg, reflux disease, inflammation), stomach or bowel problems (eg, colitis, inflammation), or hiatal hernia
• if you have a history of liver or kidney problems, myasthenia gravis, an enlarged prostate, an overactive thyroid, or glaucoma, or if you are at risk for glaucoma

Some MEDICINES MAY INTERACT with Oxytrol System. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticholinergics (eg, scopolamine), azole antifungals (eg, ketoconazole), or macrolide antibiotics (eg, erythromycin) because they may increase the risk of Oxytrol System’s side effects
• Bisphosphonates (eg, alendronate) because the risk of irritation of the esophagus may be increased
• Phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by Oxytrol System and they may increase the risk of Oxytrol System’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxytrol System may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Oxytrol System:

Use Oxytrol System as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Oxytrol System. Talk to your pharmacist if you have questions about this information.
• Apply the patch to a clean, dry, smooth area of your skin on your stomach, hips, or buttocks. Apply it to an area under clothing to protect it from sunlight. Avoid applying it to your waistline because clothing may rub against the patch.
• Do NOT apply the patch to oily, damaged, or irritated skin. Avoid using oils, lotions, or powders near the application site because the patch may not stick to your skin.
• To use Oxytrol System, open the pouch and remove the patch. Apply it right away. Carefully remove the first protective liner and place the patch firmly onto your skin. Do not touch the adhesive side of the patch. Bend the patch in half and gently roll the remaining part onto your skin. The second protective liner should come off of the patch. Gently apply firm pressure over the patch to be sure it stays in place.
• When it is time to apply a new patch, remove the old patch carefully. Fold the patch in half with the sticky sides together. Discard the patch out of the reach of children and pets because it may still contain medicine.
• Use a different skin site each time you apply a new patch. Do not reuse the same site within 7 days.
• Use Oxytrol System on a regular schedule to get the most benefit from it. Using Oxytrol System at the same time each day will help you remember to use it.
• Continue to use Oxytrol System event if you feel well. Do not miss any doses.
• If the patch comes off, press it back in place and continue to follow your regular application schedule. If it does not stay on, throw it away and put a new patch on in a different area. Continue to follow your regular application schedule.
• If you forget to change the patch on the correct day, remove the old patch and apply a new patch to a different application site as soon as you remember. Continue to follow your regular application schedule. Do not use 2 patches at once.

Ask your health care provider any questions you may have about how to use Oxytrol System.

Important safety information:

• Oxytrol System may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Oxytrol System with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Oxytrol System; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Oxytrol System may cause decreased sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur. Contact your doctor if you have been exposed to high temperatures and you develop fever; flushing; hot, dry skin; severe or persistent headache; dizziness; sudden fatigue; fast heartbeat; seizures; or fainting.
• Oxytrol System may cause dry mouth. To hep relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Ask your doctor or pharmacist if you have any questions.
• Using Oxytrol System while bathing, swimming, showering, or exercising will not change the way it works. However, avoid rubbing the patch area during these activities.
• Always remove the patch carefully and slowly to avoid damage to your skin. If there is adhesive left on your skin, gently wash the area with warm, soapy water. You may also use baby oil or a medical adhesive removal pad if need. Do not use alcohol or nail polish remover because these may irritate the skin.
• After removing the patch, there may be minor redness of your skin. It should disappear after several hours. Tell your doctor if the irritation or redness becomes worse or if it does not go away.
• Use Oxytrol System with caution in the ELDERLY; they may be more sensitive to its effects.
• Oxytrol System should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: It is not known if Oxytrol System can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oxytrol System while you are pregnant. It is not known if Oxytrol System is found in breast milk. If you are or will be breast-feeding while you use Oxytrol System, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Oxytrol System:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; diarrhea; dizziness; drowsiness; dry eyes, nose, skin, or mouth; headache; indigestion; nausea; minor redness, itching, or irritation at patch application site; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficult or painful urination; fast or irregular heartbeat; fever; hallucinations; pain, burning, blistering, or oozing at the application site; seizures; swelling of the hands, ankles, or feet; vision problems.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include coma; delirium; fever; flushing; hallucinations; irregular heartbeat; paralysis; seizures; severe or persistent dizziness or headache; tremor; trouble breathing; vomiting.

Proper storage of Oxytrol System:

Store Oxytrol System at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in original packaging until just before use. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Oxytrol System out of the reach of children and away from pets

General information:

• If you have any questions about Oxytrol System, please talk with your doctor, pharmacist, or other health care provider.
• Oxytrol System is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Oxytrol System. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Generic Name: oxytocin (ox e TOW sin)
Brand Names: Pitocin, Syntocinon

What is oxytocin?

Oxytocin is a natural hormone that causes the uterus to contract.

Oxytocin is used to induce labor, strengthen labor contractions during childbirth, control bleeding after childbirth, or to induce an abortion.

Oxytocin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about oxytocin?

