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Veramyst Spray

30/06/10

Generic Name: Fluticasone Furoate (floo-TIK-a-sone)
Brand Name: Veramyst

Veramyst Spray is used for:

Treatment of allergic and nonallergic nasal symptoms including congestion, sneezing, itching, and runny nose.

Veramyst Spray is a corticosteroid. It works by reducing inflammatory reactions in the nasal airway in response to allergens and irritants in the air.

Do NOT use Veramyst Spray if:

you are allergic to any ingredient in Veramyst Spray
you have recently had an ulcer in your nose, nasal surgery, or a nasal injury
you are taking certain HIV protease inhibitors (eg, ritonavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Veramyst Spray:

Some medical conditions may interact with Veramyst Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have active or inactive tuberculosis or a positive skin test for tuberculosis
if you have infections of the respiratory tract, untreated fungal or bacterial infections, parasitic or viral infections, measles, chickenpox, or herpes simplex in or around the eye, or you have recently received a vaccination
if you have diarrhea or a history of severe liver problems, asthma, glaucoma, or cataracts
if you have a medical condition requiring long-term use of corticosteroids (eg, prednisone)

Some MEDICINES MAY INTERACT with Veramyst Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

Azole antifungals (eg, ketoconazole), certain HIV protease inhibitors (eg, ritonavir), or delavirdine because they may increase the risk of Veramyst Spray’s side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Veramyst Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Veramyst Spray:

Use Veramyst Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Veramyst Spray. Talk to your pharmacist if you have questions about this information.
You will need to prime Veramyst Spray before you use it for the first time. To prime Veramyst Spray, shake it well then spray 6 test sprays in to the air away from your face. You will need to re-prime the medicine if it is not used for 30 days or longer or if the cap is left off the bottle for 5 days or longer
Shake Veramyst Spray well before each use.
To use Veramyst Spray, gently blow your nose. Remove the cap and hold the spray device upright. Tilt your head forward slightly and place the nozzle in one nostril. Point the end of the nozzle toward the side of your nose (away from the center of your nose). Firmly press the mist release button while breathing in gently through your nose, then remove the nozzle from your nose and breathe out through your mouth. Repeat these steps for the other nostril. After you finish your dose, wipe the nozzle with a clean, dry tissue and replace the cap.
Clean the inside of the cap once a week with a clean, dry tissue. Never try to clean the nozzle with a pin or anything sharp; doing so may damage the nozzle.
Use Veramyst Spray on a regular schedule to get the most benefit from it. Using Veramyst Spray at the same time each day will help you remember to use it.
Symptoms may begin to improve within 24 hours after you start Veramyst Spray. However, it may take several days before you notice the full benefit of Veramyst Spray. If symptoms do not improve or if the condition worsens, contact your health care provider. Continue to use Veramyst Spray even if you feel well. Do not miss any doses.
If you miss a dose of Veramyst Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Veramyst Spray.

Important safety information:

Use caution if you switch from an oral steroid (eg, prednisone) to Veramyst Spray. It may take several months for your body to make enough natural steroids to handle events that cause physical stress. Such events may include injury, surgery, infection, loss of blood electrolytes, or a sudden asthma attack. These may be severe and sometimes fatal. Contact your doctor right away if any of these events occur. You may need to take an oral steroid (eg, prednisone) again. Carry a card at all times that says you may need an oral steroid (eg, prednisone) if any of these events occur.
Tell your doctor or dentist that you take Veramyst Spray before you receive any medical or dental care, emergency care, or surgery.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
If you have NOT had chickenpox or measles, avoid contact with anyone who does. Contact your doctor right away if you are exposed to anyone with these conditions.
Avoid spraying in the eyes.
Veramyst Spray should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Veramyst Spray.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Veramyst Spray while you are pregnant. It is not known if Veramyst Spray is found in breast milk. If you are or will be breast-feeding while you use Veramyst Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Veramyst Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; cough; headache; minor nosebleed; sore throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; severe or persistent nosebleed; severe or persistent pain in the nose or throat; slow wound healing; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Veramyst Spray:

Store Veramyst Spray between 39 and 86 degrees F (4 and 30 degrees C). Store in the upright position with the cap in place. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Veramyst Spray out of the reach of children and away from pets.

General information:

If you have any questions about Veramyst Spray, please talk with your doctor, pharmacist, or other health care provider.
Veramyst Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Veramyst Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

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Ventolin Rotacaps

30/06/10

Generic Name: albuterol (Inhalation route)

al-BUE-ter-ol

Commonly used brand name(s):

In the U.S.

Accuneb
ProAir HFA
Proventil
Proventil HFA
ReliOn Ventolin HFA
Ventolin
Ventolin HFA

In Canada

Alti-Salbutamol Inhalation Aerosol
Apo-Salvent
Salbutamol
Salbutamol Nebuamp
Salbutamol Respirator Solution
Ventolin Inhaler
Ventolin Nebules P.F.
Ventolin Respirator
Ventolin Rotacaps

Available Dosage Forms:

Aerosol Powder
Solution
Capsule
Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin Rotacaps

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent exercise-induced bronchospasm.

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor’s prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, albuterol is used in certain patients with the following medical condition:

Hyperkalemia (too much potassium in the blood)

Before Using Ventolin Rotacaps

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of albuterol inhalation aerosol (e.g., Proair(R) HFA) in children 4 years of age and older and albuterol inhalation solution (e.g., Accuneb(R)) in children 2 years of age and older.

Geriatric

No information is available on the relationship of age to the effects of albuterol inhalation solution (e.g., Accuneb(R)) in geriatric patients.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of albuterol inhalation aerosol (e.g., Proair(R) HFA) in geriatric patients. However, elderly patients are more likely to have age-related heart or kidney problems, which may require caution and an adjustment in the dose for patients receiving albuterol.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acebutolol
Alprenolol
Arotinolol
Atenolol
Atomoxetine
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Carteolol
Carvedilol
Celiprolol
Clorgyline
Dilevalol
Esmolol
Furazolidone
Iproniazid
Isocarboxazid
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Selegiline
Sotalol
Talinolol
Tertatolol
Timolol
Toloxatone
Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin Rotacaps. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop taking this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (e.g., Accuneb(R)) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose.
Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine.
Connect the nebulizer to the face mask or mouthpiece.
Use the face mask or mouthpiece to breathe in the medicine.
Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.
Clean all the parts of the nebulizer after each use.

The inhalation aerosol (e.g., Proair(R) HFA) is used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check you or your child on a regular basis to make sure you are using it properly.

