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ropivacaine

30/06/10

Generic Name: ropivacaine (roe PIV a kane)
Brand names: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus

What is ropivacaine?

Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains.

Ropivacaine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about ropivacaine?

You should not receive ropivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving ropivacaine, tell your doctor if you are allergic to any drugs, or if you have liver disease, heart disease, or kidney disease.

Tell your caregivers at once if you have a serious side effect such as: confusion, feeling like you might pass out, problems with speech or vision, ringing in your ears, numbness or tingling around your mouth, seizure, weak or shallow breathing, fast or slow heart rate, weak pulse, gasping, or feeling unusually hot.

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from ropivacaine.

What should I discuss with my health care provider before receiving ropivacaine?

You should not receive ropivacaine if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving ropivacaine, tell your doctor if you are allergic to any drugs, or if you have:

liver disease;
heart disease; or
kidney disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely receive ropivacaine.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. It is not known whether ropivacaine can pass into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is ropivacaine given?

Ropivacaine is given as an injection through a needle placed into an area of your middle or lower back near your spine. You will receive this injection in a clinic or hospital setting.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving ropivacaine.

What happens if I miss a dose?

Since ropivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include extreme drowsiness, ringing in your ears, blurred vision, fainting, seizure (convulsions), weak or shallow breathing, or breathing that stops.

What should I avoid after receiving ropivacaine?

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

Ropivacaine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives or red skin rash; dizziness; sneezing; difficulty breathing; nausea or vomiting; sweating; swelling of your face, lips, tongue, or throat. Tell your caregivers at once if you have any of these serious side effects:

feeling anxious, restless, confused, or like you might pass out;
problems with speech or vision;
ringing in the ears, metallic taste, vision problems, numbness or tingling around your mouth, or tremors;
seizure (convulsions);
weak or shallow breathing;
slow heart rate, weak pulse; or
fast heart rate, gasping, feeling unusually hot.

Less serious side effects include:

nausea, vomiting;
headache, back pain;
fever;
itching;
numbness or tingly feeling; or
problems with urination or sexual function.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Ropivacaine Dosing Information

Usual Adult Dose for Local Anesthesia:

Postoperative analgesia:
Lumbar epidural method:
Initial: 75 to 200 mg injected via lumbar epidural administration. The onset of action should occur within 10 to 30 minutes and should last approximately 2 to 6 hours.
Maintenance:
12 to 28 mg/hour administered via lumbar epidural continuous infusion.

Thoracic epidural:
Initial:
25 to 75 mg injected via thoracic epidural administration.
Maintenance:
12 to 28 mg/hour administered via thoracic epidural continuous infusion.
Cumulative epidural dosages up to 770 mg over a 24 hour period for postoperative pain have been well tolerated in adult patients.

Nerve block:
A major nerve block such as a brachial plexus block, may be established by injecting 175 to 250 mg of ropivacaine into the appropriate area of the nerve. The onset of action occurs in approximately 15 to 30 minutes with a duration of 5 to 8 hours.

A field block such as a minor nerve block or infiltration, may be established by injecting 5 to 200 mg of ropivacaine. The onset of action occurs within 1 to 15 minutes with an expected duration of 2 to 6 hours.

Usual Adult Dose for Cesarean Section:

Lumbar epidural method:
100 to 150 mg injected via lumbar epidural administration. The onset of action should occur within 15 to 25 minutes and should last approximately 2 to 4 hours. It is recommended that the 0.5% solution in doses not exceeding 150 mg be employed for cesarean sections.

Usual Adult Dose for Labor Pain:

Lumbar epidural method:
Initial: 20 to 40 mg injected via lumbar epidural administration. The onset of action should occur within 10 to 15 minutes and should last approximately 0.5 to 1.5 hours.
Maintenance:
12 to 28 mg/hour administered via lumbar epidural continuous infusion.

Incremental injections, also known as top- ups, may be made by administering a dose of 20 to 30 mg per hour.

