TYE-foid Vi pol-ee-SAK-a-ride VAX-een
Commonly used brand name(s):
In the U.S.
- Typhim Vi
- Typhoid Vi Polysaccharide Vaccine
Available Dosage Forms:
- Solution
- Injectable
Therapeutic Class: Vaccine
Uses For typhoid vi polysaccharide vaccine
Typhoid fever is a serious disease that can cause death. It is caused by a germ called Salmonella typhi, and is spread most often through infected food or water. Typhoid may also be spread by close person-to-person contact with infected persons (such as occurs with persons living in the same household). Some infected persons do not appear to be sick, but they can still spread the germ to others.
Typhoid fever is very rare in the U.S. and other areas of the world that have good water and sewage (waste) systems. However, it is a problem in parts of the world that do not have such systems. If you are traveling to certain countries or remote, out-of-the-way areas, typhoid vaccine will help protect you from typhoid fever. The U.S. Centers for Disease Control (CDC) currently recommend caution in the following areas of the world:
- Africa
- Asia
- Latin America
Typhoid vaccine given by injection helps prevent typhoid fever, but does not provide 100% protection. Therefore, it is very important to avoid infected persons and food and water that may be infected, even if you have received the vaccine.
To get the best possible protection against typhoid, you should receive the vaccine at least 1 week before you travel to areas where you may be exposed to typhoid.
If you will be traveling regularly to parts of the world where typhoid is a problem, you should get a booster (repeat) dose of the vaccine every 2 years.
Typhoid vaccine is to be used only by or under the supervision of a doctor.
Before Using typhoid vi polysaccharide vaccine
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to typhoid vi polysaccharide vaccine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Typhoid Vi polysaccharide vaccine is not recommended for infants and children younger than 2 years of age. For children 2 years of age and over, this vaccine is not expected to cause different side effects or problems than it does in adults.
Geriatric
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of typhoid vaccine in the elderly with use in other age groups, this vaccine is not expected to cause different side effects or problems in older people than it does in younger adults.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Tacrolimus
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
- Previous sensitivity reaction to typhoid vaccine—Use of typhoid vaccine is not recommended
- Severe illness with fever—The symptoms of the condition may be confused with the side effects of the vaccine
Proper Use of typhoid vi polysaccharide vaccine
Dosing
The dose of typhoid vi polysaccharide vaccine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of typhoid vi polysaccharide vaccine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
The dose of typhoid Vi polysaccharide vaccine is the same for all patients 2 years of age and older. For infants and children up to two years of age, the use of typhoid Vi polysaccharide vaccine is not recommended.
- For injection dosage form:
- For prevention of typhoid fever:
- Adults and children 2 years of age and older—One dose injected into a muscle.
- Children up to 2 years of age—Use is not recommended.
- For prevention of typhoid fever:
typhoid vi polysaccharide vaccine Side Effects
Along with its needed effects, a vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. It is very important that you tell your doctor about any side effects that occur after a dose of typhoid vaccine, even though the side effect may have gone away without treatment. Some types of side effects may mean that you should not receive any more doses of typhoid vaccine.
Check with your doctor immediately if any of the following side effects occur:
Rare
- Difficulty in breathing or swallowing
- hives
- itching, especially of feet or hands
- reddening of skin, especially around ears
- swelling of eyes, face, or inside of nose
- unusual tiredness or weakness (sudden and severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Fever
- general feeling of discomfort or illness
- headache
- muscle pain
- pain, redness, or swelling at place of injection
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Typhoid Vi Polysaccharide Vaccine
30/06/10
Generic Name: Typhoid Vi Polysaccharide Vaccine (TIE-foyd PAHL-ee-SACK-ah-ride)
Brand Name: Typhim Vi
Typhoid Vi Polysaccharide Vaccine is used for:
Preventing typhoid fever in persons 2 years of age and older who are at increased risk because they are traveling to an area where this infection is more common, have been in contact with infected individuals, or work in an environment that increases their risk (eg, lab work).
Typhoid Vi Polysaccharide Vaccine is a vaccine. It works by stimulating the immune system of the person who receives the vaccine to make their own protective antibodies against this disease.
Do NOT use Typhoid Vi Polysaccharide Vaccine if:
- you are allergic to any ingredient in Typhoid Vi Polysaccharide Vaccine
- you are already infected or are a carrier of typhoid
Contact your doctor or health care provider right away if any of these apply to you.
Before using Typhoid Vi Polysaccharide Vaccine:
Some medical conditions may interact with Typhoid Vi Polysaccharide Vaccine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a weakened immune system or are unable to make antibodies due to HIV infection, cancer, or cancer therapy (eg, chemo or radiation) or you are taking medicines that suppress the immune system (eg, certain cancer medicines, corticosteroids such as methylprednisolone, cyclosporine)
Some MEDICINES MAY INTERACT with Typhoid Vi Polysaccharide Vaccine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Immunosuppressives (eg, certain cancer medicines, corticosteroids such as methylprednisolone, cyclosporine) because the effectiveness of Typhoid Vi Polysaccharide Vaccine may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Typhoid Vi Polysaccharide Vaccine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Typhoid Vi Polysaccharide Vaccine:
Use Typhoid Vi Polysaccharide Vaccine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Typhoid Vi Polysaccharide Vaccine is administered as an injection at your doctor’s office, hospital, or clinic.
- This vaccine should be given at least 2 weeks before being exposed to typhoid fever.
- If Typhoid Vi Polysaccharide Vaccine contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
- If you miss a dose of Typhoid Vi Polysaccharide Vaccine, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use Typhoid Vi Polysaccharide Vaccine.
Important safety information:
- Typhoid Vi Polysaccharide Vaccine should be given 2 weeks prior to expected exposure.
- Side effects usually occur within 48 hours after receiving this vaccine. Contact your health care provider if any of the following symptoms persist for more than 2 days: tenderness, redness, pain, or hardening at the injection site; general body discomfort; headache; muscle pain; nausea; diarrhea; fever.
- Travelers should continue to take other precautions to avoid contact with possibly infected food or water.
- It is recommended that you receive another single dose of Typhoid Vi Polysaccharide Vaccine every 2 years if you continue to be exposed to typhoid fever.