To use the inhaler:

The inhaler should be at room temperature before you use it.
Insert the metal canister firmly and fully into the clear end of the Proair(R) HFA mouthpiece. This mouthpiece should not be used with other inhaled medicines.
Remove the cap and look at the mouthpiece to make sure it is clean.
Shake the inhaler well and test spray it in the air 3 times before using it for the first time or if the inhaler has not been used for more than 2 weeks.
To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.
Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.
Hold your breath for about 10 seconds, then breathe out slowly.
If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.
When you have finished all of your doses, rinse your mouth with water and spit the water out.
Clean the inhaler mouthpiece every day with warm running water for 30 seconds. Dry it thoroughly before use.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For prevention of bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.
- For inhalation solution dosage form (used with a nebulizer):
  - Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.
  - Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.
  - Children younger than 2 years of age—Use and dose must be determined by your child’s doctor.
For prevention of exercise-induced bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin Rotacaps

It is very important that your doctor check your progress or your child’s progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for any unwanted effects.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Check with your doctor right away if you or your child have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

You or your child may also be taking an antiinflammatory medicine, such as a steroid, together with this medicine. Do not stop taking the antiinflammatory medicine, even if your asthma seems better, unless you are told to do so by your doctor.

Albuterol may cause allergic reactions. Stop using the medicine and check with your doctor right away if you or your child develop a skin rash, hives, itching, swelling, or any type of allergic reaction after taking this medicine.

Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you or your child have more than one of the following symptoms: convulsions; decreased urine; dry mouth; increased thirst; irregular heartbeat; loss of appetite; mood changes; muscle pain or cramps; nausea or vomiting; numbness or tingling in the hands, feet, or lips; shortness of breath; or unusual tiredness or weakness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

Ventolin Rotacaps Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fast, irregular, pounding, or racing heartbeat or pulse
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet

Less common

Abdominal or stomach pain
bladder pain
bloody or cloudy urine
chest discomfort
chest pain
cough or hoarseness
cough producing mucus
diarrhea
difficult or labored breathing
difficulty with swallowing
dizziness
feeling of warmth
fever or chills
frequent urge to urinate
hives
itching
loss of appetite
lower back or side pain
nausea
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the face, neck, arms, and occasionally, upper chest
runny nose
shortness of breath
skin rash
sore throat
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
unusual tiredness or weakness
weakness
wheezing

Rare

Hives or welts
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
redness of the skin
swelling of the mouth or throat
trouble breathing

Incidence not known

Agitation
anxiety
arm, back, or jaw pain
chest tightness or heaviness
confusion
convulsions
decreased urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
dry mouth
extra heartbeats
fainting
flushed, dry skin
fruit-like breath odor
hallucinations
headache
increased hunger
increased thirst
increased urination
irritability
lightheadedness
muscle pain or cramps
nervousness
nightmares
numbness or tingling in the hands, feet, or lips
pounding in the ears
rapid, deep breathing
restlessness
shakiness
slow or fast heartbeat
stomach cramps
sweating
unexplained weight loss
unusual feeling of excitement
vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain
congestion
fever
runny nose
tender, swollen glands in the neck
trouble with swallowing
voice changes

Less common

Difficult, burning, or painful urination
earache
headache, severe and throbbing
muscle or bone pain
pain
redness of the skin
redness or swelling in the ear
redness, swelling, or soreness of the tongue
sleeplessness
sneezing
stuffy nose
swelling
tenderness
trouble in holding or releasing urine
trouble sleeping
unable to sleep
warmth on the skin

Rare

Sleepiness or unusual drowsiness

Incidence not known

Bad, unusual, or unpleasant (after) taste
change in taste
feeling of constant movement of self or surroundings
gagging
rough, scratchy sound to voice
sensation of spinning
tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided “AS IS” and “as available” for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

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VePesid

30/06/10

Generic Name: etoposide (oral) (ee TOW poh side)
Brand Names: VePesid

What is etoposide?

Etoposide is a cancer medicine that interferes with the growth of cancer cells and slows their growth and spread in the body.

Etoposide is used to treat cancer of the lung or testicles.

Etoposide may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about etoposide?

Do not use this medication without your doctor’s consent if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Do not break or open an etoposide capsule. The medicine from a broken capsule can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If skin contact occurs, wash the area with soap and water or rinse the eyes thoroughly with plain water. If you must handle a broken capsule, ask your doctor or pharmacist how to safely dispose of the capsule.

Etoposide can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.

Using etoposide may increase your risk of developing other types of cancer, such as leukemia. Talk with your doctor about your specific risk.

What should I discuss with my healthcare provider before taking etoposide?

Before using etoposide, tell your doctor if you have:

kidney disease; or
a weak immune system (from disease or from taking certain medicines).

If you have any of these conditions, you may not be able to use etoposide, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use etoposide without your doctor’s consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. It is not known whether etoposide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Using etoposide may increase your risk of developing other types of cancer, such as leukemia. Talk with your doctor about your specific risk.

How should I use etoposide?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Take each dose with a full glass of water. Do not break or open an etoposide capsule. The medicine from a broken capsule can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If skin contact occurs, wash the area with soap and water or rinse the eyes thoroughly with plain water. If you must handle a broken capsule, ask your doctor or pharmacist how to safely dispose of the capsule.

Store etoposide capsules in the refrigerator. Do not allow them to freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an etoposide overdose may include severe nausea and vomiting, fever, chills, sore throat, flu symptoms, easy bruising, or extreme weakness.

What should I avoid while using etoposide?

Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.

Do not receive a “live” vaccine while you are being treated with etoposide.

Etoposide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

fever, chills, body aches, flu symptoms;
white patches or sores inside your mouth or on your lips;
easy bruising or bleeding, unusual weakness;
fast heart rate;
severe nausea and vomiting;
feeling light-headed, fainting; or
low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Other, less serious side effects may be more likely to occur, such as:

mild nausea, vomiting, stomach pain;
mild itching or skin rash; or
temporary hair loss.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect etoposide?

Before using etoposide, tell your doctor if you are using cyclosporine (Neoral, Sandimmune, Gengraf).

There may be other drugs that can affect etoposide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has more information about etoposide written for health professionals that you may read.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Ventolin Inhaler

30/06/10

Generic Name: albuterol (Inhalation route)

al-BUE-ter-ol

Commonly used brand name(s):

In the U.S.

Accuneb
ProAir HFA
Proventil
Proventil HFA
ReliOn Ventolin HFA
Ventolin
Ventolin HFA

In Canada

Alti-Salbutamol Inhalation Aerosol
Apo-Salvent
Salbutamol
Salbutamol Nebuamp
Salbutamol Respirator Solution
Ventolin Inhaler
Ventolin Nebules P.F.
Ventolin Respirator
Ventolin Rotacaps

Available Dosage Forms:

Aerosol Powder
Solution
Capsule
Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin Inhaler

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent exercise-induced bronchospasm.

This medicine is available only with your doctor’s prescription.