Usual Pediatric Dose for Local Anesthesia:

Caudal Block:
2 to 8 years: 2 mg/kg

Epidural Block (other than caudal block):
1.7 mg/kg

Epidural continuous infusion:
4 months to 7 years: Loading dose of 1 mg/kg followed by 0.4 mg/kg/hr continuous epidural infusion

What other drugs will affect ropivacaine?

Many drugs can interact with ropivacaine. Below is just a partial list. Tell your doctor if you are using:

birth control pills or other hormones;
cimetidine (Tagamet);
cyclobenzaprine (Flexeril);
interferon (Actimmune, Roferon, Intron, Rebetron, and others);
ondansetron (Zofran);
propranolol (Inderal);
theophylline (Elixophyllin, Respbid, Slo-Bid, Theobid, Theo-Dur);
verapamil (Calan, Covera, Isoptin, Verelan);
warfarin (Coumadin);
a heart rhythm medication such as amiodarone (Cordarone, Pacerone), bretylium (Bretylan, Tosylate), dofetilide (Tikosyn), ibutilide (Corvert), mexiletine (Mexitil), or sotalol (Betapace);
antidepressants such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), fluvoxamine (Luvox), imipramine (Janimine, Tofranil); or
medicines to treat psychiatric disorders, such as clozapine (Clozaril, Fazaclo), haloperidol (Haldol), olanzapine (Zyprexa, Zydis).

This list is not complete and there may be other drugs that can interact with ropivacaine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about ropivacaine.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

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ropivacaine (Injection route)

30/06/10

roe-PIV-a-kane

Commonly used brand name(s):

In the U.S.

Naropin

Available Dosage Forms:

Solution

Therapeutic Class: Anesthetic, Local

Chemical Class: Amino Amide

Uses For ropivacaine

Ropivacaine is a local anesthetic given by injection to cause loss of feeling before and during surgery or labor and delivery. It does not cause loss of consciousness.

Ropivacaine is given only by or under the immediate supervision of a medical doctor, or by a specially trained nurse, in the doctor’s office or in a hospital.

Before Using ropivacaine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ropivacaine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ropivacaine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on ropivacaine have been done only in adolescents and adults, and there is no specific information comparing use of ropivacaine in children with use in other age groups.

Geriatric

Many medicines have not been specifically studied in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ropivacaine in the elderly with use in other age groups. Based on information about similar medicines, it is expected that elderly people will be more sensitive than younger adults to the effects of ropivacaine. This may increase the chance of side effects.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using ropivacaine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Hyaluronidase
St John’s Wort

Using ropivacaine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Ciprofloxacin
Fluvoxamine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of ropivacaine

Dosing

The dose of ropivacaine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of ropivacaine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Your age;
Your general physical condition;
The reason the medicine is being given; and
Other medicines you are taking or will receive before or after ropivacaine is given.

Precautions While Using ropivacaine

For patients going home before the numbness or loss of feeling caused by ropivacaine wears off:

During the time that the injected area feels numb, serious injury can occur without your knowing it. Be especially careful to avoid injury until the medicine wears off or feeling returns to the area.

ropivacaine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare

Burning or prickling sensation
fever
itching

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Back pain
difficulty urinating
headache
pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Advanced,R

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Rondex-DM

30/06/10

Generic Name: chlorpheniramine, dextromethorphan, and phenylephrine (klor feh NEER a meen, dex troe meh THOR fan, and feh nill EH frin)
Brand Names: Alka-Seltzer Plus Cold and Cough, C-Phen DM, C-Phen DM Drops, Cardec DM, Cardec DM Drops, Ceron-DM, Ceron-DM Drops, Cerose DM, Corfen-DM, CP Dec DM, CP Dec-DM Drops, De-Chlor DM, De-Chlor DR, Dec-Chlorphen DM, Dex PC, DM-PE-Chlor, Donatussin DM Drops, Ed A-Hist DM, HistadecDM, Maxiphen ADT, Mintuss DR, nasohist-DM, Neo DM Drops, Nohist-DMX, Norel DM, P Chlor DM, PD-Cof, PD-Cof Drops, Poly-Tussin DM, Quartuss DM, Reme Tussin DM, Rondec-DM, Rondec-DM Drops, Rondex-DM, Rondex-DM Drops, Sildec-PE DM, Sildec-PE DM Drops, Tri-Vent DPC, Trital DM, Tussplex DM, Zotex-12D