Oxytocin should be administered as an injection into a muscle or intravenously by a healthcare provider. It should be administered in a clinical setting where a healthcare provider can monitor uterine contractions and other vital signs (blood pressure, heart rates) and where an emergency situation can be handled properly.

What should I discuss with my healthcare provider before using oxytocin?

Do not take oxytocin without first talking to your doctor if you

• have or have had cervical cancer;

• have an allergy to oxytocin, other medications, dyes, foods, or preservatives;

• have eclampsia;

• have herpes;

• have had more than 7 pregnancies;

• are experiencing premature labor;

• have had a caesarean section (C-section);

• have had any surgery on the cervix or uterus;

• have a prolapsed uterus; or

• have a breech, placenta previa or any other issues with the fetus or umbilical cord.

You may not be able to use oxytocin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Tell your doctor about all prescription or over-the-counter medicines including vitamins, minerals, and herbal products that your are taking.

Tell your doctor if you drink alcohol or caffeine drinks regularly, if you are a smoker or if you use illegal drugs. These factors can affect the way oxytocin works in your body.

There are no known indications for the use of oxytocin in the first or second trimester of pregnancy other than in relation to spontaneous or induced abortion. Based on the wide experience with this drug and its properties, it would not be expected to present a risk of harm to the baby when used as indicated under the supervision of a trained healthcare professional. Ask your doctor to answer any questions you have about the use of oxytocin and your pregnancy. Do not use oxytocin without first talking to your doctor if you are breast-feeding a baby.

How should I use oxytocin?

Oxytocin should be administered as an injection into a muscle or intravenously by a healthcare provider. It should be administered in a clinical setting where a healthcare provider can monitor uterine contractions and other vital signs (blood pressure, heart rates) and where an emergency situation can be handled properly.

Your healthcare provider will store oxytocin as directed by the manufacturer.

What happens if I miss a dose?

Since the medication will be administered by a healthcare provider, missing a dose should not occur.

What happens if I overdose?

If an overdose of oxytocin is suspected, seek emergency medical attention or contact your healthcare provider immediately.

Oxytocin should be administered in a clinical setting where a healthcare provider can monitor uterine contractions and other vital signs (blood pressure, heart rates) and where an emergency situation can be handled immediately.

What should I avoid while using oxytocin?

Tell your doctor if you drink alcohol or caffeine drinks regularly, if you are a smoker or if you use illegal drugs. These factors can affect the way oxytocin works in your body.

Oxytocin side effects

Side effects with oxytocin are not common. Serious side effects include:

• an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or fainting);

• difficulty urinating;

• chest pain or irregular heart beat;

• difficulty breathing;

• confusion;

• sudden weight gain or excessive swelling;

• severe headache;

• rash;

• excessive vaginal bleeding; or

• seizures.

Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience

• redness or irritation at the injection site;

• loss of appetite; or

• nausea or vomiting.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Oxytocin Dosing Information

Usual Adult Dose for Labor Induction:

Initial dose: 0.5 to 1 milliunits IV infusion per hour. At 30 to 60 minute intervals the dose should be gradually increased in increments of 1 to 2 milliunits until the desired contraction pattern has been established.

Usual Adult Dose for Postpartum Bleeding:

10 to 40 units IV infusion in 1000 mL at a rate sufficient to control bleeding.
10 units IM after delivery of placenta.

Usual Adult Dose for Abortion:

After suction or sharp curettage for an incomplete, inevitable or elective abortion:

10 units in 500 mL IV infusion. Adjust rate to assist uterus in contraction.

After intra-amniotic injection for midtrimester elective abortion:

10 to 20 milliunits per minute IV infusion. The total dose should not exceed 30 units in a 12 hour period due to the risk of water intoxication.

What other drugs will affect oxytocin?

Other drugs can interact with oxytocin resulting in dangerous side effects and/or decreased effectiveness. Do not take any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, without first talking to your doctor during treatment with oxytocin.

Where can I get more information?

• Your pharmacist has additional information about oxytocin written for health professionals that you may read.

• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2006 Cerner Multum, Inc. Version: 1.02. Revision Date: 4/12/2009 4:37:45 PM.

ox-i-TOE-sin

Commonly used brand name(s):

In the U.S.

• Pitocin

Available Dosage Forms:

• Solution

Therapeutic Class: Uterine Stimulant

Pharmacologic Class: Pituitary Hormone, Posterior

Uses For oxytocin

Oxytocin is a hormone used to help start or continue labor and to control bleeding after delivery. It is also sometimes used to help milk secretion in breast-feeding.

Oxytocin may also be used for other conditions as determined by your doctor.

In general, oxytocin should not be used to start labor unless there are specific medical reasons. Be sure you have discussed this with your doctor before receiving oxytocin.

oxytocin is available only with your doctor’s prescription.

Novartis Pharmaceuticals removed Syntocinon® nasal spray from the market in March 1995.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, oxytocin is used in certain patients for the following:

• Testing the ability of the placenta to support a pregnancy.