Hyperkalemia (too much potassium in the blood)

Before Using Ventolin Inhaler

Allergies

Pediatric

Geriatric

No information is available on the relationship of age to the effects of albuterol inhalation solution (e.g., Accuneb(R)) in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Acebutolol
Alprenolol
Arotinolol
Atenolol
Atomoxetine
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Carteolol
Carvedilol
Celiprolol
Clorgyline
Dilevalol
Esmolol
Furazolidone
Iproniazid
Isocarboxazid
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Selegiline
Sotalol
Talinolol
Tertatolol
Timolol
Toloxatone
Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin Inhaler. Please read with care.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose.
Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine.
Connect the nebulizer to the face mask or mouthpiece.
Use the face mask or mouthpiece to breathe in the medicine.
Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.
Clean all the parts of the nebulizer after each use.

To use the inhaler:

The inhaler should be at room temperature before you use it.
Insert the metal canister firmly and fully into the clear end of the Proair(R) HFA mouthpiece. This mouthpiece should not be used with other inhaled medicines.
Remove the cap and look at the mouthpiece to make sure it is clean.
Shake the inhaler well and test spray it in the air 3 times before using it for the first time or if the inhaler has not been used for more than 2 weeks.
To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.
Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.
Hold your breath for about 10 seconds, then breathe out slowly.
If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.
When you have finished all of your doses, rinse your mouth with water and spit the water out.
Clean the inhaler mouthpiece every day with warm running water for 30 seconds. Dry it thoroughly before use.

Dosing

For prevention of bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.
- For inhalation solution dosage form (used with a nebulizer):
  - Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.
  - Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.
  - Children younger than 2 years of age—Use and dose must be determined by your child’s doctor.
For prevention of exercise-induced bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.

Missed Dose

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin Inhaler

Ventolin Inhaler Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fast, irregular, pounding, or racing heartbeat or pulse
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet

Less common

Abdominal or stomach pain
bladder pain
bloody or cloudy urine
chest discomfort
chest pain
cough or hoarseness
cough producing mucus
diarrhea
difficult or labored breathing
difficulty with swallowing
dizziness
feeling of warmth
fever or chills
frequent urge to urinate
hives
itching
loss of appetite
lower back or side pain
nausea
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the face, neck, arms, and occasionally, upper chest
runny nose
shortness of breath
skin rash
sore throat
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
unusual tiredness or weakness
weakness
wheezing

Rare

Hives or welts
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
redness of the skin
swelling of the mouth or throat
trouble breathing

Incidence not known

Agitation
anxiety
arm, back, or jaw pain
chest tightness or heaviness
confusion
convulsions
decreased urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
dry mouth
extra heartbeats
fainting
flushed, dry skin
fruit-like breath odor
hallucinations
headache
increased hunger
increased thirst
increased urination
irritability
lightheadedness
muscle pain or cramps
nervousness
nightmares
numbness or tingling in the hands, feet, or lips
pounding in the ears
rapid, deep breathing
restlessness
shakiness
slow or fast heartbeat
stomach cramps
sweating
unexplained weight loss
unusual feeling of excitement
vomiting

More common

Body aches or pain
congestion
fever
runny nose
tender, swollen glands in the neck
trouble with swallowing
voice changes

Less common

Difficult, burning, or painful urination
earache
headache, severe and throbbing
muscle or bone pain
pain
redness of the skin
redness or swelling in the ear
redness, swelling, or soreness of the tongue
sleeplessness
sneezing
stuffy nose
swelling
tenderness
trouble in holding or releasing urine
trouble sleeping
unable to sleep
warmth on the skin

Rare

Sleepiness or unusual drowsiness

Incidence not known

Bad, unusual, or unpleasant (after) taste
change in taste
feeling of constant movement of self or surroundings
gagging
rough, scratchy sound to voice
sensation of spinning
tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Ventolin Nebules P.F.

30/06/10

Generic Name: albuterol (Inhalation route)

al-BUE-ter-ol

Commonly used brand name(s):

In the U.S.

Accuneb
ProAir HFA
Proventil
Proventil HFA
ReliOn Ventolin HFA
Ventolin
Ventolin HFA

In Canada

Alti-Salbutamol Inhalation Aerosol
Apo-Salvent
Salbutamol
Salbutamol Nebuamp
Salbutamol Respirator Solution
Ventolin Inhaler
Ventolin Nebules P.F.
Ventolin Respirator
Ventolin Rotacaps

Available Dosage Forms:

Aerosol Powder
Solution
Capsule
Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin Nebules P.F.

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent exercise-induced bronchospasm.

This medicine is available only with your doctor’s prescription.

Hyperkalemia (too much potassium in the blood)

Before Using Ventolin Nebules P.F.

Allergies

Pediatric

Geriatric

No information is available on the relationship of age to the effects of albuterol inhalation solution (e.g., Accuneb(R)) in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Acebutolol
Alprenolol
Arotinolol
Atenolol
Atomoxetine
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Carteolol
Carvedilol
Celiprolol
Clorgyline
Dilevalol
Esmolol
Furazolidone
Iproniazid
Isocarboxazid
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Selegiline
Sotalol
Talinolol
Tertatolol
Timolol
Toloxatone
Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin Nebules P.F.. Please read with care.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose.
Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine.
Connect the nebulizer to the face mask or mouthpiece.
Use the face mask or mouthpiece to breathe in the medicine.
Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.
Clean all the parts of the nebulizer after each use.

To use the inhaler:

The inhaler should be at room temperature before you use it.
Insert the metal canister firmly and fully into the clear end of the Proair(R) HFA mouthpiece. This mouthpiece should not be used with other inhaled medicines.
Remove the cap and look at the mouthpiece to make sure it is clean.
Shake the inhaler well and test spray it in the air 3 times before using it for the first time or if the inhaler has not been used for more than 2 weeks.
To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.
Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.
Hold your breath for about 10 seconds, then breathe out slowly.
If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.
When you have finished all of your doses, rinse your mouth with water and spit the water out.
Clean the inhaler mouthpiece every day with warm running water for 30 seconds. Dry it thoroughly before use.

Dosing

For prevention of bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.
- For inhalation solution dosage form (used with a nebulizer):
  - Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.
  - Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.
  - Children younger than 2 years of age—Use and dose must be determined by your child’s doctor.
For prevention of exercise-induced bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.

Missed Dose

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin Nebules P.F.