What is Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, dextromethorphan, and phenylephrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Chlorpheniramine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

kidney disease;
liver disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
a stomach ulcer or a stomach obstruction,
emphysema or chronic bronchitis; or
an enlarged prostate or urination problems.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. If you use the effervescent tablet, drop the tablet in 8 ounces of water and allow it to dissolve completely. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
confusion, hallucinations;
slow, shallow breathing;
urinating less than usual or not at all;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

blurred vision;
dry mouth;
nausea, stomach pain, constipation;
mild loss of appetite, stomach upset;
warmth, tingling, or redness under your skin;
feeling excited or restless;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness;
problems with memory or concentration; or
ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant;
a diuretic (water pill);
medication to treat irritable bowel syndrome;
celecoxib (Celebrex);
cinacalcet (Sensipar);
imatinib (Gleevec);
quinidine (Quinaglute, Quinidex);
ranolazine (Ranexa)
ritonavir (Norvir);
sibutramine (Meridia);
terbinafine (Lamisil);
medicines to treat high blood pressure;
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

This list is not complete and there may be other drugs that can interact with chlorpheniramine, dextromethorphan, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

Comments (0)

Rondex-DM Drops

30/06/10

What is Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

What should I discuss with my healthcare provider before taking Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

kidney disease;
liver disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
a stomach ulcer or a stomach obstruction,
emphysema or chronic bronchitis; or
an enlarged prostate or urination problems.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

How should I take Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
confusion, hallucinations;
slow, shallow breathing;
urinating less than usual or not at all;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

blurred vision;
dry mouth;
nausea, stomach pain, constipation;
mild loss of appetite, stomach upset;
warmth, tingling, or redness under your skin;
feeling excited or restless;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness;
problems with memory or concentration; or
ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant;
a diuretic (water pill);
medication to treat irritable bowel syndrome;
celecoxib (Celebrex);
cinacalcet (Sensipar);
imatinib (Gleevec);
quinidine (Quinaglute, Quinidex);
ranolazine (Ranexa)
ritonavir (Norvir);
sibutramine (Meridia);
terbinafine (Lamisil);
medicines to treat high blood pressure;
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

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Ronoxidil

30/06/10

Generic Name: minoxidil topical (mi NOX i dill)
Brand Names: Rogaine, Rogaine Extra Strength, Ronoxidil

What is Ronoxidil (minoxidil topical)?

The exact way that minoxidil topical works is not known.

Minoxidil topical is used to treat male pattern baldness.

Minoxidil topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Ronoxidil (minoxidil topical)?

Do not use minoxidil topical if the skin on your scalp is damaged, irritated, or sunburned. This may allow more of the medication to be absorbed by your body, which could be dangerous.

Do not use this medication on any part of your body other than your scalp. Application to other body parts can be dangerous.

Do not use other topical products on your scalp during treatment with minoxidil topical, unless otherwise directed by your doctor.

What should I discuss with my healthcare provider before using Ronoxidil (minoxidil topical)?

Do not use minoxidil topical if the skin on your scalp is damaged, irritated, or sunburned. This may allow more of the medication to be absorbed by your body, which could be dangerous.

Before using minoxidil topical tell your doctor if you have heart disease. Minoxidil absorbed by the body can affect the heart.

Minoxidil topical is in the FDA pregnancy category C. This means that it is not known whether minoxidil topical will be harmful to an unborn to baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Minoxidil may affect a nursing baby. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should I use Ronoxidil (minoxidil topical)?

Use minoxidil topical exactly as directed by your doctor or as directed in the package labeling. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Dry your hair and scalp before applying minoxidil topical.

Apply the prescribed amount, usually 1 mL, to the affected areas of the scalp. Minoxidil topical is usually applied twice daily, in the morning and at night.

Wash your hands after applying minoxidil topical.