- Typhoid Vi Polysaccharide Vaccine is not recommended for use in CHILDREN younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Typhoid Vi Polysaccharide Vaccine during pregnancy. It is unknown if Typhoid Vi Polysaccharide Vaccine is excreted in breast milk. If you are or will be breast-feeding while you are using Typhoid Vi Polysaccharide Vaccine, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of Typhoid Vi Polysaccharide Vaccine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; fever; general body discomfort; headache; muscle pain; nausea; tenderness, pain, redness, swelling, and hardening at the injection site.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; giant hives; hoarseness; shock.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.
Proper storage of Typhoid Vi Polysaccharide Vaccine:
Typhoid Vi Polysaccharide Vaccine is usually handled and stored by a health care provider. If you are using Typhoid Vi Polysaccharide Vaccine at home, store Typhoid Vi Polysaccharide Vaccine as directed by your pharmacist or health care provider.
General information:
- If you have any questions about Typhoid Vi Polysaccharide Vaccine, please talk with your doctor, pharmacist, or other health care provider.
- Typhoid Vi Polysaccharide Vaccine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Typhoid Vi Polysaccharide Vaccine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
typhoid vaccine (live), oral
30/06/10
Generic Name: typhoid vaccine (live), oral (TYE foid vax EEN)
Brand Names: Vivotif Berna
What is typhoid vaccine?
Typhoid (also called “typhoid fever”) is a serious disease caused by Salmonella typhi bacteria. Typhoid can be fatal if left untreated.
Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.
Untreated typhoid infection may lead to kidney failure, or intestinal bleeding caused by perforation (forming of a hole), which can be fatal. If the infection spreads to the gallbladder, the infected person may become a chronic carrier of the bacteria that causes typhoid. A carrier may have no symptoms but is capable of spreading the infection to others.
Typhoid is spread through contact with the stool (bowel movements) of a person infected with the bacteria. This usually occurs by eating food or drinking water that has become contaminated with feces from an infected person. Once in the digestive tract, typhoid infection can spread to the blood and other parts of the body.
Typhoid fever is most common in non-industrialized parts of the world, especially Asia, Africa, and Central or South America. People who travel to those regions are at risk of coming into contact with the disease.
The typhoid vaccine is used to help prevent this disease in adults and children who are at least 6 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for people who travel to areas where the disease is common.
This vaccine works by exposing you to a small amount of the bacteria, which causes your body to develop immunity to the disease.
Typhoid vaccine will not treat an active infection that has already developed in the body, and will not prevent any disease caused by bacteria other than Salmonella typhi.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
What is the most important information I should know about typhoid vaccine?
You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past, or if you have fever with any type of infection or illness, or a weak immune system caused by disease or by using certain medicines such as chemotherapy. Typhoid vaccine should not be used in a person who is a typhoid carrier.
Before you receive this vaccine, tell the doctor if you have any illness with vomiting or diarrhea, if you are taking an antibiotic or sulfa drug (Azulfidine, Bactrim, Cotrim, Gantrisin, Septra, SMX-TMP, Sulfazine), or if you plan to start taking an anti-malaria medication within 10 days after receiving typhoid vaccine.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, the doctor may ask you to wait until you get better before you can receive the vaccine.
The typhoid oral vaccine is given in a series of 4 capsules that are taken 1 per day on alternating days (days 1, 3, 5, and 7). On this alternating-day schedule, you will take 1 capsule every 48 hours for 7 days. You must take each capsule according to the recommended schedule for this vaccine to be effective.
You should complete all doses at least 1 week before your scheduled travel or possible exposure to typhoid.
You must keep typhoid vaccine capsules cold when not in use. Once you receive the capsules from your doctor or pharmacy, take them directly home and place them in the refrigerator. Keep each capsule in the foil blister pack in the refrigerator until you are ready to take it. Do not allow the capsules to freeze.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
In addition to receiving typhoid vaccine, take precautions while traveling such as avoiding raw fruits or vegetables that cannot be peeled, drinks that contain ice, flavored ices that may have been made with contaminated water, unbottled or unboiled water, or any food or beverage purchased from a street vendor.
What should I discuss with my healthcare provider before receiving typhoid vaccine?
Typhoid vaccine should not be used in a person who is a typhoid carrier. You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past, or if you have:
-
fever with any type of infection or illness;
-
a weak immune system caused by disease such as HIV/AIDS or cancer; or
-
a weak immune system caused by using certain medicines such as chemotherapy.
You may not be able to receive this vaccine if you have:
-
stomach flu or any illness with vomiting or diarrhea;
-
if you are taking an antibiotic, especially a sulfa drug such as sulfasalazine (Azulfidine, Sulfazine), sulfamethoxazole (Bactrim, Cotrim, Septra, SMX-TMP), or sulfisoxazole (Gantrisin); or
-
if you plan to start taking an anti-malaria medication within 10 days after receiving a typhoid oral vaccine.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, the doctor may ask you to wait until you get better before you can receive the vaccine.
Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with typhoid. It is not known whether typhoid vaccine passes into breast milk, or if it could harm a nursing baby. Do not receive this vaccine without telling your doctor if you are breast-feeding a baby.
How is typhoid vaccine given?
Typhoid vaccine is recommended for adults and children in the following situations:
-
people who travel to countries where typhoid fever is common;
-
people who will have long-term exposure to food or water that may be contaminated with typhoid;
-
people who live with someone who is a typhoid carrier; and
-
laboratory workers who may come into contact with Salmonella typhi in a work setting.
The typhoid oral vaccine is given in a series of 4 capsules that are taken 1 per day on alternating days (days 1, 3, 5, and 7). On this alternating-day schedule, you will take 1 capsule every 48 hours for 7 days. You must take each capsule according to the recommended schedule for this vaccine to be effective.
You should complete all doses at least 1 week before your scheduled travel or possible exposure to typhoid.
You must keep typhoid vaccine capsules cold when not in use. Once you receive the capsules from your doctor or pharmacy, take them directly home and place them in the refrigerator. Keep each capsule in the foil blister pack in the refrigerator until you are ready to take it. Do not allow the capsules to freeze. Take the capsule on an empty stomach, at least 1 hour before a meal.