Ventolin Nebules P.F. Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fast, irregular, pounding, or racing heartbeat or pulse
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet

Less common

Abdominal or stomach pain
bladder pain
bloody or cloudy urine
chest discomfort
chest pain
cough or hoarseness
cough producing mucus
diarrhea
difficult or labored breathing
difficulty with swallowing
dizziness
feeling of warmth
fever or chills
frequent urge to urinate
hives
itching
loss of appetite
lower back or side pain
nausea
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the face, neck, arms, and occasionally, upper chest
runny nose
shortness of breath
skin rash
sore throat
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
unusual tiredness or weakness
weakness
wheezing

Rare

Hives or welts
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
redness of the skin
swelling of the mouth or throat
trouble breathing

Incidence not known

Agitation
anxiety
arm, back, or jaw pain
chest tightness or heaviness
confusion
convulsions
decreased urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
dry mouth
extra heartbeats
fainting
flushed, dry skin
fruit-like breath odor
hallucinations
headache
increased hunger
increased thirst
increased urination
irritability
lightheadedness
muscle pain or cramps
nervousness
nightmares
numbness or tingling in the hands, feet, or lips
pounding in the ears
rapid, deep breathing
restlessness
shakiness
slow or fast heartbeat
stomach cramps
sweating
unexplained weight loss
unusual feeling of excitement
vomiting

More common

Body aches or pain
congestion
fever
runny nose
tender, swollen glands in the neck
trouble with swallowing
voice changes

Less common

Difficult, burning, or painful urination
earache
headache, severe and throbbing
muscle or bone pain
pain
redness of the skin
redness or swelling in the ear
redness, swelling, or soreness of the tongue
sleeplessness
sneezing
stuffy nose
swelling
tenderness
trouble in holding or releasing urine
trouble sleeping
unable to sleep
warmth on the skin

Rare

Sleepiness or unusual drowsiness

Incidence not known

Bad, unusual, or unpleasant (after) taste
change in taste
feeling of constant movement of self or surroundings
gagging
rough, scratchy sound to voice
sensation of spinning
tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Comments (0)

Ventolin Respirator

30/06/10

Generic Name: albuterol (Inhalation route)

al-BUE-ter-ol

Commonly used brand name(s):

In the U.S.

Accuneb
ProAir HFA
Proventil
Proventil HFA
ReliOn Ventolin HFA
Ventolin
Ventolin HFA

In Canada

Alti-Salbutamol Inhalation Aerosol
Apo-Salvent
Salbutamol
Salbutamol Nebuamp
Salbutamol Respirator Solution
Ventolin Inhaler
Ventolin Nebules P.F.
Ventolin Respirator
Ventolin Rotacaps

Available Dosage Forms:

Aerosol Powder
Solution
Capsule
Powder

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin Respirator

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent exercise-induced bronchospasm.

This medicine is available only with your doctor’s prescription.

Hyperkalemia (too much potassium in the blood)

Before Using Ventolin Respirator

Allergies

Pediatric

Geriatric

No information is available on the relationship of age to the effects of albuterol inhalation solution (e.g., Accuneb(R)) in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Acebutolol
Alprenolol
Arotinolol
Atenolol
Atomoxetine
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Carteolol
Carvedilol
Celiprolol
Clorgyline
Dilevalol
Esmolol
Furazolidone
Iproniazid
Isocarboxazid
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Selegiline
Sotalol
Talinolol
Tertatolol
Timolol
Toloxatone
Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin Respirator. Please read with care.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose.
Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine.
Connect the nebulizer to the face mask or mouthpiece.
Use the face mask or mouthpiece to breathe in the medicine.
Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone.
Clean all the parts of the nebulizer after each use.

To use the inhaler:

The inhaler should be at room temperature before you use it.
Insert the metal canister firmly and fully into the clear end of the Proair(R) HFA mouthpiece. This mouthpiece should not be used with other inhaled medicines.
Remove the cap and look at the mouthpiece to make sure it is clean.
Shake the inhaler well and test spray it in the air 3 times before using it for the first time or if the inhaler has not been used for more than 2 weeks.
To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright.
Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister.
Hold your breath for about 10 seconds, then breathe out slowly.
If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler.
When you have finished all of your doses, rinse your mouth with water and spit the water out.
Clean the inhaler mouthpiece every day with warm running water for 30 seconds. Dry it thoroughly before use.

Dosing

For prevention of bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs every 4 to 6 hours as needed.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.
- For inhalation solution dosage form (used with a nebulizer):
  - Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed.
  - Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed.
  - Children younger than 2 years of age—Use and dose must be determined by your child’s doctor.
For prevention of exercise-induced bronchospasm:
- For inhalation aerosol dosage form (inhaler):
  - Adults, teenagers, and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise.
  - Children younger than 4 years of age—Use and dose must be determined by your child’s doctor.

Missed Dose

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin Respirator

Ventolin Respirator Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fast, irregular, pounding, or racing heartbeat or pulse
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet

Less common

Abdominal or stomach pain
bladder pain
bloody or cloudy urine
chest discomfort
chest pain
cough or hoarseness
cough producing mucus
diarrhea
difficult or labored breathing
difficulty with swallowing
dizziness
feeling of warmth
fever or chills
frequent urge to urinate
hives
itching
loss of appetite
lower back or side pain
nausea
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the face, neck, arms, and occasionally, upper chest
runny nose
shortness of breath
skin rash
sore throat
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
unusual tiredness or weakness
weakness
wheezing

Rare

Hives or welts
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
redness of the skin
swelling of the mouth or throat
trouble breathing

Incidence not known

Agitation
anxiety
arm, back, or jaw pain
chest tightness or heaviness
confusion
convulsions
decreased urine
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
dry mouth
extra heartbeats
fainting
flushed, dry skin
fruit-like breath odor
hallucinations
headache
increased hunger
increased thirst
increased urination
irritability
lightheadedness
muscle pain or cramps
nervousness
nightmares
numbness or tingling in the hands, feet, or lips
pounding in the ears
rapid, deep breathing
restlessness
shakiness
slow or fast heartbeat
stomach cramps
sweating
unexplained weight loss
unusual feeling of excitement
vomiting

More common

Body aches or pain
congestion
fever
runny nose
tender, swollen glands in the neck
trouble with swallowing
voice changes

Less common

Difficult, burning, or painful urination
earache
headache, severe and throbbing
muscle or bone pain
pain
redness of the skin
redness or swelling in the ear
redness, swelling, or soreness of the tongue
sleeplessness
sneezing
stuffy nose
swelling
tenderness
trouble in holding or releasing urine
trouble sleeping
unable to sleep
warmth on the skin

Rare

Sleepiness or unusual drowsiness

Incidence not known

Bad, unusual, or unpleasant (after) taste
change in taste
feeling of constant movement of self or surroundings
gagging
rough, scratchy sound to voice
sensation of spinning
tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Comments (0)

Ventolin Aerosol

30/06/10

Generic Name: Albuterol (al-BUE-ter-ol)
Brand Name: Examples include Proventil and Ventolin

Ventolin Aerosol is used for:

Treating or preventing breathing problems in patients who have asthma or certain other airway diseases. It may be used to prevent breathing problems caused by exercise. It may also be used for other conditions as determined by your doctor.

Ventolin Aerosol is a sympathomimetic (beta agonist) bronchodilator. It works by relaxing the smooth muscle in the airway, which allows air to flow in and out of the lungs more easily.