Avoid getting this medication in the eyes, nose, or mouth. If this occurs, rinse the area with water.

Do not use minoxidil topical if the skin on your scalp is damaged, irritated, or sunburned. This may allow more of the medication to be absorbed by your body, which could be dangerous. Do not use more than 2 mL of minoxidil topical in one day. More medication will not increase or hasten hair growth but it may cause dangerous side effects.

Do not use this medication on any part of your body other than your scalp. Application to other body parts can be dangerous.

It may take 4 months or more before new hair growth is seen. New hair is usually soft, colorless, and barely visible. With further treatment, the hair will become similar in color and thickness to existing hair.

If no hair growth is seen after 4 months of treatment, discontinuation of minoxidil topical should be considered.

If treatment is discontinued, new hair growth will usually be shed within a few months.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and use only the next regularly scheduled dose. Do not use a double dose of this medication.

What happens if I overdose?

An overdose of minoxidil is not likely to occur.

If an unusually large dose is applied, or if the medication is ingested, seek emergency medical attention.

Symptoms of a minoxidil topical overdose are not known but may include very low blood pressure (fainting, dizziness, confusion); an irregular or fast heart rate; headache; and flushing (redness, warmth) of the skin.

What should I avoid while using Ronoxidil (minoxidil topical)?

Do not use this medication on any part of your body other than your scalp. Application to other body parts can be dangerous.

Do not use other topical products on your scalp during treatment with minoxidil topical, unless otherwise directed by your doctor.

Ronoxidil (minoxidil topical) side effects

If you experience any of the following serious side effects, stop using minoxidil topical and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
chest pain;
irregular or very fast heartbeats;
dizziness or lightheadedness; or
fainting.

Continue to use minoxidil topical and talk to your doctor when it is convenient if you experience

itching, redness, dryness, or flaking of the scalp; or
a headache.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Ronoxidil (minoxidil topical)?

Do not use other topical products on your scalp during treatment with minoxidil topical, unless otherwise directed by your doctor.

Drugs other than those listed here may also interact with minoxidil topical or affect your condition. Talk to your doctor and pharmacist before using any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

Your pharmacist has additional information about minoxidil topical written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

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ropinirole (Oral route)

30/06/10

roe-PIN-i-role

Commonly used brand name(s):

In the U.S.

Requip
Requip XL

Available Dosage Forms:

Tablet
Tablet, Extended Release

Therapeutic Class: Antiparkinsonian

Pharmacologic Class: Dopamine Agonist

Uses For ropinirole

Ropinirole is used alone or with other medicines to treat Parkinson’s disease.

It is also used to treat a condition called Restless Legs Syndrome (RLS). RLS is a neurologic disorder that affects sensation and movement in the legs and causes the legs to feel uncomfortable. This results in an overwhelming feeling of wanting to move your legs to make them comfortable.

ropinirole is available only with your doctor’s prescription.

Before Using ropinirole

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ropinirole, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ropinirole or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of ropinirole in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ropinirole in the elderly. However, elderly patients are more likely to have age-related liver problems or to develop hallucinations (seeing, hearing, or feeling things that are not there), which may require caution in patients receiving ropinirole.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using ropinirole with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Warfarin

Using ropinirole with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Ciprofloxacin
Kava

Interactions with Food/Tobacco/Alcohol

Using ropinirole with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use ropinirole, or give you special instructions about the use of food, alcohol, or tobacco.

Proper Use of ropinirole

Take ropinirole every day exactly as ordered by your doctor in order to improve your condition as much as possible. Do not take more of it or less of it, and do not take it more or less often than your doctor ordered.

Read the Patient Information leaflet before you take ropinirole and each time you get your prescription refilled.

ropinirole may be taken with or without food, or on an empty or full stomach. Taking ropinirole with food may reduce nausea.

Swallow the extended-release tablets whole. Do not split, crush, or chew it.

Dosing

The dose of ropinirole will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of ropinirole. If your dose is different, do not change it unless your doctor tells you to do so.