Swallow the capsule as quickly as possible after placing it in your mouth. Take with a full glass of cold or lukewarm water or other beverage. Do not use warm or hot drinks such as coffee, tea, or warm milk. The liquid you use to help swallow the typhoid vaccine capsule should not be warmer than your body temperature (98.6 degrees F).
Do not crush, chew, or break a typhoid vaccine capsule. Swallow the pill whole. The enteric-coated pill has a special coating to release the vaccine slowly into your body. Breaking the pill could damage this coating.
The complete series of 4 vaccine capsules should provide protection against typhoid for up to 5 years. Another series of 4 capsules is then recommended every 5 years during possible exposure to typhoid. Your individual booster schedule may be different from these guidelines. Follow your doctor’s instructions or the schedule recommended by the Centers for Disease Control and Prevention (CDC).
Be sure you receive all recommended doses of this vaccine. If you do not receive the full series of capsules every 5 years during continued exposure, you may not be fully protected against the disease.
Wash your hands often to help prevent typhoid when you are in an area where contamination is possible.
What happens if I miss a dose?
Contact your doctor if you forget to take a capsule on the scheduled day. You may need to start over to make sure you are fully protected against the disease.
Be sure to receive another series of 4 capsules every 5 years during continued exposure to typhoid.
What happens if I overdose?
An overdose of this vaccine is unlikely to occur when taken as directed.
What should I avoid before or after getting typhoid vaccine?
In addition to receiving typhoid vaccine, take precautions while traveling to further prevent coming into contact with bacteria that cause typhoid fever:
-
Avoid eating leafy vegetables such as spinach or lettuce, which are harder to wash properly.
-
Avoid eating raw fruits or vegetables that cannot be peeled, or that have been peeled by another person.
-
Avoid drinks that contain ice, or frozen treats and flavored ices that may have been made with contaminated water.
-
Avoid eating foods you have not cooked or prepared yourself. Use clean surfaces and utensils when preparing food.
-
Drink only bottled water (carbonated is best) or water that has been boiled for at least 1 minute.
-
Avoid any food or beverage purchased from a street vendor.
Typhoid vaccine side effects
You should not receive a booster dose if you had a life-threatening allergic reaction after taking a typhoid vaccine capsule.
Becoming infected with typhoid is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects include:
-
low fever;
-
headache;
-
nausea, vomiting, diarrhea, stomach pain; or
-
mild skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Typhoid vaccine (live), oral Dosing Information
Usual Adult Dose for Typhoid Prophylaxis:
One capsule orally 1 hour before a meal with a cold or lukewarm drink [temperature not to exceed body temperature, e.g., 37 °C (98.6 °F)] on alternate days, e.g., days 1, 3, 5 and 7.
Immunization with all 4 doses should be completed at least 1 week prior to potential exposure to Salmonella typhi.
Usual Pediatric Dose for Typhoid Prophylaxis:
>= 6 years: One capsule orally 1 hour before a meal with a cold or lukewarm drink [temperature not to exceed body temperature, e.g., 37 °C (98.6 °F)] on alternate days, e.g., days 1, 3, 5 and 7.
Immunization with all 4 doses should be completed at least 1 week prior to potential exposure to Salmonella typhi.
What other drugs will affect typhoid vaccine?
Before receiving this vaccine, tell the doctor about all other vaccines you have recently received.
You should not take an anti-malaria medication called proguanil (Malarone) for at least 10 days after you have received your last dose of typhoid vaccine. Proguanil may make typhoid vaccine less effective.
There may be other drugs that can affect this vaccine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your doctor or pharmacist may have information about this vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:43:35 PM.
Generic Name: Typhoid Vaccine Live (TIE-foyd)
Brand Name: Vivotif Berna Vaccine
Typhoid Vaccine Live Delayed-Release Capsules are used for:
Preventing typhoid fever in persons 6 years old and older who are at increased risk because they are traveling to an area where this infection is more common, have been in contact with infected individuals, or work in an environment that increases their risk (eg, lab work).
Typhoid Vaccine Live Delayed-Release Capsules are a vaccine. It works by stimulating the body to produce antibodies against typhoid fever.
Do NOT use Typhoid Vaccine Live Delayed-Release Capsules if:
- you are allergic to any ingredient in Typhoid Vaccine Live Delayed-Release Capsules
- you have a current infection, cancer, fever, persistent vomiting or diarrhea, other stomach illness, or HIV or another condition that weakens the immune system
- you are taking a sulfonamide (eg, sulfamethoxazole), another antibiotic (eg, penicillin), or a medicine that weakens the immune system (eg, cyclosporine, certain cancer medicines)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Typhoid Vaccine Live Delayed-Release Capsules:
Some medical conditions may interact with Typhoid Vaccine Live Delayed-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have an infection or fever, chronic diarrhea, an illness affecting the stomach or intestines, undiagnosed rectal hemorrhage, or persistent vomiting, or you are receiving chemotherapy or radiation therapy
Some MEDICINES MAY INTERACT with Typhoid Vaccine Live Delayed-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antibiotics (eg, penicillin), corticosteroids (eg, prednisone), immunosuppressants (eg, certain cancer medicines, cyclosporine), or sulfonamides (eg, sulfamethoxazole) because they may decrease Typhoid Vaccine Live Delayed-Release Capsules’s effectiveness
- Proguanil because it may decrease Typhoid Vaccine Live Delayed-Release Capsules’s effectiveness. You should not take proguanil for at least 10 days after your last dose of Typhoid Vaccine Live Delayed-Release Capsules. Discuss any questions with your doctor
This may not be a complete list of all interactions that may occur. Ask your health care provider if Typhoid Vaccine Live Delayed-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Typhoid Vaccine Live Delayed-Release Capsules:
Use Typhoid Vaccine Live Delayed-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Typhoid Vaccine Live Delayed-Release Capsules with a cold or lukewarm drink 1 hour before or 2 hours after a meal.
- Swallow Typhoid Vaccine Live Delayed-Release Capsules whole. Do not break, crush, or chew before swallowing.
- Do not take cracked or broken capsules.
- Do not drink alcohol within 2 hours of taking Typhoid Vaccine Live Delayed-Release Capsules.
- Do not forget to skip a day between capsules. Take a capsule EVERY OTHER DAY as directed by your doctor.