Do NOT use Ventolin Aerosol if:

you are allergic to any ingredient in Ventolin Aerosol
you are using another short-acting sympathomimetic bronchodilator (eg, metaproterenol)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ventolin Aerosol:

Some medical conditions may interact with Ventolin Aerosol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of heart problems, (eg, fast or irregular heartbeat, low blood output), blood vessel problems, high blood pressure, or low blood potassium levels
if you have a history of seizures, diabetes, an overactive thyroid, kidney problems, or an adrenal gland tumor (pheochromocytoma)
if you have ever had an unusual reaction to another sympathomimetic medicine (eg, pseudoephedrine)
if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days

Some MEDICINES MAY INTERACT with Ventolin Aerosol. Tell your health care provider if you are taking any other medicines, especially any of the following:

Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood potassium levels may be increased
Catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), MAOIs (eg, phenelzine), short-acting sympathomimetic bronchodilators (eg, metaproterenol), stimulants (eg, amphetamine), sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Ventolin Aerosol’s side effects
Beta-blockers (eg, propranolol) because they may decrease Ventolin Aerosol’s effectiveness
Digoxin because its effectiveness may be decreased by Ventolin Aerosol

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ventolin Aerosol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ventolin Aerosol:

Use Ventolin Aerosol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Ventolin Aerosol. Talk to your pharmacist if you have questions about this information.
Ventolin Aerosol is for oral inhalation only. Do not spray in the eyes. If you get Ventolin Aerosol in the eyes, rinse immediately with cool tap water.
Prime the inhaler before the first use, any time it has not been used for more than 2 weeks, or if it has been dropped. To prime the inhaler, point it away from you and others. Spray 4 times, shaking well before each spray. If the inhaler has not been used for at least 4 days, re-prime by spraying 2 times.
Before using Ventolin Aerosol, be sure that the canister is properly placed in the inhaler unit. Shake well before each use. Remove the protective cap from the mouthpiece and check to make sure there are no hidden foreign objects. Breathe out slowly and completely. Place the mouthpiece between your lips and try to rest your tongue flat, unless your doctor has told you otherwise. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time. This will release a dose of Ventolin Aerosol. Continue breathing in slowly and deeply and hold for as long as comfortable (up to 10 seconds), then breathe out slowly through pursed lips or your nose. If more than 1 inhalation is to be used, wait 1 minute and repeat the above steps. Keep the spray away from your eyes.
Ventolin Aerosol may cause dry mouth or an unpleasant taste in your mouth. Rinsing your mouth with water after each dose may help relieve these effects.
Clean the plastic mouthpiece and cap at least once a week to prevent blockage. Remove the metal canister. Rinse in warm running water for 30 seconds. Shake off excess water, and then allow the mouthpiece to air dry completely (eg, overnight). After the plastic case and cap dry, replace the canister. Spray 1 time into the air away from yourself and others. Place the cap back on the mouthpiece. Do NOT allow the metal canister to become wet.
If you must use the inhaler before it is completely dry, shake the excess water off of the plastic mouthpiece. Shake the canister well, then insert into the plastic case and spray 1 time into the air away from yourself and others. You may then use a dose. After your dose, rewash the plastic case and air dry completely.
If the inhaler becomes blocked, wash the plastic case as directed.
This inhaler contains 200 sprays. Do not use this inhaler after 200 sprays have been used. It may not give the correct amount of medicine with each spray.
Do not use Ventolin Aerosol with any other mouthpiece. Do not use this mouthpiece with any other medicine.
Do not stop using Ventolin Aerosol without checking with your doctor.
If you miss a dose of Ventolin Aerosol and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ventolin Aerosol.

Important safety information:

Ventolin Aerosol may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ventolin Aerosol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Ventolin Aerosol may sometimes cause severe breathing problems right after you use a dose. When this problem occurs, it is often after the first use of a new canister or vial. If this happens, seek medical care at once.
If your usual dose does not work well, your symptoms become worse, or you need to use it more often than normal, contact your doctor at once. This may be a sign of seriously worsening asthma. Your doctor may need to change your dose or medicine.
Ventolin Aerosol should work for up to 6 hours. Do NOT use more than the recommended dose or use more often than prescribed without checking with your doctor. The risk of severe heart problems and sometimes death may be increased with overuse of Ventolin Aerosol.
Some patients may have trouble using Ventolin Aerosol correctly. Some may also get mouth sores or a bad taste in the mouth after using it. If you have any of these problems, ask your health care provider if a spacing device may help.
Tell your doctor or dentist that you take Ventolin Aerosol before you receive any medical or dental care, emergency care, or surgery.
Talk with your doctor or pharmacist about all of your asthma medicines and how to use them. Do not start, stop, or change the dose of any asthma medicine unless your doctor tells you to.
Keep track of how many inhalations you use. When your medicine supply begins to run low, call your doctor or pharmacy as soon as possible for a refill.
Do NOT place the canister in water to try to determine how much medicine you have left.
The contents of this canister are under pressure. Do NOT puncture, break, or burn container, even if it appears empty.
Diabetes patients – Ventolin Aerosol may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Use Ventolin Aerosol with caution in the ELDERLY; they may be more sensitive to its effects.
Caution is advised when using Ventolin Aerosol in CHILDREN; they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ventolin Aerosol while you are pregnant. It is not known if Ventolin Aerosol is found in breast milk. If you are or will be breast-feeding while you use Ventolin Aerosol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ventolin Aerosol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; headache; nausea; nervousness; sinus inflammation; sore or dry throat; tremor; trouble sleeping; unusual taste in mouth; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; new or worsened trouble breathing; pounding in the chest; severe headache or dizziness; unusual hoarseness; wheezing.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org ), or emergency room immediately. Symptoms may include chest pain; fast or irregular heartbeat; seizures; severe headache or dizziness; severe or persistent nervousness or trouble sleeping; tremor.

Proper storage of Ventolin Aerosol:

Store Ventolin Aerosol upright between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Contents are under pressure. Do not puncture. Do not use or store near heat or open flame. Do not expose the container to temperatures above 120 degrees F (48 degrees C). The container may burst. Store the inhaler with the mouthpiece down. Do not use after the expiration date on the container or box. Keep Ventolin Aerosol out of the reach of children and away from pets.

General information:

If you have any questions about Ventolin Aerosol, please talk with your doctor, pharmacist, or other health care provider.
Ventolin Aerosol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ventolin Aerosol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

Med-facts,V

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Ventolin HFA

30/06/10

Generic name: Albuterol sulfate
Brand names: VoSpire Extended-Release Tablets, AccuNeb, Proventil HFA, Ventolin HFA, Volmax Extended-Release Tablets, Proventil

Why is Ventolin HFA prescribed?

Drugs containing albuterol are prescribed for the prevention and relief of bronchial spasms that narrow the airway. This especially applies to the treatment of asthma. Some brands of Proventil are also used for the prevention of bronchial spasm due to exercise.

Most important fact about Ventolin HFA

Do not take albuterol more frequently than your doctor recommends. Increasing the number of doses can be dangerous and may actually make symptoms of asthma worse.

If the dose your doctor recommends does not provide relief of your symptoms, or if your symptoms become worse, consult your doctor immediately.