For oral dosage form (extended-release tablets):
- For Parkinson’s disease:
  - Adults—At first, 2 milligrams (mg) once a day for 1 to 2 weeks. Your doctor may increase your dose as needed and tolerated. However, the dose is usually not more than 24 mg per day.
  - Children—Use and dose must be determined by your doctor.

For oral dosage form (tablets):
- For Parkinson’s disease:
  - Adults—At first, 0.25 milligrams (mg) three times a day. Your doctor will increase your dose as needed and tolerated. However, the dose is usually not more than 24 mg a day.
  - Children—Use and dose must be determined by your doctor.
- For Restless Legs Syndrome:
  - Adults—At first, 0.25 mg once a day, 1 to 3 hours before bedtime. Your doctor will increase your dose as needed and tolerated. However, the dose is usually not more than 4 mg a day.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of ropinirole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using ropinirole

It is important that your doctor check your progress at regular visits to allow changes in your dose and to check for any unwanted effects.

Do not stop taking ropinirole without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping completely.

People taking ropinirole have reported falling asleep without warning during activities of daily living, including driving, which sometimes resulted in accidents. This may happen as late as one year after taking the medicine. Therefore, make sure you know how you react to ropinirole before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, or able to think or see well.

ropinirole will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using ropinirole.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. These symptoms are more likely to occur when you begin taking ropinirole, or when the dose is increased. Getting up slowly may help. If you should have this problem, check with your doctor.

Hallucinations may occur in some patients. This is more common with elderly patients. If you have hallucinations, check with your doctor.

Since smoking may decrease the treatment effects of ropinirole, it is best to avoid smoking while you are using it. If you have any questions about this, check with your doctor.

It is important that your doctor check your skin for melanoma regularly if you have Parkinson’s disease. .

Some people who have used ropinirole had unusual changes in their behavior. Talk with your doctor if you start having problems with gambling or increased sex drive while using ropinirole.

ropinirole Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Confusion
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
drowsiness
falling
nausea
seeing, hearing, or feeling things that are not there (hallucinations)
sleepiness or unusual drowsiness
swelling of legs
twisting, twitching, or other unusual body movements
unusual tiredness or weakness
worsening of parkinsonism

Less common

Abdominal pain
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in urine
blurred vision
burning, pain, or difficulty in urinating
chest pain
chills
cold sweats
cough
double vision or other eye or vision problems
fainting
fear or nervousness
feeling of constant movement of self or surroundings
high or low blood pressure
irregular or pounding heartbeat
loss of memory
mental depression
pain
pain in arms or legs
pounding in the ears
rapid weight gain
sensation of spinning
shortness of breath
slow or fast heartbeat
sore throat
sweating
tightness in chest
tingling of hands or feet
tingling, numbness, or prickly feelings
trouble in concentrating
troubled breathing
unusual weight gain or loss
vomiting
wheezing

Rare

Anxiety
buzzing or ringing in the ears
changes in vision
fever
headache
joint pain
loss of bladder control
muscle cramps, pain, or spasms
nasal congestion
runny nose
sneezing
trouble in swallowing
unusual urges

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Agitation
fatigue
grogginess
increase in unusual body movements, especially of the face or mouth
increased coughing
increased sweating
lack or loss of strength
nightmares

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abnormal dreams
acid or sour stomach
back pain
belching
decrease in sexual desire or performance
difficulty having a bowel movement (stool)
dryness of mouth
flushing
general feeling of discomfort or illness
heartburn or gas
hot flashes
indigestion
loss of appetite
tremor
weight loss
yawning

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Advanced,R

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Ropinirole

30/06/10

Generic Name: Ropinirole (roe-PIN-i-ROLE)
Brand Name: Requip

Ropinirole is used for:

Treating Parkinson disease and restless leg syndrome (RLS). It may also be used for other conditions as determined by your doctor.

Ropinirole is a dopamine agonist. It works in certain areas of the brain to reduce the symptoms of RLS and Parkinson disease.