- For Typhoid Vaccine Live Delayed-Release Capsules to be effective, you must complete all 4 doses at least 1 week before exposure to typhoid fever.
- If you miss a dose of Typhoid Vaccine Live Delayed-Release Capsules, take it as soon as possible. If you do not remember until the next day, take the dose as soon as possible and reschedule your doses from that day.
Ask your health care provider any questions you may have about how to use Typhoid Vaccine Live Delayed-Release Capsules.
Important safety information:
- Notify your doctor if you experience diarrhea, vomiting, or flu-like symptoms after taking Typhoid Vaccine Live Delayed-Release Capsules.
- This vaccine helps prevent typhoid fever, but does not provide 100% protection. It is important to also avoid infected people, food, and water.
- It is recommended that you receive another 4 doses of Typhoid Vaccine Live Delayed-Release Capsules every 5 years if you continue to be exposed to typhoid fever.
- Typhoid Vaccine Live Delayed-Release Capsules are not recommended for use in CHILDREN younger than 6 years of age; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Typhoid Vaccine Live Delayed-Release Capsules during pregnancy. It is not known if Typhoid Vaccine Live Delayed-Release Capsules are found in breast milk. If you are or will be breast-feeding while you use Typhoid Vaccine Live Delayed-Release Capsules, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Typhoid Vaccine Live Delayed-Release Capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; fever; headache; muscle pain; nausea; stomach cramps or pain; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; unusual hoarseness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.
Proper storage of Typhoid Vaccine Live Delayed-Release Capsules:
Store Typhoid Vaccine Live Delayed-Release Capsules in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), at all times. Do not freeze. Keep Typhoid Vaccine Live Delayed-Release Capsules out of the reach of children and away from pets.
General information:
- If you have any questions about Typhoid Vaccine Live Delayed-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
- Typhoid Vaccine Live Delayed-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Typhoid Vaccine Live Delayed-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
TYE-foid VAX-een, in-AK-ti-vay-ted
Uses For typhoid vaccine, inactivated
Typhoid fever is a serious disease that can cause death. It is caused by a germ called Salmonella typhi and is spread most often through infected food or water. Typhoid may also be spread by close person-to-person contact with infected persons (such as occurs with persons living in the same household). Some infected persons do not appear to be sick, but they can still spread the germ to others.
Typhoid fever is rare in the U.S. and in other areas of the world that have good water and sewage (waste) systems. However, it is a problem in parts of the world that do not have such systems. If you are traveling to certain countries, or to remote, out-of-the-way areas, typhoid vaccine will help protect you from typhoid fever. The U.S. Centers for Disease Control (CDC) currently recommend caution in the following areas of the world:
- Africa
- Asia
- Latin America
Typhoid vaccine given by injection helps prevent typhoid fever but does not provide 100% protection. Therefore, it is very important to avoid infected persons and food and water that may be infected, even if you have received the vaccine.
To get the best possible protection against typhoid, you should complete the vaccine dosing schedule at least 1 week before you travel to areas where you may be exposed to typhoid.
Also, if you will be traveling regularly to parts of the world where typhoid is a problem, you should get a booster (repeat) dose of the vaccine every 3 years.
Typhoid vaccine is to be used only by or under the supervision of a doctor.
Before Using typhoid vaccine, inactivated
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to typhoid vaccine, inactivated or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Typhoid vaccine is not recommended for infants and children up to 6 months of age. For infants and children 6 months of age and over, this vaccine is not expected to cause different side effects or problems than it does in adults.
Geriatric
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of typhoid vaccine in the elderly with use in other age groups, this vaccine is not expected to cause different side effects or problems in older people than it does in younger adults.
Interactions with Medicines
Receiving this vaccine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Tacrolimus
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
- Previous sensitivity reaction to typhoid vaccine—Use of typhoid vaccine is not recommended
- Severe illness with fever—The symptoms of the condition may be confused with the side effects of the vaccine
Proper Use of typhoid vaccine, inactivated
It is important that you complete the full vaccine dosing schedule. If all the doses are not taken or if doses are not taken at the correct times, the vaccine may not work properly.
Dosing
The dose of typhoid vaccine, inactivated will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of typhoid vaccine, inactivated. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
typhoid vaccine, inactivated Side Effects
Along with its needed effects, a vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. It is very important that you tell your doctor about any side effects that occur after a dose of typhoid vaccine, even though the side effect may have gone away without treatment. Some types of side effects may mean that you should not receive any more doses of typhoid vaccine.
Check with your doctor immediately if any of the following side effects occur:
Rare
- Chest pain
- difficulty in breathing or swallowing
- hives
- itching, especially of feet or hands
- joint pain
- reddening of skin, especially around ears
- swelling of eyes, face, or inside of nose
- unusual tiredness or weakness (sudden and severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Fever
- general feeling of discomfort or illness
- headache
- muscle pain
- pain, redness, or swelling at place of injection
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.
Generic Name: Typhoid Vaccine Live (TIE-foyd)
Brand Name: Vivotif Berna Vaccine
Typhoid Vaccine Delayed-Release Capsules are used for:
Preventing typhoid fever in persons 6 years old and older who are at increased risk because they are traveling to an area where this infection is more common, have been in contact with infected individuals, or work in an environment that increases their risk (eg, lab work).
Typhoid Vaccine Delayed-Release Capsules are a vaccine. It works by stimulating the body to produce antibodies against typhoid fever.