How should you take Ventolin HFA?

If you are taking extended-release tablets, swallow them whole with some liquid–never chew or crush them.

Shake the inhalation aerosol canister well before using and make sure it’s firmly seated in the plastic mouthpiece. Before using it for the first time, prime the canister with 4 sprays into the air away from your face. Prime it with 2 sprays whenever it has not been used for at least 4 days. Use only the adapter that comes with the product; do not use this adapter with any other product. Wash the plastic mouthpiece with warm running water at least once a week to prevent medication buildup and blockage.

If you are using an inhalation solution, be sure to protect it from contamination. Keep the tip of the dropper away from the lip of the bottle or any other surface. Do not use the solution if it changes color or becomes cloudy.

–If you miss a dose…

Take the forgotten dose as soon as you remember; then take any remaining doses for that day at equally spaced intervals. Never take a double dose.

–Storage instructions…

AccuNeb, Proventil syrup, and Proventil solution for inhalation can be kept in the refrigerator or at room temperature. Proventil aerosol can be stored at temperatures as low as 60 degrees Fahrenheit, but should be at room temperature before use. Protect from excessive heat.

Ventolin nebules must be used within 2 weeks of being removed from the refrigerator.

Store VoSpire tablets at room temperature in a tight, light-resistant container.

Volmax tablets should be kept refrigerated.

Ventolin HFA side effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking albuterol.

Side effects may include:
Aggression, agitation, allergic reaction, anxiety, back pain, chest pain or discomfort, chills and fever, coordination problems, cough, decreased appetite, depression, difficulty speaking, diabetes, diarrhea, dizziness, drowsiness, dry mouth and throat, excitement, fluid retention and swelling, flushing, general bodily discomfort, headache, heart palpitations, heartburn, hives, increased appetite, increased blood pressure, increased difficulty breathing, indigestion, irritability, labored breathing, leg cramps, light-headedness, muscle cramps, muscle spasm, nasal inflammation, nausea, nervousness, nightmares, nosebleed, overactivity, rapid heartbeat, rash, respiratory infection or disorder, restlessness, ringing in the ears, shakiness, sleeplessness, slowed movement, stomachache, stuffy nose, sweating, swelling of mouth and throat, taste sensation on inhalation, throat irritation, tooth discoloration, tremors, unusual taste, urinary problems, vomiting, weakness, wheezing

Why should Ventolin HFA not be prescribed?

If you are sensitive to or have ever had an allergic reaction to albuterol or other bronchodilators, you should not take Ventolin HFA. Make sure that your doctor is aware of any drug reactions that you have experienced.

Special warnings about Ventolin HFA

When taking albuterol inhalation aerosol, you should not use other inhaled medications before checking with your doctor.

Make sure the doctor is aware of it if you have a heart condition, seizure disorder, high blood pressure, abnormal heartbeat, overactive thyroid gland, or diabetes. Call your doctor immediately if you notice any change in heartbeat or pulse while taking Proventil.

You may have an immediate, serious allergic reaction to the first dose of albuterol, causing symptoms such as hives, rash, and swelling of the mouth, throat, lips, and tongue. The drug has been known to cause life-threatening bronchial spasms, especially with the first dose from a new canister or vial. There have also been rare reports of skin reddening and peeling in children taking albuterol syrup.

Do not exceed your doctor’s recommended dose of albuterol. If you need more than usual, check with your doctor. Your asthma may be getting unstable, and you may need another medication. Do not, however, change your medication without first consulting your doctor or pharmacist.

Possible food and drug interactions when taking Ventolin HFA

Use albuterol inhalation aerosol with other aerosol bronchodilators only if your doctor recommends it.

If albuterol is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining albuterol with the following:

Antidepressants classified as MAO inhibitors, such as Nardil and Parnate, and tricyclic antidepressants such as Elavil, Norpramin, Pamelor, and Tofranil.
Beta blockers (heart and blood pressure drugs such as Inderal, Tenormin, and Sectral)
Digoxin (Lanoxin)
Drugs similar to albuterol, such as Alupent, Brethine, Isuprel, and epinephrine
Drugs that lower potassium levels (water pills such as Lasix or HydroDIURIL)

Special information if you are pregnant or breastfeeding

The effects of albuterol during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether albuterol appears in breast milk. If Proventil is essential to your health, your doctor may advise you to stop nursing your baby until your treatment is finished.

Recommended dosage for Ventolin HFA

ADULTS

Inhalation Aerosol

If you are being treated for a sudden or severe bronchial spasm or the prevention of asthma symptoms, the usual dosage of albuterol inhalation aerosol is 2 inhalations repeated every 4 to 6 hours. More frequent use is not recommended. In some individuals, 1 inhalation every 4 hours may be sufficient.

To prevent exercise-induced bronchial spasm, the usual dosage is 2 inhalations, 15 minutes prior to exercise.

Tablets

The usual starting dose for adults and children 12 years of age and older is 2 or 4 milligrams 3 to 4 times a day. Dosage should not exceed 32 milligrams per day.

Syrup

The usual starting dose for adults and children over 12 years of age is 1 or 2 teaspoonfuls 3 or 4 times a day. Dosage should not exceed 4 teaspoonfuls 4 times a day.

Proventil Inhalation Solution

The usual dosage for adults and children 12 years of age and older is 2.5 milligrams administered 3 to 4 times daily by nebulization. Do not use more often or in higher doses. To administer 2.5 milligrams, use the entire contents of a unit-dose bottle of the 0.083% solution or dilute 0.5 milliliter of the 0.5 percent solution with 2.5 milliliters of sterile normal saline solution.

Proventil Repetabs, Volmax Extended-Release Tablets, and VoSpire Extended-Release Tablets

The usual recommended dosage for adults and children 12 years of age and older is 8 milligrams every 12 hours. In some people, 4 milligrams every 12 hours may be sufficient. If the desired effect is not achieved with the standard dosage, your doctor may increase doses to a maximum of 32 milligrams per day, divided into two 16-milligram doses spaced 12 hours apart. Those taking standard tablets or syrup can switch to extended-release tablets. One extended-release tablet every 12 hours is equivalent to one 2-milligram standard tablet every 6 hours.

CHILDREN

Inhalation Aerosol

The usual dose of albuterol inhalation aerosol for children aged 4 and over (12 and over for Proventil) is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchial spasm, the dose is 2 inhalations 15 minutes prior to exercise.

Tablets

The usual starting dose for children 6 to 12 years of age is 2 milligrams 3 or 4 times a day. The dose can be increased with caution but should not exceed 24 milligrams per day. Safety and effectiveness in children under 6 have not been established.

Syrup

The usual starting dose for children 6 to 12 years of age is 1 teaspoonful 3 to 4 times a day. The dosage should not exceed 3 teaspoonfuls 4 times a day. For children 2 to 6 years of age, the starting dose is 0.1 milligram per 2.2 pounds of body weight, to a maximum of 4 milligrams, 3 times a day.