Do NOT use Ropinirole if:

you are allergic to any ingredient in Ropinirole

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ropinirole:

Some medical conditions may interact with Ropinirole. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have heart problems, high or low blood pressure, liver disease, mental or mood problems, or a sleep disorder
if you smoke, drink alcohol, or have a personal or family history of addiction (eg, gambling, alcohol)

Some MEDICINES MAY INTERACT with Ropinirole. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
Entacapone or levodopa because the risk of hallucinations may be increased
Benzodiazepines (eg, diazepam), medicines for mental or mood problems (eg, antidepressants, antipsychotics), or medicines for sleep (eg, zolpidem) because the risk of severe drowsiness may be increased
Estrogens (eg, estradiol), fluvoxamine, or quinolones (eg, ciprofloxacin) because they may increase the risk of Ropinirole’s side effects
Butyrophenones (eg, haloperidol), metoclopramide, omeprazole, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease Ropinirole’s effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ropinirole may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ropinirole:

Use Ropinirole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Ropinirole. Talk to your pharmacist if you have questions about this information.
Take Ropinirole by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Do not suddenly stop taking Ropinirole or change your dose without checking with your doctor. Certain severe side effects (eg, abnormal thinking, confusion, fever, stiff muscles) may occur. If you need to stop Ropinirole or add a new medicine, your doctor will gradually lower your dose.
If you miss a dose of Ropinirole, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ropinirole.

Important safety information:

Ropinirole may cause dizziness, drowsiness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Ropinirole with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Ropinirole; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
Ropinirole may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
Some people who use Ropinirole may experience sudden onset of severe drowsiness or may even fall asleep during normal daily activities (eg, eating, talking, driving). This could occur without warning. If this happens, do not drive, operate machinery, or perform other possibly unsafe tasks while you use Ropinirole. Tell your doctor right away.
Some people have experienced new, unusual, or increased urges (eg, gambling, sexual urges) while using Ropinirole. Tell your doctor right away if you notice such effects.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Patients with Parkinson disease may have an increased risk of developing a certain type of skin cancer (melanoma). It is not known if Ropinirole also increases the risk of melanoma. You may need to have skin exams while you are using Ropinirole. Tell your doctor if you notice any unusual skin growths or a change in the appearance of a mole. Discuss any questions or concerns with your doctor.
If you are taking Ropinirole for RLS, contact your doctor if you experience new or worsening symptoms, especially in the early morning hours.
Use Ropinirole with caution in ELDERLY patients with Parkinson disease; they may be more sensitive to its effects, especially hallucinations.
Ropinirole should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ropinirole while you are pregnant. It is not known if Ropinirole is found in breast milk. Ropinirole may decrease breast milk production. Do not breast-feed while taking Ropinirole.

Possible side effects of Ropinirole:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; fatigue; headache; increased sweating; lightheadedness; loss of appetite; nausea; sore throat or flu-like symptoms; stomach pain or upset; tiredness; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; blood in the urine; blurred vision; chest pain; confusion; decreased coordination; fainting; falling asleep during the daytime or during normal activities (eg, conversations, eating); fast, slow, or irregular heartbeat; hallucinations; impotence; joint stiffness or pain; nightmares; numbness or tingling of the skin; severe or persistent headache or dizziness; shortness of breath; swelling of the arms or legs; uncontrolled muscle movements.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include agitation; chest pain; difficulty moving; facial muscle spasms; hallucinations; low blood pressure when sitting or lying down.

Proper storage of Ropinirole:

Store Ropinirole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep Ropinirole out of the reach of children and away from pets.

General information:

If you have any questions about Ropinirole, please talk with your doctor, pharmacist, or other health care provider.
Ropinirole is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ropinirole. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

Med-facts,R

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Rondec-DM

30/06/10

What is Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

What should I discuss with my healthcare provider before taking Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

kidney disease;
liver disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
a stomach ulcer or a stomach obstruction,
emphysema or chronic bronchitis; or
an enlarged prostate or urination problems.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