Do NOT use Typhoid Vaccine Delayed-Release Capsules if:
- you are allergic to any ingredient in Typhoid Vaccine Delayed-Release Capsules
- you have a current infection, cancer, fever, persistent vomiting or diarrhea, other stomach illness, or HIV or another condition that weakens the immune system
- you are taking a sulfonamide (eg, sulfamethoxazole), another antibiotic (eg, penicillin), or a medicine that weakens the immune system (eg, cyclosporine, certain cancer medicines)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Typhoid Vaccine Delayed-Release Capsules:
Some medical conditions may interact with Typhoid Vaccine Delayed-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have an infection or fever, chronic diarrhea, an illness affecting the stomach or intestines, undiagnosed rectal hemorrhage, or persistent vomiting, or you are receiving chemotherapy or radiation therapy
Some MEDICINES MAY INTERACT with Typhoid Vaccine Delayed-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antibiotics (eg, penicillin), corticosteroids (eg, prednisone), immunosuppressants (eg, certain cancer medicines, cyclosporine), or sulfonamides (eg, sulfamethoxazole) because they may decrease Typhoid Vaccine Delayed-Release Capsules’s effectiveness
- Proguanil because it may decrease Typhoid Vaccine Delayed-Release Capsules’s effectiveness. You should not take proguanil for at least 10 days after your last dose of Typhoid Vaccine Delayed-Release Capsules. Discuss any questions with your doctor
This may not be a complete list of all interactions that may occur. Ask your health care provider if Typhoid Vaccine Delayed-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Typhoid Vaccine Delayed-Release Capsules:
Use Typhoid Vaccine Delayed-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Typhoid Vaccine Delayed-Release Capsules with a cold or lukewarm drink 1 hour before or 2 hours after a meal.
- Swallow Typhoid Vaccine Delayed-Release Capsules whole. Do not break, crush, or chew before swallowing.
- Do not take cracked or broken capsules.
- Do not drink alcohol within 2 hours of taking Typhoid Vaccine Delayed-Release Capsules.
- Do not forget to skip a day between capsules. Take a capsule EVERY OTHER DAY as directed by your doctor.
- For Typhoid Vaccine Delayed-Release Capsules to be effective, you must complete all 4 doses at least 1 week before exposure to typhoid fever.
- If you miss a dose of Typhoid Vaccine Delayed-Release Capsules, take it as soon as possible. If you do not remember until the next day, take the dose as soon as possible and reschedule your doses from that day.
Ask your health care provider any questions you may have about how to use Typhoid Vaccine Delayed-Release Capsules.
Important safety information:
- Notify your doctor if you experience diarrhea, vomiting, or flu-like symptoms after taking Typhoid Vaccine Delayed-Release Capsules.
- This vaccine helps prevent typhoid fever, but does not provide 100% protection. It is important to also avoid infected people, food, and water.
- It is recommended that you receive another 4 doses of Typhoid Vaccine Delayed-Release Capsules every 5 years if you continue to be exposed to typhoid fever.
- Typhoid Vaccine Delayed-Release Capsules are not recommended for use in CHILDREN younger than 6 years of age; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Typhoid Vaccine Delayed-Release Capsules during pregnancy. It is not known if Typhoid Vaccine Delayed-Release Capsules are found in breast milk. If you are or will be breast-feeding while you use Typhoid Vaccine Delayed-Release Capsules, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Typhoid Vaccine Delayed-Release Capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; fever; headache; muscle pain; nausea; stomach cramps or pain; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty swallowing; unusual hoarseness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.
Proper storage of Typhoid Vaccine Delayed-Release Capsules:
Store Typhoid Vaccine Delayed-Release Capsules in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C), at all times. Do not freeze. Keep Typhoid Vaccine Delayed-Release Capsules out of the reach of children and away from pets.
General information:
- If you have any questions about Typhoid Vaccine Delayed-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
- Typhoid Vaccine Delayed-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Typhoid Vaccine Delayed-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Generic Name: typhoid vaccine (inactivated), injection (TYE foid vax EEN)
Brand Names: Typhim VI
What is typhoid vaccine?
Typhoid (also called “typhoid fever”) is a serious disease caused by Salmonella typhi bacteria. Typhoid can be fatal if left untreated.
Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.
Untreated typhoid infection may lead to kidney failure, or intestinal bleeding caused by perforation (forming of a hole), which can be fatal. If the infection spreads to the gallbladder, the infected person may become a chronic carrier of the bacteria that causes typhoid. A carrier may have no symptoms but is capable of spreading the infection to others.
Typhoid is spread through contact with the stool (bowel movements) of a person infected with the bacteria. This usually occurs by eating food or drinking water that has become contaminated with feces from an infected person. Once in the digestive tract, typhoid infection can spread to the blood and other parts of the body.
Typhoid fever is most common in non-industrialized parts of the world, especially Asia, Africa, and Central or South America. People who travel to those regions are at risk of coming into contact with the disease.
The typhoid vaccine is used to help prevent this disease in adults and children who are at least 2 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for people who travel to areas where the disease is common.
This vaccine works by exposing you to a small dose of an extract from the bacteria, which causes your body to develop immunity to the disease.
Typhoid vaccine will not treat an active infection that has already developed in the body, and will not prevent any disease caused by bacteria other than Salmonella typhi.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
What is the most important information I should know about typhoid vaccine?
You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past. Typhoid vaccine should not be used in a person who is a typhoid carrier.
Before you receive this vaccine, tell the doctor if you have a bleeding or blood clotting disorder (such as hemophilia), a weak immune system caused by disease or by taking certain medicines, or if you are taking a blood thinner or receiving cancer treatments or radiation.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
In addition to receiving typhoid vaccine, take precautions while traveling such as avoiding raw fruits or vegetables that cannot be peeled, drinks that contain ice, flavored ices that may have been made with contaminated water, unbottled or unboiled water, or any food or beverage purchased from a street vendor.
Keep track of any and all side effects you have after receiving a typhoid vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
What should I discuss with my healthcare provider before receiving typhoid vaccine?
Typhoid vaccine should not be used in a person who is a typhoid carrier. You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past.
Typhoid vaccine may not work as well in someone who has a weak immune system caused by disease or by taking certain medicines or receiving cancer treatments, including radiation.
Before you receive this vaccine, tell the doctor if you have a bleeding or blood clotting disorder such as hemophilia or easy bruising.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, the doctor may ask you to wait until you get better before you can receive the vaccine.
Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with typhoid. It is not known whether typhoid vaccine passes into breast milk, or if it could harm a nursing baby. Do not receive this vaccine without telling your doctor if you are breast-feeding a baby.
How is typhoid vaccine given?
This vaccine is given as an injection (shot) into a muscle. You will receive this injection in a doctor’s office or other clinic setting.
The typhoid vaccine is given as a single injection. A booster dose is then recommended every 2 years during possible exposure to typhoid. Your individual booster schedule may be different from these guidelines. Follow your doctor’s instructions or the schedule recommended by the Centers for Disease Control and Prevention (CDC).