Proventil Repetabs, Volmax Extended-Release Tablets, and VoSpire Extended-Release Tablets

The usual starting dosage for children 6 to 12 years of age is 4 milligrams every 12 hours. The dosage can be increased with caution but should not exceed 24 milligrams per day.

AccuNeb Inhalation Solution

The usual starting dose for children 2 to 12 years of age is 0.63 or 1.25 milligrams 3 or 4 time daily by nebulization. To administer, use the entire contents of the prescribed unit-dose vial. The 1.25 milligram dosage may be more helpful for children 6 to 12 with more severe asthma, and for children 11 to 12.

OLDER ADULTS

Oral Dosage

The usual starting dose of tablets or syrup is 2 milligrams 3 or 4 times a day. If needed, the dosage may be increased gradually to as much as 8 milligrams 3 or 4 times a day.

Overdosage

Symptoms of albuterol overdose may include:
Dizziness, dry mouth, fatigue, general feeling of illness, headache, high or low blood pressure, insomnia, nausea, nervousness, radiating chest pain, rapid or irregular heartbeat, seizures, tremors

Heart attack and even death have been associated with abuse of albuterol inhalation. Exaggerated side effects may also be a sign of an overdose. If you suspect an overdose, seek medical attention immediately.

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Ventolin HFA Aerosol

30/06/10

Generic Name: Albuterol (al-BUE-ter-ol)
Brand Name: Ventolin HFA

Ventolin HFA Aerosol is used for:

Ventolin HFA Aerosol is a sympathomimetic (beta agonist) bronchodilator. It works by relaxing the smooth muscle in the airway, which allows air to flow in and out of the lungs more easily.

Do NOT use Ventolin HFA Aerosol if:

you are allergic to any ingredient in Ventolin HFA Aerosol
you are using another short-acting sympathomimetic bronchodilator (eg, metaproterenol)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ventolin HFA Aerosol:

Some medical conditions may interact with Ventolin HFA Aerosol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have a history of heart problems, (eg, fast or irregular heartbeat, low blood output), blood vessel problems, high blood pressure, or low blood potassium levels
if you have a history of seizures, diabetes, an overactive thyroid, kidney problems, or an adrenal gland tumor (pheochromocytoma)
if you have ever had an unusual reaction to another sympathomimetic medicine (eg, pseudoephedrine)
if you are taking a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) or tricyclic antidepressant (eg, amitriptyline), or if you have taken either of these medicines within the last 14 days

Some MEDICINES MAY INTERACT with Ventolin HFA Aerosol. Tell your health care provider if you are taking any other medicines, especially any of the following:

Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood potassium levels may be increased
Catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), MAOIs (eg, phenelzine), short-acting sympathomimetic bronchodilators (eg, metaproterenol), stimulants (eg, amphetamine), sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Ventolin HFA Aerosol’s side effects
Beta-blockers (eg, propranolol) because they may decrease Ventolin HFA Aerosol’s effectiveness
Digoxin because its effectiveness may be decreased by Ventolin HFA Aerosol

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ventolin HFA Aerosol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ventolin HFA Aerosol:

Use Ventolin HFA Aerosol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with Ventolin HFA Aerosol. Talk to your pharmacist if you have questions about this information.
Ventolin HFA Aerosol is for oral inhalation only. Do not spray in the eyes. If you get Ventolin HFA Aerosol in the eyes, rinse immediately with cool tap water.
Prime the inhaler before the first use, any time it has not been used for more than 2 weeks, or if it has been dropped. To prime the inhaler, point it away from you and others. Spray 4 times, shaking well before each spray.
Before using Ventolin HFA Aerosol, be sure that the canister is properly placed in the inhaler unit. Shake well before each use. Remove the protective cap from the mouthpiece and check to make sure there are no hidden foreign objects. Breathe out slowly and completely. Place the mouthpiece fully into the mouth and close the lips around it , unless your doctor has told you otherwise. Your doctor may have told you to hold the inhaler 1 or 2 inches (2 or 3 centimeters) away from the open mouth or to use a special spacing device. As you start to take a slow deep breath, press the canister and mouthpiece together at exactly the same time. This will release a dose of Ventolin HFA Aerosol. Continue breathing in slowly and deeply and hold for as long as comfortable (up to 10 seconds), then breathe out slowly through pursed lips or your nose. If more than 1 inhalation is to be used, wait 1 minute and repeat the above steps. Keep the spray away from your eyes.
Ventolin HFA Aerosol may cause dry mouth or an unpleasant taste in your mouth. Rinsing your mouth with water after each dose may help relieve these effects.
Clean the plastic mouthpiece and cap at least once a week to prevent blockage. Remove the metal canister. Rinse in warm running water for 30 seconds. Shake off excess water, and then allow the mouthpiece to air dry completely (eg, overnight). After the plastic case and cap dry, replace the canister. Spray 1 time into the air away from yourself and others. Place the cap back on the mouthpiece. Do NOT allow the metal canister, including the counter, to become wet.
If you must use the inhaler before it is completely dry, shake the excess water off of the plastic mouthpiece. Shake the canister well, then insert into the plastic case and spray 1 time into the air away from yourself and others. You may then use a dose. After your dose, rewash the plastic case and air dry completely.
If the inhaler becomes blocked, wash the plastic case as directed.
This inhaler contains 200 sprays. Do not use this inhaler after 200 sprays have been used (when the counter on the inhaler says “000″) or if it has been out of the moisture-protective foil pouch for longer than 2 months. It may not give the correct amount of medicine with each spray.
Do not use Ventolin HFA Aerosol with any other mouthpiece. Do not use this mouthpiece with any other medicine.
Do not stop using Ventolin HFA Aerosol without checking with your doctor.
If you miss a dose of Ventolin HFA Aerosol and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ventolin HFA Aerosol.