Before Using oxytocin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For oxytocin, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to oxytocin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

No information is available on the relationship of age to the effects of oxytocin in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of oxytocin in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of oxytocin. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems (e.g., subarachnoid hemorrhage) or
• Hypertension (high blood pressure)—May make these conditions worse.

• Cephalopelvic disproportion or
• Cervical cancer or
• Fetal distress or
• Grand multiparity (giving birth more than five times) or
• Major surgery on the cervix or uterus (e.g., caesarean delivery), history of or
• Overdistended uterus or
• Premature fetus or
• Problems with uterine contraction (e.g., uterine atony, strong uterine contractions) or
• Toxemia, severe or
• Unfavorable fetal position (e.g., transverse lies) or
• Other conditions that may require caesarean delivery (e.g., cord prolapse, total placenta previa, vasa previa, or during an emergency)—Should not be used in patients with these conditions.

• Kidney disease—Use with caution. Effects may be increased because of slower removal of oxytocin from the body.

Proper Use of oxytocin

A nurse or other trained health professional will give you oxytocin. oxytocin is given through a needle placed in one of your veins or as a shot into one of your muscles.

Precautions While Using oxytocin

Oxytocin can be very useful for helping labor. However, there are certain risks with using it. Oxytocin causes contractions of the uterus. In women who are unusually sensitive to its effects, these contractions may become too strong. In rare cases, this may lead to tearing of the uterus. Also, if contractions are too strong, the supply of blood and oxygen to the fetus may be decreased.

Oxytocin may cause jaundice and eye problems such as retinal hemorrhage in some newborn infants. If you have concerns about this, ask your doctor.

oxytocin may cause a serious condition called water intoxication. Tell your doctor right away if you start having have confusion, drowsiness, headache, or seizures while you are receiving oxytocin.

oxytocin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

• Confusion
• convulsions (seizures)
• difficulty in breathing
• dizziness
• fast or irregular heartbeat
• headache (continuing or severe)
• hives
• pelvic or abdominal pain (severe)
• skin rash or itching
• vaginal bleeding (increased or continuing)
• weakness
• weight gain (rapid)

Incidence not known

• Abdominal pain or cramping
• blood clotting problem that causes prolonged bleeding
• chest pain or discomfort
• cough
• difficulty swallowing
• extra heartbeats
• fainting
• lightheadedness
• pounding or rapid pulse
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• severe bleeding after giving birth
• shortness of breath
• tightness in the chest
• unusual tiredness or weakness
• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Restlessness
• shakiness
• sleepiness
• slow to respond
• slurred speech
• unconsciousness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

• Nausea
• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Generic Name: Oxyquinolone (ox-ee-QUIN-o-lone)
Brand Name: Trimo-San

Oxyquinolone is used for:

Restoring and maintaining healthy vaginal acidity and reducing odor-causing bacteria. It also acts as a lubricant. It may also be used for other conditions as determined by your doctor.

Oxyquinolone is a deodorant gel.It works by promoting healthy acidity in the vagina, which keeps odor-causing bacteria from flourishing.

Do NOT use Oxyquinolone if:

• you are allergic to any ingredient in Oxyquinolone

Contact your doctor or health care provider right away if any of these apply to you.

Before using Oxyquinolone:

Some medical conditions may interact with Oxyquinolone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Oxyquinolone. However, no specific interactions with Oxyquinolone are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxyquinolone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Oxyquinolone:

Use Oxyquinolone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Unscrew the cap from the tube. Pierce the end of the tube with the top of the cap. Attach threaded end of the applicator to the tube. Squeeze the tube from the bottom until the correct amount of medicine has been dispensed into the applicator. Unscrew the applicator from the tube.
• Gently insert the applicator about ½ inch into the vagina. Firmly squeeze the bulb once to dispense the gel into the vagina, keeping the bulb squeezed until the applicator is removed from the vagina.
• Check with your doctor or pharmacist regarding use of this product if you have a pessary.
• Clean the applicator immediately after use by pumping the bulb several times while holding the applicator under water.
• Wipe the open end of the tube where it attaches to the applicator and the inside of the cap after each use. Recap the medicine tightly.
• If you miss a dose of Oxyquinolone, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Oxyquinolone.

Important safety information:

• Oxyquinolone is for vaginal use only. Do not get Oxyquinolone in your eyes, nose, or mouth.
• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Oxyquinolone, discuss with your doctor the benefits and risks of using Oxyquinolone during pregnancy. It is unknown if Oxyquinolone is excreted in breast milk. If you are or will be breast-feeding while you are using Oxyquinolone, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Oxyquinolone:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; stomach pain or cramps; unusually strong odor; unusual swelling or tenderness; vaginal discharge, burning, or itching.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Oxyquinolone may be harmful if swallowed.

Proper storage of Oxyquinolone:

Store Oxyquinolone at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep Oxyquinolone out of the reach of children and away from pets.

General information:

• If you have any questions about Oxyquinolone, please talk with your doctor, pharmacist, or other health care provider.
• Oxyquinolone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Oxyquinolone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.