How should I take Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
confusion, hallucinations;
slow, shallow breathing;
urinating less than usual or not at all;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

blurred vision;
dry mouth;
nausea, stomach pain, constipation;
mild loss of appetite, stomach upset;
warmth, tingling, or redness under your skin;
feeling excited or restless;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness;
problems with memory or concentration; or
ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rondec-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant;
a diuretic (water pill);
medication to treat irritable bowel syndrome;
celecoxib (Celebrex);
cinacalcet (Sensipar);
imatinib (Gleevec);
quinidine (Quinaglute, Quinidex);
ranolazine (Ranexa)
ritonavir (Norvir);
sibutramine (Meridia);
terbinafine (Lamisil);
medicines to treat high blood pressure;
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

Comments (0)

Rondec-DM Drops

30/06/10

What is Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

What should I discuss with my healthcare provider before taking Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

kidney disease;
liver disease;
diabetes;
glaucoma;
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
a stomach ulcer or a stomach obstruction,
emphysema or chronic bronchitis; or
an enlarged prostate or urination problems.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

How should I take Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
confusion, hallucinations;
slow, shallow breathing;
urinating less than usual or not at all;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

blurred vision;
dry mouth;
nausea, stomach pain, constipation;
mild loss of appetite, stomach upset;
warmth, tingling, or redness under your skin;
feeling excited or restless;
sleep problems (insomnia);
restless or excitability (especially in children);
skin rash or itching;
dizziness, drowsiness;
problems with memory or concentration; or
ringing in your ears.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rondec-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

an antidepressant;
a diuretic (water pill);
medication to treat irritable bowel syndrome;
celecoxib (Celebrex);
cinacalcet (Sensipar);
imatinib (Gleevec);
quinidine (Quinaglute, Quinidex);
ranolazine (Ranexa)
ritonavir (Norvir);
sibutramine (Meridia);
terbinafine (Lamisil);
medicines to treat high blood pressure;
aspirin or salicylates (such as Disalcid, Doan’s Pills, Dolobid, Salflex, Tricosal, and others);
bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or
a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

Where can I get more information?

Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Concise,R

Comments (0)

Rondec-TR Controlled-Release Tablets

30/06/10

Generic Name: Carbinoxamine/Pseudoephedrine (kar-bi-NOX-ah-meen/soo-doe-eh-FED-rin)
Brand Name: Examples include Coldec D and Rondec-TR

Rondec-TR Controlled-Release Tablets are used for:

Relieving congestion, sneezing, and watery eyes due to colds, flu, or hay fever.

Rondec-TR Controlled-Release Tablets are an antihistamine and decongestant combination. It works by blocking the action of histamine and reducing the symptoms of an allergic reaction. It also relieves nasal congestion by causing vasoconstriction and shrinkage of the nasal mucous membranes and promoting drainage.

Do NOT use Rondec-TR Controlled-Release Tablets if:

you are allergic to any ingredient in Rondec-TR Controlled-Release Tablets
you have severe high blood pressure, severe heart disease (coronary artery disease, ischemic heart disease), angle-closure glaucoma, or a peptic ulcer, or if you are unable to urinate due to bladder problems (urinary retention)
you are having an asthma attack
you are taking sodium oxybate (GHB), or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Rondec-TR Controlled-Release Tablets:

Some medical conditions may interact with Rondec-TR Controlled-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have asthma; diabetes; heart disease; high blood pressure; increased inner eye pressure; a blockage of your stomach, intestines, or bladder; an overactive thyroid; difficulty urinating; an enlarged prostate; or seizures

Some MEDICINES MAY INTERACT with Rondec-TR Controlled-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

Barbiturates (eg, phenobarbital), furazolidone, MAO inhibitors (eg, phenelzine), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, antacids) because side effects, such as increased drowsiness, headache, high blood pressure, or elevated body temperature, may occur
Sodium oxybate (GHB) because side effects, such as an increase in sleep duration and drowsiness leading to unconsciousness or coma, may occur
Bromocriptine or droxidopa because the actions and side effects of these medicines may be increased
Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Rondec-TR Controlled-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Rondec-TR Controlled-Release Tablets:

Use Rondec-TR Controlled-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Rondec-TR Controlled-Release Tablets may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
Swallow Rondec-TR Controlled-Release Tablets whole. Do not crush or chew before swallowing. Some brands of Rondec-TR Controlled-Release Tablets may be broken in half before they are taken. If you have difficulty swallowing the whole tablet, ask your pharmacist if your brand may be broken in half.
If you miss a dose of Rondec-TR Controlled-Release Tablets and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rondec-TR Controlled-Release Tablets.