Important safety information:

Ventolin HFA Aerosol may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Ventolin HFA Aerosol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Ventolin HFA Aerosol may sometimes cause severe breathing problems right after you use a dose. When this problem occurs, it is often after the first use of a new canister or vial. If this happens, seek medical care at once.
If your usual dose does not work well, your symptoms become worse, or you need to use it more often than normal, contact your doctor at once. This may be a sign of seriously worsening asthma. Your doctor may need to change your dose or medicine.
Ventolin HFA Aerosol should work for up to 4 to 6 hours. Do NOT use more than the recommended dose or use more often than prescribed without checking with your doctor. The risk of severe heart problems and sometimes death may be increased with overuse of Ventolin HFA Aerosol.
Some patients may have trouble using Ventolin HFA Aerosol correctly. Some may also get mouth sores or a bad taste in the mouth after using it. If you have any of these problems, ask your health care provider if a spacing device may help.
Tell your doctor or dentist that you take Ventolin HFA Aerosol before you receive any medical or dental care, emergency care, or surgery.
Talk with your doctor or pharmacist about all of your asthma medicines and how to use them. Do not start, stop, or change the dose of any asthma medicine unless your doctor tells you to.
When your medicine supply begins to run low (eg, the counter reaches “020″), call your doctor or pharmacy as soon as possible for a refill.
Do NOT try to change the numbers on the counter. Do NOT place the canister in water to try to determine how much medicine you have left.
The contents of this canister are under pressure. Do NOT puncture, break, or burn container, even if it appears empty.
Diabetes patients – Ventolin HFA Aerosol may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Use Ventolin HFA Aerosol with caution in the ELDERLY; they may be more sensitive to its effects.
Ventolin HFA Aerosol should be used with extreme caution in CHILDREN younger than 4 years old; safety and effectiveness in these children have not been confirmed.
Caution is advised when using Ventolin HFA Aerosol in CHILDREN; they may be more sensitive to its effects.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ventolin HFA Aerosol while you are pregnant. It is not known if Ventolin HFA Aerosol is found in breast milk. If you are or will be breast-feeding while you use Ventolin HFA Aerosol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ventolin HFA Aerosol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; headache; nervousness; sinus inflammation; sore or dry throat; tremor; trouble sleeping; unusual taste in mouth.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; new or worsened trouble breathing; pounding in the chest; severe headache or dizziness; unusual hoarseness; wheezing.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include chest pain; fast or irregular heartbeat; seizures; severe headache or dizziness; severe or persistent nervousness or trouble sleeping; tremor.

Proper storage of Ventolin HFA Aerosol:

Store Ventolin HFA Aerosol upright between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Contents are under pressure. Do not puncture. Do not use or store near heat or open flame. Do not expose the container to temperatures above 120 degrees F (48 degrees C). The container may burst. Store the inhaler with the mouthpiece down. Throw away this inhaler 2 months after it has been removed from the moisture-protective foil pouch. Do not use after the expiration date on the container or box. Keep Ventolin HFA Aerosol out of the reach of children and away from pets.

General information:

If you have any questions about Ventolin HFA Aerosol, please talk with your doctor, pharmacist, or other health care provider.
Ventolin HFA Aerosol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ventolin HFA Aerosol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: May 5, 2010

Database Edition 10.2.1.002

Med-facts,V

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Ventolin

30/06/10

Generic Name: albuterol (Oral route)

al-BUE-ter-ol

Commonly used brand name(s):

In the U.S.

Proventil
Proventil Repetabs
Ventolin
Volmax
VoSpire ER

In Canada

Apo-Salvent Inhaler

Available Dosage Forms:

Tablet
Syrup
Tablet, Extended Release

Therapeutic Class: Bronchodilator

Pharmacologic Class: Sympathomimetic

Uses For Ventolin

Albuterol is used to treat bronchospasm or wheezing in patients with reversible obstructive airway disease, such as asthma.

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor’s prescription.

Before Using Ventolin

Allergies

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of albuterol in children 2 years of age and older.

Geriatric

No information is available on the relationship of age to the effects of albuterol in geriatric patients. However, elderly patients are more likely to have age-related heart problems, which may require caution and an adjustment in the dose for patients receiving albuterol.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Acebutolol
Alprenolol
Arotinolol
Atenolol
Atomoxetine
Befunolol
Betaxolol
Bevantolol
Bisoprolol
Bopindolol
Brofaromine
Bucindolol
Bupranolol
Carteolol
Carvedilol
Celiprolol
Clorgyline
Dilevalol
Esmolol
Furazolidone
Iproniazid
Isocarboxazid
Labetalol
Landiolol
Lazabemide
Levobetaxolol
Levobunolol
Linezolid
Mepindolol
Metipranolol
Metoprolol
Moclobemide
Nadolol
Nebivolol
Nialamide
Nipradilol
Oxprenolol
Pargyline
Penbutolol
Phenelzine
Pindolol
Procarbazine
Propranolol
Rasagiline
Selegiline
Sotalol
Talinolol
Tertatolol
Timolol
Toloxatone
Tranylcypromine

Interactions with Food/Tobacco/Alcohol

Proper Use of albuterol

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Ventolin. Please read with care.

Swallow the extended-release tablet whole with water or liquids. Do not break, crush, or chew the tablet.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Dosing

For treatment of bronchospasm:
- For oral dosage form (syrup, tablets):
  - Adults and children older than 12 years of age—2 or 4 milligrams (mg) taken 3 or 4 times per day. Your doctor may increase your dose as needed up to a maximum of 32 mg per day, divided and given 4 times per day.
  - Children 6 to 12 years of age—2 mg taken 3 or 4 times per day. Your doctor may increase your dose as needed up to a maximum dose of 24 mg per day, divided and given 4 times per day.
  - Children 2 to 6 years of age—Dose is based on body weight and must be determined by your doctor. The usual dose is 0.1 milligram (mg) per kilogram (kg) of body weight per dose, given 3 times per day, and each dose will not be more than 2 mg. Your doctor may increase your dose as needed up to a maximum dose of 12 mg per day, divided and given 3 times a day.
  - Children younger than 2 years of age—Use and dose must be determined by your child’s doctor.
- For oral dosage form (extended-release tablets):
  - Adults and children older than 12 years of age—8 milligrams (mg) every 12 hours. Your doctor may increase your dose as needed up to a maximum of 32 mg per day, divided and given every 12 hours.
  - Children 6 to 12 years of age—4 mg every 12 hours. Your doctor may increase your dose as needed up to a maximum dose of 24 mg per day, divided and given every 12 hours.
  - Children younger than 6 years of age—Use and dose must be determined by your child’s doctor.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Ventolin

Ventolin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet

Less common

Fast, irregular, pounding, or racing heartbeat or pulse

Rare

Cough
difficulty breathing
difficulty with swallowing
hives or welts
hoarseness
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
noisy breathing
redness of the skin
shortness of breath
skin rash
slow or irregular breathing
swelling of the mouth or throat
tightness in the chest
wheezing

Incidence not known

Agitation
anxiety
arm, back, or jaw pain
blurred vision
chest pain or discomfort
confusion
convulsions
extra heartbeats
fainting
hallucinations
headache
irritability
lightheadedness
mood or mental changes
muscle pain or cramps
muscle spasm or jerking of all extremities
nervousness
nightmares
pounding in the ears
restlessness
sudden loss of consciousness
sweating
total body jerking
unusual feeling of excitement
vomiting

Less common

Dizziness
feeling of warmth
irritability
nausea
redness of the face, neck, arms, and occasionally, upper chest
sleeplessness
trouble with holding or releasing urine
trouble sleeping
unable to sleep

Rare

Sleepiness
unusual drowsiness

Incidence not known

Bad, unusual, or unpleasant (after) taste
change in taste
feeling of constant movement of self or surroundings
gagging
rough, scratchy sound to voice
sensation of spinning
tightness in the throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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