If you are being vaccinated before traveling, you should receive the typhoid vaccine at least 2 weeks before your scheduled departure.
Typhoid vaccine is recommended for adults and children in the following situations:
-
people who travel to countries where typhoid fever is common;
-
people who will have long-term exposure to food or water that may be contaminated with typhoid;
-
people who live with someone who is a typhoid carrier; and
-
laboratory workers who may come into contact with Salmonella typhi in a work setting.
Wash your hands often to help prevent typhoid when you are in an area where contamination is possible.
What happens if I miss a dose?
Contact your doctor if you will miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.
Be sure to receive a booster dose of this vaccine every 2 years during continued exposure to typhoid. If you do not receive the booster every 2 years, you may not be fully protected against the disease.
What happens if I overdose?
An overdose of this vaccine is unlikely to occur.
What should I avoid before or after getting typhoid vaccine?
In addition to receiving typhoid vaccine, take precautions while traveling to further prevent coming into contact with bacteria that cause typhoid fever:
-
Avoid eating leafy vegetables such as spinach or lettuce, which are harder to wash properly.
-
Avoid eating raw fruits or vegetables that cannot be peeled, or that have been peeled by another person.
-
Avoid drinks that contain ice, or frozen treats and flavored ices that may have been made with contaminated water.
-
Avoid eating foods you have not cooked or prepared yourself. Use clean surfaces and utensils when preparing food.
-
Drink only bottled water (carbonated is best) or water that has been boiled for at least 1 minute.
-
Avoid any food or beverage purchased from a street vendor.
Typhoid vaccine side effects
You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot. Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with typhoid is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
-
fever, swollen glands, rash or itching, joint pain, or general ill feeling;
-
tremors or shaking; or
-
feeling like you might pass out.
Less serious side effects include:
-
pain, tenderness, redness, swelling, or a hard lump where the shot was given;
-
low fever;
-
headache;
-
muscle or joint pain;
-
nausea, diarrhea, stomach pain; or
-
weakness.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Typhoid vaccine (inactivated), injection Dosing Information
Usual Adult Dose for Typhoid Prophylaxis:
0.5 mL IM once in the deltoid.
The vaccine should be given at least 2 weeks before potential exposure to S typhi.
Booster: 0.5 mL IM every 2 years if there is continued exposure to Salmonella typhi.
Usual Pediatric Dose for Typhoid Prophylaxis:
>2 years:
0.5 mL IM once in the deltoid or the vastus lateralis. Do not inject into the gluteal area where there may be a nerve trunk.
The vaccine should be given at least 2 weeks before potential exposure to S typhi.
Booster: 0.5 mL IM every 2 years if there is continued exposure to Salmonella typhi.
What other drugs will affect typhoid vaccine?
Before receiving this vaccine, tell the doctor about all other vaccines you have recently received.
Also tell the doctor about all medications you use, especially a blood thinner such as warfarin (Coumadin).
There may be other drugs that can affect this vaccine. Tell your doctor about all the prescription and over-the-counter medications you have received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your doctor or pharmacist may have information about this vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:39:10 PM.
Typhim VI
30/06/10
Generic Name: typhoid vaccine (inactivated), injection (TYE foid vax EEN)
Brand Names: Typhim VI
What is typhoid vaccine?
Typhoid (also called “typhoid fever”) is a serious disease caused by Salmonella typhi bacteria. Typhoid can be fatal if left untreated.
Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.
Untreated typhoid infection may lead to kidney failure, or intestinal bleeding caused by perforation (forming of a hole), which can be fatal. If the infection spreads to the gallbladder, the infected person may become a chronic carrier of the bacteria that causes typhoid. A carrier may have no symptoms but is capable of spreading the infection to others.
Typhoid is spread through contact with the stool (bowel movements) of a person infected with the bacteria. This usually occurs by eating food or drinking water that has become contaminated with feces from an infected person. Once in the digestive tract, typhoid infection can spread to the blood and other parts of the body.
Typhoid fever is most common in non-industrialized parts of the world, especially Asia, Africa, and Central or South America. People who travel to those regions are at risk of coming into contact with the disease.
The typhoid vaccine is used to help prevent this disease in adults and children who are at least 2 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for people who travel to areas where the disease is common.
This vaccine works by exposing you to a small dose of an extract from the bacteria, which causes your body to develop immunity to the disease.
Typhoid vaccine will not treat an active infection that has already developed in the body, and will not prevent any disease caused by bacteria other than Salmonella typhi.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
What is the most important information I should know about typhoid vaccine?
You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past. Typhoid vaccine should not be used in a person who is a typhoid carrier.
Before you receive this vaccine, tell the doctor if you have a bleeding or blood clotting disorder (such as hemophilia), a weak immune system caused by disease or by taking certain medicines, or if you are taking a blood thinner or receiving cancer treatments or radiation.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
In addition to receiving typhoid vaccine, take precautions while traveling such as avoiding raw fruits or vegetables that cannot be peeled, drinks that contain ice, flavored ices that may have been made with contaminated water, unbottled or unboiled water, or any food or beverage purchased from a street vendor.
Keep track of any and all side effects you have after receiving a typhoid vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
What should I discuss with my healthcare provider before receiving typhoid vaccine?
Typhoid vaccine should not be used in a person who is a typhoid carrier. You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past.
Typhoid vaccine may not work as well in someone who has a weak immune system caused by disease or by taking certain medicines or receiving cancer treatments, including radiation.
Before you receive this vaccine, tell the doctor if you have a bleeding or blood clotting disorder such as hemophilia or easy bruising.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, the doctor may ask you to wait until you get better before you can receive the vaccine.
Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with typhoid. It is not known whether typhoid vaccine passes into breast milk, or if it could harm a nursing baby. Do not receive this vaccine without telling your doctor if you are breast-feeding a baby.
How is typhoid vaccine given?
This vaccine is given as an injection (shot) into a muscle. You will receive this injection in a doctor’s office or other clinic setting.
The typhoid vaccine is given as a single injection. A booster dose is then recommended every 2 years during possible exposure to typhoid. Your individual booster schedule may be different from these guidelines. Follow your doctor’s instructions or the schedule recommended by the Centers for Disease Control and Prevention (CDC).