Important safety information:

Rondec-TR Controlled-Release Tablets may cause drowsiness, dizziness, or change in vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Rondec-TR Controlled-Release Tablets. Using Rondec-TR Controlled-Release Tablets alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Rondec-TR Controlled-Release Tablets.
Do not take diet or appetite control medicines while you are taking Rondec-TR Controlled-Release Tablets without checking with your doctor.
Rondec-TR Controlled-Release Tablets contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
Use Rondec-TR Controlled-Release Tablets with caution in the ELDERLY because they may be more sensitive to its effects, especially sleeplessness.
Use Rondec-TR Controlled-Release Tablets with extreme caution in CHILDREN younger than 12 months of age. Safety and effectiveness in this age group have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Rondec-TR Controlled-Release Tablets, discuss with your doctor the benefits and risks of using Rondec-TR Controlled-Release Tablets during pregnancy. It is unknown if Rondec-TR Controlled-Release Tablets are excreted in breast milk. If you are or will be breast-feeding while you are using Rondec-TR Controlled-Release Tablets, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Rondec-TR Controlled-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Appetite loss; diarrhea; dizziness; drowsiness; dry mouth, throat, or nose; headache; heartburn; nausea; nervousness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty breathing; difficulty urinating; double vision; fast or irregular heartbeat; frequent or painful urination; hallucinations; seizures; severe headache and dizziness; severe nervousness; tremor; weakness.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include decreased mental alertness; fast or irregular heartbeat; fever; hallucinations; nausea; seizures; sleeplessness; sweating; trouble breathing; unusual drowsiness or dizziness; tremors; vomiting.

Proper storage of Rondec-TR Controlled-Release Tablets:

Store Rondec-TR Controlled-Release Tablets at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep Rondec-TR Controlled-Release Tablets out of the reach of children and away from pets.

General information:

If you have any questions about Rondec-TR Controlled-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
Rondec-TR Controlled-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Rondec-TR Controlled-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

Med-facts,R

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Drugs & Medications:A-Z

Recent Posts

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30/06/10

What is ropivacaine?

What is the most important information I should know about ropivacaine?

What should I discuss with my health care provider before receiving ropivacaine?

How is ropivacaine given?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid after receiving ropivacaine?

Ropivacaine side effects

Ropivacaine Dosing Information

What other drugs will affect ropivacaine?

Where can I get more information?

30/06/10

Uses For ropivacaine

Before Using ropivacaine

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of ropivacaine

Dosing

Precautions While Using ropivacaine

ropivacaine Side Effects

30/06/10

What is Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

What is the most important information I should know about Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

What should I discuss with my healthcare provider before taking Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

How should I take Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

What other drugs will affect Rondex-DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Where can I get more information?

30/06/10

What is Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

What is the most important information I should know about Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

What should I discuss with my healthcare provider before taking Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

How should I take Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while taking Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

What other drugs will affect Rondex-DM Drops (chlorpheniramine, dextromethorphan, and phenylephrine)?

Where can I get more information?

30/06/10

What is Ronoxidil (minoxidil topical)?

What is the most important information I should know about Ronoxidil (minoxidil topical)?

What should I discuss with my healthcare provider before using Ronoxidil (minoxidil topical)?

How should I use Ronoxidil (minoxidil topical)?

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using Ronoxidil (minoxidil topical)?

Ronoxidil (minoxidil topical) side effects

What other drugs will affect Ronoxidil (minoxidil topical)?

Where can I get more information?

30/06/10

Uses For ropinirole

Before Using ropinirole

Allergies

Pediatric

Geriatric

Pregnancy

Breast Feeding

Interactions with Medicines

Interactions with Food/Tobacco/Alcohol

Other Medical Problems

Proper Use of ropinirole

Dosing

Missed Dose

Storage

Precautions While Using ropinirole

ropinirole Side Effects