If you are being vaccinated before traveling, you should receive the typhoid vaccine at least 2 weeks before your scheduled departure.
Typhoid vaccine is recommended for adults and children in the following situations:
-
people who travel to countries where typhoid fever is common;
-
people who will have long-term exposure to food or water that may be contaminated with typhoid;
-
people who live with someone who is a typhoid carrier; and
-
laboratory workers who may come into contact with Salmonella typhi in a work setting.
Wash your hands often to help prevent typhoid when you are in an area where contamination is possible.
What happens if I miss a dose?
Contact your doctor if you will miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.
Be sure to receive a booster dose of this vaccine every 2 years during continued exposure to typhoid. If you do not receive the booster every 2 years, you may not be fully protected against the disease.
What happens if I overdose?
An overdose of this vaccine is unlikely to occur.
What should I avoid before or after getting typhoid vaccine?
In addition to receiving typhoid vaccine, take precautions while traveling to further prevent coming into contact with bacteria that cause typhoid fever:
-
Avoid eating leafy vegetables such as spinach or lettuce, which are harder to wash properly.
-
Avoid eating raw fruits or vegetables that cannot be peeled, or that have been peeled by another person.
-
Avoid drinks that contain ice, or frozen treats and flavored ices that may have been made with contaminated water.
-
Avoid eating foods you have not cooked or prepared yourself. Use clean surfaces and utensils when preparing food.
-
Drink only bottled water (carbonated is best) or water that has been boiled for at least 1 minute.
-
Avoid any food or beverage purchased from a street vendor.
Typhoid vaccine side effects
You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot. Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with typhoid is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
-
fever, swollen glands, rash or itching, joint pain, or general ill feeling;
-
tremors or shaking; or
-
feeling like you might pass out.
Less serious side effects include:
-
pain, tenderness, redness, swelling, or a hard lump where the shot was given;
-
low fever;
-
headache;
-
muscle or joint pain;
-
nausea, diarrhea, stomach pain; or
-
weakness.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect typhoid vaccine?
Before receiving this vaccine, tell the doctor about all other vaccines you have recently received.
Also tell the doctor about all medications you use, especially a blood thinner such as warfarin (Coumadin).
There may be other drugs that can affect this vaccine. Tell your doctor about all the prescription and over-the-counter medications you have received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your doctor or pharmacist may have information about this vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision Date: 4/12/2009 4:39:10 PM.
Tympagesic
30/06/10
Generic Name: Antipyrine/Benzocaine/Phenylephrine (an-tee-PYE-reen/BEN-zoe-kane/fen-ill-EF-rin)
Brand Name: Examples include Otogesic and Tympagesic
Tympagesic is used for:
Relieving pain in the ear caused by various conditions. It may be used with antibiotics given by mouth to treat middle ear infections.
Tympagesic is an analgesic, anesthetic, and sympathomimetic combination. It works by relieving pressure and reducing inflammation, congestion, pain, and discomfort.
Do NOT use Tympagesic if:
- you are allergic to any ingredient in Tympagesic or to similar medicines
- your eardrum is perforated or you have discharge from your ear
Contact your doctor or health care provider right away if any of these apply to you.
Before using Tympagesic:
Some medical conditions may interact with Tympagesic. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are allergic to other local anesthetics (eg, lidocaine)
- if you have asthma, high blood pressure, glaucoma or increased eye pressure, diabetes, heart problems (eg, ischemic heart disease), an enlarged prostate, or an overactive thyroid
Some MEDICINES MAY INTERACT with Tympagesic. However, no specific interactions with Tympagesic are known at this time.
Ask your health care provider if Tympagesic may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Tympagesic:
Use Tympagesic as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- For topical use in the ear canal only. Do not get Tympagesic in the eyes, nose, or mouth. If you get Tympagesic in your eyes, rinse thoroughly with cool water.
- To use ear drops, lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for several minutes so the medicine can run to the bottom of the ear canal. Moisten a clean cotton plug with Tympagesic and gently insert into the ear canal to prevent medicine from leaking out.
- To prevent germs from contaminating the medicine, do not touch the applicator to any surface, including the ear. Do not rinse dropper after use. Keep the container tightly closed.
- If you miss a dose of Tympagesic, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Tympagesic.
Important safety information:
- Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.
- Tympagesic may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
- Use Tympagesic with caution in the ELDERLY; they may be more sensitive to its effects
- Tympagesic should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tympagesic while you are pregnant. It is not known if Tympagesic is found in breast milk. If you are or will be breast-feeding while you use Tympagesic, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Tympagesic:
All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation not present when you began using Tympagesic; redness, itching, blistering, or oozing at the application site.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include anxiety; dizziness; headache; nausea; nervousness; ringing in the ears; sweating; unusually pale or cool skin; vomiting.
Proper storage of Tympagesic:
Store Tympagesic at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Protect from freezing. Keep the container tightly closed. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tympagesic out of the reach of children and away from pets.
General information:
- If you have any questions about Tympagesic, please talk with your doctor, pharmacist, or other health care provider.
- Tympagesic is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Tympagesic. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Tylenol with Codeine No. 3
30/06/10
Generic Name: acetaminophen and codeine (Oral route)
a-seet-a-MIN-oh-fen, KOE-deen FOS-fate
Commonly used brand name(s):
In the U.S.
- APAP w/Codeine
- Capital w/Codeine
- Pyregesic-C
- Tylenol w/Codeine
- Tylenol w/Codeine #3
- Tylenol w/Codeine #4
- Tylenol with Codeine No. 3
- Vopac
Available Dosage Forms:
- Tablet
- Capsule
- Elixir
- Suspension
- Solution
Therapeutic Class: Opioid/Acetaminophen Combination
Chemical Class: Codeine
Uses For Tylenol with Codeine No. 3
Acetaminophen and codeine oral suspension is used to relieve mild to moderate pain. The oral tablets are used to relieve mild to moderately severe pain.
Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.
Codeine belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.
When codeine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.
This medicine is available only with your doctor’s prescription.
Before Using Tylenol with Codeine No. 3
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of acetaminophen and codeine oral suspension in children younger than 3 years of age. Safety and efficacy have not been established.
No information is available on the relationship of age to the effects of acetaminophen and codeine tablets in the pediatric population. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of acetaminophen and codeine combination in geriatric patients.
Pregnancy
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | C | Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. |
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Naltrexone
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Adinazolam
- Alfentanil
- Alprazolam
- Amobarbital
- Anileridine
- Aprobarbital
- Bromazepam
- Brotizolam
- Buprenorphine
- Butabarbital
- Butalbital
- Butorphanol
- Carisoprodol
- Chloral Hydrate
- Chlordiazepoxide
- Chlorzoxazone
- Clobazam
- Clonazepam
- Clorazepate
- Codeine
- Dantrolene
- Dezocine
- Diazepam
- Estazolam
- Ethchlorvynol
- Fentanyl
- Flunitrazepam
- Flurazepam
- Halazepam
- Hydrocodone
- Hydromorphone
- Ketazolam
- Levorphanol
- Lorazepam
- Lormetazepam
- Medazepam
- Meperidine
- Mephenesin
- Mephobarbital
- Meprobamate
- Metaxalone
- Methocarbamol
- Methohexital
- Midazolam
- Morphine
- Morphine Sulfate Liposome
- Nalbuphine
- Nitrazepam
- Nordazepam
- Opium
- Oxazepam
- Oxycodone
- Oxymorphone
- Pentazocine
- Pentobarbital
- Phenobarbital
- Prazepam
- Propoxyphene
- Quazepam
- Remifentanil
- Secobarbital
- Sodium Oxybate
- Sufentanil
- Tapentadol
- Temazepam
- Thiopental
- Triazolam
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acenocoumarol
- Carbamazepine
- Isoniazid
- Phenytoin
- Warfarin
- Zidovudine
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Ethanol
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
- Cabbage
- Ethanol
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Addison’s disease (adrenal gland problem) or
- Alcohol abuse, history of or
- Breathing problems (e.g., chronic obstructive pulmonary disease [COPD], cor pulmonale, hypoxia) or
- CNS depression or
- Drug dependence, especially narcotic abuse or dependence, or history of or
- Enlarged prostate (BPH, prostatic hypertrophy) or
- Hypothyroidism (an underactive thyroid) or
- Problems with passing urine—Use with caution. May increase risk for more serious side effects.
- Brain tumor or
- Head injuries or
- Increased pressure in the head—Some of the side effects of codeine can cause serious problems in people who have these medical problems.
- Kidney disease or
- Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
- Respiratory depression (hypoventilation or slow breathing)—Use with caution. May make this conditions worse.
- Stomach or digestion problems—This medicine may mask the diagnosis of these conditions.
Proper Use of acetaminophen and codeine
This section provides information on the proper use of a number of products that contain acetaminophen and codeine. It may not be specific to Tylenol with Codeine No. 3. Please read with care.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose. Large amounts of acetaminophen may cause liver damage.
Shake the oral suspension well before each use. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.
This combination medicine contains acetaminophen (Tylenol®). Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours).
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (suspension):
- For mild to moderate pain:
- Adults—15 milliliters (mL) or 1 tablespoonful every 4 hours as needed.
- Children 7 to 12 years of age—10 mL (2 teaspoonfuls) 3 or 4 times per day.
- Children 3 to 6 years of age—5 mL (1 teaspoonful) 3 or 4 times per day.
- Children younger than 3 years of age—Use and dose must be determined by your doctor.
- For mild to moderate pain:
- For oral dosage form (tablets):
- For mild to moderately severe pain:
- Adults—15 to 60 milligrams (mg) of codeine and 300 to 1000 mg of acetaminophen every 4 hours as needed. Your doctor may increase your dose as needed. However, the dose is usually not more than 360 mg of codeine and 4000 mg of acetaminophen per 24 hours.
- Children—Use and dose must be determined by your doctor.
- For mild to moderately severe pain:
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions While Using Tylenol with Codeine No. 3
It is very important that your doctor check the progress of you or your child while you are taking this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you or your child should continue to take it.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Also, there may be a greater risk of liver damage if you drink three or more alcoholic beverages while you are taking acetaminophen. Do not drink alcoholic beverages, and check with your doctor before taking any of these medicines while you are using this medicine.
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose.
This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
For patients taking a codeine-containing medicine or any other narcotic analgesics (e.g., dihydrocodeine, hydrocodone, oxycodone, and pentazocine):
- Contact your doctor right away if you have extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an “ultra-rapid metabolizer of codeine”. Ultra-rapid metabolizers change codeine to morphine more quickly and completely than other people. As a result, there is too much morphine in the body and more side effects of morphine than usual.
Do not change your dose or suddenly stop using this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.
Using this medicine while you are pregnant may cause neonatal withdrawal syndrome in your newborn babies. Tell your doctor right away if your child has the following symptoms: abnormal sleep pattern, diarrhea, high-pitched cry, irritability, shakiness or tremor, weight loss, vomiting, or failure to gain weight.
Before you have any medical tests, tell the medical doctor in charge that you or your child are taking this medicine. The results of certain tests may be affected by this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Tylenol with Codeine No. 3 Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Difficult or troubled breathing
- irregular, fast or slow, or shallow breathing
- pale or blue lips, fingernails, or skin
- shortness of breath
Incidence not known
- Black, tarry stools
- bleeding gums
- blood in the urine or stools
- cough or hoarseness
- difficulty with swallowing
- dizziness
- fast heartbeat
- fever with or without chills
- general feeling of tiredness or weakness
- hives
- itching
- lower back or side pain
- painful or difficult urination
- pinpoint red spots on the skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- skin rash
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- tightness in the chest
- unusual bleeding or bruising
- unusual tiredness or weakness
- wheezing
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Abdominal or stomach pain
- bloody or cloudy urine
- chills
- constricted, pinpoint, or small pupils (black part of the eye)
- convulsion
- dark urine
- headache
- increased sweating
- light-colored stools
- loss of appetite
- loss of consciousness
- nausea
- sudden decrease in the amount of urine
- unpleasant breath odor
- vomiting
- vomiting of blood
- yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Drowsiness
- lightheadedness
- relaxed and calm
- sleepiness
Incidence not known
- Difficulty having a bowel movement (stool)
- false or unusual sense of well-being